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Caditrex (Methotrexate)

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Caditrex is approved to be used alone or with other drugs to treat: Acute lymphoblastic leukemia (ALL), including ALL that has spread to the central nervous system, or to prevent it from spreading there. It is used in adults and children. Breast cancer.

Other names for this medication:
Alltrex, Beltrax, Biotrexate, Caditrex, Carditrex, Cytotrex, Dermotrex, Folitrax, Imutrex, Merex, Methocip, Methorex, Methotrexate, Metorex, Metrex, Mexate, Neotrexate, Nidtrex, Oncotrex, Onotrex, Plastomet, Remtrex, Rextop, Roxate, Tevatrex, Throtex, Trixilem, Vibzi, Zexate

Similar Products:
Clarinex, Periactin, Myambutol, Albenza, Trandate, Xeloda, Depakote

Also known as: Methotrexate


Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis and rheumatoid arthritis), including inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Caditrex dosage information


If you overdose Generic Caditrex and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Caditrex overdosage: nausea, vomiting, stomach pain, diarrhea, blood in urine.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Valproic acid dosage information

Side effects

The most common side effects associated with Caditrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Caditrex can interact with several other medications. It’s not known to interact with supplements or foods.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase the number of side effects or make them more severe.

Caditrex and other medications

Below is a list of medications that can interact with Caditrex. This list doesn’t contain all drugs that may interact with Caditrex.

Before taking Caditrex, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

Caditrex and other diabetes medications

Sometimes your doctor may prescribe Caditrex along with other medications for your type 2 diabetes, such as glyburide (DiaBeta) or insulin. However, this may put you at risk for developing hypoglycemia (low blood sugar).

Hypoglycemia can cause symptoms such as dizziness, sweating, and headache. In severe cases, you may have serious complications such as a seizure or passing out.

Before starting Caditrex treatment, it’s important to tell your doctor what other medications you’re taking.

You should also talk with your doctor about what to do if you develop symptoms of hypoglycemia, especially if you’re taking multiple diabetes medications.

Caditrex and gemfibrozil

Gemfibrozil (Lopid) may interact with Caditrex. If you’re taking gemfibrozil, the level of Caditrex in your body will rise. Gemfibrozil can also increase the amount of time that Caditrex stays in your body.

If there’s too much Caditrex in your body and you’re also taking other diabetes medications such as insulin, your blood sugar can get too low. This can cause symptoms such as dizziness or sweating.

Before you start taking Caditrex, have your doctor review your all medications. They can adjust your treatment as needed.

Caditrex and rifampin

Taking rifampin (Rimactane) along with Caditrex may decrease the level of Caditrex in your body. This means that you may not get enough Caditrex, and it may not work to treat your type 2 diabetes.

If you start or stop taking rifampin while using Caditrex, your doctor may need to change your dose of Caditrex.

Caditrex and topiramate

If you take Caditrex along with topiramate (Topamax, Trokendi XR, Qudexy XR), the level of Caditrex in your body may decrease. This means that the Caditrex may not work well to treat your type 2 diabetes.

If you’re taking topiramate and Caditrex, talk with your doctor. They may recommend changing your dose of Caditrex or monitoring your blood glucose more often to be sure that Caditrex is working for you.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Caditrex and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Caditrex. However, you should still check with your doctor or pharmacist before using any of these products while taking Caditrex.

Caditrex and foods

There aren’t any foods that have been specifically reported to interact with Caditrex. If you have any questions about eating certain foods with Caditrex, talk with your doctor.

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Mental illness and health care use: a study among new neurological patients. This provides a potential mechanism for defect closure in patients with PMVSD. Patterns of medication use in the RRI-CKD study: focus on medications with cardiovascular effects. Repeated skin biopsies of the necrotizing lesions were consistent with pyoderma gangrenosum. The results suggest that neuronal gap junctions play a critical role in the CCI-induced secondary neuronal death. Attention is focused on problems resulting from synthetic, gaseous, and liquid fuel production. It was found that atherosclerosis progresses how long does dryness last with differin gel at a much slower rate in persons over 70 than in those of younger age groups.

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The suggests that impairment of the electrical activity of cardiac muscle may be one of the reasons why victims of cobra bite die. Also, as many female GPs abstain from practicing after having finished a vocational GP training program it will be essential to create work facilities to keep them available for the GP labour market. Joint collagenous tissues obtained from rabbits with antigen-induced arthritis generated mediators of acute inflammation when incubated with fresh normal rabbit serum as a source of complement. Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant neoplasm. Therefore cryofiltration apheresis is safe and effective in treating cryoprotein induced diseases. Angiogenesis and expression of platelet-derived endothelial cell growth factor in oral squamous cell carcinoma. Maturation induced activation of the vacuolar proton pump that enhanced lysosomal acidification and antigen proteolysis, facilitating efficient formation of peptide-MHC class II complexes. The aeropylar area of the eggs is also described for the first time for neotropical sandflies. Carboxylesterases play an important role in the hydrolytic biotransformation of a number of structurally diverse endogenous compounds and medications. Radioimmunologic determination of human growth hormones (STH) in the serum of 62 patients with acromegaly.

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