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Bexomer (Eszopiclone)
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Bexomer

Bexomer is a sedative medication. It affects chemicals in human brain that may become unbalanced and cause sleep problems (insomnia). Bexomer is used to treat insomnia: it causes relaxation to help you fall asleep and stay asleep. EsBexomer may also be used for purposes other than those listed here.

Other names for this medication:
Bexomer, Eszopiclone, Fulnite, Zolnite, Zopimin, Zopipure

Similar Products:
Prilosec, Atarax, Trandate, Aristocort, Nizoral, Pepcid, Luvox

Also known as: Eszopiclone

Description

Bexomer along with other Z-drugs are the most commonly prescribed sedative hypnotics in the United States. Eszopiclone is not marketed in the European Union following a 2009 decision by the EMA denying it new active substance status, in which it ruled that eszopiclone was too similar to zopiclone to be considered a new patentable product. Eszopiclone is now available in a generic form in the United States as of May 2014. On May 15, 2014, the USFDA asked that the starting dose of Bexomer be lowered from 2 milligrams to 1 milligram after it was observed in a study that even 8 hours after taking the drug at night, some patients were not able to cope with their next-day activities like driving and other activities that require full alertness. It works by interacting with the GABA receptors.

Bexomer is slightly effective in the treatment of insomnia where difficulty in falling asleep is the primary complaint. Kirsch et al. found the benefit over placebo to be of questionable clinical significance. Although the drug effect and the placebo response were rather small and of questionable clinical importance, the two together produce a reasonably large clinical response. It is not recommended for chronic use in the elderly.

Dosage

Usual Adult Dose for Insomnia:

Initial dose: 1 mg orally once a day immediately before bedtime Maintenance dose: 1 to 3 mg orally once a day immediately before bedtime Maximum dose: 3 mg/day Comments: -The lowest effective dose should be used. -Patients should be monitored for cognitive and/or motor impairments, especially if this drug is used repeatedly. -Patients should be reevaluated if insomnia persists after 7 to 10 days of treatment.

Usual Geriatric Dose for Insomnia:

Initial dose: 1 mg orally once a day immediately before bedtime Maintenance dose: 1 to 2 mg orally once a day immediately before bedtime Maximum dose: 2 mg/day Comments: -The lowest effective dose should be used. -Patients should be monitored for cognitive and/or motor impairments, especially if this drug is used repeatedly. -Patients should be reevaluated if insomnia persists after 7 to 10 days of treatment.

Detailed Bexomer dosage information

Overdose

According to the U.S. Prescribing Information, overdoses of Bexomer up to 90 times the recommended dose have been reported in which the patient fully recovered. According to the May 2014 edition of the official U.S. Prescribing Information, fatalities have been reported only in cases in which eszopliclone was combined with other drugs or alcohol.

Texas poison control centers reported that during 2005–2006 there were 525 total Bexomer overdoses recorded in the state of Texas, the majority of which were intentional suicide attempts.

If consumed within the last hour, Bexomer overdose can be treated with the administration of activated charcoal or via gastric lavage.

Storage

Store Bexomer at room temperature away from moisture and heat.

Keep track of how many capsules have been used from each new bottle of this medicine. Bexomer is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Side effects

The most common side effects associated with Bexomer are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Bexomer if you are allergic to eszopiclone, or if you have ever taken sleep medicine and engaged in activity you later don't remember.

Bexomer is not approved for use by anyone younger than 18 years old.

To make sure Bexomer is safe for you, tell your doctor if you have ever had:

liver disease; a breathing disorder; depression, mental illness, or suicidal thoughts; or drug or alcohol addiction.

Tell your doctor if you are pregnant or breast-feeding.

The sedative effects of eszopiclone may be stronger in older adults. Accidental falls are common in elderly patients who take sedatives. Use caution to avoid falling or accidental injury while you are taking Bexomer.

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