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Bolodol (Tramadol)

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Bolodol is a narcotic-like pain relieving oral medicine that is used as a treatment for moderate to severe pain in adults. This medication must be prescribed by a doctor and is available by prescription only.

Other names for this medication:
Anatram, Arodol, Bestodol, Bolodol, Cadol, Contramal, Cradol, Doleira, Dolstar, Kevtram, Mandol, Meridol, Moludol, Neutram, Nictram, Nopidol, Oshdol, Painadol, Paxmax, Postadol, Ramax, Sayodol, Servodol, Simol, Traceta, Tragesic, Tramak, Tramasol, Trambax, Tramdop, Trampar, Trofel, Trydol, Typhon, Ultraspas, Ultrax, Unidol, Urgendol, Vardol

Similar Products:
Clarinex, Lunesta, Elavil, Fosamax, Arimidex, Nexium, Microzide, Aurogra, Fulvicin

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Bolodol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Bolodol ER.

Never share Bolodol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Bolodol ER.

Bolodol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Bolodol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Bolodol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Bolodol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Bolodol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bolodol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Bolodol ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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The clinical significance of visceral fat accumulation in childhood obesity has remained controversial. Presentation and analysis of the results of clinical trials in cardiovascular disease. The Km was 0.5 mg/ml for hydrolysis of hyaluronic acid at 37 degrees C. Vocal interactions in many birds are characterized by imitation or the matching of vocalizations whereby one individual makes its vocalizations more similar to those of a conspecific. Pulmonary function parameters as prognostic factors in advanced non-small cell lung cancer. Sixty-one constitutively expressed cDNA sequences were identified and characterized. Increased mortality has been observed when HIV-infected patients were treated with pyrimethamine (Pyr) as prophylaxis for toxoplasmic encephalitis, suggesting that Pyr might possess immunosuppressive activity.

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Thirty right-handed novice participants performed the tasks with five tool-grasping hand postures at two computer monitor angles that simulated reaching an organ during laparoscopic surgery. In this article, the authors report the successful treatment of severe palmoplantar hyperkeratotic psoriasis with etanercept and alitretinoin combination therapy. Conservative scoring and exclusion of the phenomenon of interest in linear enamel hypoplasia studies. Both the original and structured CT results on liver and spleen injuries were transferred into OIS grades. The aims of this study were (i) to assess the protection of pEC against xenogeneic NK-mediated cytotoxicity afforded by the stable expression of HLA-E single chain trimers (SCT) composed of a canonical HLA-E binding peptide antigen, VMAPRTLIL, the mature human beta2-microglobulin, and the mature HLA-E heavy chain, and (ii) to test whether HLA-E expression on pEC and porcine lymphoblastoid cells affects the adhesion of human NK cells. The absence of metabolic ageing may be explained by the very high rate of cell renewal during homeostasis and alternating phases of degrowth and growth during which tissues are renewed. Expression characteristics of structural proteins reveal that AVMs and CMs have different immunohistological properties. Proton pump inhibitors in the management of gastroesophageal reflux disease. The morphologic, radiologic, and genomic changes during CLG were related to each other in pneumonectomized mice. Proceedings from the Annual Meeting of the American Academy of Orthopaedic Surgeons, March 17-26, 2006, Chicago, Illinois, USA.

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While recent research has addressed the interests and preferences of doctoral trainees for non-academic careers, the strategies and resources that trainees use to prepare for a broad job market (non-academic) are poorly understood. Considerable variation of plasma levonorgestrel concentrations was observed between subjects, but within each subject, the plasma level of levonorgestrel was very stable with time. Several components of the diversity of plant communities, such as species richness, species composition, number of functional groups and functional composition, have been shown to directly affect the performance of exotic species. IPA, on the other hand, led to a marked dose-related increase in tryptophan, 5-OH-TRP, serotonin and 5-OH-indoleacetic acid, and was also active on N-acetylserotonin and melatonin synthesis in both phases. Results of comparative bacteriologic examination of the urine and the kidney tissue in nephrolithiasis. Socialising with higher-status individuals can be hypothesised to exert opposing influences on the mental health of the ego.

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On the diagnosis of Trichomonas invasion on dry smears by the method of luminescent microscopy. Surgical removal of an atrial septal occluder device embolized to the main pulmonary artery. A total of 153 breast cancer patients, who were treated with postoperative 5-fluorouracil-based chemotherapies, were randomly selected. The clinical spectrum of CHS is broader than previously recognised. The group of 13 carcinoma patients had a range of two to five endoscopic procedures with one to four negative biopsies and a 6 week to 9 month delay in histologic confirmation of cancer. The heart rate response was larger to the third heelstick as compared to the first two procedures. Timing of in vivo maturation of equine preovulatory oocytes and competence for in vitro maturation of immature oocytes collected simultaneously. Genomic studies of these marks using model systems are limited, particularly with array-based tools, because the standard method of detecting DNA methylation cannot distinguish between 5-mC and 5-hmC and most methods have been developed to only survey the human genome. Use of this diagnostic agent in the neutralization test permitted a highly specific detection of the pancreatic antigen. UV-light also induces the release of the proopiomelanocortin (POMC)-derived peptide, alpha-melanocyte-stimulating hormone (alpha MSH), from keratinocytes, and upregulates the expression of POMC mRNA.

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The replacement of animal testing for endpoints such as reproductive toxicity is a long-term goal. Secondary comparisons include comparison of different upright positions and the supine position. Concerning the initial condition there was no significant difference between the three therapy groups of the study. Half a year later the collapsed subgroups were found to have a higher frequency of attention problems at school than the other three subgroups. Hepatic drug metabolizing enzymes induced by clofibrate in rasH2 mice. Overexpression of myristoylated alanine-rich C-kinase substrate enhances activation of phospholipase D by protein kinase C in SK-N-MC human neuroblastoma cells. And a parametric robot bone-grinding plan and high level control have been developed for plane grinding for cervical top endplate and tail endplate grinding by a cylindrical grinding drill and spherical grinding for two articular surfaces of bones by a ball grinding drill. In picture naming, participants were more impaired in retrieving compounds than matched simple nouns and showed different error patterns.

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The emission images of band heads of nitrogen molecule and nitrogen molecule ion extended toward the axial/radial directions of the plasma at larger microwave powers supplied to the MIP, thus elevating the number density of the excited species of nitrogen, which would activate any chemical reaction on the iron substrate. Reduced positive incentive values from stimuli may lead adolescents to pursue new appetitive reinforcers through drug use and other risk-taking behaviors, with their relative insensitivity to drugs supporting comparatively greater per occasion use. The surgeons were confident and accurate in diagnosing a full-thickness tear of the supraspinatus, but they underestimated its coronal and sagittal extent and its reducibility to the greater tuberosity. Non-Angled Intercostal Percutaneous Access Under Full Expiration: Safety Is Not an Issue Anymore. Platelet aggregation in vitro with a variety of inducers in the elderly showed age-dependent gain.

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A Giant Glitch in the Energetic 69 Millisecond X-Ray Pulsar AXS J161730-505505. Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. However, it is now possible to detect circulating cerebral microemboli by means of transcranial Doppler ultrasound. After 12 days, jejunal segments were removed and processed for morphometric analysis of mucosal architecture and quantitative histochemical determinations of the apparent Km- and Vmax-values of lactase/beta-glucosidase and neutral alpha-glucosidase at constant basal and apical measuring positions along the villi. The changes in renal haemodynamics produced by intravenously infused saralasin (dose 0.01-10 microgram kg-1 min-1) were assessed by clearance methods. When a group of poor responders was compared to patients with normal stimulation characteristics, no significant difference was found in either IGF or IGFBP levels in the FF. New therapeutic approaches to combat arterial thrombosis: better drugs for old targets, novel targets, and future prospects. Serotonin and 5-hydroxy indole acetic acid in infantile hydrocephalus. However, there are still many missing pieces and too little is known about the compartment-specific repertoire and concentration of numerous metabolites, substrates, enzymes, and transporters as well as rate constants and enzyme kinetic patterns. Although the addition-type polymers generally had a higher filler content than the condensation types, they had a lower opacity.

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CNI-H0294, a nuclear importation inhibitor of the human immunodeficiency virus type 1 genome, abrogates virus replication in infected activated peripheral blood mononuclear cells. Beat-to-beat hemodynamic functions were determined noninvasively by photo-plethysmography and impedance cardiography. The responses were modeled in terms of a dispersive capacitance in series with two RC circuits (series and parallel). Keratinocytes and Langerhans cells constitutively express the lymphocyte function-associated antigen 3. The GFI scores were compared in subjects with and without vocal cord findings. In animals, the Argonaute superfamily segregates into two clades. 3) THERAPY: treatment should take the initial venous thrombosis into account, especially with regards to the choice of thrombolytic agents and surgical clipping of the IVC. Polytetrafluoroethylene and bovine mesenterial vein grafts for hemodialysis access: a comparative study. Many nursing conferences include research reports in the form of oral reports, symposia discussions, and poster presentations.

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We report that there are extensive interactions between TMCG and DPPC involving the perturbation of the thermotropic gel to liquid crystalline phase transition of the phospholipid, the decrease of bilayer thickness and the promotion of interdigitated gel phase, together with an increase of the hydrogen bonding pattern of the interfacial region of the bilayer. We report a case of hepatocellular carcinoma that entirely involved the common bile duct, the hepatic involvement was undiscernible at operation or ultrasonography. Targeted interventions initiated perinatally could possibly prevent some cases of abusive head trauma. Experimental study on the relationship between the ratio of length to width of slender narrow pedicle and random flap survival area in pig. The treatment of position anomalies caused by supernumerary teeth of missing tooth germ. Effect of ionizing radiation on antibody and unspecific gamma-globulin synthesis in mouse spleen cells.

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To investigate the association between sex and revisits to the emergency department (ED), and readmissions after MI. In addition, we demonstrate that Dicer proteins (DCLs) regulate QDE-2 posttranscriptionally, suggesting a role for DCLs or siRNA in QDE-2 accumulation. Jump-grafts were constructed for recipients with hepatic artery thrombosis, and double donor arteries were joined to the bifurcation of the recipient hepatic artery. A new method of staining the keratin filament matrix allowing a visualization of the filaments in cross section of hair fibres has been developed. Surprisingly, in nearly all cases with infectious complications, numerous plasma cells could be found. D2 lymph node dissection plus PAND may improve the overall survival for gastric cancer patients in N3 stage. Weekly paclitaxel and carboplatin (PC-W) for patients with primary advanced ovarian cancer: results of a multicenter phase-II study of the NOGGO. In presenting the case of a 61-year-old man with a primary squamous carcinoma in a bladder diverticulum, the authors stress the usefulness of applying all the available modalities of imaging, since it has been found that a bladder diverticulum may harbor a neoplasm more often than a normal bladder. Because it is difficult to identify morphologically the Japanese forms of Fasciola, additional taxonomic criteria are required.

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Re: pediatric urology fellowship training: are we teaching what they need to learn?. Gene expression of taurine transporter and taurine biosynthetic enzymes in brain of rats with acute or chronic hyperosmotic plasma. Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function. Inhibition of thrombin-induced tissue-type plasminogen activator release by agents which increase intracellular cyclic AMP. When concerning state estimate of the dual-rate system with time delay, the state augmentation method is employed with lower computational load than that of the conventional one.

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A new design ankle replacement has been suggested recently which allows multiaxial motion at the ankle while maintaining congruency throughout the arc of motion. The present study was the first to examine these increases for binge eating. No nucleotide change at the 94th codon of inhA was detected in any of the 24 INH-resistant isolates analyzed in this study. We established a novel murine model of pharyngeal candidiasis maintaining stable yeast population and local symptoms characteristic of pharyngeal thrush. Further tasks of the press and scientific information in the field of stomatology. Metachronous metastasis of renal cell carcinoma to the contralateral adrenal gland is very rare. IgG2 activates the classical pathway only at high epitope density and at equivalence or antibody excess. When the hormonal concentrations of the young and aged groups were compared in the various experiments, the older mice consistently exhibited higher levels of gonadotropin and lower levels of prolactin than those of the younger mice. Many of the regions that are normal in uncomplicated alcoholics are damaged in those with the Wernicke-Korsakoff syndrome.

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To date, relatively little evidence has been published as to what represents an effective and efficient way to improve quality of care and safety in hospitals. CO2 laser lesions were created at varying power densities on the exteriorized canine bladders. The recycling experiments showed that counterflow improves separation and the steady-state patterns are dependent on the fluid layer thickness in the separation cell but, with a given gap, essentially independent of applied current and recycling pump rate. Longevity of exercising male rats: effect of an antioxidant supplemented diet. Psychiatric care patients commonly end up outside the labour force. Plastic surgical reconstruction of the perineum is often required after abdominoperineal excision of the rectum. Regulation of hsrM(nonB) expression in spoOA mutants and effects on permissiveness for phi15 and phi105 phages.

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In those institutions where such strains are endemic, the class concept of disc testing may not be applicable. An attempt to vaccinate owl monkeys (Aotus trivirgatus) against falciparum malaria. Although discovered as IFN-regulated factors, deletions of these genes cause leukemias in experimental models and in human patients. The remarkably high rate of unemployment zopiclone 3.75mg tablets in this young, first-episode sample, and the evidence of associations between unemployment, greater symptomatology, and poorer functioning, argue for further research and development on supported employment programs for such patients. The specific anti-GPL serum is a useful tool for the identification and classification of atypical mycobacteria and for the study of the fate of the organisms and their superficies during phagocytosis.

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The global safety of the treatment was evaluated using a visual analog scale between 0 (intolerable) and 10 (completely safe). A segmentectomy of the third and fourth portions of the duodenum biaxin type of antibiotic was performed. When administered in the absence of a carrier and adjuvant this peptide, which corresponds to a linear epitope located at the C-terminus of histone H3, was not immunogenic. Thus, the same gene encodes both a growth factor and its direct antagonist. We also show that Id4 expression decreases prematurely when the precursor cells are induced to differentiate by mitogen withdrawal. Intimacy as an interpersonal process: the importance of self-disclosure, partner disclosure, and perceived partner responsiveness in interpersonal exchanges.

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: The aim of this study was to evaluate the reproductive outcome of women with history of infertility or recurrent miscarriage following hysteroscopic septum resection. Hypothesis 2 was rejected for these three halophytes, as the branch density of 1st- and 2nd-order laterals appears to be controlled by other factors than length of individual laterals. Scanning electron micrographs showed the accurate structure of the cephalic region, described here in detail. Clinical algorithms for the treatment of dizziness, headaches and vomiting would improve the selection of candidates for brain imaging. A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene.

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Hepato-specific regulatory (promoter/enhancer) DNA sequences were used for targeting the expression of onc genes, such as murine c-myc and Simian Virus 40 T Antigen, to hepatocytes of transgenic mice which subsequently developed hepatocellular carcinomas after a variable period of time (depending on the type of onc gene employed). Agrobacterium tumefaciens VirD2 protein is one of the key elements of Agrobacterium-mediated plant transformation, a process of transfer of T-DNA sequence from the Agrobacterium tumour inducing plasmid into the nucleus of infected plant cells and its integration into the host genome. We describe a case in a 4-year-old child diagnosed as triphalangism foot with no other obvious visible anomaly. Ribosomal alteration-derived signals for cytokine induction in mucosal and systemic inflammation: noncanonical pathways by ribosomal inactivation. Infections are regarded as a major complication and an important cause of death in cirrhotics. Animal experiment methods for the testing of fibrinolytic and antifibrinolytic agents.

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The metabolism of uracil administered exogenously as UFT was not influenced by 5-FU or its metabolites derived from FT. Two-third-resections of the proximal or distal small bowel with and without cleocin drug class artificial valves were performed in rats. Participants would want to know the true status of their health and plan ahead in consultation with family members to reduce the burden on the family and suffering for themselves. Previous studies have suggested that the N-terminal domain of ICAM-1 is critical for binding of the major group rhinoviruses. In the view of the authors, two essential surgical techniques should be used : polar nephrectomy and resertion of the diverticular protrusion with closure of the neck. A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization. Rabbit immunoglobulin lambda chains: amino acid sequences of variable- and constant-region peptides from normal and allotype-suppressed rabbits. This study investigates aliskiren, the first in a new antihypertensive class called renin inhibitors. Electrolyte abnormalities underlying lethal and ventricular arrhythmias.

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The results showed a differentiation-status-related pattern in which a well-differentiated cell line (WRO) expressed all the four genes, in contrast to an anaplastic cell line (ARO) that expressed TTF-1 and reduced levels of TSHR, but no Tg or PAX-8 genes. This data was analyzed to determine inpatient and outpatient activity by specialty and compared with the nonepileptic population. However, effective targeted cancer therapies require the identification of key molecules in the pathogenesis of cancer. Cytoskeletal proteins (i.e., cytokeratins, vimentin, actin, and desmin) are normally present in the placental chorionic villi and are related to the maintenance of the villous shape, and to the ability of the villi to contract and permit a normal blood flow. Renin-angiotensin-system (RAS) is an enzymatic cascade that plays a pivotal role in the development of arterial hypertension, kidney disease and cardiovascular disease.

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The hyperbranched cationic glycogen derivatives conjugated with DMAPA and AEPZ residues were synthesized. This paper describes the method development and optimisation of the derivitization step, the chromatographic conditions and mass spectrometry detection, together with a summary of the validation of the method. In addition to the exact homologies tabulated, motifs of matching sequences are repeated frequently in these domains. Creative response to alternative medicine: clients of a modern Finnish healer in a northwestern Ontario city. The second part of this reflex arc, from the bulbar vasopressor centre to the peripheral effector sites, can be explored directly by studying the hemodynamic response to an increase in arterial CO2 levels. Mab 113F4, a monoclonal antibody recognizing an antigen in the outer synaptic layer of the chick neural retina, also recognizes an antigen appearing in all three germ layers of the gastrulating chick embryo. In cells deficient in micro1A-adaptin the remaining AP-1 adaptins do not bind to the TGN. Results of radiohypophysectomy for advanced cancer of breast in relation to sex chromatin determination. Nearctic migrants also showed evidence of an abundance of rare nonsynonymous (amino acid-altering) polymorphisms, a pattern suggesting that slightly deleterious polymorphisms drifted to high frequencies during a bottleneck and are now being eliminated by selection.

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Decreased mineralization in hemodialysis patients after subtotal parathyroidectomy. This lack of methodological detail affects outcomes, generalizability, and validity of research involving acupuncture. The magneto-optical signal can be recorded in a confocal reflection geometry with an accurate selection of the polarization. CRANIAL MORPHOLOGY OF DOMESTIC AND WILD CANIDS: THE INFLUENCE OF DEVELOPMENT ON MORPHOLOGICAL CHANGE. Detection of hybrids in natural populations of the Anopheles gambiae complex by the rDNA-based, PCR method.

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One patient was managed with surgical evacuation of the hematoma were in the others conservative management initiated but failed. Clinically, LOS and EOS subjects were similar, except that EOS subjects had more negative symptom scores, tended to have more delusions of guilt/sin and of being controlled and more formal thought disorder, and had significantly poorer instrumental activities of daily living. Depression severity and quality of life of qualified and unqualified cordarone 200 mg cost patients with a mood disorder for a research study targeting anhedonia in a clinical sample. Threshold differences for naloxone and naltrexone in the hypothalamus and midbrain using fixed ratio brain self-stimulation in rats. AIDS-defining opportunistic illnesses in the HAART era in New York City. It is also involved in the occurrence and development of the tumor. Measurements were performed on three groups of eight eyes, each with different surface characteristics: intact epithelium, mechanically abraded epithelium, and 90 microm excimer laser keratectomy. To assess the effects of dynamic exercise therapy in improving joint mobility, muscle strength, aerobic capacity and daily functioning in patients with rheumatoid arthritis (RA). A total of 56 infants and children were studied: 2 had pneumonia, 11 had an exacerbation of pulmonary signs and symptoms with their underlying cardiac or pulmonary disease, and 43 had bronchiolitis.

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