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Viagra

Viagra is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, sildenafil helps to maintain an erection after the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, sildenafil will not work to cause an erection.

Other names for this medication:
Caverta, Intagra, Kamagra, Penegra, Revatio, Silagra, Sildenafil, Sildenafila, Sildenafilo, Sildenafilum, Sildigra, Suhagra, Veega, Zenegra

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Also known as: Sildenafil

Description

Sildenafil citrate was the first medicine formulated for the treatment of male impotence in the year 1998 by the researchers of drug manufacturing company Pfizer. The drug is also used for the treatment of the pulmonary arterial hypertension which is rare pulmonary disorder that occurs in mountaineers and people living at high altitude.

Millions of individuals visit their doctors after suffering from erectile dysfunction or male impotence. The doctors will look after the individual's health record for all the ailments and give out best possible treatment. Most of the individuals are prescribed with sildenafil citrate for the cure of impotence. This is the 1st line of treatment opted by all the physicians in case of impotence in men.

People who cannot get proper erection is on sexual stimulation needed sildenafil 100mg. This medicine will help in improvement of blood flow to the muscles of penis. As the blood flow increases owing to sexual stimulation and erection takes place, the man can indulge into sexual activity and perform to satisfaction. This medicine has helped millions of individuals to save their relationships that would have been devastated because of impotence.

Dosage

Take Viagra exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Viagra is usually taken only when needed, 30 minutes to 1 hour before sexual activity. You may take it up to 4 hours before sexual activity. Do not take Viagra more than once per day.

Viagra can help you have an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor's instructions.

During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of sildenafil.

Store at room temperature away from moisture and heat.

Detailed Viagra dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Viagra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Viagra can interact with several other medications. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Viagra and other medications

Below are lists of medications that can interact with Viagra. These lists don’t contain all the drugs that may interact with Viagra.

Before taking Viagra, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Viagra and other ED medications

You shouldn’t take Viagra with any other medications for erectile dysfunction (ED). This includes prescription medications, such as:

  • tadalafil (Cialis)
  • avanafil (Stendra)
  • vardenafil (Levitra, Staxyn)
  • alprostadil (Muse, Caverject, Caverject Impulse, Edex)
It also includes natural or over-the-counter ED treatments, such as l-arginine and yohimbine.

Taking Viagra with other ED medications increases your risk of certain side effects, such as low blood pressure and priapism.*

If you’re using Viagra, don’t use any other medications for ED without talking with your doctor.

* Priapism is a long-lasting and sometimes painful erection that doesn’t go away. It’s a medical emergency because it can damage the tissues in your penis and lead to permanent ED.

Viagra and nitrates

You shouldn’t take Viagra with nitrate drugs. This includes certain prescription drugs, such as nitroglycerin, used to treat angina (a type of chest pain). It also includes certain illicit drugs called poppers, such as amyl nitrate.

Taking Viagra with nitrates can cause a dangerous drop in your blood pressure that can lead to heart attack or stroke.

Examples of nitrate drugs that should not be taken with Viagra include:

  • nitroglycerin (Nitromist, Nitro-Dur, Nitrolingual Pumpspray, Gonitro, others)
  • isosorbide mononitrate (Monoket)
  • isosorbide dinitrate (Dilatrate SR, Isordil)
  • glyceryl trinitrate
  • amyl nitrate
  • alkyl nitrate
  • butyl nitrate

Viagra and drugs for pulmonary arterial hypertension

You shouldn’t take Viagra if you’re taking the pulmonary arterial hypertension (PAH)* drugs listed below. Taking Viagra with these medications can cause your blood pressure to drop too low.

Examples of drugs used to treat PAH that should not be taken with Viagra include:

  • riociguat (Adempas)
  • sildenafil (Revatio)
  • tadalafil (Adcirca)
* With PAH, you have <em>high blood pressure</em> in the artery between your heart and lungs.

Viagra and blood pressure drugs

Viagra can sometimes cause low blood pressure. Taking Viagra with drugs used to treat high blood pressure can cause your blood pressure to drop even lower.

Examples of drugs used to treat high blood pressure include:

  • calcium channel blockers, such as amlodipine (Norvasc)
  • beta-blockers, such as metoprolol (Lopressor, Toprol-XL)
  • ACE inhibitors, such as lisinopril (Zestril, Prinivil)
  • angiotensin II receptor blockers, such as losartan (Cozaar)
If you take a drug for high blood pressure, your doctor might prescribe a dose of Viagra for you that’s lower than the typical dose.

Viagra and alpha-blockers

If you’re taking a type of blood pressure drug called an alpha-blocker, the extra drop in blood pressure from Viagra could make you feel dizzy or lightheaded. It could even make you faint. If you’re taking an alpha-blocker, your doctor will recommend a starting dose of 25 mg of Viagra, which is lower than the usual starting dose.

Examples of alpha-blocker drugs used for high blood pressure include:

  • doxazosin (Cardura)
  • prazosin (Minipress)
  • terazosin
If you take one of the drugs listed above, tell your doctor if you feel dizzy or lightheaded, or faint after taking Viagra.

Viagra and illicit drugs

You shouldn’t take Viagra with illicit drugs called poppers. Poppers contain nitrate drugs such as amyl nitrate, alkyl nitrate, and butyl nitrate. Taking Viagra with poppers can cause a dangerous drop in your blood pressure that can lead to heart attack or stroke.

Viagra hasn’t been tested for use with illicit drugs other than poppers. But it’s possible that taking Viagra with certain other illicit drugs could also have dangerous effects on your heart and blood pressure.

Examples of illicit drugs that could have dangerous effects if taken with Viagra include:

  • stimulants, such as cocaine, ecstasy, amphetamines, and speed
  • anabolic steroids
If you’re thinking of using illicit drugs with Viagra, talk with your doctor about whether this is safe for you to do.

Viagra and certain BPH drugs

Viagra can sometimes cause low blood pressure. Certain drugs used to treat benign prostatic hyperplasia (BPH)* can also cause low blood pressure. These drugs are called alpha-blockers.

Taking Viagra with alpha-blockers can cause your blood pressure to drop even lower. This could make you feel dizzy or lightheaded, or even cause you to faint.

Examples of alpha-blockers that are used to treat BPH include:

  • alfuzosin (Uroxatral)
  • doxazosin (Cardura)
  • tamsulosin (Flomax)
  • silodosin (Rapaflo)
  • terazosin
If you’re taking an alpha-blocker, your doctor will recommend a starting dose of 25 mg of Viagra, which is lower than the usual starting dose. And if you take one of the drugs listed above, tell your doctor if you feel very dizzy, lightheaded, or faint after taking Viagra.

* With BPH, you have an enlarged prostate.

Viagra and Adderall

Viagra hasn’t been tested for use with Adderall, so it’s not known what effects the drugs would have if taken together. But that doesn’t mean there wouldn’t be an interaction.

Adderall, which contains amphetamine salts, is approved to treat attention deficit hyperactivity disorder (ADHD). Adderall has stimulant effects in your body, and it could cause serious heart-related side effects.

Viagra, on the other hand, may cause low blood pressure. So it’s possible that taking it with Adderall could have dangerous effects on your heart or blood pressure.

If you take Adderall, ask your doctor if it’s safe for you to take Viagra as well.

Viagra and Xanax

Viagra hasn’t been tested for use with Xanax, so it’s not known what effects the drugs would have if taken together. But that doesn’t mean there wouldn’t be an interaction.

Xanax, which is a benzodiazepine, contains the active drug alprazolam. Xanax can sometimes cause low blood pressure, dizziness, and fainting. Viagra may also lower your blood pressure. So it’s possible that taking it with Xanax could have dangerous effects on your heart or blood pressure.

If you take Xanax, ask your doctor if it’s safe for you to take Viagra as well.

Viagra and antidepressants

It’s usually fine to take Viagra with antidepressants. It’s important to note that erectile dysfunction (ED) is a common side effect of certain antidepressants. This is particularly true for selective serotonin reuptake inhibitors (SSRIs), such as sertraline (Zoloft). And Viagra is sometimes prescribed to treat ED that’s caused by antidepressants.

If you have questions about whether you can take Viagra with an antidepressant, talk with your doctor.

Viagra and certain antimicrobials

Taking Viagra with certain antimicrobials (drugs used to treat infection) can slow the breakdown of Viagra in your body. This can cause Viagra to build up inside your body, which may increase your risk of side effects from the drug.

Examples of antimicrobial drugs that can increase the risk of side effects from Viagra include:

  • certain antibiotics, such as:
    • clarithromycin
    • erythromycin
    • telithromycin (Ketek)
  • certain antifungals, such as:
    • ketoconazole (Nizoral)
    • itraconazole (Sporanox)
    • posaconazole (Noxafil)
    • voriconazole (Vfend)
  • certain antivirals used for HIV, such as:
    • atazanavir (Reyataz)
    • cobicistat (Tybost)
    • ritonavir (Norvir)
    • indinavir sulfate (Crixivan)
    • nelfinavir mesylate (Viracept)
    • saquinavir mesylate (Invirase)
If you take one of the drugs listed above, your doctor will recommend you take a starting dose of 25 mg for Viagra. (This is lower than the typical starting dose of Viagra.) And if you take ritonavir, you shouldn’t take more than one 25-mg dose of Viagra within a 48-hour period.

Viagra and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Viagra. However, you should still check with your doctor or pharmacist before using any of these products while taking Viagra.

Viagra and foods

There aren’t any foods that have been specifically reported to interact with Viagra. If you have any questions about eating certain foods with Viagra, talk with your doctor.

Viagra and grapefruit

Grapefruit juice can affect the levels of some medications in your body. But there’s not much evidence to show that the fruit or its juice can affect Viagra levels.

One small study was done in 2002. It showed that drinking grapefruit juice with Viagra slightly increased people’s blood level of the drug. This could possibly increase the risk of certain side effects such as headaches, flushing, or dizziness. But these side effects weren’t specifically reported in the study.

If you want to drink grapefruit juice or eat grapefruit while you’re taking Viagra, talk with your doctor. They can recommend whether this is safe for you to do. If you do have increased side effects with this combination, try avoiding grapefruit while you’re taking Viagra.

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Long-term morphological and hormonal follow-up in a single unit on 115 patients with adrenal incidentalomas. A novel methodology for the formation of block copolymers has been developed that combines ring-opening metathesis polymerization (ROMP) with functional chain-transfer agents (CTAs) and self-assembly. The RADAI was analyzed for total scores (range 0-48), number of involved joint groups (range 0-16), and each specific joint group, and then compared in the 5 diagnostic groups to one another and to other MDHAQ measures and the Routine Assessment of Patient Index Data 3 (RAPID3). Many have sought to develop orally available low molecular weight synthetic kinase modulators (predominantly inhibitors) and thus capitalize on the links between aberrant regulation and disease. Although neither method of costimulation required de novo kemadrin 5mg tabs protein synthesis for their effects on IFN-gamma mRNA expression, these molecules used distinct mechanisms. These results reveal a role of the MEK5-ERK5 pathway in modulating the function of the Fos family proteins which is different from the role of the ERK1/2 pathway.

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Surgical considerations in the treatment of ventricular septal defect associated with aortic valvular incompetence. For the correct determination of cup orientation pelvic tilt in relation to the frontal plane has to be accounted for. The results suggest that current prednisolone dosing early after liver transplantation might be too high, in particular when coadministered with methylprednisolone. This paper provides arguments for the implementation of a health monitoring system and the need for long-term funding. Cytokeratins (CKs) like CK 19 and CK 20 are known to be useful diagnostic and prognostic markers for solid tumors. YM022, a potent and selective cholecystokinin-B receptor antagonist, was administered in a maximally effective dose by continuous subcutaneous infusion for 4 weeks (via osmotic minipumps). Elastin composition of human skin chronically exposed to the sun. The mainstay in the management of invasive bladder cancer continues to be radical cystectomy. A 46-year-old woman had an episode of atrial fibrillation during infusion of docetaxel as adjuvant chemotherapy for an infiltrating ductal carcinoma of the breast. To investigate the roles of dendritic cells (DCs) in the pathogenesis of asthma.

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We calculated the risk of liver problems among hepatitis B vaccinated and non-hepatitis B vaccinated children using logistic regression. The first molar as the 3D reconstruction showed was single rooted with one C-shaped root canal with two foramens, while the second one was double rooted with two root canals, one C-shaped and one thin, having a common foramen. The study of the changes in the nuclear domains was determined by a correlative approach at confocal and electron microscopy levels. Lipid composition of subcellular particles of human blood platelets. Glycolysis as an energy source for stimulation of lymphocytes by phytohemagglutinin. In correctly indicated, and if possible early cases of hepatic tumourous affections, it is possible to potentiate the effect of regional chemotherapy by local destruction of tumourous foci by alcoholization, cryodestruction or resection.

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Caregiver characteristics influenced the change in sense of competence but did not influence the risk for institutionalization. Cytokines participate in neuronal death induced by trimethyltin in the rat hippocampus via type II glucocorticoid receptors. The LSI appears to have the properties of a reliable, unidimensional index, in which the item variables are true components of the overall attribute, that is, laparoscopic skill. Electrodes with extremely high hydrogen overvoltages as substrate electrodes for stripping analysis based on bismuth-coated electrodes. HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) pathophysiology and anesthetic considerations. Health promotion, possibly workplace-based, presents opportunities to safeguard the health of nurses. Peritransplant management of retained native kidneys in autosomal dominant polycystic kidney disease. However, given the high prevalence of zantac generic lawsuit this disease and the increasing incidence of microbial resistance to antibiotics, there is a need to develop alternative therapeutic strategies such as vaccination.

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The influence of citrus rootstocks on the relationship between the mite Brevipalpus phoenicis and citrus leprosis disease. Using attenuated total reflectance (ATR)-FT-IR, the residual silanol groups in each hydrogels could be measured without drying procedures and it was found that electroosmotic mobility decreased with a reduction in the residual silanol groups. To evaluate the efficacy of superovulation and IUI versus no treatment for infertility associated with minimal or mild endometriosis. Is the process by which this occurs similar in different lineages?. While thickness increased, the values of optical density in both Digora and DentScan DentView tended to approach each other. The host cells also acquired genetic information from their symbionts, eventually incorporating much of it into their own genomes. Limitations to increase the encapsulation efficiency are caused by the enclosed aqueous volume, by the lipid concentration, the aspired vesicle size and the final ethanol concentration. Biological characterization revealed that osteogenic markers are expressed using both osteogenic and maintenance conditions.

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The presence of a haemolytic component and the type of hypochromic microcytic anaemia in kala-azar. A review of North American Recent Radiolucina (Bivalvia, Lucinidae) with the description of a new species. To describe a hairdresser, who developed contact dermatitis, rhinoconjuntivitis, and bronchial asthma of delayed onset after occupational exposure to hair bleaches containing persulfate salts and to provide evidence for a common T-cell mediated mechanism responsible for the clinical manifestations. Vaccine-induced immune responses also depend upon adequate maxolon dosage in pregnancy upregulation of B7 costimulation molecules, but this signal may be limiting for replication-defective virus vaccines. Toxic megacolon--unusual complication of pseudomembranous colitis. The most dreaded complication of a colonoscopy is colonic perforation.

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Triacylglycerols (TAGs) from microalgae have the potential to be used for biodiesel, but several technical and economic hurdles have to be overcome. In order to determine if this gene segment is used by lower primates in a similar manner we determined the molecular structure of the variable region gene segments that are expressed by macaque monoclonal heterohybridomas that are specific for human red blood cell antigens. The alkanes were characterized by gas chromatography arava 20 mg generic and mass spectrometry. The present study assessed the ability of suckling rats to express short-term behavioral sensitization to cocaine prior to weaning. In this report we show that the treatment of cultured hippocampal astrocytes with tenascin-C results in an increased fibronectin and NCAM immunoreactivities.

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Pyogenic liver abscess (PLA) has been reported as an early manifestation of colorectal cancer (CRC) in adults, but few studies have investigated this relationship. We found that the difference in expression between G2 and G3 stage was statistically relevant in cases of c-Met receptor. AA, which is the primary oxidative metabolite of ethanol, is considered to possess carcinogenic activity. Proteins that contain non-native modified thiols can become destablized such that they unfold into molten globule-like intermediates at or below 37 degrees C, relieving Hsf-1 negative regulation, and inducing Hsp transcription. Blood changes in calcium and magnesium ion concentrations after whole-body x-irradiation.

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Under a gene x environment interaction model for the risk of CRC, it is postulated that a high proportion of the variation in CRC incidence among populations is attributable to differences in diet, and that the prilosec generic vs pantoprazole average genetic susceptibility of populations to dietary carcinogenic components is similar. The induction of COX-2 protein by the cytokine mixture was attenuated by dexamethasone (100 nM), whereas the level of COX-1 protein was unaffected by either the cytokines or by dexamethasone. Other tumors, whether mucin-producing or not, have been found to consistently lack these structures. For each staging system, a linear regression model was created comparing mean hormone values (inhibin B, FSH, LH, E2) and menopausal stages at each assessment. (Because of the nature of the relationship between serum creatinine and creatinine clearance, rise in serum creatinine was divided by pretreatment creatinine squared.) Patients were dichotomized into the upper quartile versus the lower three quartiles of degree of nephrotoxicity. Two-stage resection for malignant colonic obstructions: the timing of early resection and possible predictive factors. Cultured human malignant melanoma cells, when added to normal human lymphocytes stimulated to proliferate by mitogen or antigen, were found to inhibit the uptake of 3H-thymidine (3H-T) by the lymphocytes.

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Changes in cytosolic calcium and postsynaptic responsiveness to acetylcholine were not affected by electrical coupling. Serum VEGF165 levels do not correlate with uterine fibroid volume, but demonstrate a significant decrease after hysterectomy. Role of percutaneous gastrostomy tubes in the postoperative care of patients with cancer of the oral cavity and oropharynx. The case herds had more than 30 cattle, and herds in which the source of infection had been ascribed to purchased cattle were avoided. As TNF induces cellular stress and activates several stress-sensitive cascades that may play a role in apoptosis, TNF-induced stress signaling was examined in MCF-7 cells and compared with a variant MCF-7 cell line resistant to TNF-mediated apoptosis (MCF-7/3E9). Early tissue distribution of therapeutic 131I in a patient with thyrotoxicosis. Craniofacial osteotomies are an integral part of contemporary neurosurgery because of their ability to provide substantially more exposure to deepseated lesions with reduced brain retraction.

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