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Calgel (Calcitriol)
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Calgel

Calgel is the active form of vitamin D, normally made in the kidney. It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes.

Other names for this medication:
Actical, Alfacip, Alfarich, Alphadol, Apcical, Arachitol, Aristrol, Bonestat, Calbec, Calbory, Calcimet, Calcirol, Calcitriol, Caldix, Calgel, Calosto, Calsonic, Calsure, Caltin, Caltive, Calvical, Devita, Duracal, Estovon, Minroset, Netxod, Osteobel, Politrol, Riecal, Sunmic, Tobalt, Zaxial

Similar Products:
Decadron, Lipitor, Zanaflex, Pyridium, Buspar

Also known as: Calcitriol

Description

Generic Calgel is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calgel are intestine and bone. Generic Calgel receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calgel may also act on the kidney and the parathyroid glands. Generic Calgel is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calgel has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calgel, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calgel in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calgel produces other independent beneficial effects. Calgel is also known as Calcitriol. Generic Calgel treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calgel is Calcitriol. Brand name of Generic Calgel is Calgel.

Dosage

Generic Calgel is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Calgel suddenly.

Overdose

If you overdose Generic Calgel and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Calgel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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