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Alfatrim (Trimethoprim)

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Alfatrim (sulfamethoxazole / trimethoprim) is absorbed by the body and begins to kill bacteria within 1 to 4 hours after taking your dose. For more common problems like urinary tract infections and ear infections, most people will start to feel relief after a few days.

Other names for this medication:
Actrim, Bactricida, Bactrizol, Bactropin, Biseptrin, Ciplin, Colizole, Cotribene, Cotrimol, Cotripharm, Danferane, Globaxol, Irgagen, Megatrim, Methotrin, Metrim, Novidrine, Oriprim, Primotren, Purbac, Servitrim, Sulfatalpin, Sulphatrim, Sulphytrim, Trimethazol, Trimethoprim, Trimoxsul, Vanasulf, Wiatrim

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Also known as: Trimethoprim


Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain sulfamethoxazole and trimethoprim. It may not be specific to Alfatrim DS. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). .

For patients taking the oral liquid, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (liquid or tablets): For treatment of bacterial infections: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Your doctor may adjust this dose if needed. Children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 40 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 8 milligrams (mg) per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. Weighing 40 kilograms (kg)—4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Weighing 30 kg—3 teaspoonfuls (15 mL) of oral liquid or 1 ½ tablet 2 times a day for 10 days. Weighing 20 kg—2 teaspoonfuls (10 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Weighing 10 kg—1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. Children younger than 2 months of age—Use is not recommended. For treatment of bronchitis: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended. For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 75 to 100 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 15 to 20 milligrams (mg) per kilogram of body weight of trimethoprim each day, given in equally divided doses every 6 hours for 14 to 21 days. Weighing 80 kilograms (kg)—10 teaspoonfuls (50 milliliters (mL)) or 5 tablets (or 2 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 64 kg—8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Weighing 48 kg—6 teaspoonfuls (30 mL) or 3 tablets (or 1 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 40 kg—5 teaspoonfuls (25 mL) or 2 ½ tablets 4 times a day for 14 to 21 days. Weighing 32 kg—4 teaspoonfuls (20 mL) or 2 tablets (or 1 DS tablet) 4 times a day for 14 to 21 days. Weighing 24 kg—3 teaspoonfuls (15 mL) or 1 ½ tablets 4 times a day for 14 to 21 days. Weighing 16 kg—2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. Weighing 8 kg—1 teaspoonful (5 mL) 4 times a day for 14 to 21 days. Children younger than 2 months of age—Use is not recommended. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor. The usual dose is 750 mg of sulfamethoxazole and 150 mg of trimethoprim per square meter (m[2]) of body surface each day. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Children younger than 2 months of age—Use is not recommended. For treatment of traveler's diarrhea: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended.


If you overdose Generic Alfatrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alfatrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfatrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Alfatrim if you are allergic to Generic Alfatrim components. Do not take Generic Alfatrim if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Alfatrim can harm your baby. Do not take Generic Alfatrim if you have anemia. Generic Alfatrim can't be given to children younger than 2 months old. Avoid exposure to sunlight, sunlamps, or tanning beds while taking Generic Alfatrim. Be careful with Generic Alfatrim if you have kidney or liver disease, folic acid deficiency, asthma or severe allergies, AIDS, glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); if you are malnourished. Be careful with Generic Alfatrim if you take seizure medication such as phenytoin (Dilantin); diuretic (water pill); blood thinner such as warfarin (Coumadin); methotrexate (Trexall, Rheumatrex); methotrexate (Trexall, Rheumatrex); or an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace) or trandolapril (Mavik). It can be dangerous to stop Generic Alfatrim taking suddenly.

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BLOOD LEVELS AND URINARY EXCRETION IN PEANUT OIL, BEESWAX AND PENICILLIN MIXTURE. Calcium channel block by (-)devapamil is affected by the sequence environment and composition of the phenylalkylamine receptor site. Although meralgia paresthetica is not considered a lopressor 100 mg frequent complication of laparoscopic appendectomy, it should be taken into account to avoid nerve lesion. Histological examinations revealed that 14-day tail suspension caused a loss of secondary cancellous bone with a reduction in the trabecular number and thickness in comparison with control rats. Regulation of expression of the Rhizopus oryzae uricase and urease enzymes. Poor resistance of the cardiovascular system to circulatory hypoxia during shock development is considered to be dysregulatory pathology.

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Isolation and expression analysis of a Pax group III gene from the crustacean Cherax destructor. The partitioning coefficients of phenanthrene between the emulsified arcoxia 90 mg precio pami phase and the aqueous phase, Kem, is slightly larger than those between the micellar pseudo phase and the aqueous phase, Kmc. Mycophenolate mofetil (MMF) is an oral and well tolerated immunosuppressant agent which has proved its efficacy in pemphigus and some bullous pemphigoid. The observations that conditioned medium from Ras-, but not Raf-, transfected RIE-1 cells, as well as exogenous transforming growth factor alpha (TGFalpha), promoted morphological transformation of parental RIE-1 cells prompted us to identify epidermal growth factor (EGF) receptor (EGFR) ligands produced by Ras-transformed RIE-1 cells responsible for this autocrine effect. Subjects generally underestimated the extent of the pursuit eye movements relative to estimates made after saccades. We determined whether plasma lipoproteins at baseline and then at 6 weeks after randomization predicted clinical outcome.

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The relationship between genotype and phenotype is being analysed, and ADA deficiency has become a focus for novel approaches to enzyme replacement and gene therapy. phenergan dextromethorphan dose We conducted a systematic search of relevant databases according to pre-defined criteria. Auditory findings, including the auditory-evoked brainstem potentials, suggested impairment of the distal tract of the right VIII cranial nerve. Intraoperative computerized navigation for flapless implant surgery and immediate loading in the edentulous mandible. Within the context of safe, supportive, stable, and socially responsible therapeutic communities, a trauma recovery treatment framework is used to teach youths effective adaptation and coping skills to replace nonadaptive cognitive, social, and behavioral strategies that may have emerged earlier as means of coping with traumatic life experiences. Cloning and strong expression of a Bacillus subtilis WL-3 mannanase gene in B. Because immunodetection does not distinguish between active and inactive UGT, comparison of normalized activity between different batches of a recombinant UGT, mutants of a given UGT, or different UGTs is prone to large inaccuracies. Cutting efficiency of K-files manufactured with different metallic alloys.

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Fibroblast-like coreg generic carvedilol cost synoviocytes from rheumatoid arthritis patients have intrinsic properties of follicular dendritic cells. In bar-probe partial report experiments, subjects are presented with a brief array of letters, followed by a cue that singles out a target letter. We here describe a transgenic approach that allows identification, in vivo visualization, isolation, and accurate enumeration of various classes of stem and progenitor cells in the adult brain. These ground motions caused large deformation and possible collapse of the frame building, and they required exceptional measures in the design of the base-isolated building if it was to remain functional. Evaluation of oxidative stress, the activities of paraoxonase and arylesterase in patients with subclinic hypothyroidism. Because each of these women was initially given a benign diagnosis, they received no treatment beyond the diagnostic biopsy. Despite this opportunity for recognition and advancement in the current healthcare system, variations in educational preparation, public confusion about the various roles and titles within advanced practice nursing, and differing professional certifications plague the opportunity for an elevated status of advanced practice nursing.

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Disinhibition of the paraventricular nucleus (PVN) by injection of bicuculline causes pressor, tachycardic and renal sympathoexcitatory responses mediated via an angiotensinergic projection from PVN to RVLM. Due to steric hindrances a restriction in the angle of head group rotation occurs at lower temperatures but is greatly reduced above the main transition. Alterations in the form prevacid fastab pediatric dose of the ventricular complex of the electrocardiogram produced by myocardial infarction complicated by bundle branch block. Starch, alginate, chitosan or Carbopol microparticles, containing the test protein bovine serum albumin (BSA), were prepared by spray-drying and characterized by laser diffraction and scanning electron microscopy. Appendiceal stump closure in children with complicated appendicitis: a prospective analysis of endoloops versus endostaples.

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Protection of Rainbow Bridge National Monument: An exchange of views on the effects of Glen Canyon dam shows that complex problems remain to be solved. Control hop clones derived from tissue cultures, treated by thermotherapy and maintained in greenhouse were virus-free. Intimal hyperplasia was induced in rat carotid arteries by passage of a balloon catheter. Allogeneic transplantation for multiple myeloma: late relapse may occur as localised lytic lesion/plasmacytoma despite ongoing molecular remission. We propose that the approach described here provides a useful in vitro approach for the identification of transcriptional regulators of the CYP3A4 gene. Such hemorrhages appeared to be related to the early death of many premature infants.

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At 7 days after radiation, the ratio of necrotic cells in the crypt vs. Delayed emergence process does not result in a lower incidence of emergence agitation after sevoflurane anesthesia in children. Highly differentiated energy-demanding tissues, such as neurons and muscle cells, are often affected. Antimicrobial susceptibility testing by the disk diffusion method was conducted for neomycin, gentamicin, streptomycin, chloramphenicol, ofloxacin, trimethoprim-sulfamethoxazole, tetracycline, ampicillin, nalidixic acid, nitrofurantoin, cephalothin, and sulfisoxazole. Spectrophotometric and visual analysis of internal dental bleaching utilizing laser and heat as catalyzing sources. The comparison of inducing specific CTL by two methods of leukemia cell antigen loading of DCs and fusion of DCs with leukemia cells. Feedback inhibition by the aromatic amino acids varied from strain to strain in terms of the type of inhibitory control, and the particular acid or acids which inhibited. The role of the anterodorsal thalami nuclei in the regulation of adrenal medullary function, beta-adrenergic cardiac receptors and anxiety responses in maternally deprived rats under stressful conditions.

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