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Carisoma (Carisoprodol)

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Carisoprodol, marketed under the brand name Soma among others, is a prescription drug marketed since 1959. It is a centrally acting skeletal muscle relaxant of the carbamate class and produces all the effects associated with barbiturates. It is a prodrug and is both structurally and pharmacologically related to meprobamate. The major metabolic pathway of Carisoma involves its conversion to meprobamate.

Other names for this medication:
Aciprodol, Carisol, Carisoma, Carisoprodol, Emflam, Somaflam, Soprodal, Vanadom

Similar Products:
Moduretic, Valtrex, Zantac, Avana, Effexor, Zetia, Allegra, Kamagra, Atarax

Also known as: Carisoprodol


Carisoma is a muscle relaxant that is prescribed after an injury makes muscles tense or lock up. The generic term for this drug is carisoprodol, and it may come in a pill compounded with aspirin, codeine or caffeine.

Unfortunately, this drug has become a frequently-abused drug. It is a drug that also creates a tolerance in the user, meaning that more and more of the drug must be abused to get the effect the drug user intended. It can also result in addiction. More than two million people in the US have abused Carisoma at some point in their lives.

When abused, Carisoma creates pain relief, sedation, sleepiness and muscle relaxation. In the body, the drug breaks down in part to form meprobamate, itself a drug that is sold to reduce anxiety. The brand names of meprobamate are Miltown and Equanil.


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take each dose with a full glass of water.

Do not stop using carisoprodol suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine. Carisoma is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures. Follow your doctor's instructions.


Overdosage of Carisoma commonly produces CNS depression. Death, coma, respiratory depression, hypotension, seizures, delirium, hallucinations, dystonic reactions, nystagmus, blurred vision, mydriasis, euphoria, muscular incoordination, rigidity, and/or headache have been reported with Carisoma overdosage. Serotonin syndrome has been reported with carisoprodol intoxication. Many of the carisoprodol overdoses have occurred in the setting of multiple drug overdoses (including drugs of abuse, illegal drugs, and alcohol). The effects of an overdose of carisoprodol and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants) can be additive even when one of the drugs has been taken in the recommended dosage. Fatal accidental and non-accidental overdoses of Carisoma have been reported alone or in combination with CNS depressants.


Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Carisoma is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Carisoma are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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As demonstrated in a recent CASPR experiment, improvement can be quite reliably achieved when the initial models are sufficiently close to the native basin (e.g., 3-4 A C(alpha) RMSD). Evidence for a model of exocytosis that involves calcium-activated channels. Therefore, the 3alpha-HSD activity of RoDH2 was exclusively oxidative. The present study evaluated the effects of morphine treatments on elevated plus maze test parameters, oxidative stress markers and Hsp70 expression in normal and stressed rats. The fragmentation of the reintroduction literature remains an obstacle. However, it should be noted that there were occasions that acute microbial toxicity was observed even from the treated water samples, some of which showed complete removal of the parent compound. To establish whether an array of effectors was required for Rap-induced cell adhesion and spreading, and to find new components involved in Rap-signal transduction, we performed a small-scale siRNA screen in A549 lung epithelial cells. A decade-long telemedicine screening program for diabetic retinopathy in the north-east of Italy.

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How WNKs stimulate endocytosis of ROMK1 and how mutations of WNK4 increase the endocytosis are unknown. The former were represented by the plasma disappearance curves of iv injected radiolabeled T3. Acute liver failure: definition, etiology, clinical picture and prognosis. Percutaneous needle fasciotomy is a minimally invasive treatment modality for Dupuytren disease. Thus, the aim of research is to study the morphological futures of skin regeneration after the chemical burn applying chitosan membranes. There are more than 100 polymorphisms identified in the human MOP (OPRM1) gene.

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Descriptive study using a structured questionnaire and convenience sampling. The results indicated that the intervention improved attitudes toward hypnosis, relative to a control intervention, and the improvements remained stable at 3-month follow-up. Uncommon aetiologies of chylothorax: superior vena cava syndrome and thoracic aortic aneurysm. Such processing is, to our knowledge, hitherto unknown for peptidergic neurons. These results provide the bases to pursue the study of the interaction between NEI and the HPT axis.

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Volatile components of flavored yogurt preserved at 5 degrees C in the dark for 0 day, 3 days and 10 days were recovered by simultaneous distillation extraction (SDE) and headspace (HS) procedures. This study investigates the belief and attitude regarding preference toward CAM use among the Malaysian population by using a questionnaire-based, cross-sectional study. The underlying causes of their failure in personal care are described in intrapersonal, interpersonal, and environmental dimensions. The value of each indicator is scaled relative to a reference state, i.e., a predicted value assessed by each expert for a hypothetical undisturbed or sustainably managed ecosystem. SDS-PAGE for purified mucin showed several high-molecular-weight bands for the HIV-negative group and prominently stained single bands on the stacking gel with faintly periodic acid Schiff-positive glycoprotein bands observed in some cases in the running gel for the HIV-positive mucins.

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We have studied the detection of apple scar skin, dapple apple, and pear rusty skin viroids in nucleic acid extracts of infected pome fruit tissues by reverse transcription-polymerase chain reaction (RT-PCR) with viroid cDNA-specific primers. The clinical features of symptoms, endoscopic findings and risk factors of gastropathy varied significantly between the elderly and the non-elderly. Toxicology of aflatoxin B1, warfarin, and cadmium in young pigs: metal residues and pathology. Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer. We investigated the association of hypertensive encephalopathy (HE) with subsequent dementia. The promoter and enhancer of the inactive chicken beta-globin gene contains precisely positioned nucleosomes. The principal elements required to make an appropriate surgical decision also are outlined. In the present work, we intend to determine the capacity of human lymphocytes to recognize subfragments of the serine-stretch protein SERP, a blood-stage antigen from Plasmodium falciparum.

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Neurological examination revealed sensory disturbances in various locations, weakness of the right lower extremity, mild swallowing disturbance, and bowel and bladder difficulties. Base of tongue (BOT) is a difficult subsite to examine clinically and radiographically. Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study. This US assessment is currently based on general tendinopathy references and not well-defined US entities. Co-expressed M1- and M23-AQP4 formed aggregates of variable size that segregated due to diffusional sieving of small, mobile M1-AQP4-enriched arrays into lamellipodia and preferential interaction of large, M23-AQP4-enriched arrays with the extracellular matrix. In each case surface immunoglobulins were found with monoclonal expression of light chains. Clinical factors commonly thought to be predictive of abscess formation following perforated appendicitis were not reliable predictors of this outcome. This study was conducted at several centers in the United States.

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The ERG is the expression of the changes of the electrical potential in the retina after a luminous stimulus. Side effects of GnRHas can be ameliorated by the addition of addback therapy. Data were analyzed according to the standards of the Neonatal Cochrane Review Group. New report on the bionomics of Coquillettidia venezuelensis in temporary breeding sites (Diptera: Culicidae). The effect of crate height on the behavior of female turkeys during commercial pre-slaughter transportation. Treatment Effect on Recidivism for Juveniles Who Have Sexually Offended: a Multilevel Meta-Analysis.

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Resistin has been linked to obesity, type 2 diabetes, inflammation and atherosclerosis but the results of animal and human studies have been at variance. Expectation-maximization algorithms for fuzzy assignment of genes to cellular pathways. Propagation of epileptiform activity from neocortex and hippocampus in rabbits and monkeys. Benefits and risks of an intensive very-low-calorie diet program for severe obesity. Our results indicate that prodigiosin could be a good candidate for the treatment of Chagas disease. We ask if FK506 biases STAT activation toward a TH2-type response.

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Premature rupture of fetal membranes at term: sequelae of conservative management. Levels of endothelin and beta-human chorionic gonadotropin and their relationship in patients with pregnancy induced hypertention. Molecular phylogeny of the Blastocladiomycota (Fungi) based on nuclear ribosomal DNA. Fluoroquinolone-resistant acute prostatitis requiring hospitalization after transrectal prostate biopsy: effect of previous fluoroquinolone use as prophylaxis or long-term treatment. Heparan sulphate also had an antiangiogenic effect in the chorioallantoic membrane, while keratan sulphate, dermatan sulphate or chondroitin sulphate had no such effect. Preoperatively, and at 3, 12, and 24 months after surgery, clinical and radiographic examinations were made, and joint-fluid samples were aspirated. We were able to observe the clinical and therapeutic course for about one year and three months. Following this, in December 1997, a controlled release capsule containing monensin was approved for use in dairy cattle as an aid to prevent subclinical ketosis. The isolation of spirochetes from severe ovine foot disease has been reported recently by our research group.

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Safeguarding a confidence has been and continues to be an expected professional behavior. Transfer of patients receiving advanced mechanical circulatory support. Plasmacytoid, T cells (PTC) occurring in cases of chronic non-specific lymphadenitis were investigated using a panel of monoclonal antibodies and cryostat sections. This study showed that hormone treatment has a significant influence, both directly and indirectly, on the bodies of prostate cancer patients. Improved communication and higher clinical quality dominate the future of the medical profession.

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Alleviating the pain of unresectable hepatic tumors by percutaneous cryoablation: Experience in 73 patients. Efficiencies of DNA inactivation and mutation induction by tritiated glycerol in bacterial systems. It is therefore suggested that the mode of action of these compounds interfering with the development of these pathological states share some common trends. Cells resuspended in fibrin formed intracellular vacuoles that coalesced into lumenal structures. Night shift work associated with great physical effort can lead to a significant rise in blood pressure and heart rate, all the more if the subject suffers from hypertension thus predisposing the patients to coronary events. distal splenorenal shunt for the clinical management of esophageal varices in patients with child class A and B liver function: a prospective randomized trial. Relationship of service corporation to the sponsoring constituent society. An urgent coronary angiogram demonstrated an intimal tear with a dissection of the left anterior descending artery.

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Our results suggest that the rat 5q22-23 fragment controls a part of the cell differentiation program including morphology, attachment to extracellular matrix, and synthesis of some matrix proteins, particularly alpha 1 and alpha 2 chains of collagen IV. At the cellular level, these peptides were localized in the cytoplasm and extracellular matrix. Novel mutations in COL4A3, COL4A4, and COL4A5 in Chinese patients with Alport Syndrome. We report efficacy and safety results of vatalanib in advanced gastrointestinal stromal tumour (GIST) resistant to imatinib or both imatinib and sunitinib. With this case report, we highlight one of the unusual presentations of PAN and the favourable response to immunosuppression with pulsed dose steroids. A simple and powerful microfluidic array chip-based electrophoresis system, which is composed of a 3-D microfluidic array chip, a microvacuum pump-based negative pressure sampling device, a high-voltage supply and an LIF detector, was developed. The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain?. These data are in agreement with the model that IL-1 stimulates production of IL-2 from lectin-stimulated lymphocytes. To describe a series of children in whom secondary enuresis occurred after a motor vehicle accident. Cisplatin sensory neuropathy is not equally severe in all patients and may progress even after drug withdrawal.

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Our derived centiles were clearly lower than those from Western studies showing the importance of racial differences between populations. Histogram analysis revealed the responses of maximal potential compactness to stimulation of the RF. Molecular anatomy of the alkaliphilic xylanase from Bacillus halodurans C-125. Isolated DNA dosimeters were also exposed to daily sunlight for comparison purposes. Somatosensory gating is altered and associated with migraine chronification: A magnetoencephalographic study.

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Consistent with this, expression of a sizable proportion of PMA-inducible genes was not significantly affected by H7. Although lacking the components that characterize the acquired immunity systems of vertebrates, invertebrates nevertheless possess effective general innate immune mechanisms which exhibit striking parallels with those of vertebrates. Koilocytosis in oral squamous cell carcinoma: what does it mean?. Effect of disodium cromoglycate (Intal) on the course of endogenous steroid-dependent bronchial asthma. And it is considered to have great significance for promoting the development of the present acupuncture and moxibustion theory since it is effective in both preventing and curing diseases caused by deficient and stagnation conditions such as the wei (flaccidity) syndrome, bi (arthralgia) syndrome, paralysis, dementia, asthma and so on. In this article, we outline procedures for the dissection of intact kidneys and the isolation of the ureteric bud (UB) and the metanephric mesenchyme (MM) from mouse embryos. The combination of FDG-PET/computed tomography and duplex ultrasound is useful to diagnose mycotic aneurysm in the setting of bacterial endocarditis. Advances in the understanding of FM pathophysiology and clinical presentation have improved the recognition and diagnosis of FM in clinical practice. These promising data open the way to new therapeutic approaches in muscle diseases through targeting of the myostatin pathway. Antigenic and genetic stability of bovine immunodeficiency virus during long-term persistence in cattle experimentally infected with the BIV(R29) isolate.

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These new dimers are compared with other models proposed by crystallography or EM and AFM studies. Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation. Continued education of primary care physicians and the general public regarding the definition of SS and the eligibility for GH therapy should be pursued. However, suicide rates are not converging as hypothesized, but are in fact rising in both countries. He underwent long-term care with a respirator after mediastinal drainage operations. Applications of gallium-67 scintigraphy in the management of patients with malignant lymphoma. SEX-SPECIFIC REPRODUCTIVE CONSEQUENCES OF BODY SIZE IN THE SOLITARY ECTOPARASITOID, DIGLYPHUS BEGINI. Living with a person who experiences mental health problems can have an adverse effect on well-being. Recovery was uneventful after the initiation of antimicrobial therapy.

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The structural and morphological differences between nanofibers and microvesicles were investigated directly using several spectroscopy and microscopy techniques. In order to quantify the amount of protein in the small intestinal brush border region at different villus sites, cryostat sections of adult rat jejunum were stained with Naphthol Yellow S, Dinitrofluorobenzene and Coomassie Brilliant Blue and the dye deposits were evaluated cytophotometrically. The induced pluripotent stem cell (iPSC) technology is instrumental in advancing the fields of disease modeling and cell transplantation. We have investigated the mechanism of cyclic nucleotide binding to PKG by determining crystal structures of the amino-terminal cyclic nucleotide-binding domain (CNBD-A) of human PKG I bound to either cGMP or cAMP. Indications for penetrating keratoplasty in a tertiary referral centre in Canada, 1996-2004. Thermal gelation of aqueous hydroxypropylmethylcellulose solutions with can you take valium with cold medicine SDS and hydrophobic drug particles. Therefore, maximal safety and optimal X-ray protection for patients and the members of the team are crucial and should be redefined. Future research should continue to seek empirical support of the core symptoms of ME and CFS to further progress the search for biological markers and treatments.

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Epigenetic regulation of satellite cell activation during muscle regeneration. Given that mammalian telomeric chromatin includes nucleosomes, we investigated the effect of this protein on chromatin structure. These results indicate that the L-arginine-NO-cyclic GMP pathway accounts for most of the inhibitory influence of endothelium on alpha-adrenergic responses in aortic rings. Dietary self-selection can compensate an age-related decrease of rat liver 20 S proteasome activity observed with standard diet. Chlorpyrifos pharmacokinetics and metabolism following intravascular and dietary administration in channel catfish. A comparison between patients with antero-posterior BAV (BAV-AP) or right-left BAV (BAV-RL) was also performed, and the determinants of aortopathy and LV function were investigated.

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Gene structure and chromosomal assignment of mouse GITR, a member of the tumor necrosis factor/nerve growth factor receptor family. These observed changes were primarily in the high alpha band (10-12 Hz) and were larger in electrodes ipsilateral rather than contralateral to the stimulation. Energy expenditure under free-living conditions in normal-weight and overweight women. Physiological concentrations of soluble uric acid are chondroprotective and anti-inflammatory. A concentration gradient was thus obtained using a simple silane-based chemical reaction. Transcription of a Drosophila heat shock gene is heat-induced in Xenopus oocytes.

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