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Aspitrate (Isosorbide)

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Aspitrate reduces your risk of getting heart-related chest pain (angina attack). It does not treat an angina attack that has already begun and should not be used for this purpose. It works by relaxing and widening blood vessels in the heart.

Other names for this medication:
Aspitrate, Dilatrate, Ecosmin, Ismorin, Ismotic, Isoditrate, Isoloprin, Isordil, Isosorbide, Monit, Monoket, Monosprin, Nitren, Nitrofix, Nitroprin, Solosprin, Vasoprin

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Eulexin, Imdur, Zovirax, Crestor, Zetia, Cleocin, Minipress, Calan, Colcrys, Ilosone

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Also known as: Isosorbide


Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). It does not work fast enough to relieve the pain of an angina attack that has already started.

Isosorbide mononitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Angina Pectoris Prophylaxis:

EXTENDED RELEASE: 30 to 60 mg orally once a day in the morning Maximum dose: 240 mg orally once a day in the morning Comments: -Swallow whole (do not crush or chew) with half-glass of fluid. -Start at low end of dosing range for elderly patients. Use: Prevention of angina pectoris due to coronary artery disease; onset of action is not sufficiently rapid to be useful in aborting an acute anginal episode.

Usual Adult Dose for Angina Pectoris:

EXTENDED RELEASE: 30 to 60 mg orally once a day in the morning Maximum dose: 240 mg orally once a day in the morning Comments: -Swallow whole (do not crush or chew) with half-glass of fluid. -Start at low end of dosing range for elderly patients. Use: Prevention of angina pectoris due to coronary artery disease; onset of action is not sufficiently rapid to be useful in aborting an acute anginal episode.

Detailed Aspitrate dosage information


If you overdose Generic Aspitrate and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aspitrate are difficult or slow breathing, muscle cramps, nausea, vomiting, diarrhea, high temperature, fainting, abnormal heartbeat, changes in vision, flushing, convulsions, severe throbbing migraine, lightheadedness.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Isosorbide mononitrate dosage information

Side effects

The most common side effects associated with Aspitrate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of isosorbide mononitrate in the pediatric population. Safety and efficacy have not been established.

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