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Skelaxin (Metaxalone)

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Skelaxin is a muscle relaxer. It provides relief from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness, and muscle spasms.

Other names for this medication:
Fenaplus, Flexura, Metadol, Metaxalone, Mobiswift, Skeltab

Similar Products:
Depakote, Biaxin, Asacol, Elocon, Nuvigil, Imodium, Panadol

Also known as: Metaxalone


{name} (metaxalone) is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain.

{name} is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.


Usual Adult Dose for Muscle Spasm:

800 mg orally 3 to 4 times a day.

Usual Pediatric Dose for Muscle Spasm:

>= 12 years: 800 mg orally 3 to 4 times a day.

Detailed Skelaxin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of metaxalone can be fatal.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Flammable: Keep away from fire or flame.

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Side effects

The most common side effects associated with Skelaxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Skelaxin if you are allergic to metaxalone, or if you have:

anemia (low red blood cells); severe kidney disease; or severe liver disease.

To make sure Skelaxin is safe for you, tell your doctor if you have liver or kidney disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether metaxalone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Skelaxin is not approved for use by anyone younger than 12 years old.

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Within the WHO MONICA Project, stroke has been recorded in 18 populations in 11 countries. In contrast to extremity sarcoma, postoperative radiation therapy (RT) has shown limited efficacy due to its limitations in achievable dose and coverage. The crucial point regarding non-toxic nodular goiter is the early diagnosis of neoplasm. It is concluded that the spatial facilitation observed between group III and IV muscle afferents and the other afferents indicate a convergence from group III and IV muscle afferents and the other afferents on common interneurones in segmental flexor reflex pathways. Pathologic complete response (pCR) has been suggested as a surrogate prognostic indicator in breast cancer patients treated with neoadjuvant chemotherapy. Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3.

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The first roentgenological manifestations of a silicosis caused during the period of dry drilling especially in ore metal mining, are frequently bilaterally increased shadows of the hilum without any worth mentioning findings in the parenchyma. In healthy subjects, 300 mg of sulpiride caused no alteration in time estimation and choice reaction movement time, whereas critical flicker fusion frequency was lower and choice-reaction decision time were prolonged under medication. Secondary nutritional and drug prevention of cardiovasculopathies. Cerebral dysfunction: clues to neurological disorders in children. Needle-knife fistulotomy versus standard method for cannulation of common bile duct: a randomized controlled trial.

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Indications for pancreatic resections for metastatic disease have not yet been defined to date, and few guidelines exist for the management of these lesions. The treatment of animals with oltipraz alone resulted in dose-related increases in the GST Ya, Yb1, Yc1, and Yc2 mRNA levels, whereas Yb2 mRNA levels were, minimally increased. Self-regulation of pir, a regulatory protein responsible for hyperinduction of pectate lyase in Erwinia chrysanthemi ultram brand discontinued EC16. Clues to the site of the enzyme defect resulted from studies with the immunosuppressive agent azathioprine, which normally causes uric acid concentrations to fall in blood and urine but was without effect in a Lesch-Nyhan patient. Initiation of CPB results in a moderate increase in intestinal microvascular permeability to protein and an increase in intestinal tissue water. Clinical outcome is significantly different according to the metastatic sites. Maximum phonation time, maximum phonation intensity, and rating scales of shunt voice, aspiration rate, and survival time.

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We demonstrate that alkyl coumarates and caffeates, which are the major components of Arabidopsis (Arabidopsis thaliana) root waxes, are present primarily in taproots. Thirty-four hips had had a high hip center before the index revision, and most patients had had a substantial limb-length discrepancy, with a mean of 1.6 centimeters of shortening on the side of the operation. A number of biological applications require comparison of large genome strings. Chondrotympanoplasty: a modified technique of cartilage graft tympanoplasty. Clinical oral health indicators emerged as significant predictors of perceived oral health status in the dentate although the explanatory power of these indicators on perception of oral health was low. Nevertheless, the exact interrelationship between reduced HC volume and HC-vmPFC connectivity deficits in the context of stress has yet to be established. However, Hill equations are highly nonlinearly parameterized functions, and parameters in these functions cannot be measured easily. Ovarian follicular lasix angiogenesis, the population of large follicles and ovulation were examined.

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