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Bludol (Tramadol)

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Bludol is an oral medication that is used to help relieve ongoing moderate to moderately severe pain. Bludol is similar to opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain.

Other names for this medication:
Admadol, Atdol, Combitram, Cosdol, Damol, Dolmeri, Dolodol, Domaspas, Gemodol, Kevtram, Mandol, Meridol, Moludol, Nosdol, Opiran, Paintrol, Paxmax, Pentazen, Postadol, Ramadol, Ramcet, Rimol, Ryzolt, Sayodol, Simol, Soztram, Spasteez, Supridol, Tandam, Taramol, Tolydol, Tradol, Tramafen, Tramagesic, Tramak, Tramatas, Tramazac, Tramazol, Tramest, Tramospas, Tramot, Tranzat, Trazac, Tromar, Trydol, Ultraspas, Ultrax, Vegadol

Similar Products:
Nimotop, Reminyl, Alprostadil, Aricept, Levaquin

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Bludol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Bludol ER.

Never share Bludol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Bludol ER.

Bludol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Bludol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Bludol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Bludol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Bludol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Bludol dosage information

Side effects

The most common side effects associated with Bludol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Bludol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Bludol should not be given to a child younger than 12 years old. Bludol ER should not be given to anyone younger than 18 years old.

Do not give Bludol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Bludol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Bludol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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To provide quantitative information on the internal dimensions and cortical shell thicknesses of the middle and lower cervical pedicles. Rats exhibit neurological and cognitive impairments, which can be partially reversed by thiamine administration, enabling the study of mechanisms of neurodegeneration as well as neuroprotection. 3 NEA pills contained 50 mcg of ethinyl estradiol combined with 1, 3, and 4 mg of NEA. The diagnosis of visceral leishmaniasis (Kala Azar) was suspected. When it suppresses the stabilization of the encounter complexes between reagents, sonication hinders the reaction but accelerates it when it perturbs the hydrophobic stabilization of the ground state of a reagent. Ex vivo studies with rabbit cornea were performed using side-by-side diffusion chambers to evaluate the apparent permeability coefficients and acute tissue tolerance of the CPP candidates. We determined chemosensitivity by infusing 0.1 N hydrochloric acid into the mid-oesophagus for 10 min at 10 ml/min after a 2-min infusion of normal saline at a similar rate. Kidney weight, kidney weight per body weight, renal cyst area, renal Ki67 expression, and serum urea nitrogen were significantly decreased either in the PAS or OCT/PAS group, compared with vehicle. Genetic characterization and transovarial transmission of a typhus-like rickettsia found in cat fleas. The ability of reacting with the mAb against two molecules disappeared for all the LPPG positive ones when were treated with meta-periodate, and only three reacted against the glycoproteins.

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This first-in-human clinical experience has demonstrated the safety and feasibility of using the new version of the EMBOL-X intra-aortic filter during either cardiac surgery or transaortic transcatheter aortic valve implantation. Previously we raised a rabbit monospecific antibody (C2003) against a synthetic peptide derived from a sequence within the C-terminal portion of the reverse transcriptase (RT) of the human immunodeficiency virus type 1 (HIV-1). Cell and tissue targeting of nucleic acids for cancer gene therapy. Transpiration was sensitively reduced by KNO3, ABA, or buffers adjusted to pH 6.7-7.0 (compared with buffers adjusted to pH 5.0) alone. Forty-nine patients were operated on (minimal follow-up of 1 year). Detection of Avian bornavirus in multiple tissues of infected psittacine birds using real-time reverse transcription polymerase chain reaction.

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Big endothelin-1 (ET-1) injected systemically in vivo induces a long-lasting pressor response, in contrast to its active metabolite ET-1, which alters in a biphasic fashion the mean arterial pressure (MAP) of the anesthetized rabbit. Sphingosine 1-phosphate (S1P), a G-coupled protein receptor (GPCR) agonist, has been previously shown to promote endothelial cell tight junction formation and prevent monocyte chemotaxis. Nebivolol is a new cardioselective beta-blocking agent possessing vasodilatory properties involving the endothelium. Using ordinary least squares and logistic regression we estimated associations between resident well-being and organizational characteristics, transition experiences, and social relationships, controlling for gender, age, education, and physical functioning. The use of contrast agents with low rather than high osmolality during cardiac angiography reduces the risk of moderate, but not of severe, adverse reactions to the agent used.

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Women, children, the elderly, and those with common medical conditions are frequently excluded from RCTs. The nitrophenols were analyzed by reverse-phase high performance liquid chromatography (HPLC) and did not require any derivatization. In cultured binucleate lymphocytes of two age groups of men, the X chromosome showed significantly higher mean frequencies of hyperdiploidy, hypodiploidy and reciprocal gain and loss than the Y chromosome. High physical fitness level, good mental health, standard body weight are more common in regular exercise group. The relationship of root canal enlargement to finger-spreader induced vertical root fracture. A 60-year-old woman with vulvar carcinoma was admitted to our hospital for further examination of an abnormal shadow on chest computed tomography (CT). catawbiense (Cata.), and from leaves of cold acclimated plants of the less hardy, non-thermonastic R. Results of the anti-inflammatory treatment of women with a history of ascending gonorrhea. I describe the relationship between a suite of phenotypic characters (behavioral posture and the pattern of wing pigmentation) and one function of these characters (thermoregulatory performance) for two groups of butterflies in the family Pieridae, focusing on how behavior and wing pattern interact to affect specific aspects of thermoregulation. There was no effect of treatment on the locomotor response of rats to 1.0, 1.5 or 2.0 mg/kg d-amphetamine IP.

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Predator evasion in Daphnia: the adaptive value of aggregation associated with attack abatement. Reports concerning medication discrepancies in dental records indicate that the concept of interprofessional collaboration between the dental team and pharmacists should be considered at all educational levels in dentistry and pharmacy. The space in which the young crystal develops is delimited by a membrane. We searched MEDLINE, BIOSIS, EMBASE, Global Health, SCOPUS, and Cochrane Library from inception to January 2016. The polymeric derivatives of vitamin E stimulated the regenerative process as a consequence of the antiaging effect in the local area of application. The cytokine Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) regulates proliferation, differentiation, and apoptosis during myelopoiesis and erythropoiesis. They were the food preparing area, bedroom, play area, and the area surrounding the house.

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Monitoring urban growth and land cover change will enable better management of this complex urban area by the Greater Istanbul Metropolitan Municipality (GIMM). This study deals with an automated data analysis strategy to pinpoint potential unknown compounds in full scan mass spectrometry (MS) experiments. These antigenic differences were confirmed after preabsorption of the antibodies with serial dilutions of extracts of T. Variation during the menstrual cycle of immune cell populations in human endometrium. Gross-total resection is a critical factor in achieving seizure freedom. In the context of cancer treatment, it involves breaking tolerance to a cancer-specific self-antigen and/or enhancing the existing anti-tumor immune response, be it specific or not. Furthermore they are, impulsivity, BD and suicide behavior, associated with serotonergic function, at least partially, under genetic determinism and somewhat associated with the serotonin transporter gene polymorphism, the 5-HTTLPR. The sister of the proband had persistently strongly positive LE cell preparations for more than a decade and had joint pains while taking sulfa drugs.

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MRA revealed an aberrant right subclavian artery and aplasia of the bilateral posterior communicating arteries composing the circle of Willis. The results support the supposition that the amount of magnesium in elastic fibres is sufficient for histochemical detection. We have examined the practical feasibility of this technique and report on testing the ability of HD to support keratinocyte growth and epithelium formation in vitro, at the air-liquid interface (ALI), and in vivo, after grafting to full-thickness wounds created on the backs of athymic (Swiss Nu/Nu) mice. An adaptive sampling design is one in which the procedure for selecting sites or units to include in the sample can depend on values of the variable of interest observed during the survey. The efficacy of post-anaesthesia care units (PACUs) is therefore important to facilitate return to normal functions. Supervision and guidance of the orthodontic patient by the general dentist.

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The determination of specific IgE (sIgE) against allergenic components fixed in a solid support that is provided as a microarray of high capacity and allows a more precise evaluation in the food allergy diagnosis. Social provisions in adulthood: concept and measurement in close relationships. The findings of the present study showed comparable efficacy and safety of the generic and innovator versions of imatinib in the treatment of patients with chronic myeloid leukemia. We also discuss several evolving novel and innovative genetic immunotherapy approaches for patients with stage IV disease. Lactoferricin is a bioactive peptide fragment (3196 Da) derived from lactoferrin (80 kDa) that contains the bactericidal domain and the lymphocyte receptor-binding domain of lactoferrin. Determination of the bacteriostatic action of the blood in tuberculosis patients. The main objective of those interviews was to check the relation between status/organisation of self-reported risk management and both operator (private, public, NPO) and size of hospital. Conversely, volatile anesthetics decrease systemic oxygen consumption and peripherally inhibit skeletal muscle strength, which might limit maximum intensity despite central activation. The addition of Hantzsch ester as an initiator improves the efficiency of the reaction. This paper presents the results of a national pilot audit of IC services focusing particularly on clinical governance issues.

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The tumor was tightly adhered to the cord surface and successfully removed microsurgically. Cold-active chemoorganotrophic bacteria from permanently ice-covered Lake Hoare, McMurdo Dry Valleys, Antarctica. Genes of insecticidal crystal proteins with dual specificity in Bacillus thuringiensis strains, isolated in the Crimea territory. To initiate fertilization, mouse sperm bind to Ser- (O-) linked oligosaccharides located at the sperm combining site of zona pellucida glycoprotein mZP3. Androgen replacement to castrated animals allowed for the initiation of PBP expression, although its onset was delayed. To clarify the role of the D-stem structure, we tested four mutant transcripts, in which tertiary base pairs were disrupted.

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At the current stage of research, randomised evidence supporting the clinical use of anticonvulsants to treat alcohol dependence is insufficient. A compound composite odontome and a vital homogenous togth transplant in an eight-year-old boy. To better priority setting as well as reporting the magnitude of avoidable DALYs rather than the percentage of avoidable burden, PIF should be applied to updated and revised burden of CVDs. Resistance testing is recommended to help guide the choice of new regimens after treatment failure and for guiding therapy for pregnant women. However, the percentage of impoverished people who made direct payments for services increased. A computer-assisted 13C-NMR-based analysis, methylation analysis, and selective cleavage with anhydrous vermox alcohol hydrogen fluoride and dilute hydrochloric acid were applied for structural elucidation of the polysaccharide and the following structure was established:----2)-beta-D-Glcp-(1----6)-alpha-D-GlcpNAc-(1----3)- alpha-L-QuipNAc-(1----3)-beta-D-GlcpNAc-(1----. The combinations of targeted treatments against this pathway, blocking multiple different steps, are under preliminary investigation. Typical acceptance criteria for analytical methods are not chosen with regard to the concept of method suitability and are commonly based on ad-hoc rules. Skin, mucosa and bone incidents and accidents in the course of chemotherapy by means of intraarterial infusions against maxillo-facial cancers.

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We present two cases of EH within infundibular type follicular cysts, a rare finding only once otherwise reported in 1978. Exposure to violence was further divided according to whether violence was experienced as a victim or as a witness. Because the data on the antigenic phenotype of mucoepidermoid carcinoma (MEC) are incomplete and somewhat disparate, 45 MECs were evaluated immunohistochemically for low- and high-molecular-weight keratins, vimentin, glial fibrillary acidic protein, smooth muscle actin, and S-100 protein. We report a rare case of primary aortoduodenal dose of zithromax in children fistula (ADF) secondary to a Coxiella burnetii (Q fever) infection in a patient with an abdominal aortic aneurysm. aureus infective endocarditis, according to Duke criteria and examined by transthoracic and transesophageal echocardiography. The nutritional consequences of premature birth: improved care has clearly decreased perinatal mortality. This study suggests dogs with heart disease, when anesthetized by trained personnel and carefully monitored during routine dental procedures, are not at significantly increased risk for anesthetic complications. Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template.

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Fever is a frequent symptom of consultation in Pediatric Emergency Department. However, in intermediary cases, the decision to make a systematic nerve exploration during the osteosynthesis procedure (aimed at early mobilization) is based on the fact that recovery was achieved in 23 cases in which initial exploration of a continuous nerve has been performed. The nucleus contains exclusively alpha while the cytoplasm contains both forms. We report a multicenter experience using tubularized incised plate urethroplasty for proximal hypospadias. Normoandrogenaemic, oligomenorrhoeic women with PCOS are metabolically similar to control women with significantly fewer metabolic features than PCOS women who are also hyperandrogenaemic. Moreover, age-related changes in the prevalence of diastolic heart sounds and measurements of systolic time intervals in an asymptomatic population have not been studied in continuous recordings. Possibility of the use of Solanum brevides based soft rot resistance in potato breeding. (177)Lu-EDTMP, with only low bone marrow toxicity, provided significant pain relief to patients and considerably increased their mobility, resulting in an overall improvement in the quality of life. We recently tested the behavior of this type of catalyst in ethylene homopolymerization.

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Blood flow is modeled using a one-dimensional flow approximation, in which the cross-sectional area of elastic vessels is determined as a non-linear function of the transmural (blood minus external) pressure. Our results further indicate that Uncx4.1 may be involved in the differential cell adhesion properties of the somite. A method for microscopical observation and quantification of corneal neovascularization in the living mouse is described. Evidence-based medicine for rare diseases: implications for data interpretation and clinical trial design. Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review. The neonatal withdrawal inventory: a simplified score of newborn withdrawal. The results provide insight into a participatory design to guide design decisions for the type of intervention for which success relies largely on self-motivation. Based on the results from our functional assays, we conclude that the MSH2-M813V variant is not disease causing. Neuroanatomical correlates of naturalistic long-term outcome of obsessive-compulsive disorder treated with selective serotonin reuptake inhibitors. At age 39 (May 20, 1989), recurrent aygestin dose to stop bleeding aphasic state was unexpectedly observed during medical examinations.

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Clinical and neuropathological aspects of long-term damage to the central nervous system after lithium medication. Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. Infection of guinea pigs with the virus resulted in the development of allergic encephalomyelitis. Evaluation of BRM (biological response modifier) action of clarithromycin (CAM)--effect on cytokine expression in a mouse lung cancer model. Conventional follow-up of type 1 diabetic patients treated with continuous subcutaneous insulin infusion (CSII) was compared with intensive coaching using the Web and the cellular phone network for retrospective data transmission and short message service (SMS). Calcium antagonists and converting enzyme inhibitors are now widely used as first line therapy for high blood pressure. Polypeptide masses generated were matched to known standards using a search of the NCBI and/or GenPept databases for protein matches. In a recognition task (Study 2), memory performance and the frontal and parietal ERP old/new effects, reflecting familiarity and recollection, respectively, were not enhanced for beloved-related compared with friend-related words/phrases. Translation of the A36R mRNA in vitro produced a protein of the same size whether or not the translation reaction was performed in the presence of canine pancreatic microsomes. Results show that the more apertures a pollen grain has, the more quickly it germinates but that few-apertured pollen grains have faster growing pollen tubes and longer life expectancies.

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Insulin resistance is associated with increased risk of major cardiovascular events in patients with preexisting coronary artery disease. Our findings revealed a novel high-penetrance mutation in C1R as the cause of monogenic SLE. In addition IRS-1, IRS-2 and IGFBP-3 gene polymorphisms were determined by using polymerase chain reaction and restriction fragment length polymorphism. NK dendritic cells (NKDC) are recently described immunologic cells that possess both lytic and Ag-presenting function and produce amaryl and buy prolific quantities of IFN-gamma. For a combined chemo- and baroreceptor stimulation, the carotid sinus was perfused at a constant pressure of 100 mm Hg with venous blood bubbled with CO2.Twenty seconds after the onset of the perfusion the carotid sinus pressure was raised up to 200 mm Hg.

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Meeting the need for dental auxiliaries: personnel and programs. Neural cell alignment by patterning gradients of the extracellular matrix protein laminin. Statistical evaluation of 2021 radioiodine accumulation tests in the iodine deficient area of south Bavaria. Plasma micronutrients are associated with dietary intake and environmental tobacco smoke exposure in a paediatric population. Interlaboratory comparison of the CB6F1-Tg rasH2 rapid carcinogenicity testing model.

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