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Adaple (Adapalene)

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Adaple treats acne deep in the pores at the source, prevents new acne from forming and, as a result of reduced acne, restores your skin’s natural texture and tone. Adaple has been prescribed to more than 40 million people over the last 20 years.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Prilosec, Epivir, Geodon, Cardizem, Differin

Also known as: Adapalene


Adaple is a third-generation topical retinoid primarily used in the treatment of acne. Adaple is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adaple gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adaple works under the skin surface to unclog pores and clear up pimples. Adaple is also known as Adapalene, Adapen, Adaferin. Generic name of Adaple is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Adaple exactly as directed. Adaple is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adaple. Adaple should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adaple. Continue using Adaple until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adaple promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adaple dosage information

Side effects

The most common side effects associated with Adaple are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Adaple if you are allergic to adapalene.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

It is not known whether adapalene passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

It is not known whether Adaple will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Adaple is not approved for use by anyone younger than 12 years old.

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Pluripotent stem cells (induced pluripotent stem cells, iPS cells) obtained from somatic cell reprogramming are similar to the embryonic stem cells (embryonic stem cells, ES cells), which have unlimited proliferation, differentiation and memory characteristics. Inactivation of a single gene enables microaerobic growth of the obligate anaerobe Bacteroides fragilis. Spontaneous haemorrhagic perforation of gallbladder in acute cholecystitis as a complication of antiplatelet, immunosuppressant and corticosteroid therapy. Widespread haemoglobin genotyping in schools leading to genetic counselling is advocated to decrease the incidence of sickle-cell disease. A brief chronicle of cytology: from Janssen to Papanicolaou and beyond. Oral administration of Cimicifuga racemosa extract attenuates psychological and physiological stress responses. Two patients with progressive nasal obstruction due to a dentigerous cyst and a nasolabial cyst.

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Serum P I NP, in contrast to serum bone alkaline phosphatase (BAP) and intact osteocalcin (OC), did not show any significant change between before and after a hemodialysis session. Blood ketone bodies, bicarbonates, lactic acid and glucose before and after standard and all-out exercise in well trained and untrained adolescents. Irregular current spikes follow after the augmentation of the current induced when the phase-boundary potential is brought close to the mid-point potential of the transferring surfactant ions. We describe the case of a renal transplant patient who developed a disseminated HSV-2 infection with repeated urinary extravasations. Full-length cDNAs specific for oligodendrocyte- or astrocyte-specific genes were labeled with digoxigenin using the random primer method. We also studied the effect of prolonged capsaicin treatment which should predominantly impair the function of nociceptive C-fibers. Its pathogenesis remains unclear even if the initial injury likely occurs in the endothelial cells of central veins.

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Rats easily discriminate between two types of subcortical brain shock which differ in reinforcing properties. Ionizing radiation has a detrimental effect on the human body, particularly in children. The gel chromatographic behavior in 6M guanidium chloride of T-H glycopolypeptide with disulfide bonds intact as compared with its gel chromatographic behavior with disulfide bonds broken indicated that the glycopolypeptide is highly constrained by intrachain disulfide bonds. Dosage was 20 mg clomipramine during the first three days of treatment, increasing gradually over the next few weeks to a maximum daily dose of 200 mg clomipramine unless side-effects dictated a lower dose. The percentage of viable cells was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazorium bromide (MTT) assay. The synergistic effect of TLR2 and NOD2 ligands on RAC activation might be explained by the observations that bacterial lipoprotein (BLP, a TLR2 ligand) was able to upregulate NOD2 expression and the combination of BLP and muramyldipeptide (MDP, a NOD2 ligand) enhanced the expression of RICK (Rip2), the signaling molecule of NOD2. Blastocyst attachment to the lining of the mammalian uterus during early implantation involves the initial apposition of the trophoblast to the uterine epithelial surface. Loss of p16INK4a results in increased glucocorticoid receptor activity during fibrosarcoma development.

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Are prognostic factors in rheumatoid arthritis of any use in daily clinical practice?. The chemical consisted of several substances of which four (acetone, acrylates, butyl acetate and carbon disulfide) has been previously reported to induce hyposmia or anosmia in workers. This procedure has the potential to greatly expand the indications for surgery in patients suffering from AF and deserves longer-term investigation. These results demonstrate an apparent difference in the epitopes recognized by the T and B cells responding to H. To establish the requirements for real-time transfer of an ultrasound examination via telecommunication network the following tests were performed: The ultrasound data were transferred from the video out of an ultrasound system to a basis terminal of the German Telekom. On the relationships between hydrogen-sulfide-producing microorganisms and thiorhodobacteria. Improved and Improvised Sterilizing Containers for Bacteriological Petri Dishes and Pipettes. Rising to the challenge para que sirve el keflex tabletas 500 mg : will the NHS support people with long term conditions?.

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