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Agrus (Cetirizine)

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Agrus is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

Other names for this medication:
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Also known as: Cetirizine


{name} (cetirizine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

{name} is used in adults and children to treat cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose.

{name} is also used to treat itching and swelling caused by chronic urticaria (hives).


This section provides information on the proper use of a number of products that contain cough and cold combinations. It may not be specific to Agrus-D. Please read with care.

To help loosen mucus or phlegm in the lungs, drink a glass of water after each dose of this medicine, unless otherwise directed by your doctor.

Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

For patients taking the extended-release capsule or tablet form of this medicine:

Swallow the capsule or tablet whole. Do not crush, break, or chew before swallowing. If the capsule is too large to swallow, you may mix the contents of the capsule with applesauce, jelly, honey, or syrup and swallow without chewing.

For patients taking the extended-release oral solution or oral suspension form of this medicine:

Do not dilute with fluids or mix with other drugs.

For patients taking a combination medicine containing an antihistamine and/or aspirin or other salicylate:

Take with food or a glass of water or milk to lessen stomach irritation, if necessary.

If a combination medicine containing aspirin has a strong vinegar-like odor, do not use it. This odor means the medicine is breaking down. If you have any questions about this, check with your pharmacist.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme drowsiness, vision problems, agitation, feeling restless and then drowsy or tired, fast heartbeats, stomach pain, nausea, vomiting, trouble walking, or trouble swallowing or speaking.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Agrus are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to cetirizine or pseudoephedrine, or if you have:

narrow-angle glaucoma; severe high blood pressure (hypertension); severe coronary artery disease; if you are unable to urinate; or if you are allergic to hydroxyzine (Atarax, Vistaril).

Do not use Agrus-D if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

heart disease, coronary artery disease, high blood pressure, or heart rhythm disorder; diabetes; a thyroid disorder; glaucoma; kidney or liver disease; an enlarged prostate; or problems with urination.

FDA pregnancy category C. It is not known whether Agrus-D will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Cetirizine and pseudoephedrine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Older adults may be more likely to have side effects from Agrus-D.

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About one third had upper urinary tract changes, but none had renal failure. Receptor-mediated generation of an EDRF-like intermediate in a neuronal cell line detected by spin trapping techniques. The present study aimed to provide direct evidence that topographical differences between the processing of global and local visual elements can directly be explained by their spatial frequency content, and to study at which point in time this relation is present. Comparative analysis of the use of antimicrobials with systemic action in outpatients in the Russian Federation, Ukraine and Kazakhstan. Atmospheric concentration characteristics and gas-particle partitioning of PCBs in a rural area of eastern Germany. Framingham risk score and number of risk factors in the top quartile of the distribution of risk factors not included in the Framingham score (called composite burden) were calculated. Miniature dataloggers were used to record in-flight temperatures in aircraft wheel-wells and cargo compartments. The very low seroprevalence of HSV-2 in this sample complicated the comparisons of EBV and HSV-1 with HSV-2.

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