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Amitone (Amitriptyline)

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Amitone is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

Other names for this medication:
Abamax, Amimax, Amitar, Amitin, Amitrac, Amitrim, Amitrix, Amitrol, Amitryptyline, Amity, Amiwel, Amixide, Amline, Amsha, Aptric, Arpidox, Axtrip, Bluneel, Chlotrip, Eliwel, Endep, Estiline, Latilin, Latiln, Libral, Lodep, Maxitrip, Raitrip, Relidep, Tablin, Tadamit, Teedep, Tridep, Triplent, Trixide, Tryline, Vanatrip

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Also known as: Amitriptyline


{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitone dosage information


If you overdose Amitone and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitone overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline.

Avoid driving or hazardous activity until you know how Amitone will affect you. Your reactions could be impaired.

Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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We identified gender related differences of inducible nitric oxide synthase (iNOS) expression and NO production in mice with experimental autoimmune encephalomyelitis (EAE). Reutilization of paraformaldehyde tablets: assessment of their sterilizing effect. A better understanding of this involvement could lead to the development of new and improved treatment strategies. The experimental rat brain was perfusion-fixed at 1, 6 and 24 hours after traumatic brain injury. In addition to pure-tone and speech reception thresholds, perception of spectrally or temporally distorted speech as well as auditory resolution of frequency, time, and space were tested. Does sulphasalazine cause drug induced systemic lupus erythematosus?.

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The framework presented here provides an ideal setting for modeling mutations dispersed through the genome and, in particular, for the analysis of how natural selection operates on different classes of single nucleotide polymorphisms (SNPs). We present our experience using this device in older subjects referred to a dedicated falls and syncope clinic in whom usual clinical assessment had not satisfactorily identified an attributable diagnosis but where we still suspected a cardiovascular cause for syncope or falls. An expanded factor analysis model (ME-2) that is capable of taking into account the influence of independent variables such as wind speed, wind direction, time of year and other variables of the measured fine particle matter (PM2.5) concentration data was utilized for identifying sources of airborne pollutants and providing quantitative estimations of the contribution of each source. The pituitary glands of eight normal ewes at various stages of the oestrous cycle and three rams were compared with those of two male-type and three undifferentiated-type freemartins. Abnormalities of viral internalization may be one mechanism accounting for this difference. No differences were found between the five groups, either in the average levels of the trace elements or in the correlation structures between the trace elements. Patients with squamous cell carcinoma of the head and neck (SCCHN) who receive radiotherapy in combination with epidermal growth factor receptor (EGFR) inhibitors, such as cetuximab, may develop a characteristic acne-like rash in addition to dermatitis. Applying results from selected series to elderly patients with acute leukaemia is inappropriate. In Russia, where health status has deteriorated since the late 1960s, asthma is a growing medical and public health problem. Place of residence may have a greater effect on disability than race.

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Fluorescein angiography in retinal arterial branch obstructions. Muscular and neurologic function in patients with recurrent dislocation after total hip arthroplasty: a matched controlled study of 65 patients using dual-energy X-ray absorptiometry and postural stability tests. Sirolimus-eluting stent treatment for isolated proximal left anterior descending artery stenoses. Multigene families encode enzymes of the hydrogenosome organelles, which have identity to adhesins. The most promising treatment results have thus by far been achieved through a combination of cognitive behaviour therapy and supportive cooperation between parents, the school, and the treating child psychiatrist, occasionally supplemented with pharmacological treatments such as selective serotonin reuptake inhibitors. Chlamydia pneumoniae infection in adult patients with persistent cough. This study investigated solutions that permit reasonable determination of elastic properties in the human mandible. The authors hypothesized that perioperative in vitro platelet responses to varying agonists (eg, thrombin, platelet activating factor, collagen, adenosine diphosphate) correlate with early graft thrombosis after off-pump coronary artery bypass grafting (OPCAB).

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Factors which may have contributed to gastric carcinogenesis in this patient are discussed. Leukodystrophy associated with oligodontia in a large inbred family: fortuitous association or new entity?. This part also shows simple surgical measures in order to stop bleeding. BRL 13776: a novel antihypertensive agent with interesting monoamine depleting properties. On the left side, she received carpal tunnel release via open method in our clinic, and has not suffered from recurrence in eight years. We describe our experience with refluxing ureteral reimplantation as a novel method for temporizing the obstructive megaureter. If the disparity in service provision described is to be altered then the planning and development of health services should concentrate upon the provision of basic health care and adapt to the manpower and economic constraints within zyrtec generic rx which such systems operate. Mass spectrometry and ferric chloride oxidation applied to urobilinoid structures. They were concerned about the complexity of genetic testing, the lack of evidence regarding management, and the implications for families.

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