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Alprine (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprine, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprine is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Alcicalm, Alflux, Alpaz, Alpkair, Alpra, Alrif, Alsert, Alzep, Alzocum, Alzokam, Anzilum, Aryalam, Cooltime, Emlol, Ezoprax, Fledore, Fluxin, Omelam, Plxna, Pyrex, Restyl, Sertakem, Tenlax, Texidep

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Also known as: Alprazolam


Alprine is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprine is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprine if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprine or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprine. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take Alprine XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alprine XR may be habit-forming and should be used only by the person it was prescribed for. Alprine XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alprine extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alprine XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alprine XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alprine XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alprine XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alprine XR dosage information


If you have been prescribed Alprine for medical reasons, the best way to avoid a Alprine overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprine consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprine dosage information

Side effects

The most common side effects associated with Alprine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alprine if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alprine or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alprine, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alprine. This medication can increase the effects of alcohol.

Alprine may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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Prostate cancer with different ERG status may show different FOXP3-positive cell numbers. The structural characterization of each chimeric protein indicates that the important information on the structure formation is encoded in the beta-scaffold region. Effects of biotic and abiotic factors on the distribution and abundance of larval two-lined salamanders (Eurycea bislineata) across spatial scales. The performance of the Inogen One G2 POC and the EverGo POC had comparable performance with that of the compressed oxygen cylinder during walking in patients with ILD and exertional desaturation. Under a light-dark cycle of LD 12:12 (lights on at 07:00), a subcutaneous injection of 10 microg of melatonin at two times during the day (at 11:00 and 11:30) did not increase the number of SR. When an antibody was used which recognizes the midregion of CCK-58, an additional peak was detected which eluted between CCK-33-39 and CCK-58.

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9a, 12a-Octadecadiynoic acid (Ro-3-1314) a potential inhibitor of linoleic acid metabolism, stimulated the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substances of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments. Increased use of the emotion-focused coping processes of tension reduction and positive reappraisal was correlated with lower levels of baseline heart rate, whereas distancing was associated with higher levels of systolic blood pressure reactivity during the conflict task. By understanding the role of specific cavity dimensions on fracture resistance, useful clinical guidelines concerning MOD morphologies are formulated. Genotyping of Protein Z G79A and Endothelin-1 G5665T was carried out by polymerase chain reaction-restricted fragment length polymorphism (PCR-RFLP) assay for 100 SCD patients and 100 controls. Inhibition of ACE mainly results an overall antihypertensive effect. To investigate the role of GH in the control of apoptosis, Ba/F3 cells expressing either the wild-type rat GHR (Ba/F3 GHR) or a mutated rat GHR (Ba/F3 ILV/T) were used. Studies have shown that excessive iron deposits in the liver due to hereditary hemochromatosis leads to cirrhosis, which can put an individual at increased risk for developing hepatocellular carcinoma.

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To update community psychiatry principles within the context of increased outpatient services. Here, we have shown that the interaction of EGFR and STAT3 increased in the nucleus in the presence of LMP1. The TCR gamma gene characteristics of 73 cases of lymphocytic leukemia and lymphoma and other diseases that had presented 1 or 2 prominent bands of amplified TCR gamma VI subgroups-J1/2 gene rearrangement (GR) were detected by polymerase chain reaction-restriction enzymes (PCR-RE), heteroduplex formation (HDF), DNA sequencing and single-strand conformational polymorphism (SSCP). The Nature Index: a general framework for synthesizing knowledge on the state of biodiversity. It is concluded that treatment with hCG/LH may favour seizure onset in the presence of potentially epileptogenic lesions such as an intracranial dermoid cyst. Investigation on the solubilization of polycyclic aromatic hydrocarbons in the presence of single and mixed Gemini surfactants. Children with cancer must cope not only with their disease and its treatment but also with the environment in which treatment is given. The study was carried out with the aim of determining the factors affecting and to evaluate anxiety situations and self-esteem of children with and without mentally retarded siblings.

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Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor. Serum albumin is abundantly contained in human serum and plays many physiologic roles. Mortality statistics as measures of need for outpatient services. Diaphragmatic dysfunction, a major driver of dyspnea and mortality, is associated with a shift of the burden of ventilation to extradiaphragmatic inspiratory muscles, including neck muscles. Heat shock proteins are induced by several stress factors and are potential antigens in autoimmune disorders. Abstracts of the 6th International Conference on cGMP: Generators, Effectors and Therapeutic Implications, 28-30 June 2013, Erfurt, Germany.

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Characteristics of gas exchange with the surrounding atmosphere across the skin and mucosa. A retrospective case series of 159 consecutive patients hospitalized in San Antonio, Tex, for acute, first-ever stroke compared risk factors, features, and causes of stroke between Mexican Americans and whites. Immunoelectron microscopy localized eight of these components to different parts of the spindle. Methods used in the analysis of the data chi-square and t-tests in dependent groups. No significant correlation was found between sport/recreation involvement and education/employment status. With inefficient chemotherapy, it is urgent to develop new strategies for tumour therapy. Sporulation and survival of Toxoplasma gondii oocysts in different types of commercial cat litter.

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Effects of hearing aid amplification and stimulus intensity on cortical auditory evoked potentials. This review focuses on plasminogen activator inhibitor-2 (PAI-2) in terms of the molecular structure-function relationships and its intracellular functions, in particular in relation to apoptosis. Decreased level of the PMNs phagocytic activity was found in the acute elavil medication reviews phase of salmonellosis. It has performed a review of these treatment methods, which it aims to circulate, and it is seeking to develop recommendations in order to allow nationwide implementation of innovative approaches while promoting good use thereof. One is a relatively narrow emission band in the ultraviolet region (360 nm), while the other is a broad emission band in the visible region (468 nm).

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Precipitating antibody in the sera of patients treated cryosurgically for carcinoma of the prostate. Three latent classes of overweight and obese children were identified: High Satiety Responsive, High Food Responsive, and Moderate Satiety and Food Responsive. Valproate reduced brain aspartate but did not increase moduretic tablets weight loss brain GABA levels in infant mice. We report a patient who developed urachal carcinoma 18 years after kidney transplantation. NaF inhibition of the initial binding of aminoacyl-sRNA to reticulocyte ribosomes. The non-insulin-dependent diabetic (NIDDM) patient with mild fasting hyperglycemia commonly has mild hypertriglyceridemia due to overproduction of TG-rich lipoproteins in the liver, associated with decreased high-density lipoprotein (HDL) cholesterol levels. By using Flp recombinase-mediated integration, the system allows the integration and expression of a series of reporter gene constructs at exactly the same genomic location and orientation in all cells of any one culture.

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To test this hypothesis, rats were divided into control, diabetic, and insulin-treated diabetic groups. The use of such a retractor and cardiac stabilizer is described. In the new born, clinical seizures occurred mainly in active-REM sleep in contrast to those in the older children and adults. High-density lipoprotein cholesterol and apolipoprotein A-I levels at diagnosis in patients with non-insulin dependent diabetes. In normal cases, the calculations were done every second week from 33 to 38 weeks of gestation, and the difference in variance among three gestational ages in each artery was tested by a one-way ANOVA. The clinical features of two patients with serologically proven acute murine typhus with ocular involvement are presented. Recent developments in the field of molecular modeling of polysaccharides offer new opportunities to reexamine the structural basis underlying the formation and stabilization of ordered structures and their interactions with counterions.

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Effects of interferons on cultured human melanocytes in vitro: interferon-beta but not-alpha or -gamma inhibit proliferation and all interferons significantly modulate the cell phenotype. Here we analyze the basis of optimal strategies that microorganisms can use to cope with this tradeoff. Captopril in renovascular hypertension: long-term use in predicting surgical outcome. Evolutionary insights about bacterial GlxRS from whole genome analyses: is GluRS2 a chimera?. Laboratory monitoring of parenteral nutrition-associated hepatic dysfunction in infants. The benefits of partnering were greater for men than women and transition into parenthood was of greater benefit to women.

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Nuclear localization of cyclin B1 controls mitotic entry after DNA damage. The role of diastolic outward current deactivation kinetics on the induction of spiral waves. We determine whether urologists caring for men with prostate cancer accurately captured the nuances of quality of life, as disclosed by patients in validated, self-administered health related quality of life instruments. PTP61Fn effectively repressed the eye overgrowth associated with activation of the epidermal growth factor receptor (EGFR), PTK, or the expression of the platelet-derived growth factor/vascular endothelial growth factor receptor (PVR) or insulin receptor (InR) PTKs. However, for tortuous aortas large non-rigid deformations occur, thus a non-rigid registration must be performed to enable an accurate overlay.

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Pediatric psychocutaneous disorders: a review of primary psychiatric disorders with dermatologic manifestations. The PUVA-induced murine skin edema is provoked on the dorsa of female hairless albino mice and measured with a hand-held micrometer. Determination of urinary and serum beta-glucuronidase and alkaline phosphatase in various renal disease and kidney rejection transplanted patients. Palladium-catalyzed arene C(sp2)-H acetoxylation has emerged as a powerful tool to construct a carbon-oxygen (C-O) bond. Odor information appears to be encoded is biaxin a sulfa drug by activity distributed across many neurons at each level in the olfactory pathway. However, subclinical hyperthyroidism is associated with deleterious effects on cardiovascular and skeletal systems. Optic atrophy (OA) and sensorineural hearing loss (SNHL) are key abnormalities in several syndromes, including the recessively inherited Wolfram syndrome, caused by mutations in WFS1. In conclusion, among the tea polyphenols tested, ECg was considered to be the agent with the most potential antimetastasis activity because it inhibited invasion in the absence of cytotoxicity. Evaluation of the carcinogenic potency of 4 environmental polycyclic aromatic compounds following intrapulmonary application in rats.

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Bringing evidence to practice is a key issue in modern medicine. The multi-layer slab is mimicked by a many-body embedded-atom potential energy function. Lophomonas blattarum, a rare protozoa, was involved in pulmonary infections of transplant recipients. In general, drugs which have been shown by electrophysiological studies to cause changes in the activity of NE neurons in the locus coeruleus also alter the brain levels of MHPG. Additionally, 72 metabolites were tentatively identified and changes in their relative concentration during growth were individually analysed.

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Physical and Clinical Evaluation of Hip Spica Cast applied with Three-slab Technique using Fibreglass Material. To advance our knowledge of the mechanisms generating both abnormal pain and analgesia (drugs and surgical techniques) in patients is the main motivation of such anexciting challenge. In this work, we found that treatment of human breast cancer (MCF-7) cells with 15d-PGJ2 led to time-dependent increases in the expression of HO-1. Anesthetic management of abdominal gunshot wound--a report of roxithromycin composition brand name three cases. Analyses of epitopes and biological activity were made on two preparations of recombinant human thyrotropin produced in Chinese hamster ovary cells. Poor adherence to antihypertensive medication is one possible reason why success in clinical trials has not been translated into everyday practice. In case of twin pregnancies the high levels of E2, progestins and A were stimulated and augmented in accordance with the increase of endogenous HCG secreted from the trophoblast. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Various artificial porphyrin receptors have been synthesized for the recognition of biologically important chiral guests such as carbohydrates, amino acids, and their derivatives.

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Additive value for ultrasonographic signal in a screening algorithm for patients presenting with acute mono-/oligoarthritis in whom gout is suspected. Evaluation of the microbial safety of child food of animal origin in Greece. The elimination of organic acids enabled the description of the samples, which were evaluated as bitter, persistent and slightly astringent. Focal absence of laminin and type VII collagen from the BM of some ameloblastomas and the presence of Onc-cFn in the ECM of most ameloblastomas may correlate with their aggressive behaviour. Alkaline phosphatase activatable polymeric cross-linkers and their use in the stabilization of proteins. A group uptake and transport of HRP were obtained with both application techniques, when sufficiently long survival times (8-11 days) were used. Total RNAs from RP and control retinas were used to generate radiolabeled cDNA probes to screen gridded membrane arrays of 205 apoptosis-related genes. Reporter groups considered include radioactive, fluorescent, and chemiluminescent nucleotides, as well as enzymes with colorimetric, fluorescent, and luminescent substrates.

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Cryobiology of articular cartilage: ice morphology and recovery of chondrocytes. Although much research has been focused on acquired resistance phenotypes, we believe that de novo drug resistance mechanisms may be an important component in protecting cells from initial drug exposure. In contrast, chloroquine, an autophagy inhibitor, counteracted hyperbaric oxygen analgesic effect. False negative results may be get because of limited biopsy material. Pelvic ring injuries usually result from high-energy trauma, and cranial and abdominal multiple injuries are frequently present. To prospectively evaluate the usefulness of DP in patients with acute pancreatitis (AP), analyzing its capabilities for determining the incidence of necrosis, and as a prognostic predictor. A significant association between stressful life events and anxiolytics and/or antidepressants use was observed. Thirty months after the operation the patient is in a good overall condition and no recurrence has been observed. Benign chondroid syringoma: report of a case clinically mimicking a malignant neoplasm.

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