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Skelaxin (Metaxalone)
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Skelaxin

Skelaxin is a muscle relaxer. It provides relief from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness, and muscle spasms.

Other names for this medication:
Fenaplus, Flexura, Metadol, Metaxalone, Mobiswift, Skeltab

Similar Products:
Depakote, Biaxin, Asacol, Elocon, Nuvigil, Imodium, Panadol

Also known as: Metaxalone

Description

{name} (metaxalone) is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain.

{name} is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Dosage

Usual Adult Dose for Muscle Spasm:

800 mg orally 3 to 4 times a day.

Usual Pediatric Dose for Muscle Spasm:

>= 12 years: 800 mg orally 3 to 4 times a day.

Detailed Skelaxin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of metaxalone can be fatal.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Flammable: Keep away from fire or flame.

Detailed Minoxidil topical dosage information

Side effects

The most common side effects associated with Skelaxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Skelaxin if you are allergic to metaxalone, or if you have:

anemia (low red blood cells); severe kidney disease; or severe liver disease.

To make sure Skelaxin is safe for you, tell your doctor if you have liver or kidney disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether metaxalone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Skelaxin is not approved for use by anyone younger than 12 years old.

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Mechanisms and management of hyperosmolar coma without ketoacidosis in the diabetic. We report the case of a child with TTP 3 years after autologous PBSC transplantation, in whom remission was achieved by administration of cyclosporin A, after failure of plasmapheresis as primary treatment. To determine the impact of sitting and television viewing on life expectancy in the USA. The theoretical description of the anomalous properties of the pseudogap phase in the underdoped region of the cuprate phase diagram lags behind the progress in spectroscopic and other experiments. Furan substituted diketopyrrolopyrrole (DBF) combined with benzothiadiazole based polymer semiconductor PDPP-FBF has been synthesized and evaluated as an ambipolar semiconductor in organic thin-film transistors. Multiple ion association in supercritical aqueous solutions of single electrolytes. CNTF induced SOCS-3 mRNA and SOCS-3 protein levels in an astrocyte cell line. Interaction between medullary and spinal delta1 and delta2 opioid receptors in the production of antinociception in the rat.

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In a controlled study, production of alpha-waves rose significantly, while delta-activity decreased. Two intracellular recording studies of V1, one using naturalistic stimuli (Haider et al., 2010), the other sinusoidal gratings (Ozeki et al., 2009), sought to identify the causes of reduced activity in V1 with increasing stimulus size, a hallmark of surround suppression. The modification of PCNA with monoubiquitin signals an error-prone bypass, whereas the extension of this modification into a Lys-63-linked polyubiquitin chain promotes error-free bypass. Daily telephone follow-up was conducted until complete resolution of sore throat. Critical characterization needs include qualitative and quantitative determination of the chemical forms of carbon, oxygen, nitrogen, and sulfur and reliable methods for the measurement of surface area, pore volume, and weight-average molecular weights. Animal models of osteoarthritis (OA) are used to study the pathogenesis of cartilage degeneration and to evaluate potential anti-arthritic drugs for clinical use.

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Their potential use in vivo prompted us to study their effects on the immune system. After standard laparoscopic mobilization of the distal stomach, a small duodenotomy is made just distal to the pyloric ring. Vagus Nerve Stimulation for Patients in Residential Treatment Facilities. While in one family the males were mainly affected, in the second faimily the females were mainly affected with congenital cataract. The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses. These results do not support the hypothesis that P230 BCR/ABL induces a distinct and less aggressive form of CML in humans, and suggest that the rarity of P190 BCR/ABL in human CML may reflect infrequent BCR intron 1 breakpoints during the genesis of the Ph chromosome in stem cells, rather than intrinsic differences in myeloid leukemogenicity between P190 and P210. Fabry Disease (FD) is a lysosomal storage disease associated with cardiomyopathy, early-onset stroke, renal failure, among other features. The objective of this study was to examine the psychometric properties and clinical correlates of the 20-item Toronto Alexithymia Scale (TAS-20) in patients with psoriasis. By personalizing the process of seeking and receiving information and allowing patients to specify their desire for information in a prospective manner, we aim to shift genuine control over the informational process to patients. Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway.

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Within the WHO MONICA Project, stroke has been recorded in 18 populations in 11 countries. In contrast to extremity sarcoma, postoperative radiation therapy (RT) has shown limited efficacy due to its limitations in achievable dose and coverage. The crucial point regarding non-toxic nodular goiter is the early diagnosis of neoplasm. It is concluded that the spatial facilitation observed between group III and IV muscle afferents and the other afferents indicate a convergence from group III and IV muscle afferents and the other afferents on common interneurones in segmental flexor reflex pathways. Pathologic complete response (pCR) has been suggested as a surrogate prognostic indicator in breast cancer patients treated with neoadjuvant chemotherapy. Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3.

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We selected all studies in which a modification of the IC was tested to improve comprehension in low literacy populations. 3-D histo-radiographic comparison of surgical clearances of microcalcified lesions in breast localization biopsies. Terrestrial biological diversity is supported by solar energy captured by plants growing in soil. The average log2 rise was 4.5 for HAI antibody and 4.1 for neutralizing antibody. We acclimated crucian carp to 10, 15, 20 and 25 degrees C for 1 month, and investigated gill morphology, oxygen consumption and the critical oxygen concentration at the different temperatures. The proteasome is an essential mediator of the activation of pre-MPF during starfish oocyte maturation. Cases of tuberculosis (TB) in the United States have declined for 4 consecutive years, but cases among foreign-born persons account for an increasing percentage. Such information, described and evaluated in this article, provides important new insights into the etiology of carcinogenesis and how tumor growth, invasion and metastasis might be therapeutically arrested. On the factor structure of the Beck Depression Inventory-II: G is the key. EMI can arise from the normal functioning of electrical appliances or from alternating current leak.

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The first roentgenological manifestations of a silicosis caused during the period of dry drilling especially in ore metal mining, are frequently bilaterally increased shadows of the hilum without any worth mentioning findings in the parenchyma. In healthy subjects, 300 mg of sulpiride caused no alteration in time estimation and choice reaction movement time, whereas critical flicker fusion frequency was lower and choice-reaction decision time were prolonged under medication. Secondary nutritional and drug prevention of cardiovasculopathies. Cerebral dysfunction: clues to neurological disorders in children. Needle-knife fistulotomy versus standard method for cannulation of common bile duct: a randomized controlled trial.

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Indications for pancreatic resections for metastatic disease have not yet been defined to date, and few guidelines exist for the management of these lesions. The treatment of animals with oltipraz alone resulted in dose-related increases in the GST Ya, Yb1, Yc1, and Yc2 mRNA levels, whereas Yb2 mRNA levels were, minimally increased. Self-regulation of pir, a regulatory protein responsible for hyperinduction of pectate lyase in Erwinia chrysanthemi ultram brand discontinued EC16. Clues to the site of the enzyme defect resulted from studies with the immunosuppressive agent azathioprine, which normally causes uric acid concentrations to fall in blood and urine but was without effect in a Lesch-Nyhan patient. Initiation of CPB results in a moderate increase in intestinal microvascular permeability to protein and an increase in intestinal tissue water. Clinical outcome is significantly different according to the metastatic sites. Maximum phonation time, maximum phonation intensity, and rating scales of shunt voice, aspiration rate, and survival time.

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