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Rebetol (Ribavirin)
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Rebetol

Rebetol is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses. Rebetol is incorporated into viral RNA, thereby inhibiting viral RNA synthesis, inducing viral genome mutations, and inhibiting normal viral replication.

Other names for this medication:
Copegus, Ribavin, Ribavirin, Virazide, Virazole

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Also known as: Ribavirin

Description

{name} (ribavirin) is an antiviral medication that is used to treat chronic hepatitis C.

{name} is not effective when used alone. This medicine must be used in combination with interferon alfa or peginterferon alfa.

{name} is sometimes given to people taking other antiviral medications to treat hepatitis C.

Dosage

Take Rebetol with food. The recommended dose and duration of Rebetol ranges between 800mg to 1400mg/day depending on how much the patient weighs and the medicines that are used in combination. - 800 mg/day: Take 2 Rebetol 200 mg tablets in the morning and 2 tablets in the evening. - 1000 mg/day: Take 2 Rebetol 200 mg tablets in the morning and 3 tablets in the evening. - 1200 mg/day: Take 3 Rebetol 200 mg tablets in the morning and 3 tablets in the evening. - 1400 mg/day: Take 3 Rebetol 200mg tablets in the morning and 4 tablets in the evening. Rebetol is prescribed in combination with other medications such as Sofusbuvir and Peginterferon Alfa 2a/2b for preventing Hepatitis C virus (HCV) cells from multiplying in your body. Treatment of HCV genotypes 1, 2, 3 and 4 is possible with Rebetol, however it is never used on its own.

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rebetol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Rebetol if you are allergic to ribavirin, or if you have:

a hemoglobin blood cell disorder such as sickle-cell anemia or thalassemia; autoimmune hepatitis; moderate to severe kidney disease; if you are also taking didanosine; or if you are pregnant, or if you are a man whose sex partner is pregnant.

When you take Rebetol in combination with other medications: There may be other reasons you should not take the combination treatment. Tell your doctor about all your medical conditions.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

a blood cell disorder such as anemia (low red blood cells); heart problems, high blood pressure, or heart attack; breathing problems; vision problems (you may need an eye exam before taking ribavirin); diabetes; human immunodeficiency virus (HIV or AIDS) or a weak immune system; depression, mental illness, thoughts of hurting yourself or others; a thyroid disorder; kidney disease; an organ transplant; liver problems other than hepatitis C; or treatment for hepatitis C that did not work well.

Both men and women taking Rebetol should use effective birth control to prevent pregnancy. Ribavirin can cause birth defects, miscarriage, or death to an unborn baby if the mother or father is using this medicine.

If you are a woman, do not take Rebetol if you are pregnant. You will need to have a negative pregnancy test before taking this medicine. You will also need pregnancy tests during treatment and for 6 months after your last dose. If you are a man, do not take Rebetol if your sex partner is pregnant. Both men and women should keep using effective birth control for at least 6 months after the last dose of ribavirin. Tell your doctor right away if a pregnancy occurs while either the mother or the father is taking this medicine. Your name may be listed on a pregnancy registry to track the effects of ribavirin on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Rebetol capsules are not approved for use by anyone younger than 3 years old.

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