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Calaptin (Verapamil)

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Calaptin is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Calaptin is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.

Other names for this medication:
Calaptin, Covera, Isoptin, Vasopten, Veramil, Verapamil, Verelan, Verpitos, Zolvera

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Also known as: Verapamil


Calaptin is in a group of drugs called calcium channel blockers. Calaptin is used to treat hypertension, angina and certain heart rhythm disorders. It works by relaxing the muscles of your heart and blood vessels. Calaptin is also known as Verapamil, Calaptin, Isoptin, Verelan, Bosoptin, Covera-HS.


Take Calaptin orally. Do not take Calaptin in large amounts. Do not crush, chew, break, or open a controlled-delivery or extended-release tablet or capsule. Swallow the whole pill. It is important to use verapamil regularly to get the most benefit. If you want to achieve most effective results do not stop taking Calaptin suddenly.


If you overdose Calaptin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Calaptin overdosage: slow heartbeat, fainting fit.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Calaptin SR dosage information

Side effects

The most common side effects associated with Calaptin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Calaptin if you are allergic to Calaptin components. Be careful with Calaptin if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Calaptin if you have poor heart condition, low blood pressure, recent heart attack. Be careful with Calaptin if you suffer from kidney, liver disease, congestive heart failure, muscular dystrophy. Be careful with Calaptin if you take medications such as any other blood pressure medications; buspirone (BuSpar); carbamazepine (Carbatrol, Tegretol); cimetidine (Tagamet, Tagamet HB); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (digitalis, Lanoxin, Lanoxicaps); lithium (Eskalith, LithoBid); lovastatin (Mevacor); phenobarbital (Solfoton); rifampin (Rifadin, Rimactane, Rifater); theophylline (Elixophyllin, Theo-24, Uniphyl); a sedative such as midazolam (Versed) or triazolam (Halcion); an antibiotic such as clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), telithromycin (Ketek), or voriconazole (Vfend); a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta, Ziac), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others; a heart rhythm medication such as amiodarone (Cordarone, Pacerone), disopyramide (Norpace), flecainide (Tambocor), or quinidine (Quinaglute, Quinidex, Quin-Release); HIV/AIDS medicine such as amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir, Kaletra). Do not use potassium supplements or salt substitutes. Avoid eating grapefruit or drinking grapefruit juice while taking Calaptin. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Do not stop taking Calaptin suddenly.

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Effects of experimental alterations in phospholipid composition on the size and number of mitochondria in the flight muscles of the housefly, Musca domestica. Progress on diagnosis of and therapy for drug-induced neuromuscular disorders (discussion). Less easily recognized signs include rigidity of the spine, shortened stride, hindlimb lameness, and indicators of poor performance. This finding suggests that the reperfusion injury or a related effect may be responsible for the clinical phenomenon presented in this study. To study the short-term depression at primary afferent synapses between Adelta fibers and substantia gelatinosa (SG) neurons in the spinal cord, transverse spinal cord slices with dorsal root attached were made from young rats. Paroxysmal ventricular tachycardia with subsequent myocardial lesion. To evaluate the Nutrition Screening Initiative (NSI) checklist as a screening and an awareness/educational tool in an elderly population. Based on these findings, a phase I clinical trial has been conducted in patients with metastatic breast cancer to examine the toxicity profile and immunologic impact associated with vaccination with DC/tumor fusions. The prevalence of neuropsychological impairment was calculated vs 75 matched healthy controls. In conclusion, WTD can be used as an accurate and cost-effective sentinel for human LD.

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Possibilities of partial resection in the treatment of laryngeal and hypopharyngeal neoplasms. 13 adult patients with 22 replanted digits (11 males, 2 females) aged 21-58 years (mean 42.2 years) and 12 adults and adolescents (8 males, 4 females) aged 13-45 years, (mean 26.8 years) following 14 microneurovascular great and/or second toe-to-hand transfers were studied. I257E was obtained by site directed mutagenesis of nitrite reductase from Achromobacter cycloclastes. Evaluation of 2-column agglutination versus conventional tube technique for antibody screening. The stability of Cornell Medical Index scores and symptoms in a military population.

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Percutaneous transluminal angioplasty (PTA) and stenting was performed, but the hypertension persisted. Iterative X-ray Cone-Beam Tomography for Metal Artifact Reduction and Local Region Reconstruction. Diversity of atlantic coastal plain mollusks since the pliocene. We discuss the assignment of new S-alleles which should help to avoid further confusion. D-(-)-2-amino-phosphonopentanoic acid effectively delayed the onset and significantly decreased the incidence of seizures elicited by theophylline and also significantly antagonized the potentiating effect of N-methyl-DL-aspartic acid on seizures induced by a low dose of theophylline. We have successfully used this system two times to provide teleconsultation for severe acute respiratory syndrome (SARS) patients in Shanghai Infection Hospital and Xinhua Hospital. Independent incubation of human umbilical vein endothelial cells (HUVEC) with IgG (IgG-APS) from 12 APS patients caused a large and sustained increase in ROS, which was prevented by the antioxidants vitamin C and N-acetyl-L-cysteine. IgG AND IgM production, however, were fairly resistant under the same conditions. Using data from the 6-day drug exposure assay, RFC1 correlated positively with MTX and negatively with TMTX cytotoxicity. The effect of cathepsins from varied sources on proteinpolysaccharide (PP-L) of bovine costal cartilage and on proteoglycan subunit (PGS) of bovine nasal cartilage.

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Less than half of the patients suffered complications, most of them being minor ones. Acceptability and use of insecticide impregnated bednets in northern Ghana. Among the various agents inducing H2O2 generation in dog thyrocytes, carbamylcholine is the only one which activates Rac1, whereas phorbol ester and calcium increase alone have no effect, and cAMP inactivates it. This study provides health decision-makers with a first estimate of costs and the opportunity to achieve the optimal use of available data to estimate the needs of health facilities in Morocco. It was found that at pH of the background electrolyte above 5 the peak of the drug exhibited a tailing, at pH 6 or higher even a disappearance of the peak in the electropherogram was observed. Using antibodies to basal cell markers, we analyzed biopsies with MGH to profile the distribution and evolution of reserve cells and their relationship to these epithelial components. Examination of the CCR of the histidine utilization (hut) enzymes in cells grown in minimal medium showed that neither the ptsH1 nor the crh mutation individually had any affect on hut CCR but that hut CCR was abolished in a ptsH1 crh double mutant. Indeed, the thrombin generation potentials of the different surfaces varied remarkable: while non-coated surface readily produced thrombin, alginic acid- and chondroitin sulphate-coated surfaces showed a marked reduction and virtually no thrombin was generated in flowing whole blood passing by heparinized surfaces.

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Cat-HEC/dsDNA/H(2)O and cat-HEC/ssDNA/H(2)O systems presented a considerable difference in the extension of the phase separation region. Contractile performance, action potential parameters, and indicators of arrhythmic activity were measured in 10 preconditioned and 10 non-preconditioned muscles. A method for linking discrete surgical and perfusion-related processes of care with cerebral emboli, cerebral oxyhemoglobin desaturation, and hemodynamic changes may offer opportunities for reducing overall neurologic injury for patients undergoing cardiac surgery. Multiple interventions are recommended by evidence-based practice guidelines to prevent VAP, but there is a growing interest in those related to the endotracheal tube (ETT) as the main target linked to VAP. Fibrillin-1 mutations result in the pleiotropic manifestations of Marfan syndrome, and fibrillin-2 alterations cause the overlapping phenotype of congenital contractural arachnodactyly. Understanding the complex pathophysiology of subglottic stenosis along with the wide variety of available surgical options will aid the surgeon in achieving a successful outcome. No other main effects were observed, but there were interactions with proband diagnosis: a syndrome characterised by bizarre behaviour, inappropriate affect, catatonia and poor rapport predicted psychosis in relatives of schizophrenic probands, and a syndrome of depressive: symptoms predicted psychosis in relatives of schizoaffective probands. Additional artifact management is required to improve soft-tissue visualization. Case of the month: a 10-year-old boy with Down syndrome and ichthyosiform changes.


aeruginosa 8830 the genes encoding polyphosphate kinase (PPK) and exopolyphosphatase (PPX), which are involved in polyphosphate synthesis and degradation, respectively. Our experience with early detection and useful diagnosis of pulmonary neoplasms. Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. For a variety of reasons to be discussed in this paper, those most in need of help are least likely to obtain it. Animals improved only slightly from the effects of treatment following a 4-wk recovery period. Values for triacylglycerols, cholesterol, fasting glucose, 2-h glucose, and the sum of glucose values during an oral-glucose-tolerance test were significantly higher in older subjects. The most abundant metabolite visible by proton magnetic resonance spectroscopy (MRS) in human brain is N-acetylaspartate (NAA), which is often used as a marker of viable neurons. This equation can be transformed into an explicit form to find the constitutive equations of the blood provided the detailed motion of the plasma in some neighborhood of a suspended particle is known. To extract this feature, Emotional Prosody Measurement (EPM) was developed, which consists of 1) speech recording, 2) removal of speckle noise, 3) a Fourier Transform to extract the F0-signal, and 4) the determination of SD F0. A reliable application protocol is therefore proposed using a hybrid solution in which either retransmission or retransmission combined with forward error correction (FEC) techniques are used, depending on the channel conditions.

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This region is highly conserved among plant nsLTPs, implicating that nsLTPs are a new family of CaM-binding proteins whose functions may be mediated by CaM signaling. After 72 hours of n-3 fatty acids intake there are changes on membrane composition and decrease of synthesis of prostaglandin (PG), leucotriens (LT) and thromboxanes (TX) of the 2 and 4 series production and substitution for prostaglandin, thromboxanes and leucotriens of 3 and 5 series respectively. Therefore, clinical application of metabolic bone markers for fracture might be useful in the remodeling stage after fracture. The practical aspects of conduct of routine studies, their potentialities and shortcomings are outlined. Methods and strategies to recruit African Americans into cancer prevention surveillance studies. This retrospective study was carried out on 512 women (age range: 38-80 years, mean age: 63) with AUB who attended our hysteroscopy outpatient service from January 1996 to December 2001. Artificial insemination with motile spermatozoa prepared from HIV-infected men using standard procedures has been employed with many HIV-discordant couples. The methods of functional diagnosis, which is also a necessary precondition for the physical rehabilitation of the patients are bicycle ergometry, auxiliary tests for the gaseous composition of blood and exhaled air, determination of the heart volume by means of X-ray, catheterization of the pulmonary artery with a floating catheter, ventriculography, and coronarography. An integrin from shrimp Litopenaeus vannamei mediated microbial agglutination and cell proliferation.

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Among the factors that predispose this kind of accident in various countries, the inadequate practice of recapping needles and inadequate material disposal can be distinguished. The paper is concerned with the results of a new method of investigation--ultrasound fluometry, based on the Doppler effect. A number of possible critiques of this method are entertained in this article. This approach to the external carotid artery is especially useful when structural alterations of the anterolateral neck are present. A thorough clinical and economic evaluation of our actions, methods and preparations for treatment will make it possible to enhance the efficiency and quality of treatment, to avoid not only considerable undesirable drug reactions but also unjustified social costs in the way it is done in many countries. Methods for assessment of tinnitus-specific disability and presentation of the Tinnitus Disability Questionnaire. Several mutations have been identified in different regions of hTR in patients affected by autosomal dominant DC. The 1450 cm(-)(1) band can be assigned to a ring stretch that is unique to the imidazolate form of histidine. To determine the impact of echocardiography on the use of antibiotic prophylaxis in patients with suspected mitral valve prolapse (MVP).

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Mobile thrombi of the right heart in pulmonary embolism: delayed disappearance after thrombolytic treatment. AFLP was used to analyze the genetic diversity among Ochrobactrum strains. Olfactory ensheathing cells: historical perspective and therapeutic potential. adalat 5 mg kapseln These two drugs are significant advances and are likely to have an increasingly important role in clinical anaesthesia in the future. Subcutaneous inflammatory nodule caused by spicules of Hylesia fulviventris (Lepidoptera).

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In the present study an attempt was made to quantify and characterise the changes in the intracranial pressure (ICP) waveform over the wide pressure range covered during infusion studies by means of the central tendency measure (CTM). Attentiveness and visual reaction times were measured repeatedly as were diastolic and systolic blood pressure. Enterococcus faecalis and Streptococcus prochlorperazine maleate 3 mg side effects viridans were found in the culture of middle ear and mastoid effusion. Vitamin D binding globulin in the rat: specificity for the vitamins D. The material was tested with human and monkey plasma and serum and rat serum, and has been used to deplete litre volumes of human plasma.

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The effects of midazolam (0.1-10 mg/kg subcutaneously, 0.1 mg/kg intrathecally) or saline treatment were compared in rats aged 3, 10, 21, and 40 days (adult). Delayed hyphema and intravitreal blood following intrableb autologous blood injection after trabeculectomy. One hour after administration of 100 mg of EACA/kg, mean alpha2-antiplasmin activity was significantly higher than baseline activity. The differences in sorption-desorption behavior of atrazine in the two soils appear to be related to variations in the type and location of organic matter in the two soils. Alteration in the amino acid content of yeast during growth under various nutritional conditions. These include all the transporters previously annotated as such, as well as a similar number of candidate transport proteins that had escaped detection. The fetal acoustic stimulation test evokes significantly more palpated or visualized fetal movement than in controls. Many streptomycetes produce antibiotics thought to protect vegetative mycelia from competing organisms. 15 with two centromeres and two satellite regions is described and its origin postulated. Effect of Triton WR 1339 on cancer dissemination and metastases.

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The choosing method to assess PTA in practice with reliability is the counting of pills combined with a compliance survey. Antegrade femoral nailing through a piriformis fossa starting point in patients who are obese has been demonstrated to be problematic. The resulting PMSE2b mRNA encodes a protein which is indistinguishable from that encoded by the IFNgamma-inducible PMSE2 gene. This article discusses the evaluation of lymphadenopathy, infectious causes of generalized lymphadenopathy, as well as those infections that cause regional lymphadenopathy. The specimens taken from patients treated in surgical wards showed the presence of a mixed microflora, which included aerobic and anaerobic bacteria, primarily Gram-negative rods. In recent studies, we have described persistently reduced CSF OT levels in male rhesus monkeys with significant social deficits.

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These findings will help shape understanding of UTI treatment in relation to other urological disorders in women. We will discuss the etiopathogenic, anatopathological and therapeutical aspects of this lesion for which the diagnosis is histological and the treatment remains conservative with a good prognosis. A computerized device (MST-CARAT), was used validated by comparing the temovate ointment generic test performance measures with the results of the practical driving tests. A common experimental model is necessary to assess therapeutic intervention in lung preservation. Inclusion bodies of type II alveolar cells: species differences and morphogenesis. To ensure that the results of experiment 1 were not influenced by off-frequency listening, the second experiment employed a broadband noise masker. In aged monkey brains, we found that LGI3 accumulated on or near the plasma membranes of neurons, and colocalized with endocytosis-associated proteins and lipid raft markers. Further studies are needed to evaluate the outcome of SILS compared to that of conventional laparoscopic surgery. The goal of our investigation was to determine if the serum bone ALP (BALP) data obtained from the semiautomated ALP isoenzyme assay had a similar pattern of response when compared with the periosteal ALP (PALP) assay for use in pharmacologic screening in rats.

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In the population-based sample, MCSA subjects were older, had less education, performed worse on the Mini-Mental State Examination, and had a family history of Alzheimer disease less often than did ADNI subjects. Primary aortoenteric fistula is extremely rare and difficult to diagnose, and may cause fatal bleeding. To know the most important clinical features of Burning Mouth Syndrome (BMS) in our environment. Case study of a fifteen-month old child with patent ductus arteriosus. This abnormality of EGFR gene expression is closely related to the malignancy of glioma. Effect of Metopirone on the rate of cortisol disappearance from plasma. can you consume alcohol while taking tramadol Finally, in contrast to CREB, phosphorylation of Src and extracellular signal-regulated kinase was enhanced by fenoterol upon TARC pretreatment.

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Significance of neurotropic component in therapeutic effect of the anti-arrhythmia agents. S-acetyl MAG3 was conjugated to biocytin and to the amine-derivitized oligomers DNA and PNA. It suggests that targeted treatment of children with skin sores and household contacts of cases, rather than attempted treatment of all children in the community, could be an effective method of intervention. Acute insulin response (AIR) tests are useful in phenotypic characterization. Repression of Mfn2 caused morphological and functional fragmentation of the mitochondrial network into independent clusters. More than 70 telesurgical staff meetings allowed us to get an overview of this technology, in order to benefit of telemedicine applications for teaching and clinical use. Logistic regression models for predicting use and non-use, and for predicting private versus public sector use, were constructed using the Andersen Behavioural Model as the conceptual framework. Yet tenormin tab 25mg the proposed criteria would apparently allow diagnosis (and therefore treatment) of only severe desire dysfunction. The tomPRO1 locus may be the first example of a nuclear genetic element in plants that encodes two functional enzymes in two distinct open reading frames.

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Relation of early socialization experiences to self-concepts and gender role in middle childhood. The temperature dependence of the thickness and the refractive indices (ordinary and extraordinary) for the lipid bilayer around the phase transition is presented. Given the ubiquity, complexity and diversity of the P2 network, it is not surprising that P2 signaling also contributes to mechanisms of renal disease. Cerebrospinal and testicular irradiation are reserved for relapsing disease. Rats with fatty liver seldom had liver metastases compared to normal rats.

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