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Nuvigil (Armodafinil)
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Nuvigil

Nuvigil 150mg is a drug that help individuals to stay awake. The medication is widely used for treating sleep apnea, narcolepsy and other sleep related problems. This medication contains active ingredient called as Nuvigil. It is approved by the US Food and Drug Administration in 2007 June. This is a prescription only medication that has a biological half-life of twelve to fifteen hours. This wakefulness promoting agent is available to the patients in an oral form.

Other names for this medication:
Armod, Armodafinil, Biryth, Waklert

Similar Products:
Zebeta, Danocrine, Buspar, Risperdal, Tofranil, Furadantin, Revia, Maxolon, Bactrim, Ticlid

Also known as: Armodafinil

Description

Nuvigil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder).

This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Nuvigil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder.

It is not known how Nuvigil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.

Dosage

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Nuvigil is usually given for up to 12 weeks. Follow your doctor's instructions.

Nuvigil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.

If you are taking Nuvigil to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction.

Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and Nuvigil may be necessary to best treat your condition.

Nuvigil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder.

Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking Nuvigil.

Overdose

When a person takes too much Nuvigil, overdose symptoms may include unusual bruising or bleeding, nausea, diarrhea, and chest pain. Specific effects will be based on certain factors. If the Nuvigil overdose was recent, healthcare providers may give certain medicines, place a tube in the stomach to pump the stomach, or treat the symptoms that occur as a result of the overdose.

Storage

Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Nuvigil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Nuvigil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Nuvigil may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid other dangerous activity until you know how this medication will affect your level of wakefulness.

Avoid drinking alcohol while taking Nuvigil.

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The LeETR4 phosphorylation state closely paralleled ripening progress, suggesting that the phosphorylation state of receptors is implicated in ethylene signal output in tomato fruits. Using an isolated abdominal nerve cord preparation, we have analyzed the change in LG activity by applying additional sensory stimulation after different periods following habituation to characterize the retention of LG habituation. Prestimulus EEG microstates influence visual event-related potential microstates in field maps with 47 channels. To explore the miRNA differential expression profiles of hyperplastic scar and normal skin so as to further elucidate the pathogenesis of hyperplastic scar and search for new therapeutic targets. This means that low levels of psychological resources do not exacerbate the effect of functional limitation on disability in community-dwelling older persons. Odds ratios for very preterm birth by gestational age and by pregnancy complications leading to preterm delivery associated with a history of induced abortion.

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To explore the expression of heat shock protein 27 (HSP27) in the CA1 area of hippocampus in temporal lobe epilepsy (TLE) so as to elucidate the relationship between HSP27 and epileptogenesis of TLE. Some similarities to the present state of allied health education and cautionary signs are noted. Variables affecting splitting of the second heart sound in normal children. Here we show the utility of an (19)F-labeled methotrexate (FMTX) with (19)F magnetic resonance to differentiate between sensitive and resistant tumors in vivo and thus predict therapeutic response. The MG-QOL15-J is anticipated to be a valuable clinical measure of QOL in Japanese patients with MG. Efforts towards improving risk-stratification of stage II colorectal cancer patients and optimising therapy in patients with advanced disease, have focused on molecular and genetic markers. New thrombolytic drugs are unlikely to lead to further major reductions in fatality, and demonstrating small differences from existing compounds would require even larger trials to establish mortality benefits. Endogenous PHD2mRNA and PHD3mRNA were hypoxia-inducible, whereas expression of PHD1mRNA and FIH-1mRNA was oxygen independent. Evaluation of a home-based voluntary counselling and testing intervention in rural Uganda. These alterations appear to be more than mere chance associations, ie, they seem to be intimately involved with the histiocytic proliferation.

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Previously, we have reported that proteolipid protein (PLP) peptide 91-110 can induce experimental autoimmune encephalomyelitis (EAE) in HLA-DR3 transgenic (tg) mice. In such a way, expectancy of the anesthetic effect was directed only toward the part on which the placebo cream was applied. In recent years, however, endocannabinoid signaling specificity began to emerge, in particular, due to the production of genetically engineered mice lacking key enzymes in endocannabinoid synthesis or degradation, together with the development of selective inhibitors of AEA or 2-AG catabolic enzymes. The qualitative data obtained from the fieldwork phase were analyzed to refine and extend the working definition. The order gives unprecedented authority to government officials to intrude at will in controlling academic research that depends on federal support. The formulation consisted of drum dried waxy maize starch, Carbopol 974P, and ciprofloxacin in a ratio of 90.5/5/3 (w/w/w). More than five hundred medical doctors have now been qualified as Japanese board of clinical genetics.

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This method would appear particularly useful for obturation of large palatal defects that have failed to heal after attempts at surgical closure and is an alternative treatment for debilitated cats which may not be candidates for longer surgical procedures. Aim of this study was to analyze the prevalence and antimicrobial susceptibility of rods of the species Acinetobacter baumannii and Pseudomonas aeruginosa, belonging to multidrug-resistant alert pathogens. We review the current indications for intervention in fetuses diagnosed with congenital lung lesions, congenital diaphragmatic hernia, sacrococcygeal teratoma, and obstructing airway lesions. Is surgical-tocolytic prevention and therapy of cervical insufficiency justified without prenatal diagnostic care?. A range of models were tested and were evaluated based on their predictive performance. In the perikarya of striatal neurons however, the highest levels of NR2B immunoreactivity were detected at PND 14 and adult striatal neurons. Correlation coefficients were computed between average response waveforms recorded from different brain regions of trained cats, before and after a specific stimulus acquired cue value.

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Patients with vertigo tended to have hearing fluctuation, compared with the patients without vertigo. It is hypothesized that intrarenal B cells enhance immunological responses and exaggerate the local immune response to persisting autoimmune damage in the tubulointerstitium. This CENP-E-dependent BubR1 autophosphorylation at unattached kinetochores is important for a full-strength mitotic checkpoint to prevent single chromosome loss. Non-isotropic contributions to 1H MR spectra from human skeletal muscle in vivo have recently been observed in the 0- to 5-ppm region. In this study, the concentrations of ciprofloxacin in serum and lung tissue were determined by HPLC in patients undergoing lung surgery.

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Lymphocyte homing is initiated by their tethering to and rolling on the high endothelium and is followed by extravasation into the lymph nodes. The objective of this study is to compare the frequency of abdominal incisional hernias between two continuous suture techniques with different, slowly absorbable monofilament materials and an interrupted suture using an absorbable braided suture material at one year postoperatively. Prior investigations suggest that the response of the renal PBR to stress occurs independently of the hypothalamo-pituitary-adrenal (HPA) axis and sympathetic nervous system. Therapy of diffuse suppurative peritonitis with continuous peritoneal lavage. Dendritic cells (DCs) are the most effective antigen-presenting cells. We report a case of actinic cheilitis treated with PDT using ALA, with satisfactory outcome in both clinical and pathological aspects. Primary prostate signet ring cell carcinoma is a low-differentiated adenocarcinoma of a special histologic type, which arises from the epithelial cells of the prostate acinus.

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The effect of point of reference on the association between self-rated health and mortality. The multi-bracket appliance was worn for 3 months when the wound contraction became mild. Guidelines are developed in a context of budget constraint, and the general aim of the program is to promote the more efficient use of available health resources. ultram renal dosing We successfully explain this phenomenon by a QM/MM type of excitation energy calculation. The preoperative estimated weight of the prostate ranged from 35 g to 102 g, averaging 52 g. When considered alongside epidemiological knowledge elsewhere in medicine, psychiatric epidemiology has indisputably proved to be a powerful tool.

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Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and beta-amyloid peptide 1-42. Selective administration of selenomethionine 75Se in pancreatic scanning. Homologous recombination safeguards genome integrity, but it can also cause genome instability of important consequences for cell proliferation and organism development. Caffeine was detected in the range of 25.6-108 mg per capsule or tablet. The results show clearly that it is the apical part of the cochlea that generates the 500 Hz FFR, but the area of the basilar membrane that contributes is rather broad. SCAMP1 and SCAMP2 can be co-immunoprecipitated following detergent solubilization, using antibodies that specifically react with only one of the variants. A novel and straightforward total synthesis of cepabactin and its iron (III) complex is described. A substantial number of patients start their first-line antiretroviral therapy at an advanced stage of an HIV-1 infection. A short course of granulocyte-colony-stimulating factor to accelerate wound repair in patients undergoing surgery for sacrococcygeal pilonidal cyst: proof of concept. We investigated a paddy-field district subject to collective crop rotation and quantified the annual nutrient load of effluent from the district in three consecutive years.

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