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Azinom

Azalides are a class of macrolide antibiotics which contain a nitrogen in the macrolide ring. This imparts different pharmacokinetic properties and is associated with greater stability of the molecule. One such Azalide is the antibiotic Azinom. This medication is a macrolide antibiotic used for various bacterial infections such as infections of the middle ear, throat, bronchus, sinuses, skin and soft tissue. It is also useful in treating pneumonia, typhoid, gonorrhoea, granuloma inguinale and chancroid. It prevents bacterial growth.

Other names for this medication:
Arzomicin, Azicin, Azihexal, Azimac, Azimax, Azithro, Azithrocine, Azitro, Azitrolit, Azitrox, Azromax, Clearsing, Doromax, Doyle, Imbys, Inedol, Macrozit, Naxocina, Neozith, Oranex, Pretir, Ribotrex, Rozith, Simpli, Thiza, Trozocina, Zaret, Zemycin, Zimax, Zitrocin, Zitrolab, Zitromax, Zitroneo

Similar Products:
Rebetol, Diamox, Azulfidine, Ticlid, Suprax, Dostinex, Sporanox

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Also known as: Azithromycin

Description

Azinom is in a group of drugs called macrolide antibiotics. Azinom fights bacteria in the body. Azinom is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Azinom may also be used for purposes other than those listed in this medication guide.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Azinom Tablets and other antibacterial drugs, Azinom Tablets should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Azinom Tablets are a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.

Azinom is an antibiotic used to treat bacterial infections of the nose, throat, lungs, bronchitis, ear, skin, soft tissues, and sexually transmitted genital and urinary infections.

Azinom is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Azinom inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Dosage

This section provides information on the proper use of a number of products that contain azithromycin. It may not be specific to Azinom Tri-Pak. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take Azinom® oral liquid or tablets with or without food.

Shake well the bottle of Azinom® oral liquid before each use. Measure your dose correctly with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Measure the Zmax® extended-release oral suspension with a marked measuring spoon, syringe, or cup. You or your child must take this medicine within 12 hours after it has been mixed with water. It is best to take the Zmax® extended-release oral suspension on an empty stomach or at least 1 hour before or 2 hours after a meal. If your child does not use all of the medicine in the bottle, throw it away after you give the dose.

If you or your child vomits within one hour of taking the Zmax® extended-release oral suspension, call your doctor right away to see if more medicine is needed.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Azinom®. These medicines may keep azithromycin from working properly. However, you can take antacids with Zmax®.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release suspension): For treatment of pneumonia: Adults—2 grams (g) once as a single dose. Children weighing 34 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 grams once a day, taken as a single dose. Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually 60 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. For treatment of sinusitis: Adults—2 grams (g) once a day as a single dose. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension or tablets): For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 30 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 5 to 10 mg per kg of body weight once a day for several days. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of pharyngitis or tonsillitis: Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

If you overdose Azinom and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Azinom overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azinom® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azinom dosage information

Side effects

The most common side effects associated with Azinom are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome: diarrhea; headache; loose stools; nausea; stomach pain; upset stomach; vomiting.

Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; changes in hearing or hearing loss; chest pain; eye or vision problems; irregular heartbeat; muscle weakness; pounding in the chest; red, swollen, blistered, or peeling skin; ringing in the ears; seizure; severe diarrhea; stomach cramps/pain; trouble speaking or swallowing; yellowing of the skin or eyes.

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Regional versus general anesthesia in high-risk surgical patients: the need for a clinical trial. We explain these results in terms of the feeding preferences of these predators. Diagnosis of hypogonadism in boys during their childhood and adolescence. Specifically, CoMFA (comparative molecular field analysis) provided a useful general approach in which to evaluate substrate-enzyme and product-enzyme relationships. All patients diagnosed of the solitary constitutional syndrome (328) in a tertiary-care level teaching hospital between January 1991 and December 1996. Clinical pharmacokinetic and potential toxicity studies on vanadium are also highlighted in this review. Membrane markers and functional properties in vitro of blast cells from the peripheral blood of 2 patients with chronic granulocytic leukemia were studied.

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Fractionated stereotactic radiation therapy in the management of benign cavernous sinus meningiomas : long-term experience and review of the literature. However, some disorders may not be amenable to in utero transplantation and there is need to achieve consensus in order to ensure that the procedure is used appropriately, for the benefit of all. Topical formulations containing a zinc gel may be used to delay or prevent latex sensitivity, especially among health care professionals. Two highly conserved upstream inverted repeat elements, previously implicated in ospC regulation, were not required for ospC expression in B. In order to obtain a complete picture, 2 samples of each elastomer class on the market (polysulphuric, polyether, silicone additives, condensation silicone), a total of 8 products, were tested according to the criteria outlined in ADA 19. Attempts were made to develop a simple and reliable non-destructive virus detection method in live flies. The underlying coronary pathology in cTnT-positive and -negative patients that explains the predictive power of cTnT on prognosis and response to antithrombotic therapy is largely unknown. Quantitative and qualitative differences in serum HBV DNA between HBeAg positive carriers and those positive for anti-HBe. Cloned cDNA encoding bovine rhodopsin has been recombined into an expression vector and cotransfected with an antibiotic resistance plasmid into cultured human embryonic kidney cells. Ataxia telangiectasia mutated protein (ATM) is a member of the phosphatidylinositol-3 kinase (PI3K) family, which has a role in the cellular response to DNA double-strand breaks (DSBs).

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No conclusive effect of incarceration on hazard of HIV infection was found, but there was a suggestion that imprisonment might have been a significant relative risk factor for infection in the later period, when risk behaviour among drug users in the community was reduced. Recombination and amplification of pyrimidine-rich sequences may be responsible for initiation and progression of the Xq27 fragile site: an hypothesis. Abstracts of the Second European Conference on Myasthenia Gravis. Serum creatinine increased to levels exceeding 5 mg/dl in 21 patients, 11 of whom were oliguric. Twelve eyes in six patients were studied by pattern reversal ERG. Extracellularly in both costal and epiphyseal cartilage of irradiated rats, collagen density and matrix granules were reduced, while calcification of the matrix was enhanced. Diagnosis and treatment of severe pediatric pulmonary hypertension. Diabetic ketoacidosis (DKA) is a severe metabolic disturbance of insulin-dependent diabetes mellitus (IDDM) which has a significant effect on amino acid metabolism. Calculating three-dimensional changes in protein structure due to amino-acid substitutions: the variable region of immunoglobulins.

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To describe the extent of condom use at first heterosexual intercourse (FHI) in the general population of Slovenia, identify associated factors and assess the association with subsequent use. The separation of the effects of environmental variability from the impacts of fishing has been elusive, but is essential for sound fisheries management. Direct on-line monitoring of hepatic tissue oxygen tension: a new technique. Based on the EIS experiment workplace, a phantom to simulate the distribution of breast tissue was designed. The authors examined the efficacy of the hyaluronic acid-hyaluronidase (HA-HAase) and BTA-Stat tests to detect and predict bladder carcinoma recurrence and tested their specificity for bladder carcinoma screening. Pharmacokinetics of cetuximab after administration of escalating single dosing and weekly fixed dosing in patients with solid tumors.

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Cold-restraint stress induced protein kinase B/Akt to a similar level in the gastric mucosa of both WT and Jnk1-/- mice indicating the integrity of other signaling pathways. BDNF levels in the ipsilateral to ligation side was significantly higher only in the frontal protonix 20 mg daily cortex of standard as compared to enriched rats. After lyophilizing and re-dispersion, the PCL-PEG-PCL micelles became larger in size compared to as-prepared ones. Advanced glycation end products (AGEs) and their cell surface receptor, RAGE, have been implicated in the pathogenesis of diabetic complications. The principles guiding the development, use and assessment of anti-oxidant therapies are discussed in this review.

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Comparisons were made between W-Pmix and W-Psen, W-Emix and W-Esen, and E-Pmix and E-Psen. During her workup, she was diagnosed with mucinous appendiceal carcinoma and clear cell carcinoma of the kidney. We report a case of a 60-year-old man who presented with hoarseness secondary to a ductus arteriosus aneurysm and underwent a repair of this abnormality via a left posterolateral thoracotomy utilizing partial cardiopulmonary bypass. The gene organization of the two regions indicates that the IB region is evolving at a different pace than the IA region. However, aspirin (ASA) causes damage only when it is given orally. This effect was reversed by adding anti-PSA antibodies but not by interleukin-2. Symptoms were dramatic, and recovery was spontaneous following conservative treatment. The aim of this study is to report on the neuropsychological aspects of teenage patients with attention deficit hyperactivity disorder (ADHD), namely disorders affecting attention, memory, the executive functions and language. Cytologic artifacts and pitfalls of thyroid fine-needle aspiration using ThinPrep: a comparative retrospective review.

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Replication of a para que sirve tramadol normon 50 mg hepatitis C virus replicon clone in mouse cells. We conducted a social survey on gender preferences and potential demand for preconception sex selection among 301 pregnant women in Karachi, Pakistan, using a self-report questionnaire consisting of 14 questions. Delineation errors remain constant during the course of radiation and therefore have a large impact on the dose to the tumor. Promoter A3 was used predominantly at low temperature, whereas A1 or A2 promoters were gradually activated by increasing the temperature. Many of the host proinflammatory genes augmented in HCMV-infected endothelial cells are regulated, at least in part, by the NF-kappaB pathway. Positive correlations between aortic O2- production and SBP, as well as between insulin resistance and SBP or between O2- production and insulin resistance, were found in control, glucose-fed and aspirin-treated, glucose-fed rats. Forty-four children aged 2-9 years with strabismic and anisometropic amblyopia were prospectively followed up during amblyopia treatment. This approach was applied to 8 sediments from French canals contaminated to varying degrees. Circadian periodicity in human heart rate daily variability disorders: subsequent demonstrations through a chronobiological approach to the values of estimated alpha exponent on sinusal R-R intervals.

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This study has shown biologically significant adverse effects at all concentrations tested. The RETISERT intravitreal implant offers sustained local control of inflammation without the systemic side effects that limit standard immunosuppressive and oral corticosteroid therapies. We used biceps vibration to induce illusory forearm extension in 10 participants and measured the aftereffect-perceived movement in the opposite direction. Indeed, leptin levels are positively correlated to indices of body fat, namely total fat mass, percent body fat and body mass index (BMI). Additionally, there is evidence that regular physical activity or exercise can decrease emotional stress, blood pressure, the duration of neutropenia, thrombocytopenia, and pain. This evolutionarily conserved interaction disrupts DIAP1-caspase interactions, unleashing apoptosis-inducing caspase activity. In this study, we examined an acute effect of oral Pi loading on serum FGF23 levels to clarify the role in rapid adjustment of serum Pi level.

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There were no separate subgroups of the RI strain means, and overlapping ranges point to a polygenic genetic determination of the studied behavioral phenotypes. Colour coding, drug administration error and the systems approach to safety. Data on occurrence of other diseases of ophthalmologic importance is presented. 1,25 (OH)2D3, the most active metabolite of vitamin D3, has been shown to be produced by keratinocytes (KC). Spleen cells from DBA/2 mice immunized with high numbers of sheep red blood cells specifically suppress the primary anti-SRBC antibody response of syngeneic recipients specifically suppress the primary anti-SRBC antibody response of syngeneic recipients after in vivo transfer. To determine side effects of extracorporeal photopheresis in the treatment of patients with the acquired immunodeficiency syndrome (AIDS)-related complex, and to gain early evidence of efficacy of the treatment. The pilot-scale process was constructed and has been tested in the rural area of Korea. Present status of and outlook for the development of scientific studies on the prevention, diagnosis and treatment of rickets. Fluorescence of lymphoblasts was dependent upon lectin dose and was eliminated when staining was performed in the presence of N-acetyl-D-galactosamine, the appropriate competitive sugar for VV. A new methodology: the method and technical means for studying the coagulation of blood and the acoustic properties of other biological fluids (ultrasound coagulography) was developed.

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