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Antrolin (Nifedipine)

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Antrolin is used to treat hypertension (high blood pressure) and angina (chest pain). Antrolin is in a class of drugs called calcium channel blockers. Antrolin relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
Adalate, Belnif, Calcigard, Citilat, Conetrin, Coral, Cordalat, Corinfar, Fedip, Ficard, Glopir, Herlat, Milfadin, Nedipin, Nicardia, Nidipine, Nifangin, Nifed, Nifedalat, Nifedate, Nifedical, Nifedip, Nifedipina, Nifedipress, Nifehexal, Nifestad, Nifin, Nirena, Sepamit, Tensomax, Tredalat, Xepalat

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Motilium, Calan, Celexa, Symmetrel, Paxil, Imuran, Floxin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Antrolin PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Antrolin and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Antrolin dosage information

Side effects

The most common side effects associated with Antrolin are:

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Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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These results suggest that during inflammation when both ACh and high levels of fibrinogen are present, NO delivery by erythrocytes might be compromised by their NO scavenging ability that acts as a compensatory mechanism against the overproduced NO by endothelial inducible nitric oxide synthase. The temporal behavior of mode instabilities in active large mode area fibers is experimentally investigated in detail. We used exposure to microwaves from a global system for mobile communication (GSM) mobile phone (915 MHz, specific absorption rate (SAR) 37 mW/kg) and power frequency magnetic field (50 Hz, 15 muT peak value) to investigate the response of lymphocytes from healthy subjects and from persons reporting hypersensitivity to electromagnetic field (EMF). The model applications demonstrated that exemplar-based process models offer a viable account of absolute identification data. Complications of neurosurgery are discussed, notably relapse and depression.

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Histopathological observations and immunohistochemistry staining for IL-17, CD68, and CD34 were performed on 72 specimens (32 cases of LSCC, 20 cases of adjacent tissues of carcinoma as controls, and 20 cases of chronic hypertrophic laryngitis). The different profiles obtained were scanned and analyzed by a computer program in order to determine genetic relationships. Among the Src family members (Src, Fyn, Lck, Yes, and Lyn) present in MDCK cells, Fyn was the only one specifically associated with SHP-2, and the physical interaction between them, which requires the Src family kinase activity, was increased in response to the agonists. The potential efficacy of thalidomide in the treatment of recalcitrant alopecia areata. Firstly, the nature of the SPME fibre was optimised and four different fibres were studied (100 microm polydimethylsiloxane, 85 microm Carboxen/polydimethylsiloxane, 5/30 microm divinylbenzene/Carboxen/polydimethylsiloxane and 85 microm polyacrylate). Specific language growth in young children using the CLARION cochlear implant. The rolling circle replication of small circular plant pathogenic RNAs requires a processing step to convert multimeric intermediates to monomers which are then circularized. Thirty-seven adult patients completed the entry and exit interviews. Research barometer: how is research activity monitored and how is it compared?. Cyclin D1 is required for S phase traversal in bovine tracheal myocytes.

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This reduction was associated with a similar decrease in transcription of PPARgamma mRNA. Information was collected on referral and attendance at adult HIV clinics, eligibility for highly active antiretroviral therapy (HAART) and reasons for lack of attendance. Broken heart syndrome (Takotsubo cardiomyopathy) triggered by acute mania: a review and case report. coli haemolysin, a genomic library was made from an avian pathogenic E. In modern operative restorative dentistry, no restorative material is able to substitute for the human dental enamel in quality, color and resistance. Positive charge on their surface is particularly important for biological and biomedical applications because it strengthens interactions with negatively charged cell membranes. Brain metastasis from follicular thyroid carcinoma: treatment with sorafenib. This study shows that overall the growth of this group of patients with glycogen storage disease type 1 has improved compared to that of a historical control group.

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Effects of alpha-pinene and trichloroethylene on oxidation potentials of methanotrophic bacteria. Mean PTT was significantly shorter than the baseline value 5 hours after administration of a low dose of EACA. The respondent (classical) conditioning of male sexual arousal was investigated, employing penile plethysmography and 2 control procedures. With this information, we were able to generate a PCR system to easily determine zygosity. The effects of folic acid in the prevention of neural tube development defects caused by phenytoin in early chick embryos. Mecamylamine shifted the dose-response curves for nicotine to the right with a gradual depression. Pure and abundant growth of gram-positive bacilli was obtained in culture under anaerobic conditions from the livers of both felines. ATP binding cassette (ABC) proteins of both eukaryotic and prokaryotic origins are implicated in the transport of lipids. Institute of the History of Medicine and Medical Research Tughlaqabad, New Delhi. Research into carbapenems could uncover a new repertoire of bioactive molecules and biosynthetic enzymes, and exploiting these novel enzymes could lead to development of new classes of antibiotics with useful chemotherapeutic activities.

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Overall, surveyed clergy support collaborations to improve childhood mental health. The operationalization of the strategies and rules for forming the concept permitted the construction of the concept of nursing care in hospital settings. Effect of estrogen on the size of low-density lipoprotein particles in postmenopausal women. Bovine beta-lactoglobulin was hydrolyzed with trypsin or chymotrypsin before, during and after treatment at 600 MPa and pH 6.8 for 10 min at 30, 37 and 44 degrees C. The role of DNA methyl transferase I (DNMT1) in allergic inflammation was investigated. However, there have been several reports of patients with mesangial lupus with nephrotic-range proteinuria. Behavior of arterial pressure in progressive muscular exercise 10 watts-minute on the cycloergometer in normal and hypertensive subjects and in coronary disease patients. Unraveling the nature of genetic interactions is crucial to obtaining a more complete picture of complex diseases.

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All the compounds bearing the pyrazole ring close to the BAM moiety show reduced cytotoxicity in comparison to derivatives characterized by the BAM linked to a pyrrole: the same effect has not been observed when occurring at the amidine terminus of the oligopeptidic frame. Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells. Here we report on a case of a 72-year-old male patient with a self-limiting severe acute thrombocytopenia following administration of intravenous non-ionic low-osmolarity contrast medium. The purpose of this study was to investigate the association between SSRI utilization patterns and the use of health care services in the managed care environment. Changes of the lysosome membrane in the early phases of hepatitis caused by MHV-3 virus (mouse hepatitis virus). Economic evaluation is a commonly used tool to compare health-care services and treatments on the basis of costs and benefits. Deletion of either the N-terminal signal peptide or the C-terminal ankyrin repeats abolished RARP-1 secretion by wild-type E.

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Similarly to CO(2) fixation, asparagine synthesized from cyanide is not in an active metabolic pool. Among the 19 patients with splenomegaly, 7 patients were accompanied with calcification. Resource utilization in on- and off-pump coronary artery surgery: factors influencing postoperative length of stay--an experience of 1,746 consecutive patients undergoing fast-track cardiac anesthesia. Molecular cloning of cDNA for lysenin, a novel protein in the earthworm Eisenia foetida that causes contraction of rat vascular smooth muscle. To analyse the value of cardiovascular magnetic resonance (CMR)-derived myocardial parameters to differentiate left ventricular non-compaction cardiomyopathy (LVNC) from other cardiomyopathies and controls. Endothelium-derived relaxing factor as a mediator of bradykinin-induced perinatal pulmonary vasodilatation in fetal sheep. Prevalence and major risk factors of peripartum thromboembolic disease in different regions of Guangdong province.

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Pathogenicity and diagnosis of H5N2 Mexican avian influenza viruses in chickens. All aap fusions were derepressed 3-5-fold after growth on glutamate as a nitrogen source, which effectively causes nitrogen limitation. Experimental coarsening of antiphase domains in a silicate mineral. Treating refractory chronic graft-versus-host disease with extracorporeal photochemotherapy. Thus, while successful and unsuccessful weight regulators seem equally tempted by palatable food, those who are successful in controlling their weight seem better able to resist these temptations by exerting inhibitory control over appetitive responses toward palatable food.

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Activation of muscarinic receptors using the nonselective agonist oxotremorine and a selective M1 receptor agonist also increased extracellular adenosine levels. Study on the method for determination of sulfate in Fe-catalyst by inductively coupled plasma atomic emission spectrometry. Atomic polarizability dominates the electronic properties of peptide bonds upon thioxo or selenoxo substitution. Exact agreement, sensitivity, specificity, positive predictive value, and negative predictive value of the fundus photographs in diagnosing, classifying, and managing cases of suspected exudative AMD were then calculated against gold standard clinical examination and fluorescein angiography. Histopathologic examination showed a well-circumscribed lesion that was consistent with a myxomatous polyp.

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Application of simultaneous determination of inorganic ionic species by advanced ion chromatography for water quality monitoring of river water and wastewater. Lifespan extension by calorie-restriction can also be explained by changes in membrane fatty acid composition which result in membranes more resistant to peroxidation. Despite a gross-total resection followed by a radiation therapy and then a chemotherapy, the death occurred 6 months later. The spotted eagle ray (Aetobatus narinari) is the most abundant inshore elasmobranch in subtropical Bermuda, but its predatory role remains unexamined despite suspected abundance increases and its hypothesized specialization for mollusks. In this paper, biopolymer nanoparticles are studied, which unlike many synthetic carriers used for controlled release, are biocompatible and biodegradable systems. Blood loss into the intestine and into the dialysis equipment was found to be a major cause for anemia of children with chronic renal failure. Although this approach has been useful in modeling severe SMA and very mild SMA, a mouse model of the intermediate form of the disease would provide an additional research tool amenable for drug discovery. Comprehensive peptidomimetic libraries targeting protein-protein interactions. Renal sympathetic denervation was likewise shown to successfully treat hypertension in a previously uncontrolled population. High Hg content in guano and a positive correlation between norvasc brand name Hg and a guano bio-element (phosphorus, P) in the ornithogenic sediment profiles (MB6, BI and CC) indicate that Hg was strongly influenced by guano input.

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Trehalose considerably increased the tolerance of Escherichia coli to air drying, whether added as an excipient prior to drying or accumulated as a compatible solute in response to osmotic stress. The increases in lactate, LDH and M-subunit suggested an anaerobic environment in the cell leading to activation of the anaerobic glycolysis. Use of predictive microbiology in microbial food safety risk assessment. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. The precise identification of the role of amino acid residues in the formation of stable MHC/peptide complexes may be relevant for the design of wild-type-derived epitopes with high immunogenicity. A compartment-based, asymmetric representation of the retina in an induced projection to the olfactory cortex. Indeed, inoculation of newborn mice with plasmids encoding nucleoprotein (NP) or hemagglutinin (HA) of influenza virus, led to the priming of specific cytotoxic (CTL), helper (Th) and B cells, rather than induction of unresponsiveness. SEMS placement should be proposed as the first-line treatment for relief of GOO. Composition of the Milk from Zalophus californianus, the California Sea Lion. The expression of PTTG-1 is independent of the menstrual cycle and is not affected by ovarian hormones.

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The formulation capitalizes on a previously described procedure to obtain how long to wean off lexapro 10 mg stable lipid/DNA complexes for in vitro gene transfer (1). Our results suggest that counting the blood vessels identified by immunohistochemical staining for the endothelial cell-specific CD31 is a powerful predictor for prognosis in patients with metastatic melanoma and should be considered when selecting patients for therapy. MRS data revealed an increased choline to creatine (cho/cr) ratio and a decreased N-acetyl-aspartate to creatine (NAA/cr) ratio, which demonstrated a return to near normal ratios on follow-up study. CT findings in patients with familial Mediterranean fever during an acute abdominal attack. The viscous secretion is stored at the top of each seta and absorbs water from moist air. Excitability of motor cortex inhibitory circuits in Tourette syndrome before and after single dose nicotine.

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Infective endocarditis following orthotopic heart transplantation: 10 cases and a review of the literature. Acute tissue injury is often considered in the context of a wound. RP-HPLC shows that ansocalcin is the major component in extracts of goose eggshells before and after bleach treatment. Gluconeogenesis and HGP were inhibited by sitagliptin in high fat-induced obese rats due to decreased glycerol availability, which was a result of reduced glycerol release from adipose tissues. The constraint created by dissolution of CO2 at cell surfaces substantially decreased the CO2 flux and its concentration inside chloroplasts, especially at high temperatures.

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Infrared spectroscopy and site-directed labeling experiments using pyrene ruled out structural reorganizations within the discrete oligomers. The case of a 34 years old patient, with an adrenal pheochromocytoma and a Cushing syndrome is reported. The prevalence of self-reported musculoskeletal pain/discomfort and visual strain symptoms was high among data processors. Moreover, gastrokine-1 expression levels tended to be associated with the severity of chronic gastritis. The aim of this study was to examine the outcome of a population of Asian patients with advanced ethmoid sinus cancers that had been treated with surgery plus combined therapy.

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Signet-ring sinus histiocytosis is a rare and distinctive reactive disorder found incidentally in the pelvic and axillary lymph nodes of patients with carcinoma of the prostate and breast, respectively. Performance on cognitive tasks in predicting the behavioral competences in the institutionalized elderly. However, primary mammalian cell types (dissociated cells or acute tissue samples) are often difficult to maintain undifferentiated in culture and the current established methods of introducing molecular reporters in single cells are laborious (micro-injection) and/or require cell culture techniques to accommodate the 1-2 day lag time of genetically mediated reporter expression. Primary cultures of human renal proximal tubular epithelial cells were co-incubated with angiotensin II alone or in combination with the angiotensin II AT1 receptor antagonist losartan or/and the AT2 antagonist PD123319. Multiple cerebral arteriovenous malformations (AVMs) associated with spinal AVM. Evolution of blood serum globulins as determined by pregnancy in the domestic donkey (Equus asinus L.). furiosus NROR (PF1197) was found to be exceedingly toxic to Escherichia coli, and an active recombinant form (rNROR) was obtained via a fusion protein expression system, which produced an inactive form of flagyl 500 mg prix NROR until cleavage. Here, a modified strategy for obtaining sequence specific assignments based on two dimensional amino acid type selective triple-resonance experiments is proposed.

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Cord blood-hematopoietic stem cell expansion in 3D fibrin scaffolds with stromal support. The c-kit gene obtained from FMA3 cells was found to have 21-base deletion at the juxtamembrane domain of KIT, thereby leading to the constitutive activation of KIT. Analysis of cell viability using time-dependent increase in fluorescence intensity. The active ingredient pancreatin induced hydrolysis of the ester based film-former hydroxypropyl methylcellulose acetate succinate (HPMCAS). coli Rth is indeed responsible for the maintenance of cell wall rigidity.

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The recently introduced x4 3-dimensional (3D) ultrasound probe allows both real time 3D imaging and gated acquisition sequences. The effect of paired electrical stimulation of the heart on its hemodynamics. Clinical, radiologic, and histopathologic features and possible pathogenesis are discussed. Mitotic activity of the lenticular epithelium and mechanical action of the zonular fibers. Numerous proteins presumed protonix dosage po to be chromatin associated were identified and their chromatin interactions were explored. Treatment of hepatic coma by purification in a heterologous liver. On-line liquid chromatography-accurate radioisotope counting coupled with a radioactivity detector and mass spectrometer for metabolite identification in drug discovery and development.

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