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Bruffen (Ibuprofen)

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Over-the-counter Bruffen is used to treat fevers and help with mild aches and pain, including headaches, arthritis, menstrual cramps, toothaches, and backaches. The prescription strength of this medication is used to treat moderate muscle pain, menstrual cramps, osteoarthritis, and rheumatoid arthritis.

Other names for this medication:
Artigesic, Avibru, Brufen, Brutex, Bruzen, Cipgesic, Cypaflam, Diclospas, Dolomed, Gesic, Ibrumac, Ibubid, Ibugard, Ibulite, Iburin, Ibusynth, Lumbril, Myofen, Nildol, Orthodex, Profon, Pyrofen, Samson, Spinach, Tabalon, Ultraprin, Xtragesic

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Also known as: Ibuprofen


Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will help you only as long as you continue to take it .

In addition, ibuprofen can be used to treat fever, menstrual cramps, and other conditions as determined by your doctor .

This medicine is available both over-the-counter (OTC) and with your doctor's prescription .


This section provides information on the proper use of a number of products that contain ibuprofen. It may not be specific to Children's Bruffen Grape Flavor. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine .

To lessen stomach upset, you may take this medicine with food or milk .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets and suspension): For fever: Children over 2 years of age—Use and dose must be determined by your doctor. Children 6 months of age up to 2 years—Dose is based on body weight and body temperature, and must be determined by your doctor. For fever lower than 102.5 °F (39.2 °C), the dose usually is 5 milligrams (mg) per kilogram (kg) (about 2.2 mg per pound) of body weight. For higher fever, the dose usually is 10 mg per kg (about 4.5 mg per pound) of body weight. The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor . For mild to moderate pain: Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For osteoarthritis and rheumatoid arthritis: Adults and teenagers—1200 milligrams (mg) up to 3200 mg per day divided into three or four equal doses. Children—Dose is based on body weight and must be determined by your doctor. The dose usually is 30 milligrams (mg) to 40 mg per kilogram (kg) of body weight per day, divided into three or four doses. Infants younger than 6 months of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Bruffen Childrens dosage information

Side effects

The most common side effects associated with Bruffen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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A total of 224 eighteen-week-old hens of the Hyline Brown 98 strain were assigned to 7 groups with 4 replicates of 8 hens each after 10 days of adaptation, and they were fed commercial diets supplemented with 0, 5, 10, 50, 100, 200 or 400 mg/kg (diet) B (H3BO3) for 8 weeks. The cellular mating activity of Ste2p was subsequently probed in vivo. To develop a consensus ultrasound (US) report that could summarize the relevant anatomical characteristics and staging of patients considering the experience of radiologists and dermatologists working on imaging of HS. The origin of the idea, the characters and their development, and the themes and approaches as well as initial responses to the music and the show are described, and the various educational usages are explored. A self-adjuvanting multiepitope immunogen that induces a broadly cross-reactive antibody to hepatitis C virus. The results suggest that SGFO and SLVO affect the autonomic neurotransmission and lipolysis. Soluble purified CD44 protein in liposomes partially suppressed T cell activation in vitro. Facilitation on an intertidal mudflat: the effect of siphon nipping by flatfish on burying depth of the bivalve Macoma balthica. Each protomer has a well-packed dinucleotide-binding fold in which CoA binds.

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Liver transplantation: filling the gap between supply and demand. Parasympathetic vasodilatation is mediated via nitric oxide (EDRF) and is activated during carotid baroreceptor and chemoreceptor reflexes. Persistent hypoxemia occurring as a complication of tricuspid valve endocarditis. Young patients with a history of migraine with aura admitted with symptoms of acute ischemic stroke are at risk of insufficient treatment. For every target region, the distance maps were very similar across the four classes of sampling strategies, with the grand mean correlation coefficient reaching 0.95. Great economies could be made in the National Health Service by reducing medical outpatient follow-ups. TP can be caused by insufficient production or impaired platelet renewal. Education about these issues via parents, schools and health care providers could promote the health status of adolescents. Together with previous studies, these findings also raise the possibility that immune stimulation activates a functionally and anatomically distinct subset of serotonergic neurons, different from the subset of serotonergic neurons activated by anxiogenic stimuli or uncontrollable stressors. However, there are a few notable exceptions where residues thought to be involved in double-stranded regions in all 18S rRNAs are strongly modified in soybean leaf samples.

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Time-dependent reduction in load to failure of wedge-type polyglyconate suture anchors. The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors. We performed TUR in two patients, antibiotic therapy was administered in one patient and 4 patients were managed conservatively. These data show for the first time that EVE not only activates hypothalamic CRF neurons but also increases CRF mRNA expression in the PVN. MB modulated SERT function and suggested that SERT may be an additional target upon which MB acts to produce 5-HT toxicity. Growers can implement weed resistance BMP systems with the confidence that their net returns will be equivalent in the short run, and, in the long term, resistance BMP systems will prevent or delay the evolution of GR weeds in their fields, resulting in substantial savings. The release of an opportunistic pathogen from sterilizer purge exhausts emphasises the importance of proper sterilizer location, ventilation, containment of heavily contaminated loads, and adequate sterilizer maintenance. A cascade bioassay system has been used to quantify the basal and receptor-mediated endothelium-derived relaxing factor (EDRF) activity of pig coronary artery and pig renal artery. The ability to image Argonaute family proteins in live Drosophila cells, (both cultured and within developing embryos) allows for accurate genetic dissection of the pathways involved in the assembly, mobility, disassembly, and other dynamic processes of Argonaute-containing bodies. A case of total thoracic ectopia cordis with double-outlet right ventricle and ventricular septal defect is presented.

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A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. Her conscious level continued to deteriorate and she died, post mortem examination showing small adrenal glands and cerebral oedema. Side effects and toxicity in the combined regimen of thiacetazone and isoniazid in Morocco. Bovine herpesvirus-1 (infectious bovine rhinotracheitis virus)-based viral vector which expresses foot-and-mouth disease epitopes. Temperament, activity, and expectations for later personality development. Proponents of therapeutic ultrasound suggest it can decrease pain by resolution of inflammation processes and reducing the pressure on pain sensitive structures by haematoma and oedema.

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The understanding of the molecular mechanisms of these non-circadian activities of the circadian proteins will ultimately lead to the improvement in prevention and treatment of age-related pathologies. About one third of the lamina I neurons labeled after injections of a retrograde tracer into the region surrounding the brachium conjunctivum received contacts from immunoreactive varicosities. Birds discriminate innately between conspecific and alien songs, but vocal perception is subsequently enriched by experience. Of 5,000 screened colonies of the contralateral library, 30 colonies contained sequences that were repressed in the distal segment after nerve crush. The current study outlines an investigation of individual differences in brain function associated with ADCYAP1R1 genotype. Other indicators such as haemoglobin, bicarbonate, total cholesterol and HDL cholesterol levels were studied. Simulations and experiments are presented to verify the effectiveness of the proposed algorithm. Potential adverse effects identified through preclinical safety tests with rh-HGF include a decrease in blood pressure (BP) and an increase in urinary excretion of albumin. Mist-CVD ZTO films are mostly polycrystalline, while those synthesized by spin-coating are amorphous. However, the physiological functions of Ppp5 have not been reported.

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We find that love triangles are a more important motive when females commit homicide than when males commit homicide. The Established Acute Surgical Unit: A reduction in nighttime appendicectomy without increased morbidity. Since it has been reported that SRIF concentrations are significantly reduced in the frontal cortex and hippocampus of demented parkinsonians and patients with senile dementia of the Alzheimer type and that levodopa treatment induced various psychiatric side effects, the results of the present study suggest some relationship among levodopa treatment, SRIF depletion and the demented state. The serodiagnosis of tuberculosis in children: an evaluation of an ELISA test using IgG antibodies to M. All tumor cells tested expressed mRNAs for alpha 5, alpha IIb, beta 1 and beta 3. Term healthy newborn control infants from the prospective Development after Infant Surgery (DAISy) study were included. Our findings demonstrate that this methodology is effective for sample collection, mailing, and diagnosis of this pathogen. The precise differentiation of different phenotypes of SDBs has improved substantially in recent years. VARIATION IN GENETIC ARCHITECTURE OF CALLING SONG AMONG POPULATIONS OF ALLONEMOBIUS SOCIUS, A. The effect of pH on the kinetics of intra- and extracellular uptake of Al in Fontinalis antipyretica: changes in the cellular contents of K, Mg, and Ca.

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They can be caused by mechanical factors as bone fragments or muscle imprisonment. Urinary tract infection in stone patients and in patients with indwelling urethral catheters. Amongst patients with a very small or a unconfirmed AMI, factors reflecting their clinical history, including age, a history of AMI and current smoking, as well as factors reflecting their metabolic status, including S-gamma GT and S-glucose, were important predictors for the long-term outcome. Subthreshold stimulation of Ia fibers of the median nerve seemed to have a smaller facilitatory effect. The determination is based on a theory for the dispersion, at low electric field strengths, of analytes that are solubilized by only the micellar phase. Results for all parameters were identical in first-time VA shunt operations and revisions. Students from six allied health degree programs undertaking placements in Tamworth and Taree were invited to participate. We combined data from Medicare, the National Mortality Followback Survey, and the National Medical Expenditure Survey to estimate total national expenditures for health care according to the age at death. This oil presents useful source of polyunsaturated fatty acids and essential PL for diets aimed at prevention of heart disease.

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Biochemical, histological and crystallographic studies were carried out on the pure exocrine pancreatic juice of calcium treated dogs and of normal dogs. Triptolide reduces prostate size and androgen level on testosterone-induced benign prostatic hyperplasia in Sprague Dawley rats. Triplet-sensitized photorearrangements of six-membered-ring 2-phenylallyl phosphites. CT is useful in evaluating subtle bony erosion and intra- and extraosseous pseudotumors. The absence of anesthesia-related cardiac arrests in such patient population has demonstrated that adopting quality improvement measures, teamwork approach and applying strict, but updated and evidence-based, guidelines are essential in the prevention of such catastrophes. A careful examination of the statistical results shows some functional relationships between the factors, which should be considered in designing more detailed factorial experiments to enable the establishment of equation models for predicting the release profile of theophylline from our CPP matrices under any given dissolution condition. Experiences with nitrous oxide-fluothane-epontol mixture anesthesia in ambulatory interventions. Group 2 consisted of 42 hips that were treated in 2000 using a three-point fixation device for the pelvis.

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Mutation of the Ets site blocks ERM-mediated promoter activation in E10 cells. Cloning of prokaryotic genomes in yeast artificial chromosomes: application to the population genetics of Pseudomonas aeruginosa. For each type of parameter, patients have been allocated to one of three levels, each level being established to evaluate whether dialytic treatment should be undertaken as hospital centre dialysis (HDC) or in a facility off the hospital. This finding raises the possibility that a hormonal ligand affects the expression of a homeobox segmentation gene early in embryonic development. No detectable clogging or interference was observed tenormin 25 mg uses in urdu using venous blood samples. A very compact and innovative pulse shaper is proposed and demonstrated. Distribution of P2X receptor subtypes in rat bladder and ureter has been investigated using specific polyclonal antibodies to P2X1 through to P2X7 receptor subtypes with immunohistochemical methods.

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The role of second-look surgery in the management of advanced germ cell malignancies. However, it is also necessary to note that the results obtained through such biochemical analyzes are greatly affected by the quality sildigra super active 100 reviews and properties of the antibodies used, as well as by the immunoprecipitation conditions employed, including buffer contents and/or salt concentration. Digital holography makes it possible to acquire quickly the interference patterns of objects spread in a volume. Measurement of arterial stiffness is an accurate method of assessment of endothelial dysfunction, together with other noninvasive methods, in the diagnosis of atherosclerotic burden in patients with MetS. IPLA could be considered a viable option for early postoperative analgesia in certain laparoscopic operations. Aldrin and lindane impact on acid and alkaline phosphatase activities of prawn, Metapenaeus monoceros: in vitro study.

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Moreover, autophagy-deficient cells exhibit reduced levels of matrix metalloproteinase 2 and WNT5A. In homing performance, pups from MA- and saline-exposed dams learned slower to return to the home box than pups from control dams. It was previously found that NO-deficient hypertension is accompanied by structural remodeling of the cardiac muscle and large coronary arteries. Finally, PVF monitoring has the potential to an increasing role in AF ablation procedures. Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: evidence for the involvement of multiple receptors.

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Behavioural studies indicate that the motor command for reaching towards a target with the forelimb is to a large extent mediated in the C3-C4 propriospinal system, whereas the command for taking of the object seems to be organised in the interneuronal systems of the forelimb segments, not depending on an integration in the C3-C4 propriospinal relay. By RNA blot analysis, this gene is expressed in cultured cell lines derived from a number of different tissues. However, more recent data from two studies, one using confocal microscope analysis of migrating retinal arbors in vivo and the other investigating the requirement for protein kinase activity in map formation, point to a possible divergence in the cellular events underlying synapse stabilization in the developing visual system of the frog and LTP in the mammalian hippocampus. The method can be used without limitations for any field profile and emulates the underlying physical and biological effects significantly better than all other presently known methods. Structures of the catalytic domain of pyrrolysyl-tRNA synthetase (archaeal PylS or bacterial PylSc) revealed binding sites for tRNAPyl and pyrrolysine. Effects of selected pharmaceutically active compounds on treatment performance in sequencing batch reactors mimicking wastewater treatment plants operations. The thoracic squamous cell tumors are adequately treated by an abdominothoracic resection with abdominal and mediastinal lymph node dissection. Clusterin (CLU) is a multifunctional glycoprotein that is overexpressed in prostate and breast cancers.

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graminearum with both a reporter gene containing a homologous trichothecene pathway gene promoter (TRI5) and a gene encoding a heterologous trichothecene pathway transcription factor (TRI6). The current number of surgical deaths was obtained from the 1995 MEDPAR file of the Medicare claims database. The results suggest the possibility that intravenous administration of ethane-1-hydroxy-1-diphosphonate and oral steroids may be helpful for the treatment of fibrodysplasia ossificans progressiva, but more control data on the spontaneous resolution of early flareups are needed. The kinetics and magnitude of the in vivo inflammatory responses examined were indistinguishable in the two populations across the broad range of biomarkers examined, despite the fact that obese women had higher baseline inflammatory status. Non-contact mapping was used to examine the effects of SVE from 25 sites on 10 infarct-related VT circuits. Reduced interleukin-1 responsiveness in immune system and central nervous system of inbred polydipsic (STR/N) mice.

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Mutations at the steel (sl) and dominant white spotting (W) loci in the mouse affect primordial germ cells (PGC), melanoblasts and haemopoietic stem cells. Simultaneous enzyme immunoassay for the screening of aflatoxin B1 and ochratoxin A in chili samples. Epiretinal membrane or previous PSTA result in less resolution of CST, but do not significantly affect visual improvement. In paralyzed rats, 5-HT levels were unchanged, but the 5-HIAA/5-HT ratio was elevated, especially in the compressed segments. Dental treatment requirements of active duty Navy and Marine Corps personnel. To increase knowledge of the diversity and specificity of sustained attention deficits in children with attention-deficit hyperactivity disorder (ADHD), with special reference to the issue of distinguishing between children with ADHD and children with other psychiatric diagnoses.

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A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye. Types of cancer-related zocor generic substitute pain (i.e., somatic visceral, or neuropathic), pain intensity, pain duration, quality of pain, QOL, and mood states. U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. The analysis cutting off the extreme combines the method of components with the least square method, as applied to the peaks of the Gaussian shape. However, because calcium levels change along the length of lesions, it is important to assess the length of calcium using serial cross-sectional images. Studies were included if they were peer-reviewed, written in English, and included a population meeting standardized ultra-high risk criteria. Dysphagia was highly prevalent in both groups even without UVCP. Biosorption and equilibrium isotherms study of cadmium removal by Nostoc muscorum Meg 1: morphological, physiological and biochemical alterations.

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The health visitors provided oral health education and distributed registration vouchers to mothers of new babies during home visits. This specific papuloerythroderma responded well to the Re-PUVA treatment, which is a combination of etretinate and PUVA photochemotherapy. X-ray changes in the skull bones of children and adolescents with the first-second branchial arches syndrome are analyzed. Leukotriene C4: the major lipoxygenase metabolite of arachidonic acid in dog spleen. To study the expression of Fhit protein in lung cancers and its potential relevance in the diagnosis and prognosis of lung cancers.

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Patients (151 ears) with conductive hearing loss were examined using several methods: otomicroscopy, air- and bone-conduction threshold,pure tone average, speech threshold, speech discrimination, tympanometry and stapedial reflex and tympanoscopy. The findings regarding age, general health and vitality are well in line with previous studies. Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events. The luteal content varies with reproductive state, with the highest zantac 75 mg recall amount found in early luteal phase CL.(ABSTRACT TRUNCATED AT 250 WORDS). Two oligopeptides corresponding to the variable region (4V) and whole domain (4L) of syndecan-4 cytoplasmic domain were synthesized for nuclear magnetic resonance (NMR) studies. With a combination of this azide and BTTPS, a tris(triazolylmethyl)amine-based ligand for Cu(I), we were able to detect newly synthesized cell-surface glycans by flow cytometry using as low as 1 nM of a metabolic precursor. This study proposes a software tool to simulate the possible wavefront motion on the surface of human brain. Multiple firing of motoneurones is produced by cortical stimulation but not by direct activation of descending motor tracts.

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Activated enzymes and oxygen free radicals injure the acinar cell and cause a release of cytokines and vasoactive mediators, attract inflammatory cells and activate the vascular endothelium as well as the expression of adhesion molecules. National sharing of cadaveric renal allografts for perfectly matched kidneys (0 antigen mismatch) has improved outcome in the recipients of these kidneys despite increasing cold storage times. The composition of the HPLC mobile phase was systematically varied in order to select the optimal conditions for separation. The type II TW was located in excitable gaps following reentrant action potentials of short duration. Little is known about potential ethnic differences in stroke incidence. We report zeta potential and aggregation kinetics data on colloidal latex particles immersed in water-alcohol media.

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Reevaluation of the cancer potency factor of toxaphene: recommendations from a peer review panel. A partial neurologic improvement was observed after laminectomy and cysto-peritoneal derivation. The developmental expression and subcellular distribution of the neuron-specific 25-kDa synaptosomal protein (SNAP-25) were investigated by using Northern (RNA) blots, immunoblots, and immunocytochemistry. Modulation of CA-125 tumor marker shedding in ovarian cancer cells by erlotinib or cetuximab. Influence of the calcium antagonist nitrendipine on the hepatotoxic effect of cyclosporine A. The animals from each age group were subdivided into three subgroups. Their association with the vestibule is inconsistent and, thus, we recommend that these structures be renamed the bulbs of the clitoris. We assess reliability and safety of Sugita titanium aneurysm clips for routine clinical use in a large number of operated cases. Generalised smooth-muscle disease with defective muscarinic-receptor lasix water pill dosage function.

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(8) Patients reported confusion about the rules of the program and often did not understand its terms and benefits. (4) The mitosene iminium ion alkylates DNA at both nitrogen and oxygen centers without any apparent antivert 25 mg cost base selectivity. TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice. The aim of this research was to determine the prevalence and etiology of acquired ataxia in Al-Kharga district, New Valley, Egypt. Antigenic regions on the U1 small nuclear ribonucleoprotein (snRNP)-associated 70K polypeptide recognized by human and mouse autoantibodies or by monoclonal antibodies were identified and compared. Previous studies have suggested that ethanol potentiates GABA-mediated responses in the mammalian brain. Biopsies for suspicious calcifications should be followed immediately by specimen radiography to verify their removal. Divergent growth, where larger individuals grow proportionately more than smaller individuals, is seldom observed.

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