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Biclar (Clarithromycin)
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Biclar

Biclar is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections, lyme disease, strep throat, skin infections, H. pylori infection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma, chlamydia and mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Abbotic, Aeroxina, Binoclar, Biotclarcin, Cidoclar, Clamycin, Clarimax, Clarimed, Clarimycin, Claripen, Claritab, Clarithromycin, Claritrox, Clariva, Clariwin, Claromac, Claron, Clathrocyn, Egelif, Eliben, Emimycin, Gervaken, Hecobac, Italclar, Kailasa, Kalecin, Karin, Klabax, Klabion, Klarifor, Klarigen, Klarimac, Klarimax, Klarithran, Kleromicin, Kofron, Larizin, Lekoklar, Likmoss, Lyoclar, Macrol, Macromicina, Monozeclar, Onexid, Preclar, Rocin, Rodizim, Rolicytin, Synclar

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Also known as: Clarithromycin

Description

Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection.

Clarithromycin belongs to the class of medicines, known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain clarithromycin. It may not be specific to Biclar. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You may take this medicine with meals or milk or on an empty stomach. However, clarithromycin extended release tablets should be taken with food.

If you are using the extended-release tablets:

Swallow the tablet whole. Do not break, crush, or chew it. While taking the extended-release form of this medicine, a part of the tablet may pass into your stools. This is normal and is nothing to worry about.

Measure the oral liquid with a marked measuring spoon, syringe, or cup. The average household teaspoon may not hold the right amount of liquid. Shake the bottle well before each use.

If you are taking clarithromycin and zidovudine, these medicines should be taken at least 2 hours apart.

Keep using this medicine for the full time of treatment, even if you or your child begin to feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release tablets): For bacterial infections: Adults—1000 milligrams (mg) once a day for 7 to 14 days. Children—Use and dose must be determined by your doctor. For community-acquired pneumonia: Adults—1000 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension and tablets): For bacterial infections: Adults—250 to 500 milligrams (mg) every 12 hours for 7 to 14 days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 12 hours for 10 days. Infants younger than 6 months of age—Use and dose must be determined by your doctor. For community-acquired pneumonia: Adults—250 milligrams (mg) every 12 hours for 7 to 14 days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. Infants younger than 6 months of age—Use and dose must be determined by your doctor. For prevention or treatment of Mycobacterium avium complex (MAC) infection: Adults—500 milligrams (mg) 2 times a day. Children 20 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight, up to 500 mg, 2 times a day. Children younger than 20 months of age—Use and dose must be determined by your doctor. For treatment of ulcers associated with H. pylori: Adults—500 milligrams (mg) every 8 hours for 14 days in combination with omeprazole, 500 mg every 12 hours in combination with amoxicillin and lansoprazole for 10 or 14 days, or 500 mg every 12 hours in combination with amoxicillin and omeprazole for 10 days. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Biclar and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Biclar overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the oral liquid. Throw away any unused mixed medicine after 14 days.

Detailed Biclar dosage information

Side effects

The most common side effects associated with Biclar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Doubling time for S but not F phase cells was proportional to CAP concentration, indicating that both kinds of mitochondria were present and functioning. During speech pathology professional preparation there is a need for adequate student instruction with speech-restructuring treatments for adults. Knowledge, behavior and beliefs related to cervical cancer and screening among Turkish women. We installed the Durham sampler on the roof (27.4 m on the ground) of Kagawa Medical University in 1989 to survey pollen dispersion in Kagawa prefecture and have investigated the pollen survey from 1989 to 2001. ASA was determined with an anti-human spermatozoa immunoglobulin G test. The production of mature germ cells capable of generating totipotent zygotes is a highly specialized and sexually dimorphic process. Moreover, some violations in the rules of the preparation of disinfecting solutions and the treatment of the hands of the personnel were established. It may be that DFPP can remove some circulating pathogenic factors other than AChR antibodies more efficiently than PA. The device-assisted training program resulted in hypertrophy of the iliocostal and longissimus muscles and an increase in muscle strength in patients with surgically stabilized vertebral fractures.

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Materials from 9 patients (serum, heparinized blood and urine) were investigated by serological methods (ELISA and Western blot), for the presence of specific antigens and virus capable of replication, and also by genetic methods (hybridization and PCR). Mutations N34S and P55S of the SPINK1 gene in patients with chronic pancreatitis or pancreatic cancer and in healthy subjects: a report from Finland. Proceedings of the 1998 Tri-Service Symposium on Occupational Medicine. In summary, C-CAM was strongly expressed in a specific spatiotemporal pattern in trophoblasts actively involved in formation of the placental tissue, suggesting an important role in placental development. Optimal dosing schedule in combination therapy with irinotecan and doxifluridine in a human colorectal cancer xenograft model. A distinct rise in staining intensity was first observed by P7 in layers I-III. By doing so they prevent GTP-dependent activation and simultaneously expose the target threonines on the switch I loop for phosphorylation by ROP18, resulting in permanent inactivation of the protein. Single amino acid substitution of serine82 to asparagine in first intracellular loop of human cholecystokinin (CCK)-B receptor confers full cyclic AMP responses to CCK and gastrin. The nucleotide sequence of the entire genome of Chuzan virus, which belongs to the Palyam serogroup orbiviruses and causes congenital abnormalities of cattle, has been completed by analysis of the genes encoding minor core proteins (VP1, VP4 and VP6) and non-structural proteins (NS1, NS2 and NS3). To assess the comparable efficacy and adverse effect profile of two extended-release preparations of nifedipine--gastrointestinal therapeutic system (GITS) and coat-core (CC)--in patients with mild-to-moderate hypertension.

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The transwell method was also used to discriminate fast migrating cells and slow migrating cells, in which expression of both MMP-9 and AQP4 was investigated by using immunofluorescence. A comparative study of the nutrition requirements of the genus Bacillus. To investigate surfactant in newborn babies we analysed 125 pharyngeal aspirates for the L/S ratio and bubble clicking. Thirty-four out of 68 infants developed the syndrome, the incidence being greatest among the least mature. To obtain 5 mm of pathologically clear margin an in-situ margin of resection of at least 8 to 10 mm needs to be taken. Mechanistically, loss of Bif-1 sequesters internalized EGF in Rab5-positive endosomes and delays EGFR trafficking to lysosomes. Determination of petroselinic acid by microreactor chromatography. Report of an Interprofessional Task Force University of Illinois College of Medicine Center for the Study of Medical Education December 1966. The patient, a 54-year-old woman, had undergone leftsided hip replacement five years before and several subsequent operations on the left hip due to dislocation and loose cup. When the subject was fully alert but not engaged in any specific task, PD2 was between 5.2 and 5.9.

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Advanced stage, lymph node involvement and tumour size correlated statistically significantly with poor loco-regional control. Hemodynamic rounds series II: hemodynamics of constrictive physiology: influence of respiratory dynamics on ventricular pressures. a highly resistant chitinous eggshell and the release of toxic substances. Specialty conference: management of infants with diaphragmatic hernia. The aim of the present study was to evaluate potential association and risk of VEGF-A and TGF-beta1 in human coronary atherosclerotic lesions. In the future, specific intervention directed at the promotion of physical activity in the population is necessary. Content of nucleic acids and histones in the human placenta and its cell nuclei at different periods of pregnancy. These strains grew at nearly the wild-type exponential rate, but only after an abnormally prolonged lag period of a duration that depended on the initial cell density.

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coli ASP, Erwinia ASP was substituted at the same dose and schedule. Because maturation occurs in the absence of transcription, posttranscriptional regulation of Aurkc mRNA, coupled with the greater stability of AURKC protein, provides a means to ensure sufficient Aurora kinase activity, despite loss of AURKB, to support both meiotic and early embryonic cell divisions. Simultaneous saccharification and fermentation of steam-pretreated bagasse using Saccharomyces cerevisiae TMB3400 and Pichia stipitis CBS6054. Quality group of medical practitioners: thoughts on the course of one of the groups in Fribourg. These results establish the presence of TAFI in platelets and suggest a role for platelet-derived TAFI in the protection of the clot against fibrinolysis. A panel of unique and potent agonist DR4 Atrimer complexes with subnanomolar affinity to DR4 and no detectable binding to DR5 or the decoy receptors was identified.

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Molecular cloning and expression of a thermostable xylose (glucose) isomerase gene, xylA, from Streptomyces chibaensis J-59. Furthermore, both the phosphatidylinositol 3-kinase (PI3K)/Akt and Ras/Erk pathways were activated in a sustained manner when PER or 5YF-expressing cells were stimulated with PDGF. As acid-base status has an effect on bone formation and remodelling, chronic metabolic alkalosis was induced in 3-week-old rats for 6 and 7 weeks with 0.25 mol/1 of NaHCO3 in their drinking water to determine whether it has any effect on dentinogenesis in the molars. Applying the GRADE system to the results of this review however, shows that the quality of evidence is low, because although all four studies are RCTs there were serious methodological limitations in the studies (unclear risk of selection bias and high risk of detection bias) and imprecision (small sample size). Gastrointestinal stromal tumours: an analysis based on personal experience. Using SPSS/AMOS (version 18), the study utilizes New York State data extracted from the 2007 BRFSS national dataset to test a well-known HRQoL model developed by Wilson and Cleary (J Am Med Assoc 59-65, 2). During the early phase of body development, skeletal stem cells and osteoblastic progenitor cells migrate to form initial rudiments for future skeletons. The pH activity profile of p-nitrophenyl penta N-acetyl-beta-D-chitopentaoside hydrolysis by mouse lysozyme M was similar to that of hen lysozyme, but the hydrolytic activity of mouse lysozyme M was lower. The novel sensor makes it possible to monitor the different types of wastewater rapidly without pretreatment, and it can be used for an active process control of sewage treatment works. There were wide variations in clinical presentation, clinico-pathologic patterns, and the stage of the HIV infection at vasculitis onset.

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Thus, this bacterial type of signaling system is essential for responses to a class of hormones in plants. A preliminary appraisal of the prognostic valve of ballistocardiography. Patients who suffer from mental fatigue after a stroke or traumatic brain injury (TBI) have a drastically reduced capacity for work and for participating in social activities. In conclusion, regimens with both nevirapine and efavirenz seem to result in similar antiviral and immunological efficacy with an increased incidence of adverse events compared with single NNRTI is flomax safe to take while breastfeeding regimens. These genomic modulations observed on large-scale cDNA arrays were first confirmed by Northern blot studies. Comparison of growth and susceptibility to sodium hypochlorite of mono- and dual-species biofilms of Fusobacterium nucleatum and Peptostreptococcus (micromonas) micros. Preretinal neovascularization has been previously observed in neonatal rats with spontaneously occurring diarrhea. The reciprocal expression of uPA and tPA during follicular development are consistent with the notion that these proteases have different biological functions in the ovary, i.e. A recommendation for modifying the standard analytical method for the determination of chlorine in air. Expression and hormonal regulation of the high-density lipoprotein (HDL) receptor scavenger receptor class B type I messenger ribonucleic acid in the rat ovary.

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Three days after MCAO, either adenovirus-expressing HB-EGF (Ad-HB-EGF) or Ad-LacZ, the control vector, was injected into the lateral ventricle on the ischemic side. Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis. Hypothalamic phospholipids and the function of the human hypothalamopituitary-adrenal cortex system. Detrusor contractility, obstruction grade, maximal voiding detrusor pressure (pdet(max)), detrusor pressure at peak flow (pdet Qmax) and peak flow rate (Qmax) determined by both methods were compared. After pneumoperitoneum has cardura xl tabletki o zmodyfikowanym uwalnianiu 4 mg 30 szt been reestablished, the ileorectal anastomosis is performed laparoscopically using a double-stapling technique. The effects of these two factors were investigated in three developmental stages in male rats: juvenile, post-pubertal, and adult. DASH diet lowers blood pressure and lipid-induced oxidative stress in obesity. The experimental rate differences between isomeric pairs of vinylcyclohexadienes can be explained by comparing reactant destabilization when a bulky group occupies the Z position of the starting alkene and transition state stabilization when a bulky group is endo in the cycloaddition TS. Due to the stereological problems inherent in the data a statistical analysis that concentrates on the evaluation of area fraction will provide clear results whereas the analysis of focal transection density and size distribution can produce misleading results. New cases of breast cancer, using Read codes to confirm diagnoses.

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As a reporter for gene expression studies in maize, R is unique because it can be quantified in living tissue simply by counting the number of pigmented cells following bombardment. Healthcare decisions and product labeling: results of a consumer comprehension study of prototype labeling for proposed over-the-counter cholestyramine. Clutch size in birds: outcome of opposing predator and prey adaptations. Inhibition of these proangiogenic mechanisms has become a major challenge for the development of anti-cancer treatment modalities. The following questions were addressed: would the introduction of vaginal microbicides substantially reduce the risk of female sex workers (FSWs) acquiring HIV?. Identified by agarose gel electrophoresis, the target gene fragment had the same molecular size (3.6 kb) as it was predicted, and it indicated that pcDNA-3gtfB was correctly transcribed into mammalian cells. Some peptides were obtained, in low yields, that appeared to be homologues of more major ones. Concentration of selected microelements in blood serum in malignant gastroenteric tumors in humans. At 24 h after I/R, renal cortical blood flow was measured using a CCD video camera, and the kidneys were harvested for the study.

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Effects of chronic stress on pituitary hormone release induced by combined hemi-extirpation of the thyroid, adrenal and ovary in rats. The level of neuraminic acid in the saliva of newborns and young infants. Serotypes of strains of avian mycobacteria isolated from humans and animals. Cell morphology and DNA fragmentation assays were used to confirm increased apoptosis as a result of TNF treatment. Further, inconvenient dosing regimens, difficulties with metered-dose inhalers, and fear of potential side side effects of stopping cymbalta 30 mg effects have all contributed to poor patient compliance. This indicates that at higher drug concentrations, inhibition is occurring by some mechanism other than those previously postulated.

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A kinetic basis for T cell receptor repertoire selection during an immune response. Substituting lysine for the equivalent asparagine in the beta, epsilon, or delta subunits does not affect the kinetics of receptor activation or apparent agonist affinity. These results support the idea that alveolar bone osteoclasts are able to internalize dying apoptotic bone cells. INDUSTRIAL SOLVENTS AS POSSIBLE ETIOLOGIC AGENTS IN MYELOID METAPLASIA. We also demonstrate that cholinergic activation of alpha 7-containing nAChRs on the subgranular interneurons of the hilus can produce methyllycaconitine-sensitive GABAergic inhibitory postsynaptic currents (IPSCs) in nearby granule cells and enhance the amplitude of an electrically evoked monosynaptic IPSC.

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After exposure to varying levels of shear stress, there were significant variations in gene transcription levels across human mesenchymal stem cells derived from four individual donors. Microbial hydantoinases--industrial enzymes from the origin of life?. The aim of this study was to determine the course motrin 600 mg side effects of diurnal rhythms of blood pressure and heart rate in a group of workers exposed to various intensities of radiofrequency electromagnetic fields. In this model, asphaltene aggregates are described as composed of an aromatic core formed by stacked aromatic sheets surrounded by aliphatic chains. Cancer disease predictive diagnosis: BAT/CD3-positive lymphocytes in cancer patients. We found that the opioid antagonist naloxone completely antagonized both placebo analgesia and the concomitant reduced heart rate response, whereas the beta-blocker propranolol antagonized the placebo heart rate reduction, but not placebo analgesia. None of them had an organic obstruction or had had previous gastrointestinal surgery.

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Papyriflavonol A was found to inhibit human group IIA and V sPLA(2)s potently and irreversibly in a dose-dependent manner, with respective IC(50) values of 3.9 and 4.5 microM. chagasi infection caused an increase in biologically active TGF-beta in human macrophage cultures without changing the total TGF-beta. A rhoptry-protein-associated mechanism of clonal phenotypic variation in rodent malaria. Sources of resistance and its overcoming in group therapy of adolescents with conduct disorder. Although the carcinogenicity of PhIP is not yet known, the metabolic data suggest that PhIP will be carcinogenic in this species. Melanoma cells exhibit variable signal transducer and activator of transcription 1 phosphorylation and a reduced response to IFN-alpha compared with immune effector cells. Transcatheter uterine arterial embolisation is an option in haemodynamically stable patients, and it appears to be the treatment of choice. The CYP2C9 and VKORC1 polymorphisms are differently distributed according to self-declared ethnicity or genetic ancestry in the Brazilian general population plus Amerindians. Furthermore, when facial nerve paralysis has developed to more than House-Brackmann grade III, an immediate operation is recommended to obtain a good postoperative facial functional recovery.

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Here, we show the in vitro reconstitution of the phosphorylation-dependent ubiquitination of I kappa B alpha with purified components. Seminal composition and sexual activity after castration and testosterone replacement in rabbits. Alteration of the radiation-induced changes in wound contraction, collagen synthesis and wound histology by ascorbic acid was studied in mice exposed to 10, 16 and 20 Gy of fractionated (2 Gy/fraction) gamma radiation ultram er cost . These observations suggested that larvae use their foreguts to remove MF from the exuvial space. Plasma concentrations of bosentan were measured up to 5 h post-dose. Measurement of solar spectra relating to photosynthesis and solar cells: an inquiry lab for secondary science.

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