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Anxilam (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Anxilam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Anxilam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Aldip, Almac, Alpron, Altin, Alzac, Alzin, Anxiflu, Anxigon, Anxilam, Anxyl, Anzal, Aryalam, Ateez, Axizox, Azolam, Betapax, Calmef, Cooltime, Dazolam, Diprex, Eurolam, Himzolam, Imprax, Indolam, Isorest, Mebasap, Morecalm, Niravam, Parazolam, Plaxid, Plxna, Proprazolam, Rescalm, Setex, Tenzorid, Tranax, Tranisol, Welnorm, Zedel, Zeprax, Zodia, Zoloid, Zolran, Zoltweet

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Colcrys, Minocin, Crestor, Zithromax, Caverta, Zocor, Ticlid, Nolvadex, Flomax

Also known as: Alprazolam


{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Anxilam. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Anxilam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Anxilam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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To measure and compare the optical quality of spherical and aspheric toric intraocular lenses (IOLs). Glomerular localization and transport of aggregated proteins in mice. BV13S1A1-encoded T-cell receptors (TCRs) which bind both monoclonal antibody (mAb) 18B1 and mAb 17D5 are over-represented in the CD4 lymphocyte subset. Process tracking results from the Treatwell 5-a-Day Worksite Study. Dopamine dependent decrease in enkephalin and substance P levels in basal ganglia regions of postmortem parkinsonian brains. Mortality rates increased from 13.5/100,000 in 1953 to 1957 to 17.8/100,000 in 1988 to 1992. The association between the early motor repertoire and language development in term children born after normal pregnancy. Mechanisms of ischemic injury and the central role of vasoconstriction are discussed. 1H NMR spectra of the porcine pancreatic secretory trypsin inhibitor (PSTI) have been recorded vs. Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: effects after controlled ragweed pollen challenge in an environmental exposure unit.

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A laboratory assay to assess avoidance of contaminated sediments by the freshwater oligochaete lumbriculus variegatus. To review the literature concerning the restoration of primary teeth with glass ionomer (GIC) or resin modified glass ionomer cement (RMGI) used in conventional class II cavities. The carapace first appears as the turtle-specific carapacial ridge (CR) on the lateral aspect of the embryonic flank. In a broader context, we will discuss how recent advances in microbiome research may improve and refine current treatment modalities, and the potential of combining them with metabolite-based interventions as a means of achieving a person-specific, integrated and efficient therapy. The average annual individual dose was 1.1 mSv and the maximum annual individual dose was 19.5 mSv. To evaluate conservative management of patients with histological incomplete excision of CIN after large loop excision of transformation zone (LLETZ).

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Improved control of brittle Parkinsonism by separate administration of levodopa and benserazide. We present a novel, automatic algorithm for computing subvoxel precise skeletons of volumetric data based on subvoxel precise distance fields. EDS Type IV has one of the highest mortality rates for pregnant women of any condition with significant morbidity if the mother survives. New work on innate escape behavior shows that mice spontaneously form a spatially precise memory of the location of shelter, which is laid down quickly and updated continuously. From 1993 to 1997, four patients were operated on for ischemic mitral regurgitation secondary to papillary muscle rupture. Four-year trends in the treatment of cerebral aneurysms in Poland in 2009-2012. The subject was debated and reviewed by members of the STS-Congenital Heart Surgery Database Committee and representatives from the European Association for Cardiothoracic Surgery. From an Evidence Based History of Medicine perspective, an accurate and complete examination of all available sources must be carried out to draw a picture of the medical theme examined, and, to reach this aim, the issue of the reliability of sources is a preliminary point to take into account. In general, we can say that the excitability of these cells can be controlled via two distinct mechanisms: 1) the intrinsic membrane properties of the MNCs themselves and 2) synaptic input from circumventricular organs that contain osmosensitive neurons. Head group-functionalized poly(ethyleneglycol)-lipid (PEG-lipid) surface modification for highly selective analyte extractions on capillary-channeled polymer (C-CP) fibers.

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The mitochondrial ADP/ATP carrier: structural, physiological and pathological aspects. Sonographic measurement of soft-palate thickness and comparison with the measurement by computed tomography. Model TRA ECETOC can be easily used to assess inhalation exposure at workplace. Immobilization of coacervate microcapsules in multilayer sodium alginate beads for efficient oral anticancer drug delivery. Effects of chronic intracerebroventricular infusion of neurosecretory protein GL on body mass and food and water intake in chicks. Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis.

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Previous experiments with rifalazil (RLZ) (also known as KRM-1648) in combination with isoniazid (INH) demonstrated its potential for short-course treatment of Mycobacterium tuberculosis infection. Mycoplasma laidlawii B has been studied by phase-contrast and electron microscopy (thin-section and negative staining). Features like dolichocephaly, macrocephaly and ear malformations, associated with duplication of the critical region of Trisomy 5p, are also present, although this region has not been rearranged in our case. This was evident as an early brief increase in the firing rate over the spontaneous discharge followed by secondary inhibition of spontaneous activity. All the rats were administered orally with the glibenclamide (1mgkg(-1)) before the first time and after the last time given HuangKui capsules. Felbamate (FBM) pharmacokinetic parameters, safety and tolerability in the dose range of 1,200-6,000 mg/day were assessed in two open-label studies with similar designs.

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Spectral analysis of low frequency components in the electrical activity of the hippocampus during learning. To evaluate the ability of health-related quality of life (HRQOL) measures to detect change over time in persons with epilepsy. The preservation of biodiversity requires an understanding of the maintenance of its components, including genetic diversity. Drug cost and regulation involves numerous complex issues, a few of which have been addressed here. The electromagnetic field is found to be concentrated on both surfaces of the Ge film at this peak. In corresponding to this result, over-expression of FOXQ1 significantly promoted colorectal cancer growth in vivo. Explicit analytical formulas are derived for the calculation of fundamental third-order aberration coefficients for an arbitrary value of the transverse magnification of the optical system. Importance of molecular size and hydrogen bonding in vasopressin-stimulated urea transport. The addition of FEC-G to the treatment with antibiotics, in febrile neutropenia, decreases duration of days with fever, hospitalization and neutropenia. Effects of tocopherol (vitamin E)-deficient diet on some oral, para-oral, and hematopoietic tissues of the rat.

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We performed a retrospective cohort study based on 61 consecutively identified pediatric TM cases over an -8-year period. Activated T-helper cells formed a major ultram 100 mg tablets portion of the mononuclear cell infiltrate. In psoriasis, double-immunoenzyme staining studies revealed a close spatial relationship between ELAM-1 expression and neutrophil margination, suggesting a functional link. The binding of different Brucella species to B lymphocytes was determined by single- and double-labeling experiments in which a strain of Escherichia coli, coated with anti-light chain antibodies, was used as a marker for B cells. Advanced digestive neuroendocrine tumors: metastatic pattern is an independent factor affecting clinical outcome. This report describes the durability of the edge-to-edge repair without annuloplasty in combination with SVR.

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The aim of this study was to investigate the effects of a simultaneous exposure of BPA, DEHP, and TBT on mesenchymal stem cell differentiation into adipocytes. Aerobic training accelerates Heart Rate Recovery after exercise in healthy subjects and in patients with coronary disease. Yeast is then grown at a high cellular density and high temperatures in large-capacity open tanks with cells recycle. It has been suggested that reduced antenatal care packages or prenatal care managed by providers other than obstetricians for low risk women can be as effective as standard models of antenatal care. Glycosaminoglycan and surface glycoprotein syntheses by rat muscle fibroblast monolayers: response to solubilized bone matrix and effect of serum. Novel SGCE gene mutation in a Korean patient with myoclonus-dystonia with unique phenotype mimicking Moya-Moya disease. Valproic acid: brain and plasma levels of the drug and its metabolites, anticonvulsant effects and gamma-aminobutyric acid (GABA) metabolism in the mouse. Prevention of ischemic stroke and conception of hemodynamic reserve.

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Usefulness of a new model to diagnose alcoholic liver disease in patients with steatohepatitis. The purpose of this report is to evaluate the selective accumulation of polymeric paramagnetic magnetic resonance (MR) contrast agents--gadolinium p-aminobenzyl-diethylenetriaminepentaacetic acid-poly(glutamic acid) (L-PG-DTPA-Gd and D-PG-DTPA-Gd)--in necrotic tissue. Two hundred and ninety-eight patients (151 men, 147 women, aged 17-87 years) on HPN, followed up in 2011 at our Center, were retrospectively recruited. At higher concentrations (heparin/DNA (w/w greater than 0.9) heparin inhibited DNA synthesis in both normal and tumor cell nuclei. Dopamine immunocytochemistry proved to be superior to the other two histochemical techniques in terms of specificity and sensitivity. It was concluded from this result that at least a significant part of the N18 potential was generated caudal to the pontine level or at higher levels via extralemniscal pathways. There is a surge of studies confirming that old age spares the ability to bind in visual working memory (VWM) multiple features within singular object representations. After 24 h of endotoxin administration to adult rabbits, GRP94 mRNA accumulation increases 3-fold in both heart and skeletal muscle and it is followed by a comparable increase in protein accumulation.

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Replacement of RGD by AAA did not abolish rosetting of the corresponding iC3b-coated erythrocytes to human CR3-bearing leukocytes. Weight gain reduction in mice fed Panax ginseng saponin, a pancreatic lipase inhibitor. Furthermore, a significant increase of glioma pathogenesis-related protein was found by RNase protection assay. The CSA of paraspinal muscles in group IB were significantly smaller than those of is zyrtec a 24 hour pill group IA. In tissue culture studies, it has been shown, that fibroblasts and cardiomyocytes form nexus connections. Colon polyps are studied in 400 patients: hyperplastic polyps are found in 107, a combination of hyperplastic polyp with tubular adenoma in 143, tubular adenoma in 72, villous adenoma in 41 and tubulovillous adenoma in 37 cases. We found that the IDL fraction stimulated monocyte chemoattractant protein-1 (MCP-1) mRNA expression in endothelial cells as time- and dose-dependent fashions, while the LDL fraction was not effective. In mice, this hypermetabolism leads to energy deficit and precipitates motor neuron degeneration. Intraventricular haemorrhage in pregnancy due to Moya-moya disease.

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Chromatic aberration correction is achieved by making all the rays travel the same optical distance inside the filter element (negative meniscus). Development of the number of dentists in the Federal Republic of Germany and Berlin (West) to the year 1980. Treatment-related toxicity has correlated with better responses in some cases, and it is probable that serious adverse events from immune-mediated reactions will increase in frequency and severity as immunotherapeutic approaches become more effective. This critical review updates the state of the art on advances in T. We propose and demonstrate a frequency multiplying optoelectronic oscillator with nonlinearly-coupled double loops based on two cascaded Mach-Zehnder modulators, to generate high frequency microwave signals using only low-frequency devices. To confirm the efficacy of ivermectin released from a controlled-release capsule administered to young sheep and to breeding ewes under field conditions. In vivo assessment of skeletal morphology by radiographic densitometry. This case series illustrates the complicated decision-making process of assignment of sex of rearing at birth in 5-alpha reductase type 2 deficiency and the challenges that arise when the interests of the child, parental wishes, recommendations of the medical team, and state law collide.

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In combination with previously reported data on the organization of the midline and intralaminar thalamostriatal projections and the prefrontal corticostriatal projections the present results suggest a high degree of differentiation in the convergence of thalamic and cortical afferent fibres in the striatum. These mice were then given injections of VEGF-neutralizing (mcr84) or control antibodies, and other mice received an adenovirus that expressed mouse VEGF or a control vector. Compared with the control task, discrimination tasks activated the superior and inferior parietal lobules bilaterally, right dorsal premotor cortex, and dorsolateral prefrontal cortex in both genders, consistent with the notion of right hemisphere involvement during exploratory attentional movements. Its mood-enhancing short-term effects may prompt its consumption under stress. administration, we hypothesized that this phenomenon involves the mechanism of action of ZA in bone tissue. This accumulation can only be partially alleviated by modifying the conditions of transcription. Twenty-seven patients with lysinuric protein intolerance, an autosomal recessive disorder of diamino acid transport, have been followed at our hospital since 1965. If the screws can be tightened well, additional dorsal fusion is not necessary. Taking the most important forms of glomerulonephritis--IgA nephropathy, membranous glomerulonephritis and rapidly progressive glomerulonephritis--as examples, the general therapeutic options and a number of specific treatment strategies are discussed. Concomitant with the protective effect of prenatal HI preconditioning, elevation of nitrite/nitrate content in the ipsilateral cortex of the brain, as an indirect measure of NO production, was significantly lower in the PreHI group than in the SH group following neonatal HI.

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A study of periapical overfilling root canal treatment in the molar of the rat. The exercise training has positive impact on autonomic nervous system (ANS) activity. This constitutes a one-step react-and-wash assay which can be performed in a simple channel and does not require flow control elements or moving parts. Most studies were small field tests of protective equipment involving less than 20 workers. A reliable hypoxic nerve injury model has been developed and tested utilizing two functional methods as the primary outcome variables. Natural variation in the genetic architecture of a host-parasite interaction in the bumblebee Bombus terrestris.

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