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Alrif (Alprazolam)

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Alrif is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alrif is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alrif may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aldip, Alpam, Alpaz, Alpra, Alpraday, Alpraquil, Alprastan, Alprogard, Alzam, Alzex, Alzonex, Anilam, Anlzium, Depflu, Depsolam, Dizeral, Elzopam, Emcalm, Esteem, Fluprax, Fluzolam, Meloprax, Normatine, Procalm, Prozam, Selamb, Somaspas, Sozox, Tensfree, Tenzorid, Trika, Viprax, Xycalm, Zepro

Similar Products:
Paxil, Crestor, Starlix, Actos, Detrol, Temovate

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alrif dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alrif are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Alrif if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Alrif is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Alrif while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Alrif is not approved for use by anyone younger than 18 years old.

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SV40-transformed mKSA cells (H-2d) readily induce progressively growing tumors in adult syngeneic BALB/c mice while expressing the full complement of H-2d MHC class I antigens. Our results suggest that the ovarian hormonal, cholinergic, and serotoninergic systems play a role in age-related cognitive disturbances under conditions of hypoestrogenic syndrome. Measuring underreporting and under-ascertainment in infectious disease datasets: a comparison of methods. Drop drying and deposition phenomena reveal a rich interplay of fundamental science and engineering, give rise to fascinating everyday effects (coffee rings), and influence technologies ranging from printing to genotyping. With good clinical efficacy, short menstrual bleeding time, as well as the same appearance and insertion technic as stainless steel ring, the MSSR-165 will be easily accepted at the grass root level. In contrast, the extent of bone ingrowth on the femoral side was maximal at 12 weeks. Although the pressure to limit life support may be appropriate in some circumstances, in others it is not justified. Natural antioxidants plays a vital role in enhancing the stability and quality of meat.

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To understand the role of cell shape changes on matrix metalloproteinase expression in human glioma cells, we treated SNB19 cells with cytochalasin-D, an inhibitor of actin polymerization, and colchicine-B, a tubulin inhibitor, in the presence of phorbol 12-myristate 13-acetate. Grafts implanted into ibotenic acid-lesioned striatum grew rapidly (about five-fold) in volume over the first week. Understanding it may facilitate development of food appropriate for individuals with dysphagia. Radiological features evaluated using magnetic resonance imaging (MRI) were the segmental level of the pathology, the location and morphological features of the disc herniation, the cross-sectional area of the disc herniation and its ratio to the cross-sectional area of the spinal canal, and the grade of nerve root compression. The left LDM was detached from the thoracic wall, divided longitudinally and reattached in situ to achieve vascular delay. T-wave alternans (TWA) is a promising electrocardiogram (ECG) predictor of sudden cardiac arrest, yet needs specialized recordings for conventional spectral analysis. Furthermore, we aimed to address the usually critically eyed point, whether it is possible in a parallel screening system to differentiate between similar molecules/molecules acting on closely related proteins, and therefore we incorporated a collection of other protease inhibitors including aspartic protease inhibitors. The formation of double-stranded helices is induced by adenine protonation.

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All patients were stratified, according to the NCCN classification, in low, intermediate and high risk, and all of them showed histologically proven adenocarcinoma stage T1-T3 with at least 2 years of follow-up. Full dose treatment protocol (prednisolone 1 mg/kg for 5 days then fluticasone spray 250 mg four puffs daily plus salmeterol spray 25 mg four puffs daily), which was routinely used for severe asthma, was administrated and patients were followed up for 2 months. Coronary artery dysfunction seen in other studies after less ischemia may be the result of injury introduced during reperfusion, may be the consequence of myocardial injury, or may be due to events operative at the level of small arterioles. A peripheral membrane protease was purified from mitochondria of rat submaxillary gland. To understand the relationship between activation and/or inhibition of these pathways and regulation of gene expression controlled by specific response elements, cell lines were prepared containing the TPA response element (TRE), serum response element (SRE), or cyclic AMP response element (CRE) fused to a gene encoding a secretable form of alkaline phosphatase (SEAP). Strikingly, scientific information is scarce, with most studies coming from only one country (Brazil). In a group of long-standing diabetics low shear blood viscosity was increased compared with matched non-diabetic controls, being highest in patients with vascular and microvascular complications. Thus the effect on ageing changes of the tissue of origin may also be studied. Teaching and training laboratory professionals for the 21st century.

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Fascioliasis is a great tropical disease all over the world so we tried to investigate the incidence of fascioliasis in the Antalya region of Turkey and also to find an answer to the question if initial ultrasonographic examination (US) and eosinophil count is a predictive sign in diagnosis of fascioliasis. The etiologic significance of different adenovirus serotypes in various clinical forms of respiratory tract diseases. Epithelial remnants and pearls in the secondary palate in the human abortus: a contribution to the study of the mechanism of cleft palate formation. Chlorophyll and carotenoid patterns in olive fruits, Olea europaea Cv. Detection of RASSF2 and sFRP1 promoter region methylation in sporadic colorectal cancer patients. During the study period, 2994 patients with bronchogenic carcinoma underwent surgery. Polyinosinic-polycytidilic acid (poly IC) is a synthetic double-stranded RNA (dsRNA) and mimics viral infection when applied to cell cultures. Diets with conventional amounts of protein, as well as high-protein diets, are reviewed.

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S lugdunensis is more virulent than other coagulase-negative staphylococci and in many clinical situations behaves like S aureus, further increasing the confusion. In this study, we assessed anterior segment parameters of the healthy rabbit eyes with Pentacam HR (Oculus, Wetzlar, Germany). The genes for GnRH, LH beta, and FSH beta are present in patients with IHH. Both hypoxia and acidosis affect the tissue redox status and its key intracellular component, glutathione (GSH). Several compounds have been tested for stent coating, primarily with the aim of the inhibition of SMC proliferation. The result showed that the immune response of TT increased when it was combined with DT in liposomes. To cut costs of screening peptides for a new serological assay, the concept was investigated of using cheap non-purified (crude) peptides instead of purified peptides. Following bolus intracameral injection at the end of cataract surgery the concentration of vancomycin in the anterior chamber vastly exceeds its MIC for at least 24 hours but is predicted to fall below the MIC after 33 hours.

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Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. This review will focus on signaling by type I cytokines and in particular on signaling by the IL-2 family of cytokines, as an illustrative example. Comparison of cortical responses to stimulation of thalamus and fornix. Digital cytology: current state of the art and prospects for the future. In this report, we have compared and contrasted the effects of these new agents in Taxol-sensitive and -resistant cell lines. However, doubts about the generalisability of the studies, the poorly defined nature of the interventions tested, and the lack of studies including cost assessments and patient outcome data indicate that more rigorous research is needed to document the effects of outpatient pharmacist interventions. The specificity was investigated using hepatocytes from humans as well as rabbit, rat, guinea pig and monkey. These results show that hypoxia can produce abnormalities of hypothalamic-pituitary function and that these are primarily located in the hypothalamic-pituitary-testicular axis. Efficiency of traps for Stomoxys calcitrans and Stomoxys niger niger on Reunion Island.

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FDPOs enhanced wound healing in db/db mice as well as FDPIs and RT-PLTs. Axonal and glial pTrkB-ir and pTrkB-ir in the CA1 stratum radiatum were more abundant in high-estradiol states (proestrus females) than low-estradiol states (estrus and diestrus females and males). Functional near infra-red spectroscopy (fNIRS) in schizophrenia: A review. Sixty-eight did not have carcinoma of the prostate (CAP), 28 had CAP less than 1 ml and 9 had CAP larger than 1 ml. A cloning and expression analysis of pregnancy-associated glycoproteins expressed in trophoblasts of the white-tail deer placenta. The electroencephalogram (EEG) and visual evoked potential (VEP) in association with catecholamine contents and myelin basic protein (MBP) immunoreactivity were carried out from the 1st to the 20th day of postnatal age. Scaly scalp is a common problem in the pediatric and adolescent population.

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To describe a case of diabetes mellitus in a koala (Phascolarctos cinereus). Hemopneumothorax is very rarely seen as the pulmonary manifestations of rheumatoid disease. Interestingly, the serum-resistant pulmonary strains were isolated from animals with systemic lesions. Central neurocytomas occur in young adults, develop in the area of the foramen of Monro, and are usually associated with the septum pellucidum. Adhesion formation can be reduced by the suppression of transforming growth factor-beta1 activity. Such knowledge is being quickly translated into the identification of etiologies and improved prophylaxis and therapy of disease. That beta 1 integrin expression was involved in SCLC adhesion was suggested by the adherence of H345 cells to laminin, a known ligand for the alpha 3 beta 1 integrin.

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Acetylsalicylic acid in critically ill patients: a cross-sectional and a randomized trial. In a high-capacity calf-house, twenty-one calves were subjected to repeated clinical and biochemical examination until they were 22 weeks old. The evidence supporting the relationship between breakfast consumption and body weight is growing, but the mechanisms to explain this relationship are less understood. Rationale and rational tumor after-care from the viewpoint of a community hospital. The molecular weight of the cytoplasmic aldehyde dehydrogenase was determined to be 230,000 daltons, larger than the mitochondrial enzyme by approximately 15,000 daltons. CP (with metabolic activation) and EMS significantly increased the SCE frequencies. Forest had higher turnover rates than the other two habitats for all bird species.

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Selected most potent polymers from the initial screen were tested for toxicity in A549 human lung cancer cells, and in vivo in a systemic gene delivery model in mice employing a firefly luciferase expressing plasmid. Adaptation and antibiotic tolerance of anaerobic Burkholderia pseudomallei. Letter to the editor: Response to intubation and salicylate overdose. Clinical experience in re-evaluation of the therapeutic role of chlorpromazine. Correlations between electrophysiological activity from the human olfactory bulb and the subjective response to odoriferous stimuli. To test whether genetic instability may determine whether tumours become aneuploid or diploid. VEMP from the ear with the larger amplitude were evaluated based on the assumption that the majority of the tested patients probably had normal vestibular function in that ear. An administrative claims model for profiling hospital 30-day mortality rates trazodone 50 mg tablet picture for pneumonia patients.

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Clinical efficacy of a stable prostacyclin analog, iloprost, in diabetic neuropathy. This model has to be suitable for computer simulation, while preserving as accurately as possible important anatomic features. To evaluate the frequency and phenotypes of Treg cells in blood of patients with PV. Outcomes in ASE and ARE peritonitis were similar, but vancomycin was required during treatment for ARE peritonitis, in turn possibly predisposing the patients to infections caused by vancomycin-resistant organisms. These results indicate an unexpected role of P2RY2 in the carcinogenesis of human cancers. Selective interference with viral RNA formation in vitro by specific inhibition with synthetic polyribonucleotides. By usage of computer controlled spatial light modulators, we are able to implement fully randomized nondiffracting beams of variable structural size in order to control the modulation length (photonic grain size) as well as the depth (disorder strength) of a random potential induced in a photorefractive crystal. Influencing agricultural policy: a call for intersectoral collaboration to reduce obesity and climate change. Our experience suggests that it is practical to expand the scope of access to include these patients.

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Differences between physical examination findings of cattle with concurrent disease and those of cattle with uncomplicated displacements were evaluated, as were differences between survival rates in cattle with focal versus diffuse peritonitis. ECOTYPIC DIVERGENCE IN ALPINE POLEMONIUM VISCOSUM: GENETIC STRUCTURE, QUANTITATIVE VARIATION, AND LOCAL ADAPTATION. To investigate prolactin (PRL) and thyrotropin-stimulating hormone (TSH) secretion in ovarian failure, 14 women with primary ovarian failure were challenged with luteinizing hormone-releasing hormone (LHRH) (100 micrograms) and thyrotropin-releasing hormone (TRH) (200 micrograms) given intravenously at 30-minute intervals. Effect of phenyramidol and bishydroxycoumarin on the metabolism of tolbutamide in human subjects. Immune Correlates of GM-CSF and Melanoma Peptide Vaccination in a Randomized Trial for the Adjuvant Therapy of Resected High-Risk Melanoma (E4697). We emphasize the difficulties in estimating the prognosis in cancer diovan hct generic cost patients after cardiopulmonary resuscitation and discuss the mentioned study by Champigneulle et al., which results might by influenced by selection bias. The amperometric response of glucose with the biosensor under optimal conditions exhibited a linear relationship in the range of 5.0 x 10(-5) to 3.0 x 10(-3) M with correlation coefficient 0.9995. The effects of early-life undernutrition and subsequent environment on morphological parameters of the rat brain. Attention-deficit/hyperactivity disorder: a neuropsychiatric disorder with childhood onset.

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Our findings show an autonomic dysfunction in patients with OSAS. Partial purification of pulmonary cytochrome P-448 from 3-methylcholanthrene-treated rats. H33342 enters cells and targets DNA at adenine-thymine-rich regions of the minor groove. Defining the relationship between gastroesophageal reflux and cough: probabilities, possibilities and limitations. We estimated 1-year savings if patients identified during screening in a dental setting were referred to a physician, completed their referral, and started pharmacological treatment. The optimum pH ranges were determined to maintain stability of the tresyl chloride modified star reagents, and the chemistry was designed for their subsequent linkage to the immunoadsorbent moiety. The method of determination of true density affects the results dramatically as does the accuracy of the powder height determination. Purification of an ascomycin derivative with simulated moving bed chromatography. Adequately controlled trials of routine ultrasound imaging in early pregnancy.

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Intensive coronary care units in community hospitals: a pilot project. Despite their well-established advantages, bilateral internal thoracic arteries (BITA) are still largely underused. Our observations of the zantac 75 mg side effects cotransport of multiple SCb proteins in single axons suggest that they move as multiprotein complexes. The study failed to find significant differences in either self-esteem or body image between the two groups. Conclusions will be drawn as to how the overall value of cleft lip surgery may be enhanced. Tenocytes intrinsic to rat Achilles tendon were treated with low-level laser (660 nm).

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Phase II study of YM881 (zinostatin stimalamer) suspension injected into the hepatic artery. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease of right ventricular morphology, as well as in a rodent model of right ventricular hypertrophy (RVH).MethodsHomogenates of right ventricle (RV) explants from non-failing controls and children born with a SV were assayed for HDAC catalytic activity and HDAC isoform expression. OKY-046 decreased TBX2 to undetectable values, increased 6-keto-PGF1 alpha by 8-fold, and significantly reduced both systolic and diastolic blood pressures in hypertensive patients. The more extensive the solid portions of the lesion, the higher the probability of malignancy and the poorer the prognosis. Computer-controlled dynamic treatment, radioprotector drugs, hyperbaric oxygen, carbogen breathing during irradiation, particle irradiation, and hypoxic cell sensitizing drugs are presently undergoing clinical evaluation with some encouraging preliminary results. Comment to: gastric carcinomas with unusual cytoplasmic ultrastructural features. Preventing activation of ERK1/2 reduced the ability of rapamycin to inhibit TNF-induced VCAM-1 expression.

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The reduction of FHIT protein expression may play an important role in the development ticlopidine drug class of rectal carcinoma, and FHIT protein may be associated with the regulation of cell apoptosis. The basic objectives for rehabilitation are defined: to improve exercise efficiency, aerobic capacity and quality of life, to reduce the incidence of sudden death, to enable young patients to take part safely and effectively in athletics. Impaired force coordination during object release in children with hemiplegic cerebral palsy. This article presents a patient with unilateral scissor bite in mixed dentition with alveolar narrowing. Potentiation of acid-sensing ion channels by sulfhydryl compounds.

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