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Avana (Avanafil)
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Avana

Avana is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012[1] and by EMA on June 21, 2013. Avana acts by inhibiting a specific phosphodiesterase type 5 enzyme found in various body tissues, primarily in the corpus cavernosum penis.

Other names for this medication:
Avanafil, Spedra, Stendra

Similar Products:
Diamox, Prilosec, Mysoline, Retin, Lamictal, Claritin, Requip

Also known as: Avanafil

Description

Avana is FDA-approved anti-impotence drug manufactured by Sunrise Remedies. The active ingredient of Avana is Avanafil, which is classified as PDE5 inhibitor and is aimed to treat male sexual dysfunction. Other well-known agents share a similar mechanism of action as Avanafil: Tadalafil (Cialis), Sildenafil (Viagra) and Vardenafil (Levitra). Once a drug is absorbed into the bloodstream, Avanafil expands muscles in the walls of blood vessels, thereby increases blood flow into the penis and provides a strong erection. The effect of medication starts in 15-30 minutes after taking and can last up to 6 hours, allowing you to choose the most appropriate time for you and your partner. Avanafil helps to achieve an erection when sexual stimulation occurs. Avana doesn't protect you and your partner from sexually transmitted diseases (including HIV) and from pregnancy. Avana is not intended for the treatment in women and children.

Dosage

Take one pill orally with a full glass of water 15-30 minutes before sexual activity. It may be taken with or without food. Start with 50 mg, if you are undergoing stable alpha-blocker therapy or have other health issues. You should not take the medication more than once a day or more than a recommended dose.

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avana are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Avana if you are allergic to Avana's components. Do not take Avana if you are also using organic nitrates, nitrate drug for chest pain or heart condition (e.g., nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate), nitrates as amyl nitrate or nitrite ("poppers"). Do not take Avana if you take other medication to treat erectile dysfunction, pulmonary arterial hypertension, such as riociguat (Adempas). Do not take Avana in case you are taking erythromycin, medicines called alpha-blockers, ketoconazole, itraconazole (Sporanox or Nizoral), ritonavir (Norvir) or indinavir (Crixivan). Try not to consume alcohol while using Avana, as it can lower your blood pressure, causing dizziness and rapid heart rate (tachycardia). Do not drive or operate machinery while taking the medication. Contact you doctor or health care professional right away if the erection lasts longer than 4 hours or if it becomes painful. Avana does not protect you and your partner from sexually transmitted diseases and pregnancy. Avana can be dangerous for children and women.

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However, different structural features control the interactions over different distance regimes and with different consequences. A comparison of total mercury and methylmercury export from various Minnesota watersheds. Susceptibility of the guinea pig to Endamoeba histolytica of human origin. Septic arthritis due to Listeria monocytogenes in a patient receiving etanercept. The pathophysiology of CO2-retention in obstructive bronchopulmonary disease. The heavy chain (HC) of MHC class I was extracted from bacteria under denaturing and non-reducing conditions. Carcinogenesis of head and neck results from a dysregulation of cellular proliferation, differentiation, and cell death. Administration of alendronate increased BMD in postmenopausal women, preventing new fractures in patients with previous fractures. Future studies should attempt to either adjust for or stratify by ethnicity when examining these relationships. 14-3-3 epsilon modulates the stimulated secretion of endopeptidase 24.15.

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As IL-10 was the unique factor able to inhibit IL-12p70 produced by cultured splenic DC, we showed that a neutralizing antibody to IL-10 did not suppress the IL-12p70 inhibitory activity of thymic fibroblast-conditioned medium (FCM). In CDKN2A-positive individuals, family history of CM and presence of atypical nevi, rather than MC1R status, modified risk (20.75- and 2.83-fold, respectively). Role of opioid mu-receptor that has been showed to involve in the insulin-dependent diabetic rats in the induction of insulin resistance remains unclear. Effect of photoperiod and end-of-day light quality on alkaloids and phenolic compounds of tobacco. We emphasize the use of electrodiagnostic studies to investigate patients with back and limb pain for correctly localizing responsible pathology. Compared with patients with standard pacing indications, CRT recipients have less good electrical characteristics in the atrium. In conclusion, an adequate calcium intake may help promote a favorable effect of dietary protein on the skeleton in older individuals. The mammalian suprachiasmatic nucleus (SCN) is a master circadian pacemaker. This lead to incidence estimates of 27.0, 18.6, and 23.3 per 100000 women-years of observation for all benign tumors of the uterus, ovary, and breast respectively. Dynamic morphological changes observed in the respiratory system immediately after craniocerebral trauma.

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Biochemical evaluation of damage due to lead: importance and significance of erythrocyte zinc-protoporhyrin IX and urinary amino acid determination. Zebrafish are small vertebrates whose bodies are composed predominantly of skeletal muscle, making them attractive models for studying mammalian muscle disorders. We investigate the performance of NestedMICA in a range scenario, on synthetic data and a well-characterized set of muscle regulatory regions, and compare it with the popular MEME program. Although in experimental animals combinations have been shown unequivocally to delay the onset of resistance, this has not yet been proved formally in human malaria. Thus, managing posttraumatic aniridia with aphakia by means of haptic fixation of a foldable intraocular lens on a custom-tailored iris prosthesis is a promising approach for visual rehabilitation and cosmetic improvement. High mid-trimester serum AFP values may help in the prediction of severe pre-eclampsia. Reversed causality--a need to revisit systems modeling of work-stress-health relationships. Lis Maternity Hospital and the Sara Racine IVF Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. Detection of myocardial damage by serial measurements of cardiac troponin T, CK MBmass, and TROPT rapid test. Myocardial ischemia, during cardiopulmonary arrest, can lead to atropine-resistant bradyasystole from interstitial accumulation of endogenous adenosine.

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Arterial oxygen saturation and heart rate variation during breath-holding: comparison between breath-hold divers and controls. Comparisons of the deduced amino acid sequence of the partial protein to other known cytochrome P-450 sequences indicate that it is the first member of a new family of cytochrome P-450s, designated CYP63-1A. Ventilation contributes to exertional dyspnea similarly as in lean subjects and in obese patients regardless of OSA. Colorimetry was first employed to measure the actual content of amino acid in Cordyceps sinensis. Possible mechanisms of rupture process as independent unbinding and cooperative unbinding were discussed. There were changes in haematocrit and haemoglobin values in all groups of chronic and acute carbon tetrachloride intoxicated rats xanax pill holder . This study investigates the effects of kyphoplasty on pain and mobility in patients with osteoporosis and painful vertebral fractures compared with conventional medical management.

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