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Bitrim (Trimethoprim)

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Bitrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Altavit, Bacin, Bacta, Bacticel, Bitrim, Cotrimol, Cotrimox, Cotrimoxazol, Cozole, Erphatrim, Gentrim, Kaftrim, Licoprima, Medibiot, Megatrim, Metoxiprim, Noxaprim, Nufaprim, Onetrim, Ottoprim, Politrim, Primazol, Septrin, Spectrem, Sulbron, Sulfamethoxazol, Sulfamethoxazole, Suprasulf, Supreme, Tagremin, Trelibec, Trifen, Triforam, Trimethox, Trimetoger, Trisolvat, Trisul, Trisulf, Trisulfose, Tritenk, Wiatrim

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Artane, Zofran, Thorazine, Prilosec, Antivert, Viramune, Naprosyn, Aricept

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Also known as: Trimethoprim


Bitrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Bitrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Bitrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Dosage is based on your medical condition and response to treatment. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping it too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Tell your doctor if your condition persists or worsens.


If you overdose Generic Bitrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Bitrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Bitrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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A heat-stable fraction of low molecular weight from semi-anaerobic cells reactivates delta-aminolaevulate synthetase in extracts of oxygenated cells and appears to contain a compound responsible for the spontaneous activation. The composition of human hepatic bile during the postoperative period. Cats with cutaneous HSA treated with aggressive surgical excision of their tumors may have a good long-term prognosis. Multiple regression analysis using random effects for rheumatologists and adjustments for patient characteristics and treatments received, based on data derived from a panel study of persons with RA. Preventive, early, and aggressive therapeutic interventions are required to minimize this serious complication of transplant-associated immunosuppression. We measured BP in 111 hypertensive and 80 normotensive patients in both arms at the same time using identical Omron HEM 725 CIC automatic sphygmomanometers. PNU-63693 was effective in EAE at concentrations of 200 mg/kg, 100 mg/kg, 50 mg/kg, and as low as 25 mg/kg. The spatial distribution of neural crest-derived pigment cells in turtles differs markedly from those found in chickens and mice.

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While it is generally accepted that hypothalamic progesterone receptors function as estradiol-induced transcription factors in the induction of sexual receptivity in rats, hamsters, and guinea pigs, relatively little is known about their role in the mouse, a species which exhibits genotypic and strain differences in the responsiveness to steroid hormones. Taken together these data suggest that p48 may function as an anti-stress cell survival factor. Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation. We generated apolipoprotein E (apoE)-deficient (apoE-/-) MMP-9-deficient (MMP-9-/-) mice to determine the mechanisms and the main cell source of MMP-9 responsible for the plaque composition during accelerated atherosclerotic plaque formation. We carried out a retrospective study of patients presenting at our centre with histopathological diagnosis of primary GIT lymphoma between 1990 and 1994.

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Hemofiltration and peritoneal dialysis in infection-associated acute renal failure. Placental abnormalities in victims of the sudden infant death syndrome. Observation of shoemaker-levy impacts by the galileo photopolarimeter radiometer. The Ender method has advantages over existing operative methods, in that in our series the infection rate was zero and we found that the operation produced less shock. Contributory factors to the results of gravity-assisted pivot-shift test for anterior cruciate ligament injury: the significance of muscle torque around the knee. Quantitative reverse transcription-polymerase chain reaction of circulating miR-125b transcripts was performed directly in serum to improve the efficiency of miRNA assessment. Analysis of a sequenced cDNA library from multiple sclerosis lesions. The dimer of cyanamide, dicyandiamide, is formed upon ultraviolet irradiation of dilute cyanide solutions, and by the electron irradiation of a mixture of methane, ammonia, and water. Effects of pregnancy, lactation and dietary calcium on alveolar bone loss.

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Thirty-four healthy, nonsmoking male volunteers aged 18-45 years. Fourth, high expression of PP2C suppresses Atf1-dependent transcription of a stress-response gene. There appears to be plasticity associated with the addiction phenomenon in general as well as changes produced by addiction to a specific class of addicting drugs. However, the relationship between depressive mood and sexual dysfunction is bidirectional and further complicated by the sexual side effects of antidepressants which most often affect sexual arousal and orgasmic function. The possible interaction of the neutrophil-activating protein fenofibrate nanocrystallized 145 mg of Helicobacter pylori with target cell glycoconjugates was investigated by the binding of 125I-labeled recombinant protein to glycosphingolipids from human neutrophils in solid phase assays. A controlled trial of an expert system and self-help manual intervention based on the stages of change versus standard self-help materials in smoking cessation. These results suggest that disrupting focal pathological activity in limbic-cortical circuits using electrical stimulation of the subgenual cingulate white matter can effectively reverse symptoms in otherwise treatment-resistant depression. Pitfalls which can mask diagnosis using only a single test are renal failure, blood transfusion, diet or drugs. In HNSCC, disabling of p53 occurs in a high proportion of cases by mutation in the p53 gene, but other mechanisms of inactivation, such as the presence of human papillomavirus (HPV) and molecular abnormalities in other components of the pathway, are also recognised. Naphthalene nitration can lead to two possible isomers, 1- and 2-nitronaphthalene.

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Anaphylactoid purpura complicated by an irreducible intussusception. DNA synthesis and neuronal loss are induced in postmitotic Purkinje cells dependent upon the pRb-binding portion of SV40 large T antigen (T-ag). Helium-neon laser rays in addition to routine antibiotics appear to stabilize peroxide oxidation and normalize antioxidation enzyme activity more than antibiotics alone. LIG4(-/-), DNA-PKcs(-/-), and Ku70(-/-) MEFs show more pronounced repair defects in G1 than in G2. In vitro study confirmed the sustainable release of icaritin from PLGA/TCP/icaritin with the bioactive scaffold promoting the proliferation and osteoblastic differentiation of rat BMSCs. The hepatitis C virus nonstructural 5A (NS5A) protein is a pleiotropic phosphoprotein that has been shown to associate with a wide variety of cellular signaling proteins. Comparative studies of conceptus-endometrial interactions in Large White x Landrace and Meishan gilts. Hence, most patients with Rhodotorula fungemia reported in the literature survived with or without administration of antifungal agents.

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This was found to be due to Philadelphia chromosome positive CML. Effect of dietary versus pharmacological correction of hypertriglyceridemia on red blood cell membrane sodium/lithium countertransport activity. To define the effect of EHEC infection on epithelial gamma interferon (IFN-gamma)-Stat1 signaling, human T84 and HEp-2 epithelial cells were infected with EHEC O157:H7 and then stimulated with recombinant human IFN-gamma. Reduced plantar forces and VM EMG amplitude at 2 weeks post-surgery suggest a need for greater focus on restoring VM function before attempting closed kinetic chain exercises that require the full shock absorption capabilities of the quadriceps femoris muscle group. The construction of a questionnaire for the prediction of subsequent suicidal attempts: a preliminary study. Bactericidal properties of copper (II) complexes with 1-alkylimidazole. There was a decrease in Rb phosphorylation but without the induction of WAF1 protein.

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There was low morbidity and only one hospitalization due to an infectious episode. Thus the implanted embryos had a trophic effect on growth factor production by the endometrium, and the levels of expression were determined by viability and structural integrity of the conceptus. Infrared thermographic imaging (ITI) is the most sensitive objective imaging currently available for the detection of back disease in horses. Those ratings were combined with demographic and diagnostic data available in discharge abstracts and were then entered into multivariate regression analyses to model LOS. The VSP-A is a generic health related quality of life measure for adolescents aged 11-17 developed in France.

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Trans-18:2 consumption is associated with specific, less favorable indices of HRV in both older and young adults. Effect of chitosan intake on fecal excretion of dioxins and polychlorinated biphenyls in healthy men. The results of this study amaryl tablets suggest that duodenal drainage (Meltzer-Lyon test) is a valuable adjunctive diagnostic study in patients with gallbladder disease symptoms in whom normal or equivocal oral cholecystograms are obtained. The syntheses and antimitotic activity of several novel analogs of 2-methoxyestradiol are described. Segmenting multi-component microanalytical images consists in trying to find zones of the specimen with approximate homogeneous composition, representing different chemical phases. Latex agglutination test (LAT) for antigen detection in the cystic fluid for the diagnosis of cystic echinococcosis. Therefore, it may serve as an optimal choice for the first aid of large wounds with an arterial injury. Morphologic Variation and Mode of Growth of Devonian Trepostomatous Bryozoa. Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development.

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In all but the best-case scenario, casualty estimates exceeded the capacity of the only Department of Defense burn center. Low molecular weight N-maleated chitosan-graft-PAMAM (polyamidoamine) copolymer was prepared through N-maleated chitosan (NMC) by Michael type addition reaction to enhance its solubility in water as well as its cationic character for enhancement of DNA complexation. Salivary testosterone during the menstrual cycle in women with systemic lupus erythematosus. Placing of the lesions almost totally abolished the reflex responses to distension of the pulmonary vein-left atrial junctions and to low intensity stimulation of the aortic nerv. Both EG and GMG cells reacted positively to concanavalin A, wheat germ agglutinin, and phytohemagglutinin on lectin histochemical investigation, although common results were not always obtained for immunohistochemistry.

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Immunocytochemical methods for investigating receptor localization. The study has shown that Selol overcame the cell resistance, as doxorubicin-resistant cells were more sensitive towards Selol than sensitive cells. Right internal jugular vein approach as an alternative in balloon pulmonary valvuloplasty. Recent innovations enable a quantitative understanding of protein-free drug kinetics into semen and drug distribution into individual male genital tract glands. The indications and irradiation procedure are presented in the light of a case report of a patient with generalized intra-abdominal lymphosarcoma and no evidence of disease 5 years after treatment. Therapist and technique variables in behavior therapy of neuroses. Oxygen binding and aggregation of hemoglobin from the common European frog, Rana temporaria. The approach revealed pituitary adenylate cyclase activating polypeptide to be an indirect activator of adenylate cyclase in the ovine pars tuberalis. In fact, a reduction in Pax6 gene dose exacerbates the RPE-to-retina transdifferentiation seen in embryos homozygous for an Mitf null allele, and it induces such a transdifferentiation in embryos that are either heterozygous for the Mitf null allele or homozygous for an RPE-specific hypomorphic Mitf allele generated by targeted mutation. Percutaneous implantation of endoprostheses in the carotid arteries.

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