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Beltrax (Methotrexate)

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Beltrax is a chemotherapy agent and immune-system suppressant. It is used to treat cancer, autoimmune diseases, and ectopic pregnancy and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, gestational trophoblastic disease, and osteosarcoma.

Other names for this medication:
Alltrex, Beltrax, Biotrexate, Caditrex, Carditrex, Cytotrex, Dermotrex, Folitrax, Imutrex, Merex, Methocip, Methorex, Methotrexate, Metorex, Metrex, Mexate, Neotrexate, Nidtrex, Oncotrex, Onotrex, Plastomet, Remtrex, Rextop, Roxate, Tevatrex, Throtex, Trixilem, Vibzi, Zexate

Similar Products:
Flagyl, Cleocin, Casodex, Persantine, Exelon, Omnicef, Ditropan, Cymbalta

Also known as: Methotrexate


Beltrax is a urinary tract analgesic. It is thought to work by relieving pain on the lining of the urinary tract. Generic name of Beltrax is Phenazopyridine. Beltrax is also known as Phenazopyridine. Brand name of Beltrax is Beltrax.


This section provides information on the proper use of a number of products that contain etodolac. It may not be specific to Beltrax XL. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients.

This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute pain: For oral dosage form (capsules or tablets): Adults—200 to 400 milligrams (mg) every 6 to 8 hours. However, the dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor.

For osteoarthritis and rheumatoid arthritis: For oral dosage form (capsules or tablets): Adults—300 milligrams (mg) 2 to 3 times a day, or 400 or 500 mg 2 times a day. Your doctor may lower your dose to 600 mg once a day. The dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—400 to 1000 milligrams (mg) once a day. Children 6 to 16 years of age—Dose is based on body weight and must be determined by your doctor. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heartbeats or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Beltrax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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The frequency of cybrid colony formation was measured in fusions between enucleated chloramphenicol (CAP)-resistant mouse cells and CAP-sensitive mouse cells in varying ratios. The patient had neither been outside of the country nor ever received blood transfusions. The most significant advantage of this combined spectrometer is that we can independently encode spectral information of a diffuse beam in a 2D plane. Higher helical content for the peptide is also indicated by CD studies on TFE titration. Motor function of the large intestine upon stimulation of duodenal receptors.

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Ineffective contraceptive use and its causes in a natural fertility population in southern Jordan. At age 30, he became unable to open the mouth widely with pain in the left jaw joint. Pulse wave velocity (PWV) is commonly elevated in haemodialysis (HD) patients having cardiovascular diseases. Nuclear changes associated with cellular dedifferentiation in pea root cortical cells cultured in vitro. Rates of response and toxicity vary, however, among the various types of phase 1 oncology trials. Vitamin D in massive doses as an adjuvant to the sulfones in the treatment of tuberculoid leprosy. On the prevention of feto-maternal erythrocytic transfusions with citrobioflavonoids and ascorbic acid in homo-specific pregnancies.


Inhibition kinetic determination of trace amount of iodide by the spectrophotometric method with rhodamine B. Technologic advances (eg, safety-engineered devices) may further enhance safety in the healthcare workplace. These results suggest a possible interaction between PMX2B and other schizophrenia-precipitating factors, increasing the risk of the combined phenotypes. Herniation of the small intestine through the dorsal lumbar musculature, multiple pelvic fractures, sacroiliac subluxation, and a right craniodorsal coxofemoral luxation. Microstructural analysis of a urinary stone as evidence of experimentally observed processes of their formation. At later stages however, sFRP5 expression is down-regulated in the liver and becomes strongly expressed in the region corresponding to the junction between the posterior portion of the stomach and the anterior intestines. SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: implications for cell survival after irradiation. We investigated the binding, uptake and intracellular degradation of immunoliposomes by isolated rat liver macrophages in vitro.

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Beating heart revascularization with minimal extracorporeal circulation in patients with a poor ejection fraction. Thermodynamic characterization of the binding of dCMP to the Asn229Asp mutant of thymidylate synthase. Finding good resources for treating school-age children who stutter. The susceptibility of the CM cultured in vitro at different time points to HIV infection was also determined. Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs. He presented to the emergency department with rapidly progressing sepsis followed by multiple organ dysfunction syndrome. Neuropsychological test performance as a function of the duration of MS-related symptomatology. Treatment with metal chelators may aggravate the encephalopathy.

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Although liquids typically flow around intruding objects, a counterintuitive phenomenon occurs in dense suspensions of micrometre-sized particles: they become liquid-like when perturbed lightly, but harden when driven strongly. maltophilia having a high adsorbing ability for gold was very rapid and was affected by the pH of the solution, external gold concentration, and cell amounts. JOF of the trabecular type is a rare fibro-osseous lesion of the craniofacial skeleton almost exclusively occurring in the maxilla or the mandible. Our data show that CST and motor neuron pathology differentially contributed to the disease. Oedema disappearing after surgery may be an explanation for the results. findings suggest that vitamin D may play a role in the aetiology of OH.

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Increased risk of exposure to hepatitis B infection among butchers sharing knives. Therapeutic effect of caspase inhibitors in the prevention of apoptosis and reversal of chronic cerebral vasospasm. Pancreatic lipase drug delivery with glyceride-containing prodrugs. To set up the dual-indexes sequence analytical method for far-infrared fingerprint in which the dual indexes are common peak ratio and variant ration. We show a subset of cortical formin spots moved in actin-dependent linear trajectories.

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We evaluated the relationship between circulating tumor cells and clinicopathologic findings, compared with that of serum squamous cell carcinoma (SCC) antigen and carcinoembryonic antigen (CEA), in ESCC. A measurement of creep properties of human dura and its substitutes were conducted using biomechanical tests. The purpose of this study was to examine the potential of using a radiolabeled cholesterol ester analog/acetylated low density lipoprotein (AcLDL) conjugate as a diagnostic agent for the early and non-invasive detection of atherosclerosis and for the monitoring of the effects of drug therapy. We performed a retrospective audit of intravenous morphine infusion administered to children in an effort to characterize the relationship between dose and age. An overview of four major principles of the legislation is provided: the elevation of the assessor/care manager role, the emphasis on inter-agency collaboration across the health and social care divide, privatization of service, and support of carers (caregivers). In vitro reduction of endotoxin concentrations with the 5S fragment of immunoglobulin G. Scatter analysis techniques applied to anxiety neurotics from a restricted culturo-educational environment. Electron microscopy of 8 strains of Sporothrix schenckii and 1 strain each of Ceratocystis stenoceras, C. However, lipid profiles in RA are different from those observed in the general population at risk of CV disease, where there is evidence of a positive relationship between disease and high cholesterol levels.

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DNA interactions of bifunctional dinuclear platinum(II) antitumor agents. However, the amount of sulfatides in well-differentiated tumors was significantly greater than that in poorly differentiated tumors, which was confirmed by thin-layer chromatography and immunostaining with a monoclonal antisulfatide antibody. Academy and Congress: NAS Panel Completes Its First Assignment in New Relationship with Congress. A study of the racial ancestry of the Mississippi college Negro. Predominantly these have been dihydroxyphenylalanine (DOPA)-melanin and dihydroxynaphthalene (DHN)-melanin. Detailed analysis of the N1pC/P60 peptidases showed that these proteins define a large superfamily encompassing several diverse groups of proteins. Neuropsychological assessment of competency to stand trial evaluations: a practical conceptual model. Herein, we report our early experience with single-incision laparoscopic inguinal hernia repair in Asia, with both the transabdominal preperitoneal (TAPP) and totally extraperitoneal (TEP) approaches.


NKB exerted only a minor stimulatory action exclusively on CRH release, and SP was ineffective. sonnei by T(3), T(4), and T(7) is specifically inhibited by the homologous somatic antigen but not by the Phase I antigen. VLDL-induced apoptosis of beta-cells involved caspase-3 cleavage and reduction in the levels of the c-Jun N-terminal kinase-interacting protein-1. Theoretical assessment of a severe mandibular hypoplasia in hemifacial microsomia revealed the 3-dimensional (3D) complexity of the deformity for corrective procedures, especially distraction osteogenesis. Calf thymus DNA samples treated with AA and NaBH3CN were analyzed by this method.

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Variations in the embryologic evolution of the vena cava dictate the different venous anomalies that may be encountered in the retroperitoneum. Intrahepatic cholangiocarcinoma has a tendency to disperse intrahepatically and extrahepatically, therefore, resectability is limited and prognosis is generally poor. We also observed dense neuropil labeling in many regions, suggesting that this receptor is localized in dendrites and/or axon terminals. Seven of the 10 patients had received fresh frozen plasma and cryoprecipitate before the administration of rVIIa without effect. A qualitative study consisting of eight focus group discussions and 65 in-depth interviews were conducted with MSM in the two cities. Histologically, there were two vesicles caudally which fused to one vesicle cranially. The patient was referred to us for further diagnostic investigations on a right intrascrotal tumour. Growth hormone secretion in women with hypothalamic, maternal and simple obesity. Large scale purification and properties of supernatant pig heart enzyme.

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American neurosurgeons tend to underestimate the risk of DVT associated with brain tumor surgery and to use mechanical thromboprophylaxis despite the availability of effective pharmacologic antithrombotics. This case, including post-mortem observations, histology, and laboratory diagnosis, emphasizes the necessity of appropriate advice regarding malaria prophylaxis before travel to an endemic area. Skeletal muscle-specific expression of a constitutively active activator of p38, MKK6E, in transgenic mice resulted in enhanced Pgc-1alpha and cytochrome oxidase IV protein expression in fast-twitch skeletal muscles. More recently, in vitro culture studies of both adult and pediatric ITP have shown that some ITP plasmas suppress both megakaryocytopoiesis and thrombopoiesis. Risk factors for maternal mortality: a case-control study in Dakar hospitals (Senegal). The epithelial cells of the kidney tubules were involved in vacuolar dystrophy, and in the medular section there were fibroblastic proliferations with hyperemia. Upgrading nurse education, which came into effect in 1996 with the closure of diploma schools in New Brunswick, is likely to entrench the role of nursing assistants in health care because of the economic value of their work during a period of restructuring and rationalization of health care. Mirex residues in nontarget organisms after application of 10-5 bait for fire ant control, northeast Florida--1972-74. However, supplementation with alpha-linolenic acid did produce a significant but small increase in the proportion of docosapentaenoic acid (22:5n-3) recorded at 39 and 54 weeks. A description is given of bilateral, sectoral retinopathia pigmentosa in a female subject and her eldest son.

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Collectively, the data show that intact PG in sterile human tissue is biologically active and may induce local proinflammatory cytokine production. The introduction of a paediatric medical emergency team (pMET) was accompanied by integration of weekly in situ simulation team training into routine clinical metronidazole flagyl and the use of alcohol practice. Two case reports of giant sigmoid diverticulum associated with diverticular disease of the sigmoid colon are presented. This device has potential utility in the biomedical field within the framework of complete micro-electromechanical systems. Systhesis, phase transformation and photoluminescence properties of Eu:La(1-x)Gd(x)VO4 nanofibers by electrospinning method. The results indicate that N-cadherin expression during retinal development is possibly regulated in part by modulation of its phosphorylation state, the balance of which may determine whether N-cadherin remains stably expressed or is targeted for proteolytically mediated turnover to produce NCAD90. Phosphorylation of the effector complex HOPS by the vacuolar kinase Yck3p confers Rab nucleotide specificity for vacuole docking and fusion.

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Such dietary restraint has been suggested to cause counterproductive effects leading to disinhibited eating. Isolation and characterization of side population cells in human gastric cancer cell line BGC-823. New compound NL-608 (a nutlin analog) induces apoptosis in human breast cancer MCF-7 cells. The single site selected for pQCT evaluation in this study did not allow evaluation of the cortical bone compartment. To compare clinicopathological variables, management, and outcome of two cohorts of unselected patients treated for colorectal cancer (CRC) at Christchurch Hospital, New Zealand in 1993-94 and 1998-99. Preparation and clinical use of 99mTc-technetium sulfur colloid for hepatic scintigraphy. This so-called in situ gelation takes place in a very short period of time after contact with the eye tissue due to a change in temperature, pH, or interaction with physiological ions. Despite its more posterior location, ASM can mimic an ovarian cyst or other adnexal cystic mass, and in the obstetric patient can present a mechanical obstacle to delivery with a risk of rupture and infection during labor and delivery. Galphaq-containing G proteins are proposed to be a prominent signaling pathway, and the availability of knockout mice deficient of this subunit has allowed for an investigation of its potential role in airway function. Two membrane-anchored heptapeptides have been prepared and their pore-formation behavior in phospholipid bilayer membranes has been found to differ profoundly as a result only of alkyl chain length.

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Multiple mating by social insect queens increases the genetic diversity among colony members, thereby reducing intracolony relatedness and lowering the potential inclusive fitness gains of altruistic workers. The detection limit for the tryptic digests of alpha- and beta-caseins is approximately 50 fmol. The 22.6 kDa antigen is a tegumental protein of unknown function, restricted to schistosomes. Modification without impact: a case study in nizoral medicine clinical assay failure due to lipemia. The cardiometabolic syndrome and sarcopenic obesity in older persons. Overall outcomes from management of poor-risk breast cancer remain poor, however, and it is possible that some selected subgroups of patients may benefit from such an approach. Okadaic acid (OA) magnified the OZ-triggered O2--production 3.3-fold at 1 microM, but inhibited it completely at 5 microM. Extracellular recordings were obtained from neurones of the thalamic nucleus ventralis postero-lateralis (VPL) in normal rats and those which had sustained a contusive spinal cord injury to the thoraco-lumbar junction 7 days previously. The eluted antibody was used to detect the antigen on monocytes, lymphocytes, and lymphoblastoid cell lines. These techniques may be used to examine the pre-synaptic mechanisms involved in control of motoneuron activity during on-going motor tasks in man without the need for imposed and artificial perturbations of the system.

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Based on a thorough review of the previously reported cases, it is reasonable to consider that CD is inherited in autosomal dominant fashion through a CD gene (PTEN) containing a germline mutation, and that the occurrence of LDD is predicted on an additional somatic hit on the remaining normal CD allele or another unknown gene. In search of the ideal essay for blood thyroglobulin determination in the followup of patients with differentiated thyroid cancer. The forensic efficiency values demonstrate that especially DXS101 and DXS8377 are highly informative markers for kinship analysis and deficiency cases. These findings suggest that femoroacetabular impingement associated with paediatric hip disease can be treated safely by arthroscopic techniques. Compartment syndrome in parenteral drug addicts: report of 2 cases. Including extensor mechanism disruption in the differential diagnosis, and careful attention to key physical findings in the examination of all acutely injured knees, will ensure that this important injury is not overlooked. The findings of this study support an inverse association between NSAID use and risk of lung cancer, but do not suggest a causal relationship. A comparative assessment of univariate longevity measures using zoological animal records. These results indicate that all four methods of suspending the ureteric segments produce contractile responses sensitive enough to study the action of various neurotransmitters. MICs for 100 isolates of pathogenic molds belonging to 12 species were determined by a broth microdilution adaptation of the method recommended by the National Committee for Clinical Laboratory Standards.

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Laparoscopic management of suspicious ovarian cysts in elderly, postmenopausal women. Baclofen-loaded microspheres: preparation and efficacy testing in a new rabbit model. The infection with gillworms (Dactylogyrus sp.) causes severe problems in the keeping and breeding of tropical ornamental fishes, e.g. Consultations with stakeholders for ideas and resources should be encouraged. To analyze the function of these EII genes, they were inactivated via homologous recombination and the resulting mutants characterized for sugar utilization. Results suggest that in the salt-tolerant rice cultivar Pokkali, ADC enzyme activity increases and its transcript also accumulates during the prolonged salinity stress, this mechanism is absent in the salt-sensitive rice cultivar M-1-48 where a prolonged period of salinity stress down-regulates both ADC activity and its transcript level.

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Radiation-induced suppression of the Bmp2 signal transduction pathway in the pluripotent mesenchymal cell line C2C12: an in vitro model for prevention of heterotopic ossification by radiotherapy. Only 1 patient with clinically active autoimmune inner ear disease had a normal positron emission tomography before and after therapy (the HSP-70 was positive before therapy and negative after the therapy). Contrary to men and healthy controls there was no link between CRP and depressive symptoms in women with CHD. NFkappaB DNA binding activity was assessed by electrophoretic mobility shift assay and inhibitor of NFkappaB (IkappaB) kinase (IKK) activity by immunocomplex kinase assay. Production of ligand-specific mutants using a yeast two-hybrid mating assay. In vitro activation of trypsinogen can be detected when pancreatic acini are exposed to a supramaximally stimulating dose of cerulein. In MBEC4 monolayers, a 12 h exposure to TGF-beta1 (1 ng/ml) significantly facilitated the BBB functions, this facilitation being blocked by SB431542. The results suggested that the pantoate supply may be rate-limiting or regulating pantothenate synthesis in leaves. The method of microscopy was found to be reliable in excluding steatorrhoea in children over the age of 3 months. In this study, the biological parameters and 3H-thymidine incorporation caused by 65 MeV protons were adalat drug action more severe than those caused by 137Cs gamma-rays.

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Vertebral body (VB) deformities have been associated with increased patient morbidity and mortality rates. Changes in ventilation and dyspnea per unit changes in work rate albendazole dose pinworms and metabolic variables were similar in the three groups. When transiently expressed in COS-7 or stably expressed in LDL receptor-deficient CHO cells, the receptor mediates endocytic uptake of high density lipophorin (HDLp), an abundant lipoprotein in the circulatory compartment of insects. In this article, the authors discuss the basis behind analysis of continuous data with use of paired and unpaired t tests, the Bonferroni correction, and multivariate analysis of variance for readers of the radiology literature. The programmed cell death induced by these agents involved CPP32 mediated PARP cleavage and DNA fragmentation. Our objective was to evaluate the difference in lifetime discounted net tax revenue generated by RV vaccinated and unvaccinated cohorts from the Egyptian government perspective. Wide-angle x-ray scattering quantified fiber orientation at 0.5-mm intervals across seven non-glaucoma post-mortem human sclerae, and five sclerae with glaucoma history and confirmed axon loss. Intestinal permeability increases early in the course of acute pancreatitis and is associated with sepsis and organ failure. Bronchial pressure measurements in patients with tracheobronchial collapse. Interspecifc variation in eye shape and retinal topography in seven species of galliform bird (Aves: Galliformes: Phasianidae).

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Human umbilical vein EC grown to subconfluence were stimulated with IL-10 (10 ng/ml) and/or IFNgamma (100 U/ml) for 24 h. Principles underlying the projective techniques of personality measurement. High-throughput screens of the gene function provide rapidly increasing amounts of data. Serum lipids, and cardiovascular, anthropometric, and related findings in Japanese and Hawaiian men. In immune system, c-Maf transactivates IL-4 promoter, and ectopic expression of c-Maf skews primary T cell response toward the Th2 pathway. Macrophages play diverse roles in episodic T cell-mediated inflammatory diseases such as multiple sclerosis and rheumatoid arthritis, function as accessory cells for T cell activation, as pro-inflammatory cells, as effector cells which mediate tissue damage, and as anti-inflammatory cells which promote wound healing. Experiments on small animals using automated morphometric methods usually require expensive measurements with ultra-high field dedicated animal MRI systems. In these patients xenografts are showing only a slow degeneration. Accumulation of organochlorine pesticides from water using triolein embedded cellulose acetate membranes.

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The detailed morphological analysis of the malformed spermatids shows that in most cases only the differentiation of the acrosome granule is interfered with. Women aged 20-49, working as cleaners, seamstresses, nursing, kitchen, or shop assistants in 1980 were followed until 1990 or until receiving disability pension. Acute epididymitis following treatment of acute gonorrheal urethritis. However, the World Health Organization (WHO) has recently labelled H. Money, a mediation in the relations between nurses and elderly persons. This characteristic may render the bimonthly schedule particularly attractive for future phase II trials of DCT in combination with other antineoplastic agents. To demonstrate the efficacy of sacral neuromodulation and compare voiding-related health care utilization costs before and after receiving an implant. In the latter, Fos-LI was localized in the nucleus and perikarya of neurons in the grey matter, notably the large motor neurons in the ventral horn.

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Comparative study of protozoan communities in full-scale MWTPs in Beijing related to treatment processes. The up-regulation of vascular endothelial growth factor in mutated Ha-ras HaCaT cell lines is reduced by a farnesyl transferase inhibitor. Role of Golgi Apparatus in Sorogenesis by the Cellular Slime Mold Fonticula alba. Left ventricular outflow tract obstruction secondary to a rhabdomyoma. Career goals: pleasing the customer is as important as picking up a paycheck. C-reactive protein strongly correlated with the levels of serum VEGF independently of platelet and leukocyte counts, even in cancer patients.

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