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Accrivir (Acyclovir)
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Accrivir

Accrivir is an antiviral medication that stops a protein (an enzyme called DNA polymerase) in the herpes simplex virus (HSV) and varicella-zoster virus (VZV). Without this enzyme, the virus can't make copies of itself.

Other names for this medication:
Accrivir, Aciherpin, Acirax, Acloriv, Aclovir, Acvirall, Acvirax, Acycloguanosine, Acyclor, Acyclovir, Acylab, Alovir, Axovir, Cevirin, Civir, Cloviderm, Clovirax, Clyvir, Cutivir, Cycloex, Docvir, Herperax, Herpex, Herporax, Kayvir, Lovir, Lyrovir, Nisivir, Ocurax, Ocuvir, Ophtrhovir, Optiviral, Psyvir, Rivol, Rovir, Rowapil, Spaclovir, Trikase, Virex, Viroxit, Virucid, Vivorax, Zovir, Zoylex

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Also known as: Acyclovir

Description

Generic Accrivir is an anti-infectious medicine which is taken to fight with symptoms of herpes virus. Generic Accrivir works by killing bacteria of herpes virus. Accrivir is also known as Acyclovir, AcloVIR, Cyclovir, Herpex, Acivir, Zovir. Generic name of Generic Accrivir is Acyclovir. Brand name of Generic Accrivir is Accrivir.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Accrivir dosage information

Side effects

The most common side effects associated with Accrivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Agitation, confusion, dizziness, and drowsiness may be especially likely to occur in elderly patients who are usually more sensitive than younger adults to the central nervous system effects of acyclovir.

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Infections with S yehi largely accounted for a mild fibrinous peritonitis commonly observed among southeastern deer. Sephadex G-25 column chromatography and reverse phase HPLC revealed that SS-LI in tumor extracts was eluted just after the void volume and then in the same positions as SS-28 and SS-14. Electromyographic measurements, pressure mapping, and a wide range of other techniques have all been investigated with limited success. The elevated LIF mRNA levels in left ventricles from patients with end-stage heart failure suggest a role for LIF in the pathogenesis of CHF. Vesicular polydiacetylene sensor for colorimetric signaling of bacterial pore-forming toxin. While multiple gestation is always a negative contributing factor, continuous breastfeeding and having the mother herself as the caregiver in daytime are positive contributing factors for the growth and/or change of growth for the children born after ART. Secretin as a therapy for autism is discussed as an example of how a clinical observation rapidly grew to a widespread treatment before well-designed studies demonstrated absence of effect. Protein modifying reagents acetic anhydride, N-ethylmaleimide and mercaptoethanol all reduced binding. Omission of dithiothreitol from the cDNA synthesis reaction was found to be crucial. When the rod is rotated, a thin film of blood is formed over the internal surface of the bottles.

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Adiponectin/adiponectin receptors (AdipoR) are involved in energy homeostasis and inflammatory pathways. Thyroid dysfunction in uremia: evidence for thyroid and hypophyseal abnormalities. With measurements of atmospheric CO2 and delta13CO2, elevated N deposition was inferred as a primary factor for changes in moss C and isotopic signatures. Central nervous system tissues and cultures also failed to show viruslike particles. As cereals are eaten in large quantity by practically everyone, they are the ideal vehicles for changing the balance of nutrient intake of the whole human population. margarita were used for inoculation of transformed roots grown on M medium as it was found more favourable for germination and growth of spores.

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Enzymatic transglycosylation of natural and modified nucleosides by immobilized thermostable nucleoside phosphorylases from Geobacillus stearothermophilus. Measurement of sodium and potassium: comparison of direct-potentiometric value with indirect-potentiometric and flame-photometric values. We performed Xba I RFLP analysis on DNA from clonal cell lines derived from 11 independent papillomas and a single carcinoma derived from topically applied DMBA and compared this to RFLP on DNA from 7 clonal fibrosarcoma cell lines derived from tumors arising after subcutaneous administration of the same carcinogen. The clinical course and findings were similar in every respect to those in patients with classic idiopathic vestibular neuronitis. The hemolymph contains at least six AFPs ranging in size from 12.5 to 12.8 kDa. The established hairy root lines displayed three morphological phenotypes when cultured on hormone-free liquid Schenk and Hildebrandt medium. The mapped EuroQol indicated a utility of 0.64 for minor stroke and a value just below zero for major stroke. In neuronal neoplasms and neoplasms with neuronal differentiation, Tub-II staining was far more intense and more homogeneous than Tub-II staining in gliomas. Intravenous administration of antibodies at days 5 and 8 following challenge appeared to be optimal for suppression whereas no inhibition was seen with intravenous treatment at days 0 and 3 or at days 10 and 13. This is demonstrated by correlating ultrasound examinations and angiographies in 112 internal carotids.

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Genetic screen for modifiers of the rough eye phenotype resulting from overexpression of the Notch antagonist hairless in Drosophila. These families illustrate the importance of testing all affected individuals in a family. By analysis of color coded duplex sonography, ulcerated stenoses can be detected with high accuracy. Despite the obvious need and apparent merits, the success in the field of oral vaccination is limited due to factors including harsh gastric environment, enzymatic barrier, intestinal epithelium barrier and the fear of oral tolerance reported in case of mucosal vaccination. Quantitative data were analysed using descriptive statistics and interviews were analysed using thematic extraction. Genetic deletion or antibody blockade of alpha1beta1 integrin induces a stable plaque phenotype in ApoE-/- mice. Simultaneously, it learned an optimal number of maximally independent axes for each cluster. NAN has an HLH motif in its C-terminal region but does not have any other discernible homologies to bHLH proteins. The results indicate that the two active site tyrosines act in concert to lower the activation barrier for the alkylation step.

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The relative contribution of kainate receptors to ongoing glutamatergic activity is at present unknown. Cupreines and cupreidines: an emerging class of bifunctional cinchona organocatalysts. Left ventricular pseudoaneurysm after replacement of the mitral valve: long-term survival and spontaneous closure. Also, mechanics and sequence of dissection are enhanced and more intuitive to the surgeon using the lateral approach, and the tail of the pancreas is more easily identified. Since interleukin-18, a monocyte-derived cytokine, is increased during sepsis, decreasing the production of interleukin-18 is important in treating this condition. While the positive effect of this treatment on haemodynamics, exercise tolerance and quality of life, and a clear trend in favour of improved prognosis have been shown, there is still no concrete proof that beta-blockers reduce mortality in CHF.

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Body weight gains were significantly reduced in 200- and 400-mg TPM/m(3)-exposed males and in all smoke-exposed females compared with controls. We investigate in particular how the efficiency of the rectification is affected by the aspect ratio of the tip, the work function of the metallic elements and the occurrence of polarization resonances. The mammalian DNA mismatch-repair genes belong to a family of genes that comprise several homologs of the Escherichia coli mutS and mutL genes. Magnetic resonance (MR) scan would appear as a good alternative approach. The comparative pathology of elaeophorosis in various hosts is reviewed and discussed in terms of its pathology in Barbary sheep. Six normal male subjects per group (age range 21-35 years) were injected with 4 ng/kg, i.v., reference standard Escherichia coli (0113:h10:k) endotoxin or physiological saline.

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Effect of tetrahydrocortisol-apolipoprotein A-I complex on the secondary structure of eukaryotic DNA and its interaction with RNA-polymerase. This is thought to be an extremely rare case having multiple bone metastases of a malignant aortic body tumor. This article summarizes these two diseases as pulmonary manifestations of bioterrorism and discusses the possibility of avian influenza as a potential respiratory pathogen in biowarfare. Molecular cloning of cgrA, the gene encoding the Aspergillus nidulans ortholog of Saccharomyces cerevisiae CGR1. Use of tissue glue (butyl-2-cyanacrylate) for creation of loop ureterostomy. Using a series of GST fusion protein binding assays, co-immunofluorescence and co-immunoprecipitation experiments, we show that FIG specifically binds to the coiled coil domain-containing Q-SNARE (Q-soluble NSF attachment protein receptor) protein syntaxin 6 both in vitro and in vivo. Effect of ventilator-associated tracheobronchitis on outcome in patients without chronic respiratory failure: a case-control study. Histamine and asthma: an appraisal based on specific H1-receptor antagonism. The authors attempt to answer the question of whether patients with eating disorders experience more distortions in body image than do individuals without eating disorders.

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Sex differences and gonadal hormone influences in drug addiction and sexual behavior: progress and possibilities. These data indicate that transesophageal echocardiography leads to a clinically relevant improvement of the diagnostic potential in patients in whom cardiac masses are suspected or have to be excluded in order to ensure the safety of clinical procedures. Young (4 to 6 wk old) and adult rabbits were ventilated for 1 hr at PIPs of 15, 30, and either 45 cm H2O (young group) or 55 cm H2O (adult group). The microenvironment is now considered as an important source of potential therapeutic targets in diverse pathologies. These findings suggest that the cervix may not only be influenced by mechanical properties (stretch) and local paracrine factors but also by various stimulators and inhibitors irrespective of the myometrium. The cytotoxic effects of 5-FU and gemcitabine in AsPC-1, Capan-1, Mia-PaCa-2 and T3M4 pancreatic cancer cell lines were assessed by growth assays, and mRNA expression levels of pro-apoptotic and anti-apoptotic genes of the Bcl-2 family were analyzed by RNAse protection assays. Fundamental and clinical studies on imipenem/cilastatin sodium in the pediatric field. Dietary fiber (DF) composition and polyphenolic (PP) content of the cocoa fiber were analyzed. We identified four patients harboring HIV variants with a natural polymorphism in the membrane-proximal tyrosine-based signal Y(712)SPL or the Y(802)W(803) diaromatic motif, which are two major determinants of Env intracellular trafficking. However, neither the ls-tim nor the jetlag genetic variant alone is sufficient to disrupt light input into the central pacemaker.

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These results demonstrate that individual neurons in the mPFC that receive a functional input from the BLA actively encode emotional learning and that this process depends on DA D4 receptor stimulation in the mPFC. PCR-RFLP was undertaken in 62 cases with AD and 56 aged-matched controls. The research was conducted on two groups of 10 dogs each with clinically confirmed foreign bodies in the stomach. Six cell-free extracts have been used to characterize the nature of DNA signals and trans-acting factors responsible for the transcription enhancement of the Bombyx mori fibroin gene. Current protein-protein docking methods are often successful if experimentally determined partner proteins undergo little conformational changes upon binding. After only 4 months of treatment with hCG alone, he developed sperm in his ejaculate and his wife conceived. Phylogenetic tree and dN/dS rate ratios showed that Magmas was evolutionarily conserved.

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