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Brethmol (Albuterol)
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Brethmol

Brethmol is an inexpensive drug used to treat asthma and COPD. It is more popular than comparable drugs. It is available in generic and brand versions. Brethmol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Aerocort, Alernyl, Asthamol, Asthasol, Brethmol, Bronkonat, Budesal, Derisone, Efflin, Elkuf, Exporil, Kofnil, Ophyl, Pedex, Pherin, Proventil, Respisol, Salbrom, Salbu, Salcare, Salmaplon, Salsol, Sancoril, Silicof, Somavent, Spasmonyl, Ventirex, Ventorlin, Ventryl, Viburil, Viscodyne, Vospire, Zerfy

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Also known as: Albuterol

Description

Brethmol belongs to a class of drugs known as bronchodilators. Brethmol is indicated for the relief and prevention of airway obstruction (bronchospasm) in patients with asthma and in patients with exercise-induced asthma. Brethmol can also be used in treating patients with emphysema and chronic bronchitis when their symptoms are related to reversible airway obstruction. Albuterol, the active ingredient in Brethmol is a selective beta-adrenergic bronchodilator used to treat severe acute asthma and chronic bronchospasm caused by other pulmonary obstructive disorders that have not responded to other forms of therapy. Generic names of Brethmol are Albuterol, Salbutamol. Brethmol is also known as Albuterol, Salbutamol, Ventorlin, Asthalin, Proventil, ProAir, Salamol, Aerolin.

Dosage

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to ReliOn Brethmol HFA. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.

The albuterol inhalation solution (eg, Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose. Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine. Connect the nebulizer to the face mask or mouthpiece. Use the face mask or mouthpiece to breathe in the medicine. Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone. Clean all the parts of the nebulizer after each use.

The albuterol inhalation aerosol (eg, ProAir® HFA, Proventil® HFA) and albuterol inhalation powder (eg, ProAir® Digihaler™, ProAir® Respiclick®) are used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you or your child use the inhaler to make sure you are using it properly.

To use the inhalation aerosol:

The inhaler should be at room temperature before you use it. Insert the metal canister firmly and fully into the actuator. This actuator should not be used with other inhaled medicines. Remove the cap and look at the mouthpiece to make sure it is clean. Point the inhaler away from your face. Shake the inhaler well and test spray it in the air 3 times for ProAir® HFA or 4 times for Proventil® HFA before using it for the first time or if the inhaler has not been used for more than 2 weeks. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright. Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister. Hold your breath for about 10 seconds, then breathe out slowly. If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler. When you have finished all of your doses, rinse your mouth with water and spit the water out. Clean the inhaler mouthpiece at least once a week with warm running water for 30 seconds, and air dry it completely. If you need to use the inhaler before it is completely dry, shake off the excess water, replace the canister, and spray it 2 times in the air away from the face. Use your regular dose. After using the inhaler, wash the mouthpiece again and dry it completely. If the mouthpiece becomes blocked, washing it will help. The Proventil® HFA inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The counter will turn red when there are only 20 doses left, to remind you to refill your prescription.

To use the inhalation powder:

Take the inhaler from the foil pouch before you use it for the first time. The inhaler provides about 200 inhalations. The dose counter will change to red when there are "20" doses left. Call your doctor or pharmacist for a refill of prescription or medicine. Make sure the cap is closed before using this medicine. Do not open the cap unless you are going to use it. Hold the inhaler upright as you open the cap fully until you hear a "click". Your inhaler is now ready to use. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it. Breathe in through your mouth as deeply as you can until you have taken a full deep breath. Do not block the vent above the mouthpiece with your lips or fingers. Hold your breath for about 10 seconds or as long as you comfortably can. Remove the inhaler from your mouth and check the dose counter to make sure you received the medicine. Close the cap firmly over the mouthpiece after using the inhaler. Always close the cap after each use. If you are supposed to use more than one puff, repeat these steps for the second puff, starting with opening the cap fully. Do not use a spacer or volume holding chamber together with the ProAir® Digihaler™. Keep the inhaler clean and dry at all times. Do not wash or put any part of the inhaler in water. Replace the ProAir® Digihaler™ if it has been washed or placed in water. If you need to clean the mouthpiece, wipe it gently with a dry cloth or tissue.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation aerosol dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation powder dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation solution dosage form (used with a nebulizer): For prevention of bronchospasm: Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed. Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed. Children younger than 2 years of age—Use and dose must be determined by your child's doctor.

Overdose

If you overdose Brethmol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store unopened vials of this medicine at room temperature, away from heat and direct light. Do not freeze. An open vial of medicine must be used right away.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store Proventil® HFA inhaler with the mouthpiece down.

Throw away the ProAir® Digihaler™ or ProAir® Respiclick® 13 months after opening the foil pouch, when the dose counter reaches "0", or after the expiration date, whichever comes first.

Detailed Brethmol dosage information

Side effects

The most common side effects associated with Brethmol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of Proventil® HFA in the geriatric population. However, elderly patients are more likely to have age-related heart problems, which may require caution in the dose for patients receiving Proventil® HFA.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ProAir® Digihaler™, ProAir® HFA, and ProAir® Respiclick® in geriatric patients. However, elderly patients are more likely to have age-related heart, kidney, or liver problems, which may require caution and an adjustment in the dose for patients receiving ProAir® Digihaler™, ProAir® HFA, and ProAir® Respiclick®.

No information is available on the relationship of age to the effects of albuterol inhalation solution (eg, Accuneb®) in geriatric patients.

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Transmission of gamma G antibodies from maternal to fetal circulation in the mouse. On admission, the physical examination showed a tough and fixed tumor, with no inflammatory signs nor vascular characteristics. It is unclear, however, whether and how the underlying neural system is disrupted in these subjects. Spermine switches a Neurospora VS ribozyme from slow Cis cleavage to fast trans cleavage. Co-culture with mercuric chloride and PHA showed a statistically significant dose-dependant release of serotonin, but no differences between the three clinical groups could be detected. Pediatric Extracorporeal Life Support Organization Registry International Report 2016. Transformed fibroblasts and fetal lung tissues expressed more TN mRNA with an extra sequence encoding the sixth FN type III repeat than did normal cells and adult tissues. The potency of HR1 toxoid in terms of the immunizing unit (ImU) appeared to be related to the antigen and aluminum contents.

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With this review, we aim to summarize the current epidemiological evidence on the effect of traffic-related air pollution on lung function in children and adolescents. We investigated the mechanism by which endothelial cells (ECs) resist various forms of physical stress using an experimental system consisting of rat arterial EC sheets. Mutational Analysis of Mitochondrial tRNA Genes in Patients with Asthma. Stabilization and eventual resolution was achieved using intravenous and topical steroids followed by hyperbaric oxygen therapy, again highlighting the benefits of multimodality therapy in the setting of pyoderma gangrenosum. We report the first case, to our knowledge, of verrucous carcinoma occurring in a lesion of oral lichen planus. To assess race disparities in WT epidemiology, the Tennessee Cancer Registry (TCR) was queried for all in-state patients less than 20 y of age and registered between 1999 and 2008. The TCCC is a valuable example of how IOM initiatives can improve the healthcare system.

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To investigate this phenomenon, we measured the average of three P wave amplitudes (PWA) and calculated slew rates from telemetered printouts acquired from Pacesetter pacemakers in 32 patients. Although many studies have indicated that obesity seemed not to be directly associated with mortality, metabolic abnormalities including hypertriglyceridemia, a low level of high-density lipoprotein cholesterol, glucose intolerance and visceral fat accumulation are common in HD patients with over-nutrition. If trial quality was unclear, or if there were missing outcome data, trialists were contacted in an attempt to get further information. Rapid diagnosis based on inclusions in the peripheral blood smear. Communication, family adaptability and cohesion were examined separately for adolescents and for parents, and significant relationships were found. We treated a patient with large multiple chondrosarcomas derived from multiple cartilaginous exostoses. A new disaccharidase inhibitor, AO-128, showed 190-3900-fold more potent inhibition of purified rat small intestine sucrase-isomaltase (S-1) complex and 23-33-fold more potent inhibition of semipurified porcine small intestine disaccharidases than acarbose. Prior mannitol and furosemide infusion in a model of ischemic acute renal failure. Upon admission, the patient had a head CT followed by an MRI examination, which revealed cranial hematomas localized bilaterally in the area of the frontal, temporal and parietal lobes, spreading from the cranial vault to the skull base. The use of imaging (computed tomography and magnetic resonance imaging added to clinical findings and standard guidelines) are studied in the treatment planning of external irradiation and brachytherapy in carcinoma of the cervix.

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We analysed CAPN10 UCSNP-44, -43, -19, and -63 allelic distribution in 218 unrelated laryngeal cancer patients what is the cost of rocaltrol and 606 controls from the general population. In this review, we describe the dermoscopic features of the most important nail disorders, looking at the different areas of the nail. Immunosuppression is a critical effect associated with exposure to PFCs, as it has been reported to reduce antibody responses to vaccination in children. The Kaplan-Meier method was employed to analyze overall survival. Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall cell lung cancer.

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Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells. This insufficiently efficient autophagy leads to an accumulation of p62 and NBR1, which are robust markers of protein aggregations. Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature. Mitomycin C induces apoptosis in human epidural scar fibroblasts after surgical decompression for spinal cord injury. Effects biaxin antibiotic used to treat of plaster-of-paris implants in surgical defects of mandibular alveolar processes of dogs. The inflammatory and immune response to Helicobacter pylori infection.

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