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Alcalm (Alprazolam)

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Alcalm is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alcalm is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alcalm may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alcalm, Alfix, Alflux, Alfresh, Alltop, Alpanol, Alpose, Alpradol, Alpram, Alprop, Alzep, Alzot, Ambulax, Andep, Anlzium, Anzocalm, Azoslip, Berest, Copax, Cozac, Cqlam, Elflu, Fluprax, Fultop, Indolam, Morecalm, Nexlpra, Normatine, Notence, Pizolam, Richpram, Selam, Selamb, Sinaday, Sozox, Tenan, Tenlax, Tenscure, Tensyn, Tenzorid, Tranax, Trustin, Unixl, Zeecam, Zolax, Zolipax, Zoloid, Zomark, Zotam

Similar Products:
Rhinocort, Famvir, Imodium, Plavix, Antabuse, Noroxin, Elocon

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alcalm XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alcalm XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alcalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Alcalm from your body, which may affect how Alcalm works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Subtotal gastrectomy outweighed total gastrectomy with better role function and less nausea/vomiting and appetite loss. Observed HTL frequencies in healthy human donors tested for tetanus-reactive helper T cells ranged from less than 1 HTL/268,749 peripheral blood mononuclear cells (PBMC) (undetectable) to 1 HTL/1486 PBMC. However, despite the increase of this ratio, the fluidity of mitochondrial lipids was found to be constant up to 10 h after the temperature shift. In the chromic and the tight silk group, an immediate and sustained mechanical allodynia was observed in the ipsilateral hind paw up to 35 days postoperatively. Glucolipotoxicity promoted HSF1 acetylation and interaction with CBP. However, the quality of evidence available on the wider health needs remains limited, but, with the move to a public health approach through health surveillance, this may increase the quality of evidence available, so influencing health outcomes for people with intellectual disabilities. A retrospective study was carried out of patients who underwent laparoscopic ventral abdominal wall hernia repair (excluding groin hernias) between January 1994 and January 1999. ChIP with sequencing revealed P-TEFb-sensitive poised RNA polymerase II at this proximal but not the previously annotated distal HEXIM1 promoter. Accurate and confirmatory diagnosis before treatment initiation is the only way to control the disease. The convenience of using hypnotherapy to encourage optimism and self-esteem in patients with breast cancer during chemotherapy treatment is discussed given its protective effect on health.

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On the other hand the alteration of the lipids may in principle modify the overall electrostatic environment of the channel, and hence the transmembrane potential, leading to an indirect modulation, i.e. All MR images of the lumbar spine (maximum of six) paid for by the health care authority were evaluated. This study is the first to evaluate the benefit of pumpkin seed oil in postmenopausal women. Charged surfactants were found to greatly inhibit HindIII activity in aqueous buffer, while non-ionic surfactants did not affect either the activity or the specificity of the restriction enzyme. Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from Germany. Race/ethnicity, obesity, health related behaviors and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial. Snail1 plays a role in the development of the invasive phenotypes of cancer, neural cell differentiation, cell division and apoptosis in tumor cells. Measurements were obtained by point counting and also by a computer-aided measuring system with reference to a constant area of the muscularis mucosa.

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The antiproliferative effect and the possible mechanism of combining with mTOR of cardamonin were investigated on A549 cells. Relations between the cell growth stimulus in levadosedimetry and the changes of the blood protein electrophoretic fractions in cancer patients. In addition, transdermal gels and spray are under development and can deliver very low doses of Nestorone a 19-norprogesterone derivative, not active orally but with high progestational activity when given via non-oral routes. Our finding, however, has been that neither inhibitory antibodies against cathepsin D, nor chemical inhibition with pepstatin, significantly decreases the rate of degradation of proteoglycan in the organ culture system. Tooth movement in the aesthetic zone may cause significant concern to the patient, and a challenging management case for the dental team. In the rat kidney, the highest densities of binding sites for all five labeled peptides were present in the glomeruli, with lower levels in the papilla, cortex, and inner band of the medulla. Since the world-wide introduction of computer tomography, neurology is undergoing a radical change which also affects the care of patients with subarachnoid hemorrhage.

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Pedestrian motor vehicle accidents are the most common cause of serious paediatric head injury in the Cape Town area. This paper will describe the rationale for, and importance of, psychological interventions for young people early in the course of bipolar disorder. Both in the Netherlands and worldwide, various clinical studies are being run on the safety and efficacy of IRE for centrally located hepatic and pancreatic tumours, which are unsuitable for the current local therapies (surgical resection, irradiation or thermal ablation) due to their anatomic location. Estimated of esophageal cancer incidence and mortality in China, 2013. For each EEG, the mean duration of 40 interburst intervals (IBIs) as well as their coefficient of variability were calculated. The hepatitis B virus core promoter is strongly activated by the liver nuclear receptor fetoprotein transcription factor or by ectopically expressed steroidogenic factor 1. B cells produce ANCAs, as well as neutrophil abnormalities and imbalances in different T-cell subtypes with excess of Th17, which perpetuate the inflammatory process. In this way any inhibitory and/or stimulatory substances present in sample preparations can be taken into account.

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Subacute sclerosing panencephalitis with atypical onset: clinical, computed tomographic, and magnetic resonance imaging correlations. This is the first mature, post-translationally processed, unit of a naturally-occurring tandemly-repetitive polyprotein to be structurally characterized from any source, and it belongs to a new structural class. Palladium(0)-catalyzed cyclization reaction of polymer-supported aryl iodides with 1,2-allenyl carboxylic acids. The Gm typing suggested that six patients had myeloma protein of the gamma1 heavy chain subclass, and one patient had a gamma3 subclass heavy chain, the remainder belonging most likely to the gamma2 heavy chain subclass since gamma2 occurs about four times as frequently as gamma4. Formation of Germa-ketenimine on the Ge(100) Surface by Adsorption of tert-Butyl Isocyanide. The kappa opioid-related anticonvulsants U-50488H and U-54494A attenuate N-methyl-D-aspartate induced brain injury in the neonatal rat. Participants were administered pretreatment on measures of psychological function and bowel symptom severity. Two hundred seventy-two nursing homes in the state of Washington. Among the different factors involved in vascular fibrosis, Angiotensin II (AngII) has special interest. The rate of elimination of chromatid-type aberrations and genomic mutations was very low in the group of liquidators exposed to higher dose of radiation.

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We present the case of an eight weeks old female infant who was admitted to the pediatric emergency department after ingesting 40 ml of vodka with her baby formula. The effect of changes in extracellular pH on P-gp functionality was examined by testing colchicine (a nonionizable P-gp substrate) in bidirectional Caco-2 and MDR1-Madine Darby canine kidney (MDCK) cell permeability assays, in which the pH of the apical and basolateral chambers was varied. Bariatric surgery improved physical capacity as well as structural and functional improvement of the heart. No significant PAcP positivity was observed in the remaining 28 foregut- and midgut-derived carcinoid tumors, except for weak focal positivity in one lung carcinoid. We selected outcome studies in which patients with documented AIDS or infection with the human immunodeficiency virus (HIV) were analyzed. The laparoscopic technique for cholecystectomy is associated with a increased rate of bile duct injuries. Vascular endothelial growth factor, basic fibroblast growth factor, transforming growth factor-beta, and platelet-derived growth factor-BB had no effect on Thy-1 mRNA. More precise and accurate activation energies for thermal electron attachment and electron affinities of SF6 , SF5 and SF4 are reported.

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In five patients with thoracic aortic aneurysms, two balloon catheters were introduced via the femoral vein to the inferior vena cava and superior vena cava and inflated before stent-graft deployment. Study into ratios of mineral metabolism in patients of different age groups suffering from osteoarthritis of the knee. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) enables minimally invasive lymph node sampling during bronchoscopy under conscious sedation. Cytologic examination of aspirated material from cysts or cystlike lesions. The effect of cyclosporine, rapamycin and FK 506 the survival following allogeneic bone marrow transplantation. Scientists have observed, however, that valuable structural information can be obtained when the gas-phase proteins are activated by collision with a surface. Novel evolved immunoglobulin (Ig)-binding molecules enhance the detection of IgM against hepatitis C virus. Substantial interobserver variation of thyroid volume and function by visual evaluation of thyroid (99m)Tc scintigraphy. VEGF mRNA and protein production were measured in polarized cells.

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Re-transurethral resection treatment for non-invasive bladder tumor. Inferences drawn from these studies and the biological plausibility of an interaction are discussed. This review will discuss the development of bendamustine, its structural and pharmacologic characteristics, and current data regarding the optimal dosing of this agent in specific clinical settings. A novel mechanism for oral controlled release of drugs by continuous degradation of a phospholipid prodrug along the intestine: in-vivo and in-vitro evaluation of an indomethacin-lecithin conjugate. Characterization of the immunoglobulin and antibody responses in histoplasmosis.

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Estimation of measurement uncertainty for the quantification of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid and its glucuronide in urine using liquid chromatography-tandem mass spectrometry. Although there has been long-standing interest in salaried models and reward methodologies, there is a dearth of systematic research associated with specific compensation models. One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan. Fever subsided soon after surgery and the patient continued antibiotics and remained free of fever at a 1-year follow-up. This study tests the hypothesis that TM can modulate antioxidants in tumor cells and render doxorubicin resistant tumor cells sensitive to doxorubicin. Avoiding toxicity from water-borne contaminants in hemodialysis: new challenges in an era of increased demand for water.

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The present study analyses the current standards and techniques of distraction and details in depth the various errors and complications that may occur due to this technique. White matter structures were analyzed in 140 subjects with both diffusion tensor imaging and voxel-based morphometry. Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. The non-steroid antirheumatic benoxaprofen was used alone in a dosage of a 1 x 600 mg tablet daily. Combined immunocytochemistry to phosphorylated neurofilament epitopes and periodic-acid methenamine silver (PAM) were used in the study of senile plaques (SP) in 6 patients with Alzheimer disease. Characterization of complex shapes embedded within volumetric data is an important step in a wide range of applications. Recently, telmisartan has been reported to prevent weight gain and improve insulin sensitivity in diet-induced obese rodents. Twenty-six patients with metastatic NETs were evaluated, including 14 carcinoid tumours, 10 pancreatic endocrine tumours and 2 medullary carcinomas of thyroid (MCTs).

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This suggests a potential role for a beta 2-GPI in the CNS damage, as a beta 2-GPI might contribute to CNS pathology by either a direct interaction with astrocytes and neurons or an interaction with cerebral vascular endothelial cells. Because the energy of interaction between a pair of subunits can depend on neighboring subunits, which we assume vary along the chain, we assign the pairwise energies of interactions according to a specified probability distribution. If BP was greater than what is a remeron pill 95 mm Hg on the first two visits, subjects were randomized into two experimental groups for 8 weeks, with cross-over from betaxolol to placebo and vice versa after 4 weeks. As a result, in the patients with JME we tried to support the theory that the underlying mechanism of the generalized seizures was the abnormal thalamocortical circuity, determining the thalamic neuronal dysfunction in MRS statistically. Colicin E5 as a new type of cytotoxin, which cleaves a specific group of tRNAs. The enzyme was also identified inside the migrating neutrophils in the reticular dermis and dermal papillae, as well as outside the cells in micro-abscesses in psoriatic skin. All aggressive or violent incidents were recorded using the Staff Observation Aggression Scale-Revised (SOAS-R). Therefore, in the present study we determined whether the metabolic syndrome (MetSyn) and type 2 diabetes mellitus (DM2) are associated with carotid artery stiffness in patients with already clinical manifestations of arterial disease. Expression is detected in whole ovary, granulosa cells, and corpora lutea. The trends of the linearity studies did not appear to be significantly affected by the problems posed by these difficult to quantitate boundary conditions.

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Saturation operation of the x-ray laser beam at 32.6 nm could be achieved with a total pump energy of less than 100 mJ. Catalytic cycles have been proposed but the mechanisms often remain speculative. Hypoxic stress alters the metabolism of tumor cells but also of macrophages, as one dominating immune cell population in most solid tumors, with subsequent changes in the microenvironment. The reaction of mandibular permanent incisors to an electric stimulator in the 6-15 year age bactrim dose pediatric uti group. Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells. When the abrupt onset and a memorized color coincide in the same object, this combination leads to even greater oculomotor capture. Prevention, case-finding and early treatment of neurological disorders. In the current study, we examine the effects of visual perspective on two forms of mental imagery in dysphoric and nondysphoric individuals.

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The knowledge of this MEN1 gene germline defect, may be used for presymptomatic identification of MEN 1 disease gene-carriers among family-members of this proband. Both enzyme activity assay and Western blot analysis revealed that T-2 toxin activated caspase-2 earlier than caspase-3, -8, and -9. However, none of these examined the functional nature of associated white matter interconnecting these cortical centers. BLM Analyzer: a software tool where do i buy metoclopramide for experiments on planar lipid bilayers. We here identify sortilin, encoded by the hypercholesterolemia-risk gene SORT1, as a high-affinity sorting receptor for PCSK9. Solid phase extraction of 5-hydroxyindole-3-acetic acid from urine and its application to HPLC and spectrophotometric methods.

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The MF alone had no effect on cell growth or survival in a clonogenic assay in either AT or normal cells. The histological diagnosis was consistent with a pigmented trichoblastoma developed within a sebaceous nevus (SN). This paper describes the background, development and implementation of an innovative Code of Research Ethics developed for a participatory research project with a Native community in Canada. Effect of education on a chest pain mnemonic on door-to-ECG time. Multiple families of proteins in the secretory granules of Paramecium tetraurelia: immunological characterization and immunocytochemical localization of trichocyst proteins. To identify outcome predictors in bone marrow transplantation (BMT) patients admitted to the intensive care unit (ICU) of The University of Texas M. Overall, these studies argue for an inherent interaction between muscarinic and 5-HT1A systems, which probably occurs beyond the postsynaptic receptors, possibly at the level of G proteins. We assessed effects of the pharmaceuticals 17alpha-ethinylestradiol and faslodex, model therapeutics designed to interact with vertebrate estrogen receptors, on endocrine biomarkers and transgenerational life-history parameters of a model invertebrate, Daphnia magna. The p21-activated kinase 4 (PAK4) is overexpressed in different cancers and promotes proliferation of cancer cells. Rational treatment of pressure irritation of the gingiva using preventive measures.

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Tumor necrosis factor-alpha in temporomandibular joint synovial fluid predicts treatment effects on pain by intra-articular glucocorticoid treatment. The sequence of events in this process is proposed to be the following: ligand-induced conformational change, receptor hyperphosphorylation and ubiquitination, internalization by an actin-dependent mechanism and subsequent delivery through at least two endocytic intermediates to the vacuole where the receptors are degraded. Clinical Pathways and the Patient Perspective in the Pursuit of Value-Based Oncology Care. Turbo-CASL is thus a promising technique for functional ASL at higher temporal resolution. To analyse the role of p21WAF1/CIP1 in gestational trophoblastic disease. A helpful mnemonic is offered both as an organizational guide for novice practitioners and as a reminder for the seasoned clinician. Furthermore, to verify the finding of concomitant loss of beta subtype thyroid hormone receptor (TRbeta) and TSHR gene expression in neoplastic thyroid tumors (Bronnegard et al. These slopes preceded the selection motrin of the signal sound at varying intervals, the longest interval was 3 s.

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In this review, I will emphasize the fact that CVC is common in patients with CKD not yet on dialysis, develops early in the course of CKD, and worsens with the decline in renal function particularly among diabetics who progressed to ESRD. FK 506 in a 14-year-old renal allograft recipient with cyclosporine-related liver nephrotoxicity: 1-year follow-up. Plant-insect communities and predator-prey ratios in field margin strips, adjacent crop fields, and prevacid 30 mg twice daily fallows. Two candidate suppressor plants were found that accelerated by 1 to 4 days the first appearance of symptoms caused by the mutant viruses. These kinetics are consistent with axonal transport of the etiological agent in a manner similar to spread of poliovirus in poliomyelitis patients. Behavior of Listeria monocytogenes at 7 degrees C in commercial turkey breast, with or without antimicrobials, after simulated contamination for manufacturing, retail and consumer settings. Moreover, little is known regarding the potential side effects of gentamicin-containing beads. We observed a positive correlation between the degree of involvement of the motor functions as measured by the ALSFRS score and the perfusion decrease of the cerebral cortex.

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We investigated the relationship between primary care supply and quality of care in England. Effect of iodine fumes on adsorbed alkaloids in activated vechicle (reaction chromatography). The difference between human H3N2 viruses and those in swine is enough that population immunity is unlikely to prevent new introductions of human IAV into pigs or vice versa, reinforcing the need to monitor and prepare for potential introductions. Association of a Low Serum Eicosapentaenoic Acid/Arachidonic Acid Ratio with the Risk of Acute Venous Thromboembolism. Simultaneously the kallikrein activity and kallikreinogen concentration as well as concentration of kininogen became enhanced can flagyl treat yeast infection whereas the bradykinin of plasma decreased. The regulation is partially dependent on downstream activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and is a direct effect on the EphA2 promoter. Endourologic management of benign ureteral strictures with and without compromised vascular supply. Dose-dependent immunomodulation of human dendritic cells by the probiotic Lactobacillus rhamnosus Lcr35.

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