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Aripicon

Aripicon is an antipsychotic medication. It works by changing the actions of chemicals in the brain. Aripicon is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar I disorder (manic depression).

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole

Description

Aripiprazole injection is used to treat agitation caused by schizophrenia or bipolar mania.

Aripiprazole extended-release injection is used to treat schizophrenia (a mental disorder) and bipolar disorder (manic-depressive illness). It works in the brain to change how certain chemicals affect patients. Aripiprazole is an antipsychotic agent.

This medicine is to be given only by or under the immediate supervision of your doctor.

Dosage

This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Aripicon Discmelt. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Aripicon Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Aripicon Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Aripicon Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Aripicon Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Aripicon® and Aripicon Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Aripicon Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Aripicon® and Aripicon Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Aripicon Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, or fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aripicon Discmelt dosage information

Side effects

The most common side effects associated with Aripicon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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In order to determine an aerobic diving limit (ADL) in emperor penguins (Aptenodytes forsteri), post-dive blood lactate concentrations were measured in penguins foraging at an isolated sea ice hole. Peptides derived from the bee-venom melittin were fitted with the haptenic group dinitrocarboxyphenyl (Dncp) and tested in out-bred guinea pigs for immunogenicity by measuring the IgG anti-Dncp antibody response by ELISA. Adipose tissue endocannabinoids may produce metabolic and endocrine effects, but very few data are available in human adipose tissue and in primary human fat cells. This paper presents contributions concerning HIK SVM for image classification. The densitometric, histological and morphometric analysis showed that the treated ovariectomized animals developed more new bone than the control ovariectomized rats, but no significant difference was observed between the treatment periods. Laparoscopic cholecystectomy (LC) performed for acute cholecystitis (AC) is usually advised within 72 h of symptom onset. Diagnostic guidelines for Kawasaki Disease was revised to meet the present situation in 2002. Selected kinematic, kinetic and spatio-temporal gait parameters were measured at baseline, immediately after the muscle stretch and 24 h later.

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Slowing of gastric emptying by acids does not seem to be dependent upon their pK values provided they are less than 5. This progress in our understanding of the molecular minipress medication dosage pathology has set the stage for clinically meaningful advances in diagnosis and treatment. There was no degradation product observed, on the other hand, with the same condition, the peptides were completely hydrolyzed in 8 h. Green fluorescent protein (GFP) and its mutants have become valuable tools in molecular biology. Lycorine hydrochloride inhibits metastatic melanoma cell-dominant vasculogenic mimicry. Our experience with the patients in this case series supports the contention that there is no simple, uniform approach to the substance-dependent patient with bipolar disorder.

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Monocyte chemoattractant protein-1-stimulated arteriogenesis was strongly reduced in rabbits by application of the FGF inhibitor polyanetholesulfonic acid, indicating that the monocyte-related arteriogenesis (as well as the unstimulated adaptation proper) is promoted by FGFs. Diabetes increases expression of ICAM after a brief period of cerebral ischemia. Rehabilitation of the sexual delinquent with special reference to the homosexually oriented. These risks were grouped into the following problem categories: 1. As unpredictable efficacy and high levels of systemic toxicity are common in cancer chemotherapy, pharmacogenetics is particularly appealing for oncology. Patients with biliary tract cancer who underwent potentially curative resection were identified from the database. Upper sacral deformities appear due to the growth plate response to the changed pressure gradients across the epiphyseal plate rather than interosseous remodeling of the ilium and acetabular area. The results are relevant to the design of locally-resonant acoustic media using soft-lithography techniques with elastomers. Experimental study on robotic milling of oak wood and human temporal bone specimen. It has also emerged as a potential anticancer factor in hepatocellular carcinoma (HCC).

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Preparation of a dansylated fibrate, a new fluorescent tool to study peroxisome proliferation. Here we review research on the often overlooked development of cranial muscles, and on its dependence on cranial cartilage development. The effect of pregnancy and lactation on the absorption of zinc and lysine by the rat duodenum in situ. Invasion of liver tissue by tumor cells and leukocytes: comparative ultrastructure. Clinical features and outcome of chronic dialysis patients admitted to an intensive care unit. Differences in separation methods and variability of the individual may contribute to these variable results. Ultrastructural study of hematopoietic marrow during regeneration after irradiation. Unexplained disabling fatigue in childhood is substantially familial. In this way, the neural biosynthetic activity in all regions studied decreased as the older ages are reached. Systemic sclerosis (SSc) is a systemic autoimmune disease of unknown cause characterized by microvasculopathy, fibroblast activation, and excessive production of collagen, causing tissue and organ damage.

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Magnetic resonance imaging (MRI) and computed tomography (CT) are such new techniques which potentially may provide information pertaining to bone density and structure as well as to occult fracture detection. Unfortunately, the results obtained with this important technique have been disappointing and diverse, which has caused a fair amount of skepticism as to its role. Assessment of haemostasis in platelet transfusion clinical trials with differential follow-up. Determination of total (peroxyl) radical-trapping antioxidant parameter and malondialdehyde concentration in seminal plasma of 112 men attending IVF-ET or intracytoplasmic sperm injection (ICSI) programs. The focus of this study was to understand how Sle2 on murine chromosome 4 impacts the immune system. As demonstrated by these cases, synthetic material may be used in restoration of the carotid artery. Additions of BaO or MgO resulted in an increase in CO2 adsorption capacity of the modified zirconia particles. To critically assess the evidence that appendiceal perforation is a risk factor for subsequent tubal infertility or ectopic pregnancy. Our study shows that only during beta-adrenoceptor stimulation, pharmacological inhibition of the I(Ks) current plays an important role in the APD recorded from isolated ventricular trabeculae and papillary muscles, but not from Purkinje fibers.

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