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Bitensil

Bitensil is an ACE inhibitor that is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack. Bitensil is also used to treat a disorder of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). This disorder can decrease the heart's ability to pump blood to the body.

Other names for this medication:
Amprace, Auspril, Bajaten, Baypril, Ciplatec, Convertin, Denapril, Ednyt, Enacard, Enacodan, Enalafel, Enalaprilmaleat, Enaldun, Enalek, Enalich, Enaprotec, Enecal, Enpril, Fabotensil, Gadopril, Hipertan, Hipertin, Iecatec, Ileveran, Korandil, Lapril, Laprilen, Lariludon, Lenimec, Lowtril, Mepril, Nalabest, Neotensin, Olivin, Pralenal, Priltenk, Pulsol, Renacardon, Renipril, Renistad, Renivace, Silverit, Tenaten, Ulticadex, Vasopren, Zacool

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Also known as: Enalapril

Description

Enalaprilat injection is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Enalaprilat works by blocking an enzyme in the body that is necessary to produce a substance that causes blood vessels to tighten. As a result, the blood vessels relax. This lowers blood pressure and increases the supply of blood and oxygen to the heart .

This medicine is available only with your doctor's prescription .

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 5 mg orally once a day Maintenance dose: 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses Comments: -Treatment is usually combined with diuretics and digitalis. -Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses Comments: -After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. -If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients. Comment: -Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Detailed Bitensil dosage information

Overdose

If you overdose Bitensil and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Bitensil overdosage: fainting, dizziness.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bitensil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Bitensil if you are allergic to enalapril:

you have hereditary angioedema; you recently took a heart medicine called sacubitril; or you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril).

Do not take Bitensil within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use enalapril together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking enalapril with aliskiren if you have kidney disease.

To make sure this medicine is safe for you, tell your doctor if you have:

kidney disease (or if you are on dialysis); liver disease; or an electrolyte imbalance (such as high levels of potassium in your blood).

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Enalapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breast-feed while you are using Bitensil.

Enalapril is not approved for use by anyone younger than 1 month old.

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We reviewed the contact investigation records for tuberculosis patients identified by the Tuberculosis Prevention and Control Center of Lleida, Spain, over a period of 7 years. None of the inhibitions on CaCl2 (6 mM) are reverted by Bay K 8644. Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate hosts. The Westwood-Squibb Center for Dermatology Research was created to foster the care of patients through research and education that supports the delivery of optimal dermatologic health care. All endoproteolytic activity directed toward proline residues in several rat tissues is shown to share one or more common antigenic determinants with rat brain proline endopeptidase. Methanol elicits the biosynthesis of 4-coumaroylserotonin and feruloylserotonin in rice seedlings. The venom was partially purified by gel filtration chromatography. Both dogs and humans are typically infected by ingesting infective stages, (i.e.

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The present study deals with the triglyceride fatty acid content and pattern of the soleus muscle in control animals and omega3-depleted rats. In terms of postjunctional alpha(2)-adrenoceptors in the pulmonary circulation, no evidence is available with regard to the receptor subtypes mediating vasoconstriction. Role of prokinetic drugs for treatment of postoperative ileus in the horse. In our opinion the overall outcome of patients with metastatic VIPoma may be improved best by maintaining the patients on medical therapy until treatment failure occurs. We also studied the tissue distribution of gene expression by Northern hybridization. It usually develops before the second year of life and is rarely seen in adults. The main purpose of the present study was to determine predictive factors related to 1-year mortality after primary cemented calcar-replacement bipolar hemiarthroplasty performed for unstable intertrochanteric fracture. Localization of 125-I-labelled antigen in germinal centres of mouse spleen: effects of competitive injection of specific or non-cross-reacting antigen. Here a molecular genetic approach was used to study the detailed genomic structure of 240 kilobases (kb) surrounding the H-2K gene and 150 kb of a partly homologous region located in the distal inversion of the t complex.

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Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53. A sodium leak current regulates pacemaker activity of adult central pattern generator neurons in Lymnaea stagnalis. The dorsal midbrain including the periaqueductal gray (PAG) is involved in the control of threat-induced vocalizations and other behavioral and autonomic defensive responses in adult animals. They represent examples of a striking and devastating but fortunately uncommon entity. HCC recurred at 5 months and 13 months posttransplant respectively, and chemotherapy and radiation therapy were performed. The steady-state current-voltage (I-V) relations of glutamate- and kainate-induced currents through homomeric channels fell into two classes: channels composed of either the GluR-A, -C, and -D subunits showed doubly rectifying I-V curves, and channels composed of the GluR-B subunits displayed simple outward rectification. The ACC/AHA guidelines were successfully applied to all 133 files by the two investigators. If the MDM2 feed-back inhibition of p53 is interrupted, a significant increase in functional p53 levels will increase p53-mediated therapeutic effectiveness. Recent findings suggest a role for heart failure in the etiology of osteoporotic fractures, yet the temporal sequence of occurrence of the 2 conditions needs clarification. Solid-state 13C NMR and quantum chemical investigation of metal diene complexes.

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Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats. Important work from the laboratory of Bart Hoebel has provided key information on neurochemical systems that interact with dopamine (DA) as potentially important components in both the development of addiction and the expression of compulsive behaviors such as binge eating. Asterixis seems to be due to a central effect of the drug unrelated to hepatotoxicity or sedation. A special problem is the evaluation of dose-finding trials with and without the assumption that the effects increase with increasing doses. In vivo studies have shown that changes in the characteristics of skeletal muscle fiber are determined by type of exercise or training. Effects of halogenated derivatives of ethanol on the nicotine acetylcholine receptor.

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Mouse mammary tissue can give rise to several characteristic types of premalignant hyperplasia and tumor, originating in a duct or acinus, that progress to carcinoma. Monocyte and neutrophil analysis included quantitation of receptors for C5a, formyl-met-leu-phe, and C3bi (CR3). In the current study, we examined the efficacy of combined treatment with OCT and PAS in PCK rats, an autosomal recessive PKD model. Paediatric innovation in Pakistan: our experience and a call to action. adult population (18 years of age or older) conducted in 47 U.S. To define the role of polycystin-1 in formation of intercellular contacts and cell polarity during epithelial morphogenesis, we have utilized a 3D MDCK in vitro model of tubulogenesis and cystogenesis. Quantitative ADC maps were calculated with images with b values of 0, 150, and 500 s/mm2 (ADC0-500) and with images with b values of 150 and 500 s/mm2 (ADC150-500). At 20 min post-ingestion, the red wine group showed higher power in the alpha band, lower RP of low frequencies and decreased correlation, as compared to the placebo group.

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Turnover of standard-gammaglobulin, pH-4-gammaglobulin and pepsin desaggregated gammaglobulin and clinical implications. To identify the difference in the number of hours of TV watching, number of TV sets, and the number of advertisements they recalled, a one-way ANOVA was used. Ab initio electronic structure calculation of a new gene system using the negative factor counting method. Using polyclonal antisera raised against the International Reference Preparations, we found that the deglycosylated hormone could be bound by the anti-beta antiserum although at a much lower dilution than the native antigen, suggesting the presence of at least one glycosylation-independent epitope in the beta-subunit. Epithelial lining the oral cavity, i.e., superficial, are essentially stratified squamous epithelia, with the exception of taste buds. IL-10 can directly regulate hepcidin in primary macrophages but not in HepG2 cells. Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Hypertrophic cardiomyopathy and left ventricular hypertrophy in hypertensive heart disease with mildly reduced or preserved ejection fraction: insight from altered mechanics and native T1 mapping. DNA from the does 5 mg of zyrtec work no-Ig-producing cells contained fragments coding for the rearranged lambda 1 chain gene and the germ-line V lambda 2 region, but it lacked the sequences coding for the rearranged lambda 2 chain gene and the germ-line V lambda 1 and J-C lambda 1 regions.

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