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Optizole (Alprazolam)
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Optizole

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Optizole, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Optizole is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alfresh, Alprac, Alprasert, Alprax, Alprazolam, Alprosym, Alprowon, Alzam, Alzep, Alzex, Alzokam, Anxit, Apsolam, Aryalam, Ateez, Belfa, Besquil, Cooltime, Depsolam, Dizeral, Endolam, Enxolam, Fledore, Flumusa, Fluti, Mebasap, Nokzok, Nucalm, Omelam, Prazolam, Pronext, Propnix, Prosanti, Resto, Rozin, Samprex, Samrox, Tranisol, Trazopin, Xerodep, Zedep, Zolam, Zolar, Zolax, Zoloid, Zopain, Zopral

Similar Products:
Exelon, Coumadin, Zocor, Motrin, Aurogra, Revia, Altace

Also known as: Alprazolam

Description

Optizole is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Optizole is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Optizole if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Optizole or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Optizole. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Optizole. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Optizole dosage information

Side effects

The most common side effects associated with Optizole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Consequently, there is also considerable potential for cryptic female mate choice to operate on the basis of sperm karyotype. A considerable increase was noted in the content of sphingomye lin and phosphatidylcholine together with a marked drop in the content of phosphatidylethanolamine, phosphatidylinosite and phosphatidylserine. Effect of in-line intravenous filtration on the potency of potassium penicillin G. The quantification of planar scintigraphy using three dimensional modelling of organ shadows. They also showed that formation of the HS2 protein complex requires the integrity of the whole hairpin sequence. Selective shunting based on somatosensory evoked potential monitoring during carotid endarterectomy. Massive tissue eosinophilia appears to be related to the histological differentiation of the tumours in which it occurs, and in the cases in this series was associated with a favourable prognosis. The radiation-hydrodynamics code LATIS is used for the modeling. Immunohistochemistry for the presence of aromatic hydrocarbon receptor (AhR) was performed in another set of morula-stage embryos. We speculate that the higher frequency of fibrillin-1 gene intron 56 G-allele increases the risk of mitral valvar prolapse.

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Whilst TMA and TMNO are generally regarded as non-toxic substances, they are of clinical interest because of their potential to form the carcinogen N-nitrosodimethylamine. Monoclonal antibodies against all three leukocyte Fc gamma R classes stained placental villous macrophages. BM stroma cells, including the primitive pluripotent MSCs and MAPCs, are attractive targets for cell and gene therapy. Adsorption equilibrium of PAHs on activated carbon from the vegetable oil was successfully evaluated by the Langmuir and Freundlich isotherms. This was confirmed by the surgical outcome and by the follow-up of each patient. Effects of sodium fluoride on total serum protein levels and transaminase activity in rats. Serum and bronchoalveolar lavage fluid (BALF) pathogen specific IgG1, IgG2, IgE, and IgA responses were evaluated by ELISA. Serum erythropoietin levels, red cell folate and creatinine clearance were determined in subjects aged 65 years and over. Efficacy of ivermectin against experimental and natural infections of Gasterophilus spp in ponies. The concentrations of 3 beta-hydroxy-5-cholestenoic acid, 3 beta,7 alpha-dihydroxy-5-cholestenoic acid, and 7 alpha-hydroxy-3-oxo-4-cholestenoic acid were determined in plasma from patients treated with cholestyramine or subjected to resection of the ileum or colon.

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In contrast, it has been stated that Hh signaling in the limb bud ectoderm cannot occur because components of the Hh signaling pathway and Hh target genes have not been found in this tissue. We report also that a second superantigen, enterotoxin B, has similar regulatory properties. The finding that more patients with syndesmophytes had reduced bone density than those without suggests that bone growth and bone loss occur in parallel, and the role of inflammation in this process warrants further investigation. Here, we studied the molecular changes involved in the development of TPA-mediated MTX resistance in Chinese hamster ovary (CHO) cells. These include arthrodiastasis and the osteochondral autograft transfer procedure.

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It was observed that a structure-activity relationship could be derived for a subset of aldehydes that could react via the same chemical mechanism. Carotid artery imaging in the United kingdom: a postal questionnaire of current practice. The characteristics of the fluid were also compared with those of lymph and saliva. We also examine racial/ethnic disparities in the receipt of preventive services among enrollees in FFS or MCO plans. Results in fifteen patients with excellent bone formation were classified as grade one, in nine patients with good bone formation as grade two, and in four patients with scanty bone formation as grade three. Reverse transcription-polymerase chain reaction revealed upregulation of Notch1, Notch2, Jagged1, HES1 and HEY1 in both OSCC cell lines and biopsy specimens. We conclude that despite the tremendous shuffling of chromosomes during the course of mammalian evolution, the pattern of genomic imbalances is conserved between BRCA1-associated mammary gland tumors in mice and humans. Catalase-positive rods of different dimensions, which frequently appeared crystalline by light microscopy, were found to be concentrated along with microbodies and cytoplasmic enzyme in the cells of the striated and extralobular excretory ducts of mouse salivary glands. Hypertension was diagnosed in 153, and elevated blood pressure, not confirmed as hypertension, was recorded in an additional 226.

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Multiple sodium-dependent nucleoside transport systems in bovine renal brush-border membrane vesicles. We conclude that the N-acetylglucosaminylphosphotransferase in the mutant fibroblasts has normal catalytic activity but is defective in the ability to recognize lysosomal enzymes as specific substrates for phosphorylation. Clinically relevant, endoscopically confirmed UGIB is a rare event in the ICU setting and tends to occur in severely ill patients. Intraspinal abnormalities and congenital spine deformities: a radiographic and MRI study. sculpturatus, is a native of Arizona and adjacent parts of New Mexico in the United States, and Baja California and Sonora in Mexico. We found that patients with elevated sCA125 levels had significantly more adverse prognostic factors at diagnosis, lower CR rates, higher relapse rates and worse survival. Prolactin-I125 accumulation in the mammary gland occurred at a constant rate. However, the rate and severity of posttransplant rejection was significantly higher in the group with continuous flow devices. Different lifestyle factors seem to be associated with the risk for atopic diseases and some studies suggest that stress increases the risk of allergic sensitization, asthma and atopic eczema. Recent experimental research in man and animals has suggested that it may be possible to explore the function of these organs by studying the vestibule-sternocleidomastoid reflex induced by high intensity clicks.

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Differentiation of membrane channel models based on fluctuation (or noise) analysis is discussed. Adenosine is currently being investigated as a possible mediator of a homeostatic sleep need. False serum calcitonin high levels using a non-competitive two-site IRMA. Wise and sustainable uses of water resources are essential for an effective river-basin-management planning. Arg(311) is not conserved in B1R, and complementary mutations in B2R and B1R showed that this residue, together with previously identified serines and threonines, acts to attenuate the coupling efficacy of B2R. It was established that localized exposure of an inflammatory focus to laser radiation causes, besides the well-known effect on biochemical activity, structural photophysical reorganization of the liquid crystalline complexes not only in the irradiated tissues but also in parts of the organism situated at a distance from the exposed area. Nine Nigerian children, with infantile spasms, 4 boys and 5 girls age 2.5-15 months, were treated with high doses of vitamin B6.

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In crossed affino-immunoelectrophoresis pure haptoglobin or that present in serum moved in the shape of either non-retarded or weakly-, or strongly-retarded fractions, related to varying Con A concentrations included into the first dimension gel. In Experiment 2, older drivers were assigned to one of three cohorts: active simulator training, passive classroom training, or no training. Forced recruitment of GAL4-CBP fusion proteins to the K18 promoter results in a greater stimulation of its activity in non-tumorigenic than in tumorigenic cells. Furthermore, we found that the general model fit the data better than the simpler covarion models in the majority of the cases, highlighting the complexity in modeling the covarion process. Greater absolute and relative postoperative hemoglobin values were observed in Group A immediately postoperative, on Day 5, and on Day 6.

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In the higher dose ranges, the major cause of death was acute cardio-pulmonary toxicity. Lesions of the extensor muscles of the knee caused by meniscus injury. Of the three approaches, only long-term withdrawal studies are capable of unambiguously revealing the net effects of caffeine. A protective device deep to the popliteus may protect against popliteal injury. They stimulate the immune system, have anti-neoplastic properties and participate in cell signalling and proliferation regulation. These factors span a range of physical, chemical, and biological variables that can impact signal production, stability and distribution. This study was to compare the clinical features, short-term efficacy and survival of T-LBL patients with or without myeloid antigen expression so as to evaluate its prognostic significance. These compounds are derivatives of galactocerebrosides bearing a malonate side chain in positions 2 and 3 of the galactose moiety. In contrast, siderophore-mediated iron acquisition by saprophytic bacteria has received relatively little attention. In decerebrate unanaesthetised cats the cardiovascular effects of raising the pressure in a blind sac preparation of a carotid sinus on one side were examined at rest and during sustained contractions of hind-limb muscles.

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Effect of the lengthening of the protocol on the reliability of muscle fatigue indicators. However, in some cases, the circulation decreased or remained unchanged, which was accompanied by pronounced hypotension. Transparent physical space induced escape and inhibited jumping. This study shows that nongastric marginal zone lymphomas are characterized by a high prevalence of HCV infection. The isolated phage-displaying peptide, SMSIASPYIALE (named peptide PIII), was obtained after four rounds of selection cardizem drug guide , showing a tendency to preferentially bind to GC9811-P cells compared with a panel of other gastric cancer cell lines, and preferentially accumulate in peritoneal metastasis tumor tissue in comparison with control organs, peritoneum, liver, pancreas, spleen, lung, and kidney. Thalamocortical specificity and the synthesis of sensory cortical receptive fields. Nucleotide and amino acid sequences of pulmonary surfactant protein SP 18 and evidence for cooperation between SP 18 and SP 28-36 in surfactant lipid adsorption. In addition, iPKS functions involved in fungal spore pigment biosynthesis were analyzed together with polyketide-shortening enzymes that convert products of PKSs to shorter ketides by hydrolytic C-C bond cleavage. This is very important for selection of the breast cancer treatment methods.

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Self-assembly of colloidal spheres confined within cells of different shapes formed with two slides under capillary forces are studied. The double-layer model, optimized for low concentrations, was tested against sorption experiments of carbonate on goethite at higher concentration by Villalobos and Leckie, and reasonable agreement was found. We found that porcine pancreas extracts (PX) significantly decreased blood-ionized calcium in Balb/c mice. The present case suggests that adult influenza A virus-associated encephalitis/encephalopathy or ANE can occur during winter influenza epidemics. In assessing possible in vitro interference from bilirubin on analytical methods, different results are to be expected from using either unconjugated (uB) or conjugated (cB) bilirubin as test materials, because of their different solubilities. These results confirm that decreased folate levels are capable of inducing DNA hypomethylation in colon cells and particularly in the region of the p53 gene, suggesting that a more optimal folate status in vivo may normalize any DNA hypomethylation, offering potential protective effects against carcinogenesis. Hepatocytes in vivo have a potential for liver regeneration, but it has been very difficult to reconstruct hepatic organoids in vitro.

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Although studies have suggested that comorbid medical illness can affect the outcome of patients with depression, little is known about whether medical illness comorbidity affects treatment outcome in patients with anxiety. Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation. Music training improves pitch perception in prelingually deafened children with cochlear implants. A comparison of the daily energy needs of the normal and dwarf broiler breeder hen. The velocity of blood flow was measured by an ultrasonic Doppler flowmeter. We hypothesized that treatment with pulse methylprednisolone therapy (PMT), alternate-day corticosteroids, and cyclosphosphamide or cyclosporine would decrease proteinuria in patients with familial FSGS. A review of the medical records including sex, age, laterality, etiology, therapy, severity of paralysis according to House-Brackman (HB) six-point grading scale, duration, and degree of recovery. Staggered local density of states around the vortex in underdoped cuprates. Used effectively even these screening tests require the interpreting physician to have an understanding of the typical features of cataplexy. Compound 4 exhibited an anomalously high complex formation ability among these compounds, due to the strong electron-withdrawing effect of the phosphonium cation moiety.

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