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Baclof (Baclofen)

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Baclof is a commonly used muscle relaxer for the treatment of muscle spasms. It can be helpful for people with multiple sclerosis or spinal cord problems. Baclof is a muscle relaxant, but experts aren't exactly sure how it works. They believe it stops muscle spasms by calming down overactive nerves in the spinal cord.

Other names for this medication:
Bacfen, Baclof, Baclofen, Bacmax, Chinofen, Liofen, Parafon, Riclofen, Spinofen, Spinospas, Tefsole

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Also known as: Baclofen


Intrathecal baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, cerebral palsy, or certain injuries to the spine. Intrathecal baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Intrathecal baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is delivered by a drug pump directly into the spinal fluid of your back. A doctor will surgically place the pump and monitor the dose of the medication that is delivered by the pump. The dose of intrathecal baclofen will be different for different patients and will depend on the type of muscle tightness that you have.

Intrathecal baclofen is given only by or under the direct supervision of a doctor.


This section provides information on the proper use of a number of products that contain baclofen. It may not be specific to Baclof Double Strength. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, or do not take it longer than your doctor ordered.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For muscle relaxation: For oral dosage form (solution): Adults and children 12 years of age and older—At first, 5 milliliters (mL) three times a day for 3 days. Your doctor may increase your dose by 5 mL every 3 days as needed and tolerated. However, the dose is usually not more than 80 milligrams (mg) per day (20 mg four times a day). Children younger than 12 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults and teenagers—At first, 5 milligrams (mg) three times a day. Your doctor may increase your dose by 5 mg every 3 days until the desired response is reached. However, the dose is not more than 80 mg per day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Baclof and you don't feel good you should visit your doctor or health care provider immediately.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid in the refrigerator. Do not freeze.

Detailed Baclof dosage information

Side effects

The most common side effects associated with Baclof are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Glucagon stimulated IGF-I mRNA levels 1.8- to 2.0-fold, whereas bGH stimulated IGF-I mRNA levels 2.0- to 2.5-fold. Perspective highlights on biodegradable polymeric nanosystems for targeted therapy of solid clarinex cost usa tumors. A technique to study the bacterial colonization of surfaces employing chemotaxis chambers and scanning electron microscopy. Spontaneously hypertensive rats were subjected to bilateral carotid artery occlusion with simultaneous hypotension for 8, 14, or 20 min. Genes putatively encoding cyanophycin synthetase homologues were not identified in the genomes of Eukarya and Archaea and are therefore obviously only occurring in Eubacteria. The entropy effect and thermal stability should render SM a more preferred raft constituent than saturated diacyl glycerophosphocholine. In the current study, we observed peripheral glial cells expressing SOX10, SOX9 and S100B as early as 9 weeks of gestation (W9) in all three neuronal domains. Chronic alcoholism is associated with cognitive and motor deficits, and there is evidence for reversibility with sobriety. Panel recommends White House coordinates AIDS vaccine development. Pretreatment of LEW rats with the monoclonal antibody, MAbS2.4.C5, which defines an epitope in S-antigen, has been shown to effectively inhibit the subsequent induction of EAU with S-antigen.

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cellular absorption and also anti-tumor effects. The composites were prepared by photopolymerization of poly(ethyl acrylate) and other acrylate formulations in a high surface-area rigid glass matrix with 40-A interconnected pores. The recombinant coccidial antigen, designated MA16, is a 125-kDa beta-galactosidase fusion protein, representing about 10 kDa of parasite protein. False recognition of gross gynecological invasive emergency: the role of three-dimensional ultrasound imaging. The vast majority of the research has examined heterosexual marriages, yet there has been rapid evolution in society of cohabitation patterns, who can marry, and roles in marriage. Orthogonal factors of cardiac intervals and their response to stress. These results with different CD8 clones suggest that GVHD and prevention of rejection could be separable effects mediated by distinct populations of donor T cells that recognize recipient alloantigens.

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To develop and validate an easily procured objective estimate of the cell density of the superficial epithelial cells of the normal bulbar conjunctiva using conjunctival impression cytology (CIC). A single-step method for the enrichment of murine peripheral blood eosinophils. Clinical manifestations, diagnostic studies and management of chlamydial pneumonia were reviewed in 115 infants and compared to those from 21 infants with interstitial pertussoid eosinophilic pneumonia. We obtained the population size, age structure of children aged 15 or under, the class and school distribution from Shenzhen Education fenofibrate tricor 145 mg oral tablet Bureau. Helicobacter pylori of remnant stomach and optimal dose of amoxicillin for eradicating Helicobacter pylori.

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Phase II trial of gemcitabine combined with cisplatin in patients with inoperable biliary tract carcinomas. Moreover, NMR data and the chemical modification of cysteine residues demonstrated that the RFP141C peptide binds to two zinc atoms in a cross-brace arrangement. Blood storage in CPD-adenine supplemented with 25 mM inosine and 10 mM phosphate gave 2,3-DPG levels as high as 140 per cent of what drugs interact with theophylline normal for six weeks of blood storage at 4 C. The chicks that were fed aflatoxin-contaminated diets experienced depressed body and liver weights and their livers manifested various pathological changes. This metabolic abnormality is principally initiated by overproduction and/or decreased catabolism of triglyceride-rich lipoproteins (TRLs) and is a consequence of predisposing genetic variations and medical conditions such as obesity and insulin resistance. Cleavage specificities of individual members of kallikrein family of proteins on synthetic peptide containing the bradykinin sequence. Enzymatic splitting and synthesis of flavin adenine dinucleotide in the p-dimethylaminoazobenzene induced rat liver carcinoma tissue.

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Coronary artery calcification greater than or equal to Agatston score of 100 Hounsfield units (HU) at year 25. Cholecystokinin C-45T polymorphism and smoking cessation in women. Repeated gene transfection impairs the engraftment of transplanted porcine neonatal pancreatic cells. This study will evaluate the implementation of a new online self-management intervention and describe what happens when it is made available to existing National Health Services and patients with type 2 diabetes. The authors believe systemic chemotherapy alone may result in long term disease remission in some select patients with non-AIDS-related CNS lymphoma.

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