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Bipreterax (Aceclofenac)
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Bipreterax

Bipreterax is believed to act via primarily inhibition of angiotensin-converting enzyme (ACE) activity. It is used in patients with arterial hypertension, chronic heart failure, to prevent recurrent stroke in patients who have already had a stroke or transient ischemic attack, stable coronary heart disease for decreasing of complications in patients with stable coronary heart disease.

Other names for this medication:
Aceclofenac, Acertil, Acerycal, Agulan, Aldoc, Armix, Asyntilsan, Bionoliprel, Biprel, Bipreterax, Cardipen, Coveram, Coverene, Coverex, Covinace, Domanion, Dorover, Indapril, Inopil, Midopril, Noliprel, Pendoril, Pendrex, Percarnil, Perindal, Perindan, Perindo, Perindox, Prestance, Prestarium, Preterax, Prexanil, Prexum, Prindace, Procaptan, Provinace, Reaptan, Stopress, Teraxans, Vectoryl, Vidotin

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Also known as: Aceclofenac

Description

Bipreterax is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys. This causes blood vessels to relax, allowing blood to flow more freely and at a lower pressure, and increasing the heart's ability to pump blood in some types of heart failure. Bipreterax is also known as Coversyl, Perindopril, Acertil, Armix, Coverene, Coverex, Coversum, Prestarium, Prexanil, Prexum, Procaptan. Generic name of Bipreterax is Perindopril. Brand name of Bipreterax is Bipreterax.

Dosage

Usual Adult Dose for Coronary Artery Disease:

Initial dose: 4 mg orally once a day for 2 weeks, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Adult Dose for Hypertension:

Initial dose: 4 mg orally once a day Maintenance dose: 4 to 8 mg orally per day in 1 or 2 divided doses Maximum dose: 16 mg/day Comments: In patients treated with a diuretic, consider reducing the diuretic dose prior to starting this drug.

Usual Geriatric Dose for Coronary Artery Disease:

Greater than 70 Years: Initial dose: -Week 1: 2 mg orally once a day -Week 2: 4 mg orally once a day, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Geriatric Dose for Hypertension:

Initial dose: 4 mg orally per day in 1 or 2 divided doses Comments: Experience with doses above 8 mg is limited; administer with careful blood pressure monitoring and dose titration.

Detailed Bipreterax dosage information

Overdose

If you overdose Bipreterax and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bipreterax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Bipreterax if you are allergic to perindopril or if:

you have hereditary angioedema; you recently took a heart medicine called sacubitril; or you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, or trandolapril.

Do not take Bipreterax within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use Bipreterax together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Bipreterax with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

kidney disease (or if you are on dialysis); liver disease; heart disease or congestive heart failure; diabetes; or a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

Do not use if you are pregnant, and tell your doctor right away if you become pregnant. Perindopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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Allogenic transplantation of hemopoietic stem cells in low-intensity regimes in patients with hematological malignancies. The absence of published reports on contraindications and complications of cell therapy is worthy of note, because the analysis of unsuccessful application of MSC will help to determine the indication for this treatment, and hence, to improve the efficiency of cell technologies in the future. Host-protective fragments and antibody binding epitopes of the Taenia ovis 45W recombinant antigen. Hereditary tyrosinaemia type 1 (HT1) is caused by an enzymatic defect in tyrosine metabolism. Simvastatin in the secondary prevention of coronary heart disease.

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Behavior of ornithine-carbamoyl-transferase in acute liver diseases. Quantitative cholescintigraphy: selection of random dose for CCK-33 and reproducibility of abnormal results. In common diagnostic practice, such dynamic patterns are analysed by direct inspection of frame sequences through the use of a moviola. Chromosomal aberrations in workers professionally exposed to lead. Our results suggest that the addition of antibiotics to a regimen that includes steroids may have a beneficial effect on short-term outcomes for patients hospitalized with AE-COPD.

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As a result, no reliable astrophysical information has been derived from the OH observations, but a large body of information is waiting to be unraveled. In contrast, the spermatocytes of G1 x AT allotetraploids had the normal chromosomal behavior with only 100 bivalents found in meiosis I. Parental opinions about facial plastic surgery for individuals with down syndrome. New radiologic technique: advancement of multislice row of data CT for abdominal imaging. One of seven patients treated at 420 mg dose experienced DLT (grade 4 leucopenia, grade 4 mucositis and grade 4 diarrhoea), and this was considered the recommended dose for phase II studies. At 1 hour, there was adherence of the what is the work of celebrex 200 mg ESCs, EECs, and Myos on the perimeter of PMCs. At the end of the 17th century, he performed dissections on the corpses of executed criminals to teach and study anatomy. Development of effective resuscitation agents for blood-loss replacement in trauma or surgery is extremely important despite substantial improvements in screening methods of blood from human donors. Careful antepartum, intrapartum and postpartum management of women with high-risk chronic hypertension in pregnancies may reduce morbidity and mortality. Optical coherence tomography and fundus microperimetry imaging of spontaneous closure of traumatic macular hole: a case report.

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