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Antidep (Imipramine)

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Antidep works by inhibiting the reuptake of certain neurotransmitters in the brain, including acetylcholine, dopamine, norepinephrine, and serotonin. It also acts on certain other receptors, such as H1 receptors for histamine. Antidep usually is administered orally but may be given by intramuscular injection.

Other names for this medication:
Alzoset, Anxitab, Anxofit, Depforte, Depof, Depranil, Depsan, Depsin, Depsodep, Depsolam, Depsonil, Elidep, Estidep, Imidiaz, Imipra, Imodep, Impramine, Impranit, Imprax, Karthin, Lastinem, Libomin, Microdep, Nimipose, Normadep, Prazep, Trydep

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Tricor, Rocaltrol, Zyprexa, Risperdal, Flomax, Minipress, Prograf

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Also known as: Imipramine


Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain imipramine. It may not be specific to Antidep-PM. Please read with care.

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules): For depression: Adults—At first, 75 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day, unless you are in the hospital. Some hospitalized patients may need higher doses. Teenagers and older adults—At first, 25 to 50 mg per day using the tablets. Your doctor may adjust your dose as needed and switch you to the capsule form. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): For depression: Adults—At first, 75 milligrams (mg) per day. Your doctor may adjust your dose as needed. However the dose is usually not more than 200 mg per day. Some hospitalized patients may need higher doses. Teenagers and older adults—30 to 40 mg per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For enuresis (bedwetting): Children 6 years of age and older—At first, 25 milligrams (mg) once a day, taken 1 hour before bedtime. Your doctor may adjust the dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Antidep can be fatal.

Overdose symptoms may include irregular heartbeats, feeling like you might pass out, seizures, or coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Antidep-PM dosage information

Side effects

The most common side effects associated with Antidep are:

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Pyroglutamic acid in cheese: presence, origin, and correlation with ripening time of Grana Padano cheese. Mutation analysis for TGFbetaRII, IGFIIR, and BAX was performed in cancers with MSI. The two groups of subjects did not significantly differ in the number of cells bearing typical natural killer (NK) markers (both in resting and MP stimulated PBMC) and NK activity. Two NIH-funded initiatives are developing assessment tools, in English and Spanish, which address these issues, and should prove useful to the study and treatment of epilepsy and other neurological conditions. Furthermore, this induction was independent of an alteration of ECE-1 gene levels, suggesting that these two genes have a different pattern of regulation by the same stimuli in this cell type. In the work described here, we examined the components of the IFN-gamma signal transduction pathway in RAW 264.7 and WEHI-3 cells to determine whether differences in pathway components or activity exist in WEHI-3 cells that could give rise to this difference in transcriptional response. Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation. Continuous passive motion following total knee arthroplasty in people with arthritis. Furthermore, anti-chitinase 3-like-1 antibody-treated mice exhibited a significantly lower load of Salmonella typhimurium in peripheral organs as compared to control rabbit IgG-treated mice. Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin.

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Serum alkaline phosphatase and zinc undernutrition in infants with chronic diarrhea. These results suggest that PEI-LP can deliver DNA to the mitochondrial sites and may be useful for the development of mitochondrial gene therapy. Prophylactic Bracing Has No Effect on Lower Extremity Alignment or Functional Performance. To describe the anthropometric, metabolic and reproductive parameters of patients with CPP due to HH before and after treatment with gonadotropin-releasing hormone analog (GnRHa). Phrenic nerve conduction study in demyelinating neuropathies and open-heart surgery. Although this series of events appears to be highly conserved among eukaryotes, its mechanistic function in transcription is unknown. Although distribution volume and clearance display age-dependent maturation, it is important to recognize that important, unexplained interindividual variability in drug metabolism is still observed. An epidermal cytoplasmic staining pattern was also detected, which was most pronounced using the anti-rIL-6 antiserum. We compared three models to describe gene regulation of the flowering transition process in Arabidopsis.

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In almost all cases of liver cirrhosis (LC) and hepatocellular carcinoma (HCC), serum integrin levels were significantly elevated, but were in the normal range in gastric, colon, lung cancer, and acute hepatitis (AH). The abundance of citrate synthase corresponded with rates of metabolism of Geobacter bemidjiensis in chemostat cultures. Psychosocial and behavioral interventions for young adult cancer patients and survivors often involve assisting these individuals in retaining or returning to function in significant social roles, such as spouse, parent, student, worker, or friend. Elisapterosin B displays strong in vitro anti-tuberculosis activity. Concomitant detection of those markers can be used in differential diagnosis of parenchymatous jaundice and mechanical jaundice of tumorous etiology. The objective of this study was to determine which isoform of cytochrome P450 enzyme is responsible for the majority of vinblastine metabolism in dogs. Exposure to 4 courses of betamethasone is associated with increased placental capillary density. Chronic disease burden associated with overweight and obesity in Ireland: the effects of a small BMI reduction at population level. Intravenous immunoglobulin in combination with other prophylactic and therapeutic measures.

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All these methods are MS based and able to provide a whole picture of glycosylation of a glycoprotein. In adulthood, OUT males showed increased general and central locomotion activity in the open-field test, reduced sexual behavior, and attenuated prolactin secretion in response to restraint stress compared with the IN littermates. Time-course studies of immediate and delayed immune reactivity in patients with atopic dermatitis treated with herbal drugs. To investigate the use of indocyanine green (ICG) lymphography in the diagnosis and assessment of the severity of lymphatic dysfunction in infants and neonates with congenital lymphatic pleural effusion and ascites. The current screening protocol involves an annual colonoscopy and biopsy after the patient has had the phenergan dose children disease for 8 years. After phosphorylation of the immobilized peptides, phosphorylation was detected by fluorescence imaging. Ins and outs of dietary phytochemicals in cancer chemoprevention. These shape components are independent of size, suggesting that male mating success is a complex function of size and shape. Short-term studies support the efficacy of less invasive treatments, which are associated with less periprocedural disability and pain.

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Approximately 474 patients younger than 18 years who received a first CI from 1999 to 2011. Cancer information and support needs of statutory and voluntary sector staff working with people from ethnically diverse communities. The product of the linA gene was 16.5 kDa according to sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The product primary alcohol was detected in a cell-free system but only in a trace amount in the whole cell system due to further oxidation. Localized lesions of the medial and lateral frontal cortex were used to study gliosis, neurofilament content and changes in synaptic density in the mouse striatum. These abnormalities may explain the poor outcome of epilepsy surgery in patients with this form of dysgenesis. Self-esteem modulates the latency of P2 component in implicit self-relevant processing. We discuss the clinical findings, therapy and outcome of a series of forty patients we have seen in our hospital from 1979-1991.

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Zeaxanthin-producing colonies grew about twice as fast as lycopene-producing colonies throughout a time course of 11 days. Thereby force measurement method could be simplified and applied to large-scale experiment on chip. RTStar also automatically warns the planner when a collision would occur during patient set-up. The interferon-inducing activity of new derivatives of gossypol, a low molecular weight natural polyphenol, and its model compounds was studied in regard to their chemical structure. Understanding the pathogenesis of this neurologic disease and the kinetics of HIV replication in brain tissue of children with AIDS encephalopathy is essential to determine the best therapeutic strategy.

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FREQUENCY-DEPENDENT SELECTION AT vantin with penicillin allergy THE PAYNE INVERSION IN DROSOPHILA MELANOGASTER. Early career location of University of Adelaide rural cohort medical students. In the current studies we sought to determine whether TNF-alpha, IL-1beta, the complement system and oxidants contribute to the activation of NF-kappaB in the lung. Minimum tillage reduces the number of trips over a field, lessening soil compaction and reducing costs. The perturbation of GEM impairs tyrosine phosphorylation and, consequently, mitogenic signaling of the TCR. In most patients cotrimoxazole preventive therapy was consistent with the national guideline regarding the rationale for indication, dose, discontinuation and its use in the presence of contraindications. Keratotic skin lesions and other risk factors are associated with skin cancer in organ-transplant recipients: a case-control study in The Netherlands, United Kingdom, Germany, France, and Italy.

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The serum sodium concentration reflects the osmolality of the extracellular fluid and provides no direct information about total body sodium content. It also concludes that cows may be able to adapt to high nitrogen diets so that diets that may reduce their fertility when introduced at critical periods, for example, when they are inseminated, do not reduce it when introduced at paxil medication wikipedia an earlier stage. The influenza A virus M1 protein interacts with the cellular receptor of activated C kinase (RACK) 1 and can be phosphorylated by protein kinase C. Thus, exploring the mechanisms of virus transmission from macrophages to target cells such as other macrophages or T lymphocytes is central to our understanding of HIV-1 pathogenesis and progression to AIDS, and is vital to the development of vaccines and novel antiretroviral therapies. However, despite concerted efforts in the field, progress in the use of RNAi technologies in zebrafish has been extremely slow and a reliable means of RNAi-mediated gene knockdown remains elusive. Thus, age-related changes in proteoglycan distribution exist and correlate with morphologic and functional changes that occur in the intrinsic process of aging in human skin. Microfilamentous type VI collagen in the hyalinized stroma of the hypertrophied ligamentum flavum.

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Then a five-second VAS was given and FM and (or) FHR was observed. An array of clinical issues remains to be resolved for castration-resistant prostate cancer (CRPC), including the sequence of drug use and drug cross-resistance. Clinical risk factor assessment, with or without BMD measurement, is a reliable predictor of 10-year risk of osteoporotic fracture and may be particularly useful in regions or primary care clinics without access to bone densitometry equipment. Binding of phenazinium dye safranin T to polyriboadenylic acid: spectroscopic and thermodynamic study. OSA patients experience repetitive brief cessation of breathing throughout the night, which causes intermittent hypoxemia (reductions in hemoglobin oxygen levels) and fragmented sleep patterns. Neurovisual rehabilitation: recent developments and future directions. These findings raise concern about a reversal of the observed improvement in prostate cancer specific mortality during preceding decades. These findings should be taken into consideration when deciding on the treatment strategy for elderly ACS patients undergoing PCI. Despite combined-modality treatment the disease progressed and the patient was operated on for third time 2.5 years after the first operation with partial tumor resection.

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After the intraperitoneal application of 3H-proline a higher grain density over the myocardium and the aorta in comparison with the cartilage, the glomeruli and the cutaneous connective tissue of rats was found. In fluid phase dimyristoylphosphatidylcholine, the rotational motion of the residues decreased slightly with increased packing, but in the gel phase a significant reversible increase was observed. A New HIV Paradigm: Dual Antiretroviral Regimens as Maintenance Therapy. Acute postoperatory visual loss following bilateral lung transplantation surgery: a case series. Clonality: an R package for testing clonal relatedness of two tumors from the same patient based on their genomic profiles. The frequency of signs and symptoms associated with OC may explain some of the clinical manifestations.

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