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Aprical (Nifedipine)

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Aprical is used to treat hypertension (high blood pressure) and angina (chest pain). Aprical is in a class of drugs called calcium channel blockers. Aprical relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
Afeditab, Amarkor, Anpect, Belnif, Bresben, Buconif, Calcibloc, Cardifen, Cardipin, Carditas, Cardules, Casanmil, Cisday, Citilat, Conducil, Coral, Cordilat, Corinfar, Depicor, Emaberin, Fenidina, Glopir, Hexadilat, Lemar, Milfadin, Nifcal, Nifebene, Nifeclair, Nifedel, Nifediac, Nifedigel, Nifedine, Nifedipinum, Nifehexal, Nifelat, Nifezzard, Nifin, Niften, Nipidin, Nirena, Nycopin, Ospocard, Sidalat, Tensomax, Tredalat, Vasdalat, Xepalat, Zenusin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Aprical PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Aprical and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Aprical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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3-Bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin: synthesis and antiviral activity. The A(2)DS(2) score is a valid tool for predicting poststroke pneumonia based on routinely available data. Treatment with corticosteroids usually leads to marked improvement. Comparison of the efficacy and transmissibility of conventional NDV vaccines and vaccines prepared after back-passage through chickens. The behaviour of genetically controlled mutator processes adaptively responsive to stress may reflect such a principle. Here, we report that the screening of a cDNA library with a HLA-A24-restricted melanoma-reactive T cell cloid derived from tumor infiltrating lymphocytes resulted in the isolation of a variant of the gp100 gene that had retained the entire fourth intron of this gene, termed gp100-in4. Both, the diagnostic and therapeutic procedures should adhere to the bio-psycho-social concept of pain. The potential role of methadone-induced cross-tolerance is discussed.

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