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Calcibloc (Nifedipine)

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Calcibloc is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Adalate, Adefin, Afeditab, Anpect, Aprical, Belnif, Bresben, Calcianta, Calcibloc, Carditas, Cardules, Conducil, Corinfar, Depine, Emaberin, Farmalat, Fenamon, Hexadilat, Marivolon, Milfadin, Nifcal, Nifebene, Nifecard, Nifed, Nifedipin, Nifedipino, Nifedipinum, Nifehexal, Nifensar, Nifezzard, Nilol, Nipidin, Nirena, Nycopin, Nyefax, Sepamit, Siopelmin, Vasdalat, Viscard

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Calcibloc PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Calcibloc and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Calcibloc are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Effects of a 3-day fast on regional lipid and glucose metabolism in human skeletal muscle and adipose tissue. This was the first time that screening procedures on a large scale were carried out exclusively with the applanation tonometer. ThnA1, ThnA2, and ThnA3 were essential for tetralin ring-hydroxylating dioxygenase activity. A phase I/II clinical trial of autologous cytokine-induced killer cells as adjuvant immunotherapy for acute and chronic myeloid leukemia in clinical remission. Liver specimens from 19 HCC cases with HCV infection only were detected for HCV antigen (HCAg) and HCV RNA with monoclonal antibody (McAb) against HCV NS3 antigen by means of immuno-histochemistry staining and in situ hybridization using Dig-labeled full-length HCV cDNA Probe. Patients with malignant bone disease are at a continuous risk for SREs, and bisphosphonates reduce the incidence and delay the onset of SREs. Selective phosphodiesterase type-5 inhibitor treatment of serotonergic reuptake inhibitor antidepressant-associated sexual dysfunction: a review of diagnosis, treatment, and relevance. Relatively less investigation has been done yet in attaining high-performance proteomic pattern classification compared with the amount of endeavours in enhancing data reproducibility.

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Nutritional risk factors for tuberculosis among adults in the United States, 1971-1992. The latero-orbital enlargement of the intraorbital and latero-orbital region of the zygomatic bone resulted in displacement of the orbital contents with a motility disorder of the eyes. The prevalence found in our study is high enough so that we recommend the screening of autoantibodies, especially anti-gliadin and anti-transglutaminase antibodies, in this risk-population of celiac disease. After intravenous or intraperitoneal injection into normal mice, high activity was recovered in liver and moderate activity in spleen, lungs and small gut. To obtain insight into the molecular regulation of embryonic eye development in primitive insects, we studied the expression of wg and genes projected to interact with wg in the grasshopper Schistocerca americana. Seasonal differences in airway hyperresponsiveness in asthmatic patients: relationship with allergen exposure and sensitization to house dust mites. Using a competitive drug ELISA ISMM concentrations were detected up to 330 days after the implantation of the SRDs, whereas after i.m. Maternal cardiovascular function in pregnancies complicated by intrauterine growth restriction. The neurite outgrowth from embryonic hippocampal neurons on laminin was not affected by the addition of DSD-1-PG. Engineering of class I lactate-polymerizing polyhydroxyalkanoate synthases from Ralstonia eutropha that synthesize lactate-based polyester with a block nature.

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Cardiovascular, aerobic, and ventilatory responses to a multistage treadmill test of near-maximal exercise were determined in 208 middle-aged Chinese men to provide standards in health, and to identify differences in relation to hypertension, coronary heart disease, chronic pulmonary disease and stroke. Incidence and diversity of potentially highly heat-resistant spores isolated at dairy farms. Little is known about the effects of enriched CO(2) atmospheres, which may exist in the next century, on natural plant-insect herbivore interactions. These formal and informal exchanges of information by blood centers, hospitals, and outpatient facilities continue to improve the quality achieved by those just embarking on out-of-hospital transfusion programs and those already experienced in this approach. Self insurance: treatment for the hospital malpractice coverage crisis.

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Vagotomy selectively decreased KA-evoked Fos in the NTS while sparing that in other brain areas. A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development. We report the cytogenetic findings in a case of mixed germ cell-sex cord-stromal tumor of the ovary in a 5-month-old girl. Using one pass for each size, smooth tamps were advanced incrementally into one femur of each pair and toothed broaches were advanced incrementally into the contralateral femur. The effect of EPA-E in a state of increased pressor responsiveness during pregnancy due to a deficiency of vasodilatory prostaglandins needs to be determined. The results from the present study suggest that the presence of additional medical personnel can distract the focus of a consultation away from the patient, particularly when the additional participants are professionals rather than students. Pdcd2 effects on HSC emergence were cell autonomous and P53-independent, and loss of pdcd2 function was associated with mitotic defects and apoptosis. They are also somewhat irritated by the fact that patients are chiefly interested in having their health checked, rather than in following up by changing their behaviour.

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Case of seminoma with possible spontaneous regression without extragonadal metastatic lesion. Response familiarization and the paired-associate performance of noninstitutionalized retarded and normal children. Organic field-effect transistors have been developed that function as either n-channel or p-channel devices, depending on the gate bias. Further studies may demonstrate a role for the clinical use of nitric oxide in microvascular surgery. No regulatory activity of the RGS domains was detected for Gsalpha.

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Erythoroblastosis fetalis due to blood group A-B-O incompatibility. To investigate the evolution of natural antibodies against carbohydrates following sensitization, we studied natural antibodies specific for Gal alpha 1-3Gal in patients sensitized to that antigen as a result of perfusion of their blood through porcine livers for the treatment of hepatic failure. The tissue myeloperoxidase activity after reperfusion was lower in group 1 than in group 2. The number of apoptotic bodies found in the small intestine of control non-fasted rats was low. Modifications of receptive fields of cells in the visual cortex occurring spontaneously and associated with bodily tilt. Therefore, in neutropenic patients different regimens of antifungal prophylaxis have been performed for more than 20 years, but the effect of antifungal prophylaxis is controversial. DEEP-SDM facilitates content analysis of encounters between women with metastatic breast cancer and their medical norvasc 10 mg price philippines oncologists. Four weeks later, thalamic lesion volumes were assessed stereologically, and PFC GAD(67) mRNA expression was measured using in situ hybridization. The aim of this study was to evaluate microscopically controlled frontal sinus surgery in these difficult cases.

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Most hemodialysis grafts fail due to a venous stenosis (venous neointimal hyperplasia) which then results in thrombosis of the graft. Functional discrimination of gene expression patterns in terms of the gene ontology. Production of amylase in liquid culture by a strain of Aspergillus oryzae. Our Phase II study results demonstrating high efficacy and low toxicity for a weekly schedule of high-dose 5-fluorouracil/folinic acid (HD5-FU/FA) in intensively pretreated metastatic breast cancer prompted addition of paclitaxel to this regimen in a phase I/II study in outpatients. FGFR3 is a receptor tyrosine kinase (RTK) of the FGF receptor family, known to have a negative regulatory effect on long bone growth. Incorporation in vitro where to buy tretinoin cream in the philippines of DL-leucine-1-C14 into proteins of the rat liver, kidney and diaphragm in presence of various concentrations of albumin. A leukocyte-rich preparation from venous blood was made by lysing the red blood cells.

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Ultra-low-cost 3D gaze estimation: an intuitive high information throughput compliment to direct brain-machine interfaces. The present study suggests that RPR-II may cause testicular toxicity in rats affecting the normal functioning of testis and it also gave some new information in withdrawal studies. Gold particles (diameter, 80 nm) functionalized with a secondary antibiotin antibody were then used as the readout. Skin grafts alone induce T-independent xenotolerance but sensitize the T-cell compartment when transplanted concomitantly with thymus grafts. The detection of oncogene HPV may be a sensitive marker for prognosis of primary benign lesions. Organization of planning, building and operation of health care facilities under conditions of limited resources. To examine the perceived need to alter eating habits among nationally-representative samples from each member state of the European Union (EU). Spider monkey TRIM5alpha, which has an expanded B30.2 domain v3 region due to a tandem triplication, potently blocked infection by a range of retroviruses, including SIVmac, SIVagm, HIV-1, and N-MLV. Since un- or misrepaired DSB lead to chromosomal anomalies which may promote the development of breast cancer, we have studied the potential of mammography X-rays for immediate and delayed induction of chromosomal anomalies in human primary fibroblasts from BRCA1 and BRCA2 mutation carriers.

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The increase in trabecular thickening and density was seen to be localised to those regions underlying common sites of cartilage degradation, the interface of the thickened trabeculae with the normal architecture in the third carpal bone was coincident with a common site of clinical fractures. Spontaneous menses followed by an intrauterine pregnancy after 5 months of treatment with troglitazone, an insulin-sensitizing agent, in a woman with severe HAIR-AN syndrome whose hyperandrogenism previously could be normalized only with depot LA plus oral contraceptive therapy and dexamethasone. Marginal, internal, and surrounding features of the tumors were analyzed, and these findings were correlated with histologic findings. Our data demonstrate for the first time that apoptosis following cold storage and rewarming of human renal tubular cells is accompanied by specific mitochondrial events, and that these events and apoptosis can be suppressed by adding antioxidants to the cold storage solution. Reverse transcriptase-polymerase chain reaction showed that alveolar macrophages isolated from patients with interstitial lung disease as well as immortalized lung epithelial cell lines express thrombin-activatable fibrinolysis inhibitor antigen. Twenty-four h urinary vasopressin excretion was measured by bioassay in 15 patients with untreated hypothyroidism and compared with plasma sodium concentration. The highest ethylene production rates during vegetative growth ranged from 1.6 to 2.5 nmol m-2 d-1 during rapid growth of lettuce and wheat stands, or about 0.3 to 0.5 nmol g-1 fresh weight per hour. The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway disease. To enable firm conclusions on the effectiveness of rehabilitation after joint replacement, future studies have to consider methodological issues such as outcomes evaluated and number of patients included to ensure sufficient power. This pattern persists for at least 8 days in continuous dim light.

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