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Birodogyl (Metronidazole)

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Birodogyl is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

Other names for this medication:
Aldezol, Amebidal, Aminidazole, Biozyl, Buccoval, Flanizol, Florazole, Geloderm, Gynoplix, Litagyl, Mebadiol, Mecozol, Menizol, Metroderme, Metrogel, Metrolotion, Metrovax, Metrozole, Minegyl, Nidagel, Orvagil, Patryl, Polibiotic, Protogyl, Protozol, Rovamet, Tolbin, Trichazole, Trichomonacid, Tricodazol, Triconex, Vagilen

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Also known as: Metronidazole


Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Birodogyl ER. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and loss of balance or coordination.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Birodogyl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


As a rule, the usual duration of therapy with i.v Metronidazole or other imidazole derivatives is usually less than 10 days. This period may only be exceeded in individual cases after a very strict benefit-risk assessment. Only in the rarest possible case should the treatment be repeated. Limiting the duration of treatment is necessary because damage to human germ cells cannot be excluded.

Intensive or prolonged Metronidazole therapy should be conducted only under conditions of close surveillance for clinical and biological effects and under specialist direction. If prolonged therapy is required, the physician should bear in mind the possibility of peripheral neuropathy or leucopenia. Both effects are usually reversible.

In case of prolonged treatment, occurrence of undesirable effects such as paraesthesia, ataxia, dizziness and convulsive crises should be checked. High dose regimes have been associated with transient epileptiform seizures.

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Protein stability and ligand binding: new paradigms from in-silico experiments. HAP-Glass-alpha-Al2O3 gradient coating on alumina ceramics substrate was prepared by multi-layer slurry-dipping and sintering process, effects of the composition of the coating on the microstructure and adhesion strength of the gradient coating were studied. It is not clear whether this is consequent on the experience of chronic physical ill health. CNF1Cter was sufficient to induce a typical CNF1 phenotype when microinjected into African green monkey kidney cells (Vero cells), and was able to modify Rho as previously reported for CNF1. Given the emerging concept of thrombin and its specific receptor, protease-activated receptor 1 (PAR1), as important players in inflammation and cell proliferation, we investigated whether thrombin and PAR1 might be involved in the pathophysiology of the disease, using a primary cell culture system of endometriotic tissues. Effect of protracted ultrasonic irradiation on the growth of seedlings of Vicia faba. Diagnostic classification of shoulder disorders: interobserver agreement and determinants of disagreement. Dimensions of care in five United States nursing homes: identifying invisible work in care-giving.

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Prevention of venous thrombosis and pulmonary embolism by electrical stimulation of leg muscles. It summarizes the use of microextraction methods in food flavor compounds analysis based on papers published in the last 5years, and discusses the potential of microextraction methods in this field. Binding was not affected by the presence or absence of zinc or EDTA. The subcellular distribution of acetylcholine, choline acetyltransferase and cholinesterases in lobster walking leg nerves. The other two mutants (narL and Rv3220c) showed no change compared to the wild-type H37Rv strain. Recent research combining molecular genetics, endocrinology, and neuroimaging demonstrated that variations in dopamine-related genes and in hormone levels affect the physiological properties of the dopaminergic system in nonhuman primates and modulate the processing of reward and social information in humans.

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In certain areas-substance abuse, dietary practices, and birth outcomes-there is evidence that acculturation has a negative effect and that it is associated with worse health outcomes, behaviors, or perceptions. Further examination of the central nervous system (CNS) revealed low or undetectable levels of claudin-3 and claudin-4 in all regions tested by Western and immunohistochemical analysis. Using this method we deduce a general condition for determining the Talbot distance. Parameters contributing to efficient ion generation in aerosol MALDI mass spectrometry. The antitumor sensitivity test in vitro was devised with MTT assay. The possible roles of organic and psycho-social factors in the psychopathology of this peculiar delusion in this patient are discussed. Immature DC are considered to be specialized in antigen capture and processing, whereas mature DC present antigen and have an increased T-cell stimulatory capacity. The transmission of UVR through fabric depends on the wavelength and varies with factors such as type of fiber, fabric mass, cover, and color. Insights into the determinants of beta-sheet stability: 1H and 13C NMR conformational investigation of three-stranded antiparallel beta-sheet-forming peptides.

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Additionally, a non-target analysis was performed in both types of samples with the objective of investigating the presence of other non-selected organic compounds taking advantage of the potential of GC-TOF MS (high sensitivity in full-spectrum acquisition mode, accurate mass measurements) for searching unknowns. Three different trials to examine the cause of upper stem rot (USR) infection in oil palm failed to achieve any infection. Chorion patterns on eggs of Lutzomyia sandflies from the Peruvian Andes. In this work, erythropoietic activity and interferon production have been studied in LCM virus-infected nude mice. Direct cell/cell communication in the lymphoid germinal center: connexin43 gap junctions functionally couple follicular dendritic cells to each other and to B lymphocytes.

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Analytical methods used to measure acrylamide concentrations in foods. Sixteen dogs were used as experimental animals and were subdivided into two groups of eight. Technic for the sectorial evaluation of facility of aqueous humor outflow. During the 9-year period 1964 to 1972 inclusive, a total of 2130 women with breast cancer were seen, with break-down by religion as follows: Hindus (1259), Muslims (306), Christians (264), Parsi (Zoroastrians) (226), Jains (25), Buddhists (26) and others (24). Forty tumors with cytogenetically defined 7q deletions, twenty-nine tumors without cytogenetically visible 7q deletions, and five tumors with no cytogenetic information were examined for allelic loss of D7S518, D7S666, D7S515, D7S658, D7S496, D7S692, and D7S471. Pars plana vitrectomy with removal of the internal limiting membrane in the treatment of persistent diabetic macular edema.

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In this study, we have used (insert statistical method here) to compile unique DNA methylation signatures from normal human heart, lung, and kidney using the Illumina Infinium 27 K methylation arrays and compared those to gene expression by RNA sequencing. who showed that very large charge reductions are achieved with very high GB(B) proton sponges. TDE identifies impaired diastolic function in patients with RA that may not be detected by conventional measurements. Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization. This trade-off renders the cells specialized in this low-carbon flux state to compete for the available glucose and get rid of over-overcapacity. Outcomes following V-Y advancement flap reconstruction of large upper lip defects. Workforce study in emergency medicine: a perspective from academic emergency medicine. Rate of information processing in visual perception: some results and methodological considerations.

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Conversely, when these associated signs go undetected or misdiagnosed, therapeutic intervention may be delayed unnecessarily. CD23 is the low-affinity receptor for IgE on B cells and is thought to play an important role in regulation of IgE production. Pre-RT computed tomography (CT) scans were used to calculate the three-dimensional (3D) dose distribution, reflecting tissue density inhomogeneity corrections. Such integrated systems will greatly facilitate the constructive cycle of computational model building and experimental verification that lies at the heart of systems biology. Cooling rates measured in the metal phases are uniform and consistently lower than those of most iron meteorites. Ribonucleic acid synthesis in vitro in primary spermatocytes isolated from rat testis. Immediate reaction to methylprednisolone with tolerance of other corticosteroids. This method yields excellent pain relief that does not deteriorate for at least 15 years. This system provides a simple model for studying the initial mechanisms of chondrocytes dedifferentiation. Mitochondria isolated from the liver of EFA-deficient rats exhibited a high tendency to swell and a high phospholipase A(2) activity in comparison with those prepared from normal rat liver.

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Epigenetic silencing of the MGMT (O6-methylguanine-DNA methyltransferase) DNA-repair gene by promoter methylation compromises DNA repair and has been associated with longer survival in patients with glioblastoma who receive alkylating agents. A steady increase of expression starting from the initial stages of the interaction was found for interleukin-1beta. With special emphasis to Gleason pattern specific tumor volumes (TVs) the relationships between PCA3 score and different characteristics of tumor aggressiveness were meticulously analyzed. Comparison of sparfloxacin and clarithromycin in the treatment of acute bacterial maxillary sinusitis. Multivariate analysis by means of Quantification theory II revealed that sLe(x) expression was an independent risk factor for liver metastasis from gastric cancer. Poor responders to ovulation induction: is proceeding to in-vitro fertilization worthwhile?. The influence that individual items have on the development of pressure ulcers and the impact of this influence on score outcomes has not yet been established. Two series of oleanolic acid derivatives were synthesized and their inhibitory activity on the formation of osteoclast-like multinucleated cells (OCLs) induced by 1alpha,25-dihydroxy vitamin D3 was evaluated in a co-culture assay system.

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Moreover, very recent research has revealed that biotic constraints can also be important: many plant species are not present in the soil seed bank and their dispersal is limited in the present fragmented landscape. Important additional influences of sleep on blood pressure may be exerted through respiratory variations, so that sleep-disordered breathing is bound to alter nocturnal blood pressure. The results from both of the studies were consistent with object-based models of attentional selection. Network effects of subthalamic deep brain stimulation drive a unique mixture of responses in basal ganglia output. There is a dramatic increase in fractures around the time of diagnosis of myeloma, most of which are pathologic fractures. A cross-sectional study was conducted upon the construction of a sampling frame of sex work-related bars in the municipalities of the Soconusco region. Campylobacter jejuni translocation across intestinal epithelial cells is facilitated by ganglioside-like lipooligosaccharide structures. This paper employs structural equation modeling to infer the latent processes responsible for correlated growth in the pain report, evoked potential amplitudes, pupil dilation, and skin conductance of 92 normal volunteers who experienced 144 trials of three levels of increasingly painful electrical stimulation.

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We present a novel technique combining both flaps for closure of moderate-sized nasoseptal perforations. Mechanical ventilation is an age-dependent, costly, and relatively nondiscretionary medical service that may be particularly affected by the aging population. Given their uncertain clinical implications, we must either redefine them or eliminate them from practice. Comparison of the performance of pigtail catheters with different number of sideholes. Effect of paroxetine hydrochloride (Paxil) on fatigue and depression in breast cancer patients receiving chemotherapy. Interestingly, for slow second-order stimuli we observed that the eye could move faster than the target, leading to small, corrective saccades in the opposite direction to the ongoing smooth-pursuit eye movement. A significant increase in the clearance (CL/F) rate of carbamazepine was observed only after multiple dose honey treatment. Laser tissue soldering resulted in similar patency when compared to a conventional 2 layered sutured anastomosis while decreasing operative time. From our results, it appears that there is a good correlation between storage at 37 degrees and the tests usually required by the manufacturer, i. The aCRT algorithm is safe and at least as effective as BiV pacing with comprehensive echocardiographic optimization.

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Tissue injury from release of reactive oxygen species by AMs may be important in the pathophysiology of the meconium aspiration syndrome. Spontaneous urinary extravasation in non-acute ureteric obstruction: a report of four cases. Restenosis after percutaneous transluminal coronary angioplasty (PTCA) occurs due to vascular smooth muscle cell proliferation and migration. The steroidogenic acute regulatory protein as a target of endocrine disruption in male reproduction. However, the promise of bionanotechnology has not materialized beyond the biomedical field due in large part to issues of scalability, purity, and cost of manufacturing. We also aimed to determine whether HREC migration and proliferation correlate with the levels of protein kinase B (Akt) and extracellular-signal-regulated kinase (ERK) phosphorylation and activation. Survey of international interests within the American Society of Allied Health Professions. Here we show that inhibitory/regulatory C/EBP family proteins, Ig/EBP (C/EBPgamma) and CHOP (C/EBPzeta), but not positively functioning NF-IL6 (C/EBPbeta), are constitutively multiubiquitinated and subsequently degraded by the proteasome. Central cell nuclear-cytoplasmic incongruity:a mechanism for segregation distortion in advanced backcross and selfed generations of (Allium cepa L.

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In this study we demonstrate that morphological specializations of the pectoral fin rays of the benthic longhorn sculpin (Myoxocephalus octodecimspinosus) have specific functional consequences both within and among individual rays. Introduction of the 5-HT3B subunit alters the functional properties of 5-HT3 receptors native to neuroblastoma cells. In two patients treated with NDCs there were minor complications, i.e. This may be the reason that the biological behavior of D-GCTS was more aggressive, destructive and recurrent. Somatic cell lesions induced by the base analog 5-bromodeoxyuridine. A stereoselective and atom-efficient approach to multifunctionalized five- and six-membered rings via a novel michael-initiated intramolecular Diels-Alder furan reaction. Heminasal proboscis with associated microphthalmos and encephalocele. There was no differentiation between invasive and noninvasive carcinoma.

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It is concerning that the percentage of TBM cases out of the total study population has more than doubled compared with that in previous surveys. She resumed normal activity within 5 days and remains well one year later. Serum leptin concentrations are determined by total body fat mass, but the influence of visceral fat accumulation and other metabolic factors have been clinically determined. The distribution of radioactive polonium-210, a decay product of radon-222, shows enhanced concentrations at the edges of lunar maria. Specimens of putative basal angiosperms and primitive mammals are clarifying details of the early radiations of these major clades. Corneal higher-order aberrations significantly increased, even in clinically successful orthokeratology cases. There is a progressive induction of mobility at increasing hydration from the periphery toward the protein interior. Primary hyperparathyroidism (PHP) is an infrequently diagnosed disorder in cats. Seventeen compounds were isolated from southern African Hyacinthaceae species, one from the Madagascan gentian Tachiadenus longiflorus Griseb. The pedunculated tumor was resected during left thoracotomy (posterolateral incision).

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Our results may have practical applications in the rehabilitation of peripheral nerve-injured patients. The evolution of the weather system during the ozone episodes (24 July and 24 August) indicates that hot and dry air and a stable weak pressure field intensified the production of ozone and allowed it to accumulate. Its effectiveness depends on the administration schedule, and chronic addition seems to be the most effective treatment. Study on the change of bFGF in reticular formation of medulla oblongata after primary brain-stem injury. We examined common factors in vehicular drowning deaths that might lead to changes in equipment or training. Regulators of VEGF expression, such as reactive oxygen species, may enhance neovascularization of atherosclerotic and restenotic arteries. A single-amino-acid substitution in the P2 domain of VP1 of murine norovirus is sufficient for escape from antibody neutralization. Development of polyploid F1 X TO embryos to the blastocyst stage did not differ significantly form that of untreated embryos. Protein cofactors represent a unique class protonix dosing ulcer of redox active posttranslational protein modifications formed in or by metalloproteins. PMK1 phosphorylation also was detected in the vegetative hyphae and appressoria of transformants expressing the MST7(S212D T216E) allele.

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Triflupromazine versus pentylenetetrazol-nicotinic acid for treatment of chronic brain disease on a general-hospital psychiatric service. has anyone taken xanax while breastfeeding The pandemic influenza A(H1)pdm09 (PI) was introduced to Germany in April 2009. The normalized indices of hemolysis (NIH) of the pumps with 0, 2, 3, and 4 secondary vanes and the pump with 2 secondary channels were 0.0797, 0.0866, 0.104, 0.157, and 0.0591, respectively. Higher MAAS scores were associated with lower mood disturbance and stress symptoms in cancer patients, and the structure of these relations was invariant across groups. However no progeny virus could be detected after HIV-1 infection. Generally, ectoparasite remains are rarely found among archeological material. Specific inhibition of Akt using the dominant-negative Akt plasmid also resulted in enhanced radiation-induced autophagy. There are scarce data on estimating the time of completing kidney maturation in very-low-birth-weight (VLBW) infants.

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Nuclear factor kappaB nuclear translocation upregulates c-Myc and p53 zanaflex 6 mg capsule expression during NMDA receptor-mediated apoptosis in rat striatum. The photochemical trapping rate from red spectral states in PSI-LHCI is determined by thermal activation of energy transfer to bulk chlorophylls. DNA binding activity of the mammalian translation elongation complex: recognition of chromium- and transplatin-damaged DNA. The magnitude of increased activity at the distractor site was correlated with the amount of curvature toward the distractor. In contrast, the removal of FapyA by hOGG1 was not as robust as FapyG or OG, and was only significant when the lesion was paired with C. The objective of this study was to evaluate the activity and safety of oral capecitabine in combination with docetaxel and epirubicin (TEX) as first-line treatment for patients with locally advanced/metastatic breast carcinoma. Fluoride adsorption data were described by both anion exchange and H-bonded complexation mechanisms. Twice daily RBC-based triple therapy with metronidazole and clarithromycin for 1 week is well tolerated and effective in eradicating H.

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Effect of radon baths of different concentrations on the cardiorespiratory system of patients with ischemic heart disease. Eight children who were receiving corticosteroids had been small for their age before starting steroid treatment. Clarification of its efficacy as an augmentation therapy and in patients with refractory depression and its role in improving the efficacy and reducing the extrapyramidal effects of antipsychotic drugs would also help to establish its clinical value. As yet, a causal link between the presence of environmental hazards and falls in older people has not been established. The average age of the patients at injury was 11.6 years (range 5-17 years), whereas their average age at follow-up was 35.5 years (range 22-56 years). The primary function of the coagulation cascade is to promote hemostasis and limit blood loss in response to tissue injury. Our examination showed that a number of specimens apparently free of cholesteatoma after macroscopic examination had microscopic can i take valium with blood pressure tablets evidence of cholesteatoma.

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To understand the action of FGF-1 in T cells, studies were initiated in Jurkat T cells that express the signaling isoform of FGF receptor-1. The estimated aetiological fraction for both associations was approximately 40 per cent, suggesting that although infected cattle may have a significant role in the transmission of TB their importance relative to the badger may have been over-estimated in the Northern Ireland TB scheme. Three families with maternal immunization against fetal PLT antigens were analyzed. Puerperal metrorrhagia caused by drugs administered during pregnancy and the puerperium. The apparent abundance of mRNAs in axons raises the possibility that local translation has many more functions than previously thought. Restored T-cell activation mechanisms in human tumour-infiltrating lymphocytes from melanomas and colorectal carcinomas after exposure to interleukin-2.

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