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Betanate (Clobetasol)

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Betanate contains clobetasol, which is a topical corticosteroid. It is used for the treatment of auto-immune skin disorders such as psoriasis, lichen planus, discoid lupus erythematosus, and eczema.

Other names for this medication:
Agiclob, Betalic, Betanate, Clobadis, Clobecos, Cloberis, Clobesym, Clobet, Clobetamil, Clobetasol, Clobevate, Clobex, Clobezine, Clobquad, Clomad, Clomax, Clomic, Clonate, Cloriv, Clotof, Clovate, Cortaz, Cosvate, Covate, Cutivate, Cvate, Eavone, Ecziclo, Embeline, Etavone, Gracederm, Hinate, Isovate, Kloryl, Klosol, Magclo, Miclogenta, Miconit, Monosol, Salyco, Sonaderm, Steriderm, Taxalic, Tenovate, Tigerderm, Topifort, Topisal, Zincoderm

Similar Products:
Zithromax, Rulide, Aygestin, Sildigra, Evista

Also known as: Clobetasol


Generic Betanate is an effective topical (applied to the skin) corticosteroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling. Generic Betanate is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Generic Betanate is also used to treat moderate to severe psoriasis. Generic Betanate may also be used for other purposes. Generic name of Generic Betanate is Clobetasol. Brand names of Generic Betanate are Clobevate, Clobex, Cormax, Embeline E, Olux, Olux-E, Betanate.


This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Betanate E. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it into your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment. Do not miss any doses.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor first before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms, or if you have skin thinning, unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it. With the foam, do not dispense directly from the can into your hands, unless the hands are the affected area. Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to.

To use the foam, scalp solution, or shampoo:

Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently. Do not cover the scalp (eg, shower cap, bathing cap) while it is being treated. With the shampoo, do not wet your hair before using it. And if the shampoo gets on any part of your body other than your scalp, rinse the area well with water. Do not use the shampoo for more than 4 weeks, and the foam and scalp solution for more than 2 weeks unless your doctor told you to.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For redness, itching, and swelling of the skin: For topical dosage forms (cream, gel, or ointment): Adults—Apply to the affected area of the skin 2 times per day. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 12 years of age—Use is not recommended. For topical dosage form (lotion): Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. For plaque psoriasis: For topical dosage form (cream): Impoyz™: Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. Betanate®: Adults and children older than 16 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 16 years of age—Use is not recommended. For topical dosage form (foam): Adults—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (spray): Adults—Spray directly to the affected area of the skin 2 times per day. Children—Use is not recommended. For scalp problems: For topical dosage forms (foam or scalp solution): Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (shampoo): Adults—Apply to the affected area of the scalp once a day. Children—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

High doses or long-term use of Betanate can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the foam can or spray bottle at room temperature, away from heat, flames, smoke, and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store the Betanate® E cream at room temperature, away from heat, moisture, and direct light. Do not refrigerate. Keep Betanate® E cream and Impoyz™cream from freezing.

Detailed Betanate E dosage information

Side effects

The most common side effects associated with Betanate are:

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Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of clobetasol topical in the elderly. However, elderly patients are more likely to have unwanted effects, which may require caution and an adjustment in the dose for patients receiving clobetasol topical cream, foam, gel, lotion, ointment, scalp solution, shampoo, or spray.

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We have examined the effect of human alpha-fetoprotein (h-alpha FP), at concentrations ranging from the physiological to pathological circulating levels, on the native and alpha IFN- and IL2-boosted NK activity of normal peripheral blood lymphocytes (PBL). However, during a disease process, these systems may act aberrantly, and either fail to convert ROS and RNS to harmless substances or by producing more oxidants. Airway compromise necessitating tracheostomy was documented in 26 patients prior to radiotherapy and 3 patients during radiotherapy. Lymphocyte responses to peptide M and to retinal S-antigen in uveitis patients. Influenza viral filaments up to 30 microm in length were observed to form at high levels on surfaces of various polarized epithelial cell types infected with the A/Udorn/72 virus. Novel C-5 aminomethyl pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases.

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Furthermore, the results suggest that the 425 kD glycoconjugate contains sialated galactose-N-acetylgalactosamine oligosaccharides which are O-linked to the protein backbone. The majority of RPDs stated that their residency programs do not currently have a chief resident position. We evaluated the involvement of reactive oxygen species and antioxidant defenses during intestinal remodeling and tail regression of tadpoles of Xenopus laevis. Adenocarcinoma of sweat glands of the footpads was diagnosed in 2 cats. 2d Symposium of the French Society of Enteral and Parenteral Nutrition. Holmium laser ablation of recurrent strictures of urethra and bladder neck: preliminary results. Invasive aspergillosis (IA) is a disease of the immunocompromised host and generally caused by the opportunistic fungal pathogen Aspergillus fumigatus. The current methods for evaluation of the bladder and its outlet are reviewed, focusing on the predictive value of preoperative testing to determine which patients require cystoplasty and an outlet modifying procedure. The aim of our study was to develop and compare the biological performance of two types of biodegradable SN-38 loaded nanoparticles (NPs) with various surface properties, composed of low and high Mw triblock PLGA-PEG-PLGA copolymers, applying rational quality and safety by design approach. Ischemia-reperfusion injury of carotid artery could result in atheroma in rats, this model could be used for future research on the pathogenesis of atherosclerosis.

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These results improve our present understanding of VEEV induced inflammation in mouse brain. The delayed-type hypersensitivity (DTH) reaction to purified protein derivate (PPD, tuberculin) was used as a measure of antigen-specific T-cell reactivity, and subcutaneous immunization with influenza vaccine was employed to evaluate T-cell-dependent B-cell function. In the present study, four experiments were conducted in which the effect of acute, short-, or long-term exposure to selenium was assessed. Renal length as measured on sonography is fundamental in the evaluation of renal disease in children. Delayed neurological dysfunction after a brachial plexus injury is uncommon. Sildenafil has been found to improve exercise capacity and haemodynamic parameters in patients with various pulmonary disorders. The turnover of mineralized growth plate cartilage into bone may be regulated by osteocytes. Where the effect of the two factors is interactive rather than independent is at the point where growth ceases--the growth/no growth interface. The lowered blood pressure might benefit from the predictive adaptive response to prenatal inflammation. The therapeutic use of stored blood and blood substitutes indications and contraindications.

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Inhibition of PLC activity by U73122 was quantified by measuring the decrease of inositol 1,4,5-trisphosphate (InsP(3)) levels. In acrosyringia and dermal eccrine ducts, the luminal cells exhibited intense staining for CKs 1/10/11 and 19. The stimulatory effect was abolished by bilateral section of both the vagi and the sinus nerves. HZwint-1 thus appears to associate with all active centromeres, implying that it plays an important role in correct centromere function. Precipitin reactions apparently not involving specific antibodies were obtained in immunodiffusion experiments performed at low salt concentration between IgG and the muscle proteins, actin and tropomyosin. All substance-related hospitalizations during fiscal year 2005 were identified in the VA National Psychosis Registry (13,402 hospitalizations among 8,813 individuals) and in a random sample of VA patients without serious mental illness (689 hospitalizations among 508 individuals).

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