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Compazine (Prochlorperazine)

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Compazine is an anti-sickness medicine. It can help stop you feeling or being sick (nausea or vomiting). You can take Compazine to treat: morning sickness. Compazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety.

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

Similar Products:
Anafranil, Sporanox, Glucophage, Valtrex, Robaxin, Prandin, Aldara

Also known as: Prochlorperazine


Prochlorperazine suppository is used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain prochlorperazine. It may not be specific to Compazine. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 20 to 30 minutes or run cold water over it before removing the wrapper. Remove the wrapper and moisten the suppository with cool water. Lie down on your side and use your finger to push the suppository well up into the rectum. Make sure to wash your hands with soap and water before and after using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppository): For severe nausea and vomiting: Adults—25 milligrams (mg) 2 times a day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Compazine dosage information

Side effects

The most common side effects associated with Compazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prochlorperazine suppository in children 2 years of age and older or weighing 9 kilograms (kg) (20 pounds (lbs)) and over. Use in children younger than 2 years of age or weighing under 9 kg (20 lbs) is not recommended.

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Prolonged inhibition of NO synthesis increases urinary excretion of ET-1 and albumin without having any effect on plasma ET-1 levels. In vivo, retinal overexpression of ephrinA2 leads to topographic targeting errors of temporal axons. This is a retrospective study of 121 patients who had a baseline FDG PET/CT scan for oncologic staging. Theoretical calculations indicate that the high reverse barrier to C-D recombination and the facile desorption of CD(2)O make photocatalytic methanol dissociation on TiO(2)(110) proceed efficiently. The authors examine the chronic effects of exogenous nitrosothiol therapy and demonstrate that the commonly used antioxidant N-acetylcysteine (NAC) induces pulmonary arterial hypertension in mice. Histologically, cysts were often degenerate and associated with mild to marked inflammation, and amyloidosis was noted in one animal. To collate the research reported on the various hazards associated with the ultrasonic dental scaler and discuss possible future research areas. Regulation of K-Cl cotransport during reticulocyte maturation and erythrocyte aging in normal and sickle erythrocytes. While the previous review of CNS-IRIS in the HIV-infected patient on highly active antiretroviral therapy (Part 1) dealt with an overview of the biology, pathology, and neurologic presentation of this condition and a discussion of the atypical imaging findings in PML-IRIS and cryptococcal meningitis-IRIS due to the robust inflammatory response, the current review (Part 2) discusses the imaging findings in other commonly encountered organisms seen in association with CNS-IRIS, namely, VZV, CMV, HIV, Candida organisms, Mycobacterium tuberculosis, and Toxoplasma gondii. Positive skin tests in late reactions to radiographic contrast media.

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She had elevated levels of parathyroid hormone (PTH) as a result of secondary hyperparathyroidism with advanced renal failure. The inhibitory effects of AMD occurred at lower concentrations of iodide than those seen in the NaI-treated cells. This difference may be due to the conservative sexual behavior in Turkey. Keratinocyte growth factor receptor (KGFR), also known as fibroblast growth factor receptor (FGFR)2 IIIb, is located in many types of epithelial cells and is activated by four known ligands (FGF-1, FGF-3, FGF-7 (also known as KGF) and FGF-10) that are predominantly synthesized by mesenchymal cells. In a two-hybrid screen with a vertebrate Pc homolog as a target, we identify the human RING1 protein as interacting with Pc. To evaluate the short-term effectiveness of local laminectomy and interlaminar lumbar instrumented fusion (ILIF) through a small incision for lumbar spinal stenosis. The complaints on admission were leg edema and left chest pain in the first patient, and a pyrexia and dyspnea in the second patient. It allows for the reconstruction of sound field without the use of any matrix inversion. In addition, the protein levels and kinase activities of cyclin D1, Cdk4, and cyclin E were higher in poorly differentiated HCC and advanced HCC.

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Calcium homeostasis in crustacea: the evolving role of branchial, renal, digestive and hypodermal epithelia. In some cases, the influence of wash-off conditions should be clarified to propose narrower parameter intervals for practical assessments. The charts of patients treated with gentamicin perfusion via the MicroWick between the years 1998 and 2000 were reviewed. Although some implant fixtures may need to be trephined and the site grafted and retreated, this is a long process and may have an unpredictable outcome. Effects of age on citrate metabolism in bone and on the distribution of skeletal fluoride. These increases in the GST mRNA levels were consistent with those in the immunochemically detectable GST protein levels. fumigatus, a severe lesion in bronchioli or alveoli is induced by the proteinase producing strains, and that these strains are more virulent than the proteinase nonproducing strains.

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Evaluation of postoperative IOP control and complications with a modified surgical procedure. Plasma glucose and insulin concentrations were measured in blood samples collected before and for up to 8 hours after glucose or insulin administration. Patient accounts management: how a small hospital does it successfully. Prevailing attitudes seem to indicate a need for this specialty in chiropractic, but the chiropractic radiological consultant is not widely used. PR concentration in the nuclei of glandular cells of endometrium in CC group was significantly lower than that in the control group. In this study we address the role of the cell body cytoskeleton in these structural changes. Phototoxicity of peptidoconjugates modulated by a single amino acid. Substrate L1-triggered neuritogenesis and neuroprotection depended on distinct but also overlapping signal transduction pathways and on the expression of L1 at the neuronal cell surface. Clustering of T cell ligands on artificial APC membranes influences T cell activation and protein kinase C theta translocation to the T cell plasma membrane. The father, like the mother, can transmit genetic defects to his offspring that are detrimental for normal development and a healthy life.

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Prospective in-patient cohort study of moves between levels of therapeutic security: the DUNDRUM-1 triage security, DUNDRUM-3 programme completion and DUNDRUM-4 recovery scales and the HCR-20. In 4 additional cows, the concentration of Pi was measured in blood samples obtained simultaneously by jugular and coccygeal venipuncture into heparinized tubes before the morning feeding and 2, 4, and 6 hours after the feeding. Matrix metalloproteinases (MMPs) and their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), appear to be involved in aneurysm formation, as evidenced by increased aortic tissue MMP activity and plasma MMP levels in patients with AAA. In addition, the expression level of endothelial sulfated sialyl Lewis x epitopes and the number of mucosal eosinophils correlated with the severity of the inflammation, and decreased in specimens taken 9 months postoperatively compared with intraoperative samples, especially in patients with intranasal corticosteroid treatment. Elongation factor-1 alpha (EF-1 alpha) is an evolutionarily highly conserved universal cofactor of protein synthesis in all living cells.

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A rare case of arteriodigestive fistula: double communication between the aorta, the common iliac artery and the jejunum. Mice of the RIII and C57BL strains were treated with rabbit antiserum to thymus (ATS), and cells of their lymph nodes were analyzed serologi-cally at intervals after treatment. We observed that lens cells expressing the HPV18 transgene are more sensitive to wild-type human p53 action than normal lens cells. These differences indicate that the diameter of milk fat globules increases in mature milk. In this article, Dr Wineman discusses assessment of colorectal cancer risk and the advantages and disadvantages of the fecal occult blood test, flexible sigmoidoscopy, double-contrast barium enema, and colonoscopy. More concentration occurred among secular not-for-profit hospitals than among for-profit hospitals. During radiosurgery, a single high dose of ionizing radiation is delivered with exquisite precision to a radiographically defined intracranial target. Action of pronase and neuraminidase on the electrophoretic mobility of erythrocytes from normal cats and those with spontaneous tumours. The new 6beta,14beta-ethenomorphinans did not show affinity for any of the opioid receptors, in accordance with the inactivity earlier found in in vivo experiments.

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The paleogeographical, ecological, and epidemiological interest of this parasite is laid stress on. Disclosing conflicts of interest involving clinicians who prepare therapeutic guidelines. The autoantibody response was similar in both spontaneous and drug-related disease. We offer a complete and unified survey of one-dimensional shaped pupil designs, some of which have been published in our previous papers. Numerical models of parabolic on-axis and off-axis mirrors with surface imperfections are used to explore the accuracy of the procedure. Separation dilantin 150 mg of polypeptides by isoelectric point focusing in electrospray-friendly solution using a multiple-junction capillary fractionator. Effect of succinylsulfathiazole on the urinary excretion of folic acid by the rabbit. The fourth costal cartilage was resected and the left internal mammary artery was harvested under direct visualization. Several clinical parameters help predict the outcomes of men with PSA elevation after radical prostatectomy.

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Moreover, the inorganic phosphate peak was observed to be shifted downfield 70 Hz from the location seen in normal muscle. A symptomatic cipro dosage in dogs empty sella developed in a female patient undergoing bromocriptine therapy for microprolactinoma. To investigate the significance of telomerase activity in urine in the diagnosis and recurrence surveillance of urothelial carcinoma. Autoantibodies or clinical signs of inflammation were not found in these cases. This value showed that there was no difference between predicted and experimentally observed drug release profile.

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To compare functional results after surgery for macular pucker either with or without indocyanine-green staining of the internal limiting membrane (ILM) and to evaluate the ultrastructure of the tissue removed. nuclear disruption, protein synthesis and particle formation with the mutant 43-.30-.46-. Clinical features evoked salicylism despite low serum salicylate level: 178 mg/l. The H-reflex was unobtainable from either limb in two patients with advanced disease and loss of all sensory modalities. We conclude that, although pdx-1 is a key regulator of beta cell specific genes, it does not appear to play a central role in the up-regulation of islet cell function during pregnancy. In the absence of structural data, tissue segmentation based on DTI data provides an alternative means to obtain brain tissue segmentation.

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Cryopreservation in single-dose aliquots allows multiple DC vaccine doses to be manufactured from a single apheresis product. Development and properties of stereociliary link types in hair cells of the mouse cochlea. We describe a 58-year-old woman who presented with bilateral ophthalmoplegia, exophthalmos, and headache and was found to have retrograde internal jugular vein flow secondary to a high-grade obstruction of the ipsilateral brachiocephalic vein from a previous hemodialysis catheter placement. The development and optimization of crystallization processes requires screening of numerous solvent systems for which the solubility of the compound of interest has to be measured as a function of temperature and solvent composition. This model offered the possibility of comparing the capacity of an immunogenic epitope to stimulate a unique population of T-cell precursors depending on the lifespan of its presentation at the cell surface.

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The first group of compounds to disappear with increased sediment depth is pyrophosphate, followed by a steady decline of the different ester compounds. Internal multiple-scattering hole-enhanced Raman spectroscopy: improved backscattering Fourier transform Raman sampling in pharmaceutical tablets utilizing cylindrical-conical holes. Clinical studies on changes of water-electrolyte metabolism of the brain in experimental brain edema and the therapeutic effect of dexamethasone. On the basis of our previous demonstration of a structural and functional relation between PKAI and epidermal growth factor receptor, we have performed a double blockade of these pathways using HYB 165 in combination with monoclonal antibody (MAb) C225, an anti-epidermal growth factor receptor chimeric MAb. Phosphate exposure during the late 1-cell and early 2-cell stages induces a time-specific decrease in cyclin B and cdc25B mRNAs in AKR/N mouse embryos in vitro. Hepatitis C virus envelope glycoproteins and potential for vaccine development.

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Several trials of anti-manic agents in children were recently conducted and regulatory reviews of the data have become available. Skin dose and dose-area product values in patients undergoing intracoronary brachytherapy. Prolonged exercise training can, at least partly, reverse the mitochondrial impairments associated with the longstanding diabetic state. Thirty-six children showed an AFP level between 10,000 and 100,000 ng/mL, and 12 patients had values of greater than 100,000 ng/mL. Enzymatic microdetermination of oxygen for the control of oxidation in aqueous solutions. THE REGULAR FALL MEETING OF THE EXECUTIVE COMMITTEE OF THE COUNCIL. A computer based index for the prediction of operative survival in patients with cirrhosis and portal hypertension. Elevated serum CA19-9 level in diabetic patients may indicate further investigations of glycemic control, pancreatic beta cell function, and total cholesterol level.

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The most potent lysin identified to date is PlyC, an enzyme assembled from two components (PlyCA and PlyCB) that is specific for streptococcal species. The adhesion of ICAM-MPIO to endothelial cells was quantified by optical imaging and MRI. Only beta(1)-adrenoceptor stimulation produced significant CaM kinase II-related Thr17 phosphorylation, troponin I phosphorylation and activation of phosphorylase a. The method allowed HbO2Sat determinations in the whole range of arterioles, venules, and capillaries. Biokinetic steroid synthesis from labeled acetate and cholesterol in rat liver, cozaar 25 mg precio kidney and epididymal adipose tissue in vitro.

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The issue of therapeutical strategy is controversial, considering the options and limitations of resections of the anterior commissural tumors, within the conception of oncological radicalism. In situ FTIR reflection spectroscopy of molecule probe studies of enhanced IR adsorbtion and response rate to potential on Pd nanoparticles confined. This novel cell group likely serves as a relay or integration point for communicating photic phase-resetting information to the rhythmic cells of the SCN. Similarly, this IL-1beta- and TNF-alpha-induced formation of active 11beta-hydroxy glucocorticosteroids from inert 11-keto glucocorticosteroids by the 11beta-OHSD1 was shown in the Kiki cell line that expresses the stably transfected bacterial beta-galactosidase gene under the control of a glucocorticosteroids response element. We explored interactions on a multiplicative scale conducting a population-based case-control and a case-only study on 103 incident PCa patients and 132 unrelated controls. Crystal structure analysis at 2.6 A resolution revealed conformational changes within the interface of both domains compared with the structure of the isolated molecules. Effects on collateral behaviors (i.e., talking out to turn) were also assessed.

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Bertical distribution of optic nerve fiber terminations in the frog optic tectum. Using antisense morpholinos, we demonstrated that Bgn required Chordin to induce double axes in Xenopus. Three hundred eighteen patients with extensive SCLC (ESCLC) and 421 patients with limited SCLC (LSCLC) participated in four phase II or III trials. Determination of mannose-6-phosphate in pharmaceutical intermediates by high performance ion-exchange how many mg of motrin can a child take chromatography-electrochemical detection. The results also demonstrated that there was a paradoxical positive response in the central retina of cCSNB patients, as compared to the negative full-field ERGs in the same subjects. Fetal myoblast clones contribute to both fast and slow fibres in developing rat muscle. Isoniazid-induced expression of this transcriptional signature was abolished in dormant bacilli which had acquired phenotypic tolerance to isoniazid, regardless of the specific conditions responsible for the induction of the dormancy phenotype. Attitudes among surgeons towards live-donor nephrectomy: a European update.

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