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Aricept (Donepezil)

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Aricept is used to treat confusion (dementia) related to Alzheimer's disease. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to function. This medication is an enzyme blocker that works by restoring the balance of natural substances (neurotransmitters) in the brain.

Other names for this medication:
Alzil, Aricep, Demenza, Depzil, Donasure, Donaz, Donecept, Donep, Donepezil, Dopezil, Dorent, Nepzil, Nozil, Pezil

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Also known as: Donepezil


{name} (donepezil) improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah SEET il KOE leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.

{name} is used to treat mild to moderate dementia caused by Alzheimer's disease.

{name} is not a cure for Alzheimer's disease. This condition will progress over time, even in people who take donepezil.


The tablet should be dissolved on your tongue and then you should drink water. Do not crush or chew it. The usual dose is 5 mg-10 mg a day. Take Generic Aricept tablets orally with or without food, at the same time every day at bedtime. Take Generic Aricept once a day. If you want to achieve most effective results do not stop taking Generic Aricept suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe nausea, vomiting, drooling, sweating, blurred vision, feeling light-headed, slow heartbeat, shallow breathing, muscle weakness, fainting, or seizure (convulsions).


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Aricept are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Aricept if you are allergic to donepezil or certain other drugs. Tell your doctor if you are allergic to any medicines.

To make sure Aricept is safe for you, tell your doctor if you have:

a heart rhythm disorder; a history of stomach ulcers; an enlarged prostate or urination problems; liver or kidney disease; epilepsy or other seizure disorder; trouble swallowing; or asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder.

It is not known whether Aricept will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether donepezil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Ultrastructural and immunocytochemical analysis of diploid germ cells isolated from fetal rabbit gonads. While some federal policies are complementary, many overlap, illustrating not only the complexity of collaborative efforts on the part of the implementing federal agencies but also the diversity of partnerships supporting adolescent substance use treatment. Nitrogenase mRNA was synthesized from the nifHDK operon during the first 4 h of the dark period under light-dark conditions or during the first 6 h of the subjective-dark period when grown in continuous light. Placental separation from a seat belt injury due to severe turbulence during aeroplane travel. FGF-1 is abundantly expressed in the synovium in rheumatoid arthritis and in rejecting allografts, sites of chronic immune-mediated inflammation. Ferromagnetic and ferroelectric systems show similar curves, which suggests that the above two biological systems are governed by cooperative interactions between adjacent molecular sites. Loss of either Trp53 or Apc leads to the development of columnar metaplasia, whereas loss of Trp53, but not Apc, leads to development of cancer in mice with jejunoesophageal reflux. The anti-12/ 13 kDa IgG and IgG(T) ELISAs gave correlation coefficients with infection intensity of 0.56 and 0.63 respectively. Consequently, when focusing on effects of metal uptake for the organism itself, there is no need to correct for adsorption. Postpartum weight retention occurred in this group of nondepressed women with previous histories of major depression independent of drug treatment.

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Thus, anti-angiogenic drugs may prove most efficacious when they are targeted to specific stages of cancer. Cancer from the outside, aging from the inside: mouse models to study the consequences of defective nucleotide excision repair. Microbiological culture analysis of the tongue anaerobic microflora in subjects with and without halitosis. These patients did not receive long-term preventive antifungal therapy for oral candidiasis, even as secondary prophylaxis against cryptococcosis. These proteins utilize a conserved LXCXE motif, which is also found in cellular proteins, to target the retinoblastoma family. Of 1468 patients with gastric cancer, the next 5-year survival (5YS) of patients who already survived for 1, 2, 3, 4, and 5 years after the initial operation was examined, ie, for patients who have survived 1 year, the 5YS (the 6-year survival from operation) was calculated. To understand the molecular basis of salt-stress response, four subtracted cDNA libraries were constructed employing specific NaCl-stressed tissues from salt-tolerant (CSR 27 and Pokkali) and salt-sensitive (Pusa basmati 1) rice cultivars. The supernatant is subjected to a cleanup using both C18 and graphitized carbon black SPE columns. The method is general for diseases of complex inheritance, and lies within the competence of any serious genetic clinic. To assess whether determinants of violence operate as risk factors, direct protective factors, or both during adolescence and young adulthood.

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(-)Epigallocatechin-3-gallate inhibits gelatinase activity of some bacterial isolates from ocular infection, and limits their invasion through gelatine. The device accuracy has implications for clinical decision-making. An evaluation of the most efficient combinations and of the clinical situations in which combinations show promise of improved results is in progress. Age dependent and tissue specific FMR-1 gene expression in human organs. Nine hundred thirty-seven inner city children 5 to 11 years old with moderate to severe asthma underwent allergen skin testing. Finally, a new vertebrate genetic model, zebrafish, appears very promising for molecular studies. Those complications were stratified by birth weight and analyzed, using bivariate and multivariate techniques to identify specific risk factors. To determine the role played by the tensor veli palatini and levator veli palatini muscles (mTVP and mLVP, respectively) in eustachian tube (ET) opening. Age in relation to worker compensation costs in the construction industry. The Igkappa gene contains an evolutionarily conserved nuclear matrix association region (MAR) adjacent to the intronic enhancer.

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Psychiatry and medical education from the vantage point of 45 years. PCR fingerprinting could differentiate the strains analyzed into 12 different patterns, whereas ribotyping with XbaI, which produced the highest number of patterns, generated only 7 different profiles. Little of the organic N fraction in the biosolids remained available for further mineralization following 48 weeks of incubation. Influence of NG-nitro-L-arginine methyl ester on clinical and biochemical effects of methylene blue in pentylenetetrazole-evoked convulsions. Recent case reports and a few limited studies have suggested that opiates cause dilation of the common bile duct of the abusers.

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This article uses post-earthquake Haiti as a case study to illustrate conditions for women and girls who suffer daily threats of physical, emotional, economic, and social harm in ways that have no direct parallels for their male counterparts. English-language articles were identified through a search of MEDLINE (through December 2004) using the key word bisphosphonate. Clinical study on fluoroquinolone prophylaxis in neutropenia patients with acute leukemia. A survey was administered to male university students who tested positive for high-risk human papillomavirus. A study was conducted to determine the presence of cortisol in body tissue of porcine embryos at days 25 and 35 of gestation. These sedimentation events have left a distinct mixture of hydrocarbons that are represented by C22-C30 n-alkanes with a predominance of the even-carbon-number homologues, high relative proportions of squalane and C16-C24 n-alkylcyclopentanes predominated by n-undecyl-, n-tridecyl- and n-pentadecylcyclopentane. The IL-2 down-regulation may not be an effect of IL-10 upregulation. A reduction in fracture risk of human subjects has not yet been shown in a prospective trial. Managed care has entered the lexicon of healthcare reform, but confusion and ignorance surround its meaning and purpose.

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These data illustrate that multiple signaling pathways, including those of distinct members of the MAP kinase family, mediate the phosphorylation of eIF4E and that the association of eIF4E with 4E-BP1 does not necessarily prevent phosphorylation of eIF4E in vivo. Estrogens and synthetic androgens in manure slurry from trenbolone acetate/estradiol implanted cattle and in waste-receiving lagoons used for irrigation. This study suggests that the NOSs could play a key role in the therapeutic effects of tirapazamine, particularly because NOS activity is markedly increased in several human tumors. These organisms may also cause some community-acquired life-threatening infections, such as bacteraemic urinary tract or intra-abdominal infections. In the present study we have compared five different cell fixation-permeabilisation protocols and nine fluorochrome-conjugated (FITC or PE) monoclonal antibodies (mAb): four mAb directed against Bcl-2 and five against p53. RIGR utilizes a priori data for optimal image reconstruction whereas the SVD method seeks to optimize data acquisition. Bile acid inhibition of interferon activity in human lymphocytes: no evidence of oxidative stress. However, the value of delayed 3 h imaging has not been clarified. Pathologic complete response was a significant prognostic factor for overall survival and the significant predictive factor for a pathologic complete response was pretreatment clinical stage. The solution-phase assay consistently measured autoantibodies to MBP in serum from human subjects with Semple rabies vaccine (SRV)-induced demyelinating disease and from MBP-immunized animals.

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Neuropilins as Semaphorin receptors: in vivo functions in neuronal cell migration and axon guidance. To evaluate the long-term safety and efficacy of alitretinoin for the treatment of CHD. Production of a rabbit anti-cockatiel immunoglobulin G and characterization of its cross-reactivities with immunoglobulin G of other psittacine species. Some of this seems to be in the form of gas bubbles in the glass spheres, but most of it could be in some complex form other than gas. Analysis of pre- to post-training changes to the coupling dynamics in the 1:1 anti-phase task support the hypothesis that acquisition of the 2L:1R pattern involved reorganisation of the inherent dynamics. Marine teleosts, freshwater teleosts, and marine elasmobranchs all utilize different physiologic strategies for osmoregulation. Together, the results provide the first demonstration that HDAC inhibitor trichostatin A inhibits cyclin D1 gene transcription through targeting transcription factor NF-kappaB/p65 DNA binding.

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brucei strains do not differentiate to stumpy forms in the host. Sera taken from the patients with familial hypercholesterolemia before and after ApoB100-directed immuno-apheresis confirmed that ApoB100 inhibited LTA-induced inflammation in humans. The coordinations of all the necessary services with the active participation of social workers, physicians, educators and teachers is crucial for a successful treatment. Tentative method of analysis for carbon monoxide content of the atmosphere (infrared absorption method). Study of the blood flow velocity in the cerebral vessels of patients with primary glaucoma by the method of radiocirculography. Mycobacterium tuberculosis cell envelope is a treasure house of biologically active lipids of fascinating molecular architecture. Hormones integrate the activities of their target cells through receptor-modulated cascades of protein interactions that ultimately lead to changes in cellular function. The eight included trials involved a total of bactrim antibiotic treats what 269 participants from five different countries. While much work remains, the evidence has become strong that IPG generation following insulin action is a significant signaling mechanism.

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The GTA and WGA were not different between preeclamptic patients without FSGS lesion and patients with isolated hematuria. The effects occurred during observation in the ward and were controlled according to the treatment protocol recommended by a German expert consensus meeting on the treatment of anaphylactoid reactions. There has been a revolution in cardiovascular neuroscience in recent years with, in some cases, translation into clinical practice of the knowledge of pathophysiology gained through application of sympathetic nerve recording and catecholamine isotope dilution methodology. Improving delivery of antineoplastic agents with anti-vascular endothelial growth factor therapy. Isocaloric feeding resulted in elevated xenin concentrations in unextracted plasma and after high-pressure liquid chromatography. Photochemical smog systems: effect of dilution on ozone formation. Another source of incoming nerve fibres was found at capsular level, accompanying blood vessels. Although reactive arthritis is an easily managed disease, it is easily missed particularly in young otherwise healthy patients who may not present with classic symptoms.

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Hydronephrosis is an important early indicator of colorectal cancer recurrence, even in the absence of a mass. A avodart medication generic fast thermal-curing nanoimprint resist based on cationic polymerizable epoxysiloxane. Evaluation of conditions for calpain inhibition in the rat spinal cord: effective postinjury inhibition with intraspinal MDL28170 microinjection. Three unique predictors were found for African Americans: never having been married, not living in stable housing, and not being admitted at the index visit. Plaque rupture and thromboembolitic complications are probably higher in the case of lipid-rich lesions. Coverage of localized gingival recessions: comparison of micro- and macrosurgical techniques. Most recently, molecular analysis of these tumors has demonstrated definitively that the serous and mucinous types of cystic neoplasms of the pancreas are unrelated pathogenetically. These results suggest that there are specific patterns of genetic instability common to preneoplastic lesions and the breast cancers that subsequently develop even when the paired lesions are not clonally related. Contralateral control infusions of normal saline were also administered.

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Basically, the aim of the project is to improve the plant by identifying genes involved in responses against stresses that affect domestic production, like drought stress and Asian Rust fungal disease. An immunopurified, polyclonal antibody to the C terminal region of FAAH was used in these studies. FGF-10 showed significant mitogenic activity for primary preadipocytes, but did not affect the differentiation of preadipocytes. Differences between adolescent mothers and nonmothers: an interview study. Severe recurrent hepatitis C after liver retransplantation for hepatitis C virus-related graft cirrhosis. In their study published in Science Signaling (Research Article, 27 March 2012, DOI: 10.1126/scisignal.2002469), Dalle Pezze et al. Newer oxygen technologies will continue to provide improved methods of care for patients with advanced hypoxaemic states. High-protein diets have been shown to increase serum albumin levels. RGP1 provides a polypeptide marker for Golgi membranes that should be useful in plant membrane studies. Flow cytometric DNA index and karyotype in childhood lymphoblastic leukemia.

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Although risk adjustment is used for all measures, effectiveness varies among measures and methods. A comparison of adherence by four strains of Staphylococcus intermedius and Staphylococcus hominis to canine corneocytes collected from normal dogs and dogs suffering from atopic dermatitis. Semi-quantitative RT-PCR was used to detect the expression of HBV-preS2/S protein. Long-term pulmonary histopathologic changes in rats following acute experimental exposure to chlorine gas. Intraoperative autologous transfusion during elective infrarenal aortic reconstruction: a decision analysis model.

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