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Alerdain (Desloratadine)
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Alerdain

Alerdain is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Alerdain is used to provide symptomatic relieve of allergic symptoms. Alerdain diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle.

Other names for this medication:
Alerdain, Alerta, Allerdain, Allerde, Allerede, Allergesic, Antialer, Biomon, Dazit, Delorta, Descare, Desent, Deslor, Desloranid, Desloratadine, Desloriv, Desnova, Dilora, Lorday, Loreta, Nelora, Neoloridin, Nucope, Otrivin, Reditabs, Rodera, Tastylora, Veromon

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Also known as: Desloratadine

Description

Desloratadine and pseudoephedrine is a combination of two medicines used to treat nasal congestion (stuffy nose), sneezing, and runny nose caused by hay fever.

Desloratadine works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

The pseudoephedrine causes narrowing of blood vessels. This leads to clearing of nasal congestion, but it may also cause an increase in blood pressure in patients who have high blood pressure.

This medicine is available only with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

This section provides information on the proper use of a number of products that contain desloratadine. It may not be specific to Alerdain Reditabs. Please read with care.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For patients using the oral disintegrating tablet form of this medicine:

Make sure your hands are dry. Do not push the tablet through the foil backing of the package. Instead, gently peel back the foil backing and remove the tablet. Immediately place the tablet on top of the tongue. The tablet will dissolve in seconds, and you may swallow it with your saliva. You do not need to drink water or other liquid to swallow the tablet.

For patients using the syrup form of this medicine: Use a calibrated measuring dropper or syringe to measure the direct dose for your child based on your doctor's instructions. Do not use a regular teaspoon. If you are unsure about how much of the syrup to give to your child, ask your doctor or pharmacist.

For oral dosage form (oral disintegrating tablets): For symptoms of chronic hives: Adults and children 12 years of age and older—5 milligrams (mg) once a day. Children 6 to 11 years of age—2.5 mg once a day. Children 4 to 6 years of age—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended . For symptoms of hay fever: Adults and children 12 years of age and older—5 mg once a day. Children 6 to 11 years of age—2.5 mg once a day. Children 4 to 6 years of age—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .

For oral dosage form (tablets): For symptoms of chronic hives: Adults and children 12 years of age and older—5 mg once a day. Children 4 to 12 years of age—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended . For symptoms of hay fever: Adults and children 12 years of age and older—5 mg once a day. Children 4 to 12 years of age—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .

For oral dosage form (syrup): For symptoms of chronic hives: Adults and children 12 years of age and older—2 teaspoonfuls (5 milligrams [mg] in 10 milliliters [mL]) once a day. Children 6 to 11 years of age—1 teaspoonful (2.5 mg in 5 mL) once a day Children 4 to 5 years of age—½ teaspoonful (1.25 mg in 2.5 mL) once a day Children and infants up to 4 years of age—Use is not recommended . For symptoms of hay fever: Adults and children 12 years of age and older—2 teaspoonfuls (5 milligrams [mg] in 10 milliliters [mL]) once a day. Children 6 to 11 years of age—1 teaspoonful (2.5 mg in 5 mL) once a day Children 4 to 5 years of age—½ teaspoonful (1.25 mg in 2.5 mL) once a day Children and infants up to 4 years of age—Use is not recommended .

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause anxiety, trouble sleeping, headache, vomiting, thirst, muscle weakness, fast or pounding heartbeats, hallucinations, shallow breathing, or a seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Desloratadine/pseudoephedrine dosage information

Side effects

The most common side effects associated with Alerdain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Desloratadine and pseudoephedrine combination is not recommended for use in pediatric patients under 12 years of age.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

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Comparative study between montmorillonite and Smecta on anti-dysentery effect. Based on theoretical considerations of the cellular structure, composition and physical chemical properties of hair, quantitative-structure-property-relationships (QSPR) have been proposed to predict the hair-water partition coefficient (PC) and the effective diffusion coefficient (D (e)) of solute. Effect of exposure to tick-bites on the course of lyme borreliosis in Bialowieza residents. A bimetallic hydroformylation catalyst: high regioselectivity and reactivity through homobimetallic cooperativity. After 13.5 years in vivo a 2-0 Terylene frontalis loop was excised because of an insufficiency. Differences in quality that would have resulted from the use of operator-determined exposures were calculated through use of an algorithm validated with test images of a human phantom. A combination of the advantages of different systems, such as precision and logical deduction, may be an option for developing a new system. The present study suggests that postoperative immunosuppressive therapy after cardiovascular surgeries in BD patients is important for reducing the development of serious postoperative complications.

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The concentration of CrEL in the gastrointestinal tract decreased with time with a first order rate constant of 1.73 h(-1). Evaluation of functional changes in the medial temporal region during intracarotid amobarbital procedure by use of SPECT. Parent participation in the postanesthesia care unit: fourteen years of progress at one hospital. Immunolocalization of an endogenous antigenic material of Rhinosporidium seeberi expressed only during mature sporangial development. Specific skin reaction of an immediate type in patients with allergic syndromes caused by inhalants after prolonged specific desensitization. De novo analysis of receptor binding affinity data of 8-ethenyl-xanthine antagonists to adenosine albenza drug A1 and A2a receptors. These correlations associate maternal serum IgA with gestational performance and appear to discriminate between groups which differ in that respect. High risk arterial hypertension: the role of angiotensin II receptor blockers. Bone marrow biopsies of patients with hematopoietic and lymphoid disorders - epidemiology, chromosomal aberrations and molecular pathology.

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Receiver operator characteristics (ROC) analyses showed that most gene sets were clustered much better than expected by random chance. The role of extended lymphadenectomy, including the retropancreatic and aortocaval basins, is unclear and should be attempted only in selected cases. Spontaneous resolution of spinal epidural levaquin dosing sinus infection hematomas is known to occur, and in properly selected cases, surgical intervention may not always be necessary. Effects of grouping unfamiliar cohorts, high ambient temperature and stocking density on live performance of growing pigs. These findings supported the role of wide excision in the local control of EMC, irrespective of the previous excision procedure or recurrence. Seven hundred eleven patients who received single-organ liver transplants, were at least 16 years old, and had nonfulminant liver disease. Radical excision of the tumor could thus be achieved through a craniofacial approach. Comparison of remifentanil and nitrous oxide in labour analgesia.

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A partial thymectomy or serial thymic biopsies markedly interfere with the induction of tolerance to renal allografts. For example, nonhepatic increases in serum alkaline phosphatase activity are found in young animals, in pregnant and lactating females, and in association with high fat diets. The polymerase chain reaction (PCR) was applied to detect bovine viral diarrhea virus (BVDV) by amplification of its nucleic acid sequences in cell cultures, in serum samples of persistently infected cattle, and in organ specimens of acutely diseased calves. Most of the digeneans and nematodes reported, were cosmopolitan species that occur in a range of hosts. Ninety-eight patients with resected stage B2, B3 or C (modified Astler-Coller) colon cancer who developed recurrent disease while enrolled in prospective adjuvant trials at Mayo Clinic sponsored by the North Central Cancer Treatment Group were studied to evaluate the utility of follow-up tests to detect the first recurrence of colon cancer and the outcome following various interventions for these recurrences. Extracellular regulation of interleukin (IL)-1beta through lung epithelial cells and defective IL-1 type II receptor tenormin 50 mg price in malaysia expression.

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