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Arapres (Losartan)
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Arapres

Arapres slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes. to treat patients with high blood pressure (hypertension) in adults and in children and adolescents 6 - 18 years of age.

Other names for this medication:
Aratan, Cormac, Corodin, Cosart, Cozzar, Forzaar, Insaar, Lakea, Lepitrin, Lifezar, Loctenk, Lopernal, Losacor, Losapres, Losargamma, Losartan, Losartas, Losartic, Losartil, Losatan, Losatrix, Lostankal, Lostat, Lotar, Lozar, Lyosan, Maxartan, Mozartan, Myotan, Omnitan, Portiron, Rasertan, Repace, Sanipresin, Sarilen, Sedeten, Tacardia, Temisartan, Tozaar

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Also known as: Losartan

Description

Arapres (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Arapres is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Arapres is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Arapres 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Arapres 25 mg, Arapres 50 mg, and Arapres 100 mg may also contain carnauba wax.

Dosage

Take Arapres tablets orally with or without food. Do not crush or chew it. Take Arapres once or twice a day at the same time. If you want to achieve most effective results do not stop taking Arapres suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Arapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Arapres.

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Developments in instrumentation for emission computed tomography. Decision points: the factors influencing the decision to feed in the medicinal leech. Over the past two decades, the incidence of infections due to Candida glabrata, a yeast with intrinsic low susceptibility to azole antifungals, has increased markedly. These results suggest that dexamethasone treatment may have an antiedema effect at an early stage and may modify subsequent development of vascular and inflammatory changes but may have no effect of preventing radiation-induced necrosis and the reduction of N-acetylaspartate after brachytherapy. Comparison of the Heaf (multiple puncture) and Mantoux tests using several tuberculins. We investigated the movement-related cortical fields (MRCFs) recorded by magnetoencephalography (MEG) to identify the motor and sensory brain activities at the instant of the unilateral finger movement using six normal subjects. Functional blocks of the ad-1 and ad-2 mutants of Saccharomyces cerevisiae. Frequency of associated anomalies in congenital hypoplasia of depressor anguli oris muscle: a study of 50 patients. This study tested the hypothesis that chemokine expression patterns were related to upstream cytokine signaling.

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Dynamics of docosahexaenoic acid metabolism in the central nervous system: lack of effect of chronic lithium treatment. Clozapine, but not haloperidol, prevents the functional hyperactivity of N-methyl-D-aspartate receptors in rat cortical neurons induced by subchronic administration of phencyclidine. Gender, age, baseline use of substances, and diagnosis are strong predictors of remission. TLS-CHOP thus leads to the unscheduled expression of a gene that is normally associated with adipocytic differentiation. The patient noted new onset blurry vision and floaters for two weeks prior to presentation. Peripheral cardiovascular actions of SR 58611 A, a beta 3-adrenoceptor agonist, in the dog: lack of central effect. Pancreatic ductal preservation on endoscopic retrograde cholangiopancreatography with CT evidence of a mass should arouse suspicion of an islet cell tumor.

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The palynologically defined Cretaceous-Tertiary boundary in the western interior of North America occurs at the top of an iridium-rich clay layer. Control of glucose metabolism in isolated acini of the lactating mammary gland of the rat. However, there are no previous reports concerning GLP-1-containing neurons in the chick brain. The objective of this study was to review briefly the clinical trials available in the current literature utilizing nonsurgical oncologic treatment (radiotherapy and chemotherapy) either in patients with advanced (i.e., locally inoperable) or metastatic thymoma or as an adjunct to surgery. Improving colorimetric assays through protein enzyme-assisted gold nanoparticle amplification. Although the histological changes in FT related to TCS are well-known, there is no comparative study of the changes which occur in TCS and normal fetal FT samples. They may be employed at different levels of data processing and for quantitative description resp. This is an exciting area of research, and it is anticipated that more findings will emerge in the near future. Cells expressing GM-CSF receptor were Ig positive and both CD5 and CD11 positive (B-1a cell). Is inhibin B a potential marker of gonadotoxicity in prepubertal children treated for cancer?.

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