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Alprotame (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprotame, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprotame is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Acalm, Alpanol, Alpose, Alpron, Altin, Altrex, Alzam, Alzotime, Ambutech, Anxizam, Azicalm, Azolam, Coolam, Depflu, Depoxit, Depsolam, Destres, Dexolam, Diprex, Himzolam, Imprax, Mediprex, Omelam, Onapract, Pizolam, Plaxid, Prolam, Pronil, Prosanti, Resolin, Resto, Richpram, Sanprazole, Serxanti, Sinzolam, Somnirest, Synozolam, Tenschem, Tryzo, Ziety, Zolar, Zolin, Zoltweet, Zopral

Similar Products:
Aldara, Allegra, Sovaldi, Biaxin, Tenormin, Elocon, Crestor, Zebeta, Floxin

Also known as: Alprazolam


{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprotame XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprotame XR dosage information

Side effects

The most common side effects associated with Alprotame are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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Clinical, orthodontic and radiological findings in the jaws and face of children with dysmelia associated with thalidomide-embryopathy. It also displays good activity against atypical pathogens, such as Mycobacterium avium complex, Helicobacter pylori and Borrelia spp. Milder versions of aversive smoking seem to lack specific efficacy. We find that numeracy and cognitive reflection are positively associated with enrollment likelihood and that they are more important determinants of enrollment than age. Combination antiretroviral therapy in human immunodeficiency virus-infected pregnant women. Healthcare providers working in addiction facilities do not often implement integrated treatment of comorbid substance use disorder (SUD) and posttraumatic stress disorder (PTSD) while there is empirical evidence to do so. Influence of prepartum chronic ultramild stress on maternal pup care behavior in mice. Increased BMI causes a decrease in the stiffness of plantar fascia and an increase in the thickness of the plantar fascia as well as the thickness and stiffness of HP.

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In a search for natural stimulators, we found that tumor necrosis factor-alpha, in itself and synergistically with interleukin-1 beta, induced activin A/EDF production in both cell lines. Our results suggest that, unlike Parkin, pathogenic DJ-1 mutations seem to be restricted in certain populations and are unlikely to be of clinical importance in the eastern part of India. RNA silencing is a conserved eukaryotic pathway involved in the suppression of gene expression via sequence-specific interactions that are mediated by 21-23 nt RNA molecules. People with serious mental illnesses and co-occurring substance use disorders are often excluded from vocational services, despite the lack of evidence that having a substance use disorder prevents them from being able to work. Like dexamethasone, peptides containing E-Q-E-Y-V from the N-terminal domain of LC1 also blocked ligand-induced association of Grb2, p21(ras) and Raf. The infusion of prostaglandin E1, a vasodilating substance with predominant effects on the pulmonary vasculature, has been found effective in the management of pulmonary hypertension associated with various diseases. Multiplex PCR assay for genotyping of Mycobacterium tuberculosis in Lima, Peru. The involvement of the photo-conversion of protochlorophyll to chlorophyll and other photoreceptor systems in the labeling of RNA during chloroplast development has been considered by comparing the labeling pattern obtained with wild-type cells with the patterns obtained with mutants of Euglena which either lack detectable amounts of protochlorophyll and chlorophyll or form only rudimentary chloroplasts upon light induction.No significant difference in RNA content between dark-grown, non-dividing cells containing fully developed chloroplasts and the same cells maintained in darkness for the development period can be detected. We showed that LIN-12/Notch was activated in the undifferentiated type II vulval muscle cells by LAG-2/DSL that is likely produced by the anchor cell (AC). IgG concentrations were determined retrospectively in 41 paired fetal/maternal (f/m) samples in 31 Rh (D) alloimmunized pregnancies.

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To determine whether the rates of death and complications of carotid endarterectomy (CE) were different in the octogenarian population than in patients younger than age 80. Therefore an active role of AM in human and experimental bronchoconstriction must be considered. However, the water quality indicators correlated with the increase in urban population and per capita waste production in the city. The concentrations of IL-2 and IFN-gamma proteins secreted from UCB-MSCs were then quantified using enzyme-linked immunosorbent assay. Testing facility for hydrogen storage materials designed to simulate application based conditions.

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Decidual vasculopathy and extensive placental infarction in a patient with repeated thromboembolic accidents, recurrent fetal loss, and a lupus anticoagulant. Non-obese asthmatics had more frequent visits to their general practitioner/Emergency medical services (GP/EMS) during the last month compared to obese asthmatics, which is a new finding inconsistent to any study conducted before. Anti-inflammatory effects of insulin and the pro-inflammatory effects of glucose. A total of 123 severe achalasia patients who underwent POEM from August 2011 to May 2013 were included. The author advocates: (1) The introduction and use of periodontal index e.g. To investigate this further, we infected resistant DBA/2 (DBA) and susceptible C3H/HeJ (C3H) mice in the hind footpads and monitored arthritis development for 21 days. Application of these assays at an individual level is far more questionable because of person-to-person variability in the antibody response and the course of HIV infection, and because of the prospective regulatory approval requirements.

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Expression and function of a variant T cell receptor complex lacking CD3-gamma. This study tested a hypothesis that tissue-selective targeted decorin gene therapy delivered to the stroma with adeno-associated virus serotype 5 (AAV5) inhibits corneal fibrosis in vivo without significant side effects. The findings of the present study highlight the importance of considering self-excited oscillation of the vocal folds in elucidation of the phonation mechanism. Phenotypes of seven known IDS variants were consistent with the literature. Improvement in glucose control, in the absence of weight gain, leads to lower triglyceride and higher HDL cholesterol levels. The relationship between mutual family relations and child psychopathology. Although nematode (Caenorabditis elegans) and sea urchin (Strongylocentrotus purpuratus) have IL17 and IL17 receptors, we found no CIKS in their genomes. Active management involves administration of a prophylactic oxytocic after delivery, early cord clamping and cutting, and controlled cord traction of the umbilical cord.

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We postulated that peripheral infusion of IL-12 along with irradiated tumor cells can lead to immunological rejection of 9L glioma. Lead silicate microstructured optical fibres for electro-optical applications. The specific primers were designed based on the ITS1-5.8S-ITS2ITS (Internal Transcribed Spacers of rRNA genes) multicopy region. A spinach PEAMT cDNA was isolated by functional complementation of a Schizosaccharomyces pombe cho2(-) mutant and was shown to encode a protein with PEAMT activity and without ethanolamine- or phosphatidylethanolamine N-methyltransferase activity. Inhibition of mast cell-mediated anaphylaxis by sochungryong-tang. For a novel needle-free injection (NFI) system, the relationship between frequency of wet or incomplete injections and device-related factors and subject physiological variables was examined.

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The contribution of hydrogen peroxide resistance to virulence of Mycobacterium tuberculosis during the first six days after intravenous infection of normal and BCG-vaccinated guinea-pigs. These results suggest that the protective effect of estradiol-17 beta against the acute hepatotoxicity of aflatoxin B1 is mainly due to an antagonistic interaction of both compounds on the synthesis of nucleic acid in nucleolus. Studies on the action of this enzyme towards chemically modified glycans revealed that the carboxyl groups of muramic acid residues are indispensable to a substrate for this enzyme. These results suggest that the pro-apoptotic effect of PI 3-K inhibitors on TRAIL-mediated apoptosis may contribute to both the extrinsic and intrinsic pathways. Purine nucleoside synthesis, an efficient method employing nucleoside phosphorylases. Lipedematous alopecia is an unusual disorder characterized by short, brittle scalp hairs associated with thickening of the scalp by adipose tissue. Tumorigenicity in the nude mice injected with antisense GLUT1 expressing cells was significantly slower than in those with wild-type MKN45 cells.

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Returning to sports after periacetabular osteotomy for developmental dysplasia of the hip. Recognition of chylomicron remnants and beta-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver alpha 2-macroglobulin-recognition site. Pathological mitochondrial DNA (mtDNA) rearrangements have been proposed to result from repair of double-strand breaks caused by blockage of mitochondrial DNA (mtDNA) replication. Elevated concentrations of synthetic fluorinated glucocorticoid analogs transiently increase in the intracellular exchangeable calcium in cultured bone cells. Analysis of 351 pairs of parameters helped single out several combinations informative as regards hepatitis prognosis. Multidisciplinary team (MDT) management in thoracic oncology has been introduced over the past two decades with the aim of improving outcomes for patients. Formamicin was extracted with acetone from cultured mycelia and purified by silicagel and Sephadex LH-20 column chromatographies and CPC (Centrifugal liquid-liquid Partition Chromatography). The predictive value of the abnormality side during digital rectal examination (DRE) has never been studied, suggesting that physicians examined the left lobe of the gland as well as the right lobe. As the performance of those two subgroups did not reveal significance, the subgroups were combined for further analyses.

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The main clinical picture is a plavix dosing relative new entity characterized by progressive ulcerative proctitis, the so called anorectal syndrome. To investigate the clinicopathological features and prognosis of patients with the malignant transformation of sinonasal inverted papilloma. Atorvastatin added to interferon beta for relapsing multiple sclerosis: 12-month treatment extension of the randomized multicenter SWABIMS trial. Major rises over recent years were observed in France (from 0.8/100,000 in 1985-1989 to 2.2 in 2000-2003) and in Spain (from 0.8 in the 1985-1989 to 1.7 in 2000-2004). Treatment of retruded maxilla in cleft lip and palate--orthognathic surgery versus distraction osteogenesis: the case for orthognathic surgery. In order to demonstrate the performance of the reactor, SiO2 particles have been coated with TiO2 using tetrakis-dimethylamino titanium (TDMAT) and H2O as precursors.

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On subsequent evaluation, she was found to have a follicular lymphoma. An intercurrent metabolic stress such as infection, endocrinopathy, or alcoholism may be a precipitating factor. Pulse-chase analysis of the biosynthesis of mutant TfRs that lack the membrane-proximal cytoplasmic domain show that they exit the endoglycosidase H-sensitive compartment at a slower rate than the wild type TfR. The objective was to examine the importance of phenergan drug schedule type of service-system, level of care, length of inpatient stay, gender, age, and diagnosis on rates of involuntary admission, by comparing one deinstitutionalized and one locally institutionalized service-system, in a naturalistic experiment. The involvement of TNF, IL-1 and IL-6 in the immune response to protozoan parasites.

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Separation of ribonucleic acids by polyacrylamide gel electrophoresis. Greater dietary diversity is associated with lower emergency and hospitalization utilization and expenditures, but not lower use of ambulatory services. Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection. Baclofen inhibits more effectively C-afferent than Adelta-afferent glutamatergic transmission in substantia gelatinosa neurons of adult rat spinal cord slices. In this study, we identified and characterized a novel Pi starvation-responsive gene, MYB1, encoding an R2R3-type transcription factor in rice. Identification of oxidized protein hydrolase as a potential prodrug target in prostate cancer. With the high incidence of supplement use in the military population, caution and further investigation into supplement use with correlation to the incidence of liver cancers may be warranted. A case of Rothia dentocariosa bacteremia periactin max daily dose in a patient receiving infliximab for ulcerative colitis.

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In the immune system, cell surface S1P(1) receptors transduce the rapid, transient effects of extracellular S1P on T- and B-lymphocyte trafficking in the lymphoid system, lymphocyte migration in non-immune tissues and cytokine generation. Each of these six interneurons has a different directional response to wind stimuli. To study the effect of Erigeron Breviscapus (EB) at different concentrations and different intervention time points on the mRNA and protein expression of OPG/RANKL/RANK in MG63 osteoblast-like cells and RAW264. Formulation design, development and in-vitro evaluation used in this study may serve as rational approach for manufacturing taste-masked orodispersible dosage forms. To study what type of drug class is cymbalta the distribution of nitric oxide synthase (NOS) in the enteric nervous system of children with cardiac achalasia. Prediction of atopic dermatitis in 2-yr-old children by cord blood IgE, genetic polymorphisms in cytokine genes, and maternal mentality during pregnancy. mauritiana (endemic to Mauritius) and Afrotropical strains of the two cosmopolitan species D.

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Selected muscle biopsy specimens with a range of neuropathologic diagnoses, including fiber type grouping, Type II atrophy, and congenital fiber type disproportion, were also assessed for immunoreactivity. This procedure requires involvement of the radiologist, surgeon, and pathologist. Histophotometric study of quantitative variation of DNA in the nuclei of the gingival epithelium in relation to age. Association of Mild-to-Moderate Reduction in Glomerular Filtration Rate with Subclinical Atherosclerosis in Postmenopausal Women. Interleukin-1 enhances the development of type II collagen-induced arthritis only in susceptible and not in resistant mice. Keeping in view of the high multiple correlations, nomograms have been constructed to predict birth weights from head and chest circumferences in male and female new born babies. Induction of type B synoviocyte-like cells from plasmacytoid dendritic cells of the bone marrow in rheumatoid arthritis and osteoarthritis. The method was evaluated in the heart in seven volunteers at 3.0T. A single mutation turns a non-binding germline-like predecessor of broadly neutralizing antibody into a binding antibody biaxin antibiotic used to treat to HIV-1 envelope glycoproteins.

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However, the condyles were located more posteriorly in all tomographic sections (P less than 0.05 for lateral, P less than 0.001 for central and medial) in patients with clicking than in those without. It has been shown that the talus slides as well as rolls during the ankle arc of motion from plantarflexion to dorsiflexion. A comprehensive cognitive test battery was administered to 28 abstinent ecstasy users with concomitant use of cannabis only and to two equally sized matched groups of cannabis users and non-users. No significant differences could be demonstrated for the remaining hormones. The isolates were characterized by hemagglutination- and neuraminidase-inhibition assays and by sequencing the hemagglutinin gene and phylogenetic analysis. A reliable, noninvasive assessment of plaque configuration would constitute an important step forward for predicting complications following percutaneous coronary intervention (PCI). Care models addressing social risk factors are needed to meet the aging-in-place challenges of subsidized housing residents. Trial of folate treatment to prevent recurrence of neural tube defects.

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Doxycycline (DOXY) and chemically modified tetracyclines (CMTs), previously known as inhibitors of the matrix metalloproteinase (MMP)-dependent proteinase cascade, down-regulated the mRNA and protein expression of trypsinogen-2 by COLO-205 human colon adenocarcinoma cells at therapeutically attainable concentrations (0. A well-known complication of ifosfamide therapy is transient acute kidney injury. Occurrence, distribution and relationship to changes i catecholamine synthesis. Primed neutrophils injure rat lung through a platelet-activating factor-dependent mechanism. The estradiol antagonists 4-hydroxytamoxifen and ICI 164,384 as well as other steroid hormones were unable to activate this hydrolytic activity. The interviews were tape recorded, transcribed and analysed thematically. Patients with progressive, symptomatic recurrent or disseminated disease unresponsive to hormonal and/or isotopic treatment were eligible. Age differences in somatotypes of Garhwali males 17-60 years of age.

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A distinctive, outwardly rectifying, depolarization-induced Cl- channel (ORDIC channel) has been proposed to account for the Cl- conductance that is defective in CF. Other agents that inhibit alternative targets such as the mammalian target of rapamycin (mTOR) have also demonstrated activity. IUGR was investigated by examining the expression of main factors controlling fetal growth. 15(S)-HETE also induced tyrosine phosphorylation of Janus kinase 2 (Jak2) in VSMCs, and its inhibition substantially reduced STAT3 phosphorylation, MCP-1 expression, and VSMC migration. HSP27 also displayed an up-regulated expression in the ROSM in 24h after the irritants exposure for 15min. Separations of PS beads of different surface functionalization (COOH and none) and different sizes (6, 10, and 15 microm in diameter) are demonstrated. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. The facial branchiomotor neurons (FBMNs) undergo a characteristic tangential migration in the vertebrate hindbrain. The latissimus dorsi flap, because it requires special positioning of the patient, has not been as popular as the pectoralis major flap, but both have excellent blood supplies and will reach almost any area of the face and neck to fill defects and cover internal or external surfaces. From these findings, it prilosec 80 mg is concluded that testosterone can promote the induction of the pancreatic tumors in rats by HAQO.

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Cancer type and stage, surgical procedure, hemoglobin values, pRBC transfusions, intraoperative blood loss, and postoperative complications were collected. A correlation appeared to exist between the K1 of these compounds for succinic semi-aldehyde dehydrogenase, the second enzyme in the degradation of GABA, and the doses exerting a maximum effect on behavior. To examine whether there exists an interaction between breaks and radiation induced lesions, MRh12/Cy males were crossed to Berlin K females and the male progeny from this cross carrying the MR or Cy chromosome were irradiated. Cases of Type 2 diabetes prevented, cost (Euro), incremental cost-effectiveness ratios (ICERs). Feasibility of Axillary Reverse Mapping and Clinicopathological Features Predicting ARM Node Metastasis in Breast Cancer-a Pilot Study. Because NEP is important in modulating the airway effects of endogenously released tachykinins after tracheal infusion of capsaicin, but ACE is not, it seems likely that tracheal administration of capsaicin releases tachykinins from epithelial rather than endothelial loci. It is best to terminate preparations above the gingival margin but for retention and esthetics considerations the margins of the fixed restorations could be placed subgingivally. We investigate the dynamics of charged microparticles at polydimethylsiloxane (oil)-water interfaces using Pickering emulsions as an experimental template. The importance of the use of DNA-technologies in genetics, breeding and seed-production of maize is shown. In knee OA, the knee radiograph femur-tibia and full-limb radiograph hip-knee-ankle angles were correlated.

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