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Calmnir (Clonazepam)
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Calmnir

Calmnir is one of the products that belong to the bensodiazepine group and have a strong sedative effect. It is widely used among people with severe panic attacks and anxiety caused by depression treatment. Thanks to its unique features, Calmnir helps to stop convulsions and epileptic seizures.

Other names for this medication:
Almac, Anxiset, Azpax, Cleps, Cloam, Clonapax, Clonasig, Clonatrac, Clonax, Clonazepam, Cloneepam, Clonotril, Clopam, Closis, Clotweet, Clozorix, Deptune, Dipwell, Easyfeel, Eminaz, Epicloz, Escimax, Escitacalm, Escitrac, Estalonix, Ezinite, Jbcloz, Lonazep, Lonipax, Meloprax, Melzap, Norep, Ozepam, Petril, Prasilex, Prasilife, Repam, Sezolep, Somnolex, Somnotril, Ubitpam, Xenotril, Xitzen, Zeficar, Zepam, Zicam, Zolpidox, Zozep

Similar Products:
Prandin, Medrol, Caverta, Amethopterin, Imovane, Anafranil, Myambutol, Addyi

Also known as: Clonazepam

Description

Calmnir, like other benzodiazepines, while being a first-line treatment for acute seizures, is not suitable for the long-term treatment of seizures due to the development of tolerance to the anticonvulsant effects.

Calmnir has been found effective in treating epilepsy in children, and the inhibition of seizure activity seemed to be achieved at low plasma levels of Calmnir. As a result, Calmnir is sometimes used for certain rare childhood epilepsies; however, it has been found to be ineffective in the control of infantile spasms. Calmnir is mainly prescribed for the acute management of epilepsies. Calmnir has been found to be effective in the acute control of non-convulsive status epilepticus; however, the benefits tended to be transient in many of the people, and the addition of phenytoin for lasting control was required in these patients.

It is also approved for treatment of typical and atypical absences, infantile myoclonic, myoclonic and akinetic seizures. A subgroup of people with treatment resistant epilepsy may benefit from long-term use of Calmnir; the benzodiazepine clorazepate may be an alternative due to its slow onset of tolerance.

Dosage

Calmnir is also used to treat symptoms of akathisia (restlessness and a need for constant movement) that may occur as a side effect of treatment with antipsychotic medications (medications for mental illness) and to treat acute catatonic reactions (state in which a person does not move or speak at all or moves or speaks abnormally). Talk to your doctor about the possible risks of using this medication for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Calmnir.

Do not let anyone else take your medication. Calmnir is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Overdose

Treatment after Overdose. If a person accidentally overdoses on Xanax, Valium, or Calmnir due to interactions with prescription medications, this is unlikely a sign of addiction or abuse. However, if the overdose was the result of benzodiazepine abuse of any kind, help is needed.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Calmnir Wafer dosage information

Side effects

The most common side effects associated with Calmnir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clonazepam in children with seizure disorders. However, safety and efficacy in children with panic disorder have not been established.

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A prediction model for real-time PCR results in blood samples from febrile patients with suspected sepsis. Aim of this study was to determine whether in patients with Anorexia Nervosa (AN) OLA induces weight gain through the modulation of the hunger-satiety regulatory peptides leptin and ghrelin. The sexual dimorphism in 2D:4D was present across ethnic and country groupings, suggesting that it is universal in humans. Inhibition of superoxide dismutase and enhancement of hydroxydopamine autoxidation. A heightened awareness ofthe possibility of this disease can lead to good initial surgical technique and prevention, and to early diagnosis in the eventof stump appendicitis. The objective of our study was to investigate risk factors for AGA severity among a Caucasian population.

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Using an image-processing workstation and special mathematical algorithms, three-dimensional computer animations of fast eardrum motions under static pressure can be generated. After one course of an anthracycline-containing regimen, pathologic cells were identified as CD68 (Kp-1)-positive with myeloid-lineage tumor cells and abnormal karyotypes with 8q21 and 21q22. Cytological studies of palatal mucosa in contact with movable partial dentures. Acetyl disulfide, (CH3COS)2, a major active component in the thiolacetic acid histochemical method for acetylcholinesterase. Acute and long-term effects of vasodilator therapy on resting and exercise hemodynamics and exercise tolerance. Obtained results provide new information on the impact of electric field frequency on OH, which is useful for OH process design. The results of the study confirm the hormone hypothesis of diabetic complications and stress (high adrenaline level) factors of Diabetes Mellitus pathogenesis. It presents in patients who undergo surgery of the prostate early, when their adenoma is generally small and frequently with inflammatory lesions as those of chronic prostatitis.

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Stimulation via a single electrode in the scala tympani or scala vestibuli is characterized by a precipitous input-output function, but current passing from one scala to the other generates a discontinuous function with a shallow slope at low intensities and a steep slope at high intensities. MP may be related with the pathogenesis of HFRS virus and the increase of plasma ET/SP ratio may be an important factor aggravating kidney injury. Thus SIMA was expressed in early fetal stomach, large and small intestines but thereafter only in the normal small intestine. The place of intermittent hemodialysis in the treatment of acute renal failure in the ICU patient. Serum amyloid P component (SAP) is a normal plasma protein, closely related to C-reactive protein, which is deposited together with amyloid fibrils in all forms of amyloidosis. Most of the knowledge on KOPr antagonism is based on drugs with unusual pharmacokinetic and pharmacodynamic properties, complicating interpretation of results. Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure. Impaired clock output by altered connectivity in the circadian network. Some studies show an increased risk of anaphylaxis in patients who are taking ACE inhibitors and beta-blockers, whereas others studies do not show an increased risk.

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Among these isolates, compounds 2 and 4 - 9 exhibited cytotoxicity against cholangiocarcinoma cell line, KKU-100. Diabetic patients received acarbose, 150 mg/day during four weeks and this dose was increased to 300 mg/day during 3 months. Apart from their intense participation in regeneration, these totipotent cells also invariably participate in the formation of new hydra buds. Concomitant diuretic therapy usually elicits a response in patients who fail to respond adequately to monotherapy. Furthermore, we state that, to the best of our knowledge, this is the first documented case of CGD from Libya. High-level expression of human butyrylcholinesterase gene in Bombyx mori and biochemical-pharmacological characteristic study of its product. Influence of mucoid coating on clearance of Pseudomonas aeruginosa from lungs.

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Successful management of vitreous-tube obstruction generally requires manual removal of the condensed vitreous plug with end-grasping forceps. Thus, FISH appears to be useful for the surveillance of patients with HRSBT following BCG therapy. Intensified bioprocess development requires parallelized medium- to high-throughput experimentation with high on- and offline data density across all early scales of the development trajectory from microtiter plate via shake flask to lab-scale reactor. Furthermore, to characterise the duration of pharmacological blockade produced by DHbetaE, the antagonist was examined in the drug discrimination (DD) procedure. We also investigated the protein composition of plastid ribosomes from greening barley leaves and found that it did not change during greening. Study using acs mutants demonstrated that four ACS isoforms, including ACS2, ACS6, ACS7 and ACS8, contribute to ethylene production in response to wounding. Death rates for all age groups have shown steady reductions over the century and are now at or near their lowest points. The PECS is one of the first programs developed in Spanish to train social cognition, and the data obtained support the importance of expand the social cognition programs to non-English language samples.

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To our knowledge, no studies have evaluated associations between livestock production and human infection by other strain types. A total of 1228 women and 1648 men attending the STD clinic at the University Hospital Rotterdam, Netherlands, were examined for HBV infection by determination of hepatitis B surface antigen (HBsAg) and antibodies to hepatitis B core antigen (anti-HBc). DHF also protected the keratinocytes against hydrogen peroxide- and ultraviolet B-induced oxidative damage, while HO-1, ERK and Akt inhibitors markedly suppressed DHF-mediated cytoprotection. These testicular and spermatotoxic changes may be responsible for observed male mediated developmental toxic effects. In this study, we sought to investigate the bactericidal and sterilizing activities of human-like exposures of metformin when given in combination with the first-line regimen against chronic tuberculosis in BALB/c mice. Adolescents with BPD had significantly higher prevalence rates of 22 of the 24 symptoms studied than psychiatrically healthy adolescents. Platelet monoamine oxidase activity was determined in 52 unipolar depressive patients, 26 patients with bipolar affective disorder and 48 controls using phenylethylamine as substrate.

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The objective of this study was to evaluate the effect of a potent P-gp inhibitor, GF120918, on the systemic pharmacokinetics and antinociceptive pharmacodynamics of a single intravenous dose of morphine in rats. Although HLA-DR4 is associated with IDDM in many populations, DR4-positive HLA haplotypes vary greatly (relative risk from greater than 10 to less than 1). Workers in garbage treatment plants were higher exposed to airborne microbial agents. The gain of efficacy of this innovative treatment must be defined. Calcific uremic arteriolopathy (CUA) is a rare but serious life-threatening complication of CRF that manifests as painful nonhealing eschars in association with panniculitis and dermal necrosis. Experimental and theoretical methods were used to investigate the linearity of the stress response of articular cartilage to ramp and sinusoidal tests in confined compression, as well as the role of cartilage-porous platen and lateral confinement boundary conditions in determining material responses. Assistance for an aged patient with chronic neurological disease in an effort to increase the extent of his ADL. Effects of anti-immunoglobulin antibodies on murine B lymphocytes and humoral immune responses. Anchorage-independent growth and the expression of cellular proto-oncogenes in normal human epidermal keratinocytes and in human squamous cell carcinoma cell lines. While the moderate number of studies does not allow for further differentiation between sub-types of music intervention, the sub-group comparisons indicated promising pathways for future systematic reviews.

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Kinetic release of triptolide after injection of renal-targeting 14-succinyl triptolide-lysozyme in a rat kidney study by liquid chromatography/mass spectrometry. This review of the literature will give emphasis on established methods and programs for the prevention and control of the two most common oral diseases, dental caries and periodontal disease. The application of liver transplant techniques and liver mobilization procedures not generally familiar to urological surgeons facilitates wide exposure and proximal control of the IVC for tumors cephalad to the confluence of the hepatic veins. Increase of the circulation halflife ranged from 2- to 150-fold depending on the protein/lipid ratio of the liposomal formulation, liposome size, and the lipid composition of liposomes. remanei, which could thus represent an important competitor for a similar ecological niche. OxLDL and macrophage survival: essential and oxygen-independent involvement of the Hif-pathway. Functional morphology of the gills of the bowfin, Amia calva L., with special reference to their significance during air exposure. Furthermore, downregulation of FOXR2 remarkably reduced the protein expression of Shh, Gli1, and Ptch1 in SW480 cells.

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The prevention and management of HFS and mucositis are important for continued treatment. ICA revealed four task-related components consistent with the previous literature: 1) medial prefrontal cortex (PFC) network, associated with self-referential processes, 2) medial temporal lobe (MTL) network, associated with memory, 3) frontoparietal network, associated with strategic search, and 4) cingulooperculum network, associated with goal maintenance. Some side-effects, usually referred to as hormonal, increased during the levonorgestrel-IUD use, but did not result in higher termination rates than with the Nova-T device. Syntactic comprehension, verbal memory, and calculation abilities in Spanish-English bilinguals. Additionally, we discuss controversies and future directions, such as novel technologies and indications, mechanical ventilation of the native lung during ECLS, and ethics considerations.

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Delayed gastric emptying after pancreaticoduodenectomy: influence of the orthotopic technique of reconstruction and intestinal motilin receptor expression. The frequency of allelism, used in a manner analogous to capture-recapture of animal populations, indicated that the number of genes capable of mutating to lethal had a 95 per cent probability of being in the range 247 to 1140, although excluding possible heterotic and synthetic lethals altered this to 309 to 3568. The National Eye Institute Visual Function Questionnaire (NEI-VFQ) is not sufficient to assess vision-related quality of life in patients with vision impairments caused by neuroophthalmic deficits. In particular, the prominent occipital encephalocele has not been observed before in a terminal 4q deletion. PS-24 induced hypermotility, while TRH induced slight hypomotility. We also show that increasing the level of the beta-oxidation enzyme thiolase results in enlarged peroxisomes. Determination of covalent binding to intact DNA, RNA, and oligonucleotides by intercalating anticancer drugs using high-performance liquid chromatography. The strain distribution pattern of responsiveness shows a combined influence of non-H-2 and H-2 genes. These results correlate temporally with the previously reported Cr(VI)-induced RAD51 cytoplasmic accumulation. Hydrographic measurements were made from transect (spatial survey) or anchor station (temporal survey) deployments over a variety of wind stresses and tidal states during the upwelling seasons of 2006 through 2008.

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The triage efficacy of fine needle aspiration biopsy for follicular variant of papillary thyroid carcinoma using the Bethesda reporting guidelines. Neoplasms included 32 lymphomas, 13 primary bone neoplasms, 5 melanomas, 5 thyroid neoplasms, 9 soft tissue sarcomas, 5 mast cell sarcomas, and 15 carcinomas. Simultaneous labeling of vagal innervation of the gut and afferent projections from the visceral forebrain with dil injected into the dorsal vagal complex in the rat. Angiopathy plays only a minor role, while immunopathy has implications for antibiotic treatment, in that bactericidal agents are needed. The EE cell line could be useful for the study of mechanisms involved in the interaction of EECs with the underlying myocardium and cardiac interstitium and as useful tools in understanding their role in diseased states of heart. Panel -- educational programming for the hearing-impaired: present and future. Using kinetic data it was estimated that the modification of 1 mol arginine per mol enzyme was sufficient for inactivation to occur, whereas amino acid analysis indicated that 4 mol arginine had been modified. It was highly induced by organic hydroperoxides, weakly induced by H2O2, and not induced at all by a superoxide generator. Issues in the dose-response analysis of the Mayak case-control study.

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These transduction mechanisms may provide potential targets for the treatment of CPPD crystal deposition disease. Female gender is associated with sub-optimal haematuria evaluation, while older patients are evaluated more thoroughly. Hence, F3/F11 can either be expressed throughout the cell or be polarized to the axons. The Memorial Symptom Assessment Scale-Short Form (MSAS-SF) is designed to evaluate physical and psychological symptom burden in advanced cancer patients. The higher solid/liquid ratio (w/v) also affected the metal dissolution by arresting the cell growth due to increased metal concentration in the waste sample. Evaluation of a teaching and treatment program in over 4,000 type 2 diabetic patients after introduction of reimbursement policy for physicians. To further promote the use of spironolactone as a first-line systemic treatment for women with acne, there must be more prospective controlled trials.

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In this paper, we use Shannon entropy and relative entropy to measure the diversity and selection pressure flagyl drug category by an antibody in each amino acid site of H3 HA between the 1992-1993 season and the 2009-2010 season. The role of 3-canal biomechanics in angular motion transduction by the human vestibular labyrinth. The classical and the one-and-a-half ventricular options for surgical repair in patients with discordant atrioventricular connections. A molecular approach to myelination using recombinant retroviruses. There was a statistically significant increase in illumination after replacement with new batteries, replacement with a new bulb, replacement with new batteries and a new bulb, or attachment of a disposable blade. In absence of overt cardiovascular disease, patients with low T3 syndrome present an increased concentration of NT-proBNP. The L1Tc non-LTR retrotransposon of Trypanosoma cruzi contains an internal RNA-pol II-dependent promoter that strongly activates gene transcription and generates unspliced transcripts. It is shown that a pair of lateral midbody papillae, the centrids, are prominent sensilla in the adult male and female worm. Of 13 patients with complex partial seizures who experienced stuporous states during treatment with sodium valproate (VPA), 4 received VPA only, 4 VPA and phenobarbital (PB) and 5 VPA, PB, and a third anticonvulsant. Hyperpnea: the common stimulus for bronchospasm in asthma during exercise and voluntary isocapnic hyperpnea.

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The present study was undertaken to assess both the levels of acidic and basic fibroblast growth factors in spinal cord cultures and to determine how they were presented to responsive cells. These recordings may be important for practical purposes, but they still have many limitations concerning the amount of the atrial potentials which can be recorded together with sinoatrial potential. Cyclopentylamine 4 was identified as a potent dual NK1R antagonist-SERT inhibitor. Thalamic glutamate levels as a predictor of cortical response during executive functioning in subjects at high risk for psychosis. GDNF and neurturin signal what the generic form of zantac through a multicomponent receptor complex containing a signaling component (the Ret receptor tyrosine kinase) and either of two glycosyl-phosphatidylinositol-linked binding components (GDNF family receptor alpha components 1 and 2, GFRalpha1 or GFRalpha2), whereas the receptor for persephin is unknown.

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In this single-center retrospective observational study, data were analyzed from 59 women aged 23-42 years with the desire to have children and who underwent LM for symptomatic uterine leiomyoma between January 2001 and December 2006 and subsequently delivered at our hospital. Significant information has accumulated in the past year concerning the mechanism of transposition and the intermediates involved. Demonstration of hepatitis B virus DNA by polymerase chain reaction in the serum and the liver after spontaneous or therapeutically induced HBeAg to anti-HBe or HBsAg to anti-HBs seroconversion in patients with chronic hepatitis B. To evaluate retrospectively the efficacy of administering an atenolol 50 mg price anticonvulsant medication, clonazepam, by dissolving tablets slowly orally before swallowing, for the management of burning mouth syndrome (BMS). This was a large, longitudinal study with an average 3-year follow-up period. The possibility of ARF warrants careful monitoring of urinary output and renal function at the onset of non-steroidal anti-inflammatory therapy in patients with altered or precarious haemodynamics. Also, a switch in gene regulation from up to down regulation, with increasing potency, was seen both in genes involved in metabolic functions and cell cycling. The structural data of the BRS-3 genes derived from this study will permit future investigations of the mechanisms regulating their expression. It is important to report poisonous substances causing vital organ failure to increase awareness among general population as well as health care providers.

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The presence of urea indeed destroys the secondary structure of bound histones, causing changes in the conformation and thermal stabilities of histone-bound base pairs in nucleohistone. USING FREQUENCY DISTRIBUTIONS TO DETECT SELECTION: INVERSION POLYMORPHISMS IN DROSOPHILA PSEUDOOBSCURA. Participants completed the demographic questionnaire, the Center for Epidemiological Studies for the intensity of depression, and the Devaluation-Discrimination Scale to assess stigma. The qualitative and quantitative changes were comparable to those mediated by IL-6 or leukemia inhibitor factor (LIF). Identification of a pH-sensitive non-mitochondrial calcium pool. Extracellular release of antigenic proteins by Helicobacter pylori. CTA can provide important information for the initiation of therapy in patients with acute hemispheric ischemia. These ultram er cost recently recognized forms of cerebral gray and white matter dysmaturation suggest new therapeutic directions centered on reversal of the processes that promote dysmaturation. A model is presented suggesting that chloroplast lamellar membranes have a binary structure, which digitonin splits into two components. This study provides statistical support to the emerging idea of the existence of distinct anthroponotic C.

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The first was a prospective survey of nasopharyngeal (NP) carriage in child care centers. Evaluation of a PCR-immunoassay technique for detection of Neisseria meningitidis in cerebrospinal fluid and peripheral blood. Pediatric acoustic schwannoma showing rapid regrowth with high proliferative activity. The diseases have significant socio-economic impact through gross disfiguration, morbidity and mortality worldwide. Measured average DC offset values from exemplar recorders may not be directly comparable to those of submitted digital audio recordings without exactly duplicating the acoustic environment and microphone/recorder configurations. Our data suggest that this expression system is useful for studying the catalytic mechanism and biological significance of these human peroxidases. Over one-quarter (27.6 percent) of the visits were to general and family physicians.

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Residual and dentigerous cyst related to a supernumerary tooth, involving penetration of the maxillary sinus. coli S phi 874 but was found to be abnormal in its distribution over the surface membrane. Diabetic nephropathy is the leading cause of chronic renal disease and one of the major causes of cardiovascular mortality. To obtain new information, we studied with scanning electron microscopy (SEM) the development of carcinogenic changes in the epidermis of mice induced by DMBA-TPA, DMBA alone, and by the cocarcinogen TPA alone. Calcinosis cutis following the administration of intravenous calcium therapy.

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The US examination involved both the static and dynamic scanning. Published reviews attempt to synthesize results from primary studies validating these scales and based on the findings recommendations may be given, for example which pain scales are the most appropriate for use in different pediatric populations. White cohorts experienced consistent declines in ADL disability calcitriol child dose but Blacks saw little improvement with some evidence for increased disability. Now cardiac CT can demonstrate these anomalies with ease and facilitate appropriate treatment. Genetic libraries of the plastid 16S rRNA gene were constructed on picoeukaryote populations sorted by flow cytometry, using two different primer sets, OXY107F/OXY1313R commonly used to amplify oxygenic organisms, and PLA491F/OXY1313R, biased towards plastids of marine algae.

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Expression and characterization of peripherin/rds-rom-1 complexes and mutants implicated in retinal degenerative diseases. Neurocentral synchondrosis fracture in immature spines associated with pedicle screw type fixation devices. A 30-min light period was provided to short day (6L : 18D) photosensitive turkeys at times when birds were responsive to light (14 h after first light) and at times when birds were unresponsive to light (8 h and 20 h after first light). These inhibitory effects on differentiation were not observed with a carboxyl-terminal truncation mutant or with the unrelated cyclin-dependent kinase inhibitor p16(INK4a), although all these molecules exerted similar inhibition of cell growth. In both cases, IVIg had been administered to facilitate immunosuppressive dose reduction in the context of BK nephropathy. Nine studies involved middle-aged to older male recreational golfers and four studies used younger more skilled golfers. Densitometric and small-angle neutron scattering studies of carbohydrates and carbohydrate-protein macromolecules. Optical beam dynamics in a gas repetitively heated by femtosecond filaments. GENETIC AND ENVIRONMENTAL DETERMINANTS OF FOOD PREFERENCE IN DROSOPHILA TRIPUNCTATA.

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